47
Views
108
CrossRef citations to date
0
Altmetric
Chromosome Structure and Dynamics

Suppression of Alternative Lengthening of Telomeres by Sp100-Mediated Sequestration of the MRE11/RAD50/NBS1 Complex

, , , , &
Pages 2708-2721 | Received 14 Oct 2004, Accepted 05 Jan 2005, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Jaewon Min, Woodring E. Wright & Jerry W. Shay. (2017) Alternative Lengthening of Telomeres Mediated by Mitotic DNA Synthesis Engages Break-Induced Replication Processes. Molecular and Cellular Biology 37:20.
Read now
Rajika Arora & Claus M Azzalin. (2015) Telomere elongation chooses TERRA ALTernatives. RNA Biology 12:9, pages 938-941.
Read now
Inn Chung, Sarah Osterwald, Katharina I. Deeg & Karsten Rippe. (2012) PML body meets telomere. Nucleus 3:3, pages 263-275.
Read now
Akira Nabetani & Fuyuki Ishikawa. (2009) Unusual Telomeric DNAs in Human Telomerase-Negative Immortalized Cells. Molecular and Cellular Biology 29:3, pages 703-713.
Read now
J. Matthew Watson & Dorothy E. Shippen. (2007) Telomere Rapid Deletion Regulates Telomere Length in Arabidopsis thaliana. Molecular and Cellular Biology 27:5, pages 1706-1715.
Read now

Articles from other publishers (102)

Eric J. Sohn, Julia A. Goralsky, Jerry W. Shay & Jaewon Min. (2023) The Molecular Mechanisms and Therapeutic Prospects of Alternative Lengthening of Telomeres (ALT). Cancers 15:7, pages 1945.
Crossref
Pengju Wu, Qi Gan, Xuemei Zhang, Yunfeng Yang, Yuanxi Xiao, Qunxin She, Jinfeng Ni, Qihong Huang & Yulong Shen. (2023) The archaeal KEOPS complex possesses a functional Gon7 homolog and has an essential function independent of the cellular t 6 A modification level . mLife 2:1, pages 11-27.
Crossref
Helene E. B. Geiller, Adam Harvey, Rhiannon E. Jones, Julia W. Grimstead, Kez Cleal, Eric A. Hendrickson & Duncan M. Baird. (2022) ATRX modulates the escape from a telomere crisis. PLOS Genetics 18:11, pages e1010485.
Crossref
Alexandre de Nonneville, Sébastien Salas, François Bertucci, Alexander P Sobinoff, José Adélaïde, Arnaud Guille, Pascal Finetti, Jane R Noble, Dimitri Churikov, Max Chaffanet, Elise Lavit, Hilda A Pickett, Corinne Bouvier, Daniel Birnbaum, Roger R Reddel & Vincent Géli. (2022) TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT . EMBO Molecular Medicine 14:10.
Crossref
Lukas Frank, Anne Rademacher, Norbert Mücke, Stephan M Tirier, Emma Koeleman, Caroline Knotz, Sabrina Schumacher, Sabine A Stainczyk, Frank Westermann, Stefan Fröhling, Priya Chudasama & Karsten Rippe. (2022) ALT-FISH quantifies alternative lengthening of telomeres activity by imaging of single-stranded repeats. Nucleic Acids Research 50:11, pages e61-e61.
Crossref
Hiroshi Ebata, Tze Mun Loo & Akiko Takahashi. (2022) Telomere Maintenance and the cGAS-STING Pathway in Cancer. Cells 11:12, pages 1958.
Crossref
William A. Scott, Erum Z. Dhanji, Boris J. A. Dyakov, Ema S. Dreseris, Jonathon S. Asa, Laura J. Grange, Mila Mirceta, Christopher E. Pearson, Grant S. Stewart, Anne-Claude Gingras & Eric I. Campos. (2021) ATRX proximal protein associations boast roles beyond histone deposition. PLOS Genetics 17:11, pages e1009909.
Crossref
Stephanie M. Ackerson, Carlan Romney, P. Logan Schuck & Jason A. Stewart. (2021) To Join or Not to Join: Decision Points Along the Pathway to Double-Strand Break Repair vs. Chromosome End Protection. Frontiers in Cell and Developmental Biology 9.
Crossref
Fatemeh Sadoughi, Parisa Maleki Dana, Zatollah Asemi & Bahman Yousefi. (2021) DNA damage response and repair in osteosarcoma: Defects, regulation and therapeutic implications. DNA Repair 102, pages 103105.
Crossref
Jennifer J. Lee, Junyeop Lee & Hyunsook Lee. (2021) Alternative paths to telomere elongation. Seminars in Cell & Developmental Biology 113, pages 88-96.
Crossref
Lilit Nersisyan, Arman Simonyan, Hans Binder & Arsen Arakelyan. (2021) Telomere Maintenance Pathway Activity Analysis Enables Tissue- and Gene-Level Inferences. Frontiers in Genetics 12.
Crossref
Christopher Chin Sang, Gaelen Moore & Hyun O. Lee. 2021. Encyclopedia of Biological Chemistry III. Encyclopedia of Biological Chemistry III 113 133 .
Ahmed S. N. Alhendi & Nicola J. Royle. (2020) The absence of (TCAGGG)n repeats in some telomeres, combined with variable responses to NR2F2 depletion, suggest that this nuclear receptor plays an indirect role in the alternative lengthening of telomeres. Scientific Reports 10:1.
Crossref
Zeyue Liu, Rongrong Han, Wanwan Zhu, Jianbo Xiu, Yan Shen & Qi Xu. (2020) Inverse changes in telomere length between the blood and brain in depressive-like mice. Journal of Affective Disorders 273, pages 453-461.
Crossref
Isaac Armendáriz-Castillo, Andrés López-Cortés, Jennyfer García-Cárdenas, Patricia Guevara-Ramírez, Paola E. Leone, Andy Pérez-Villa, Verónica Yumiceba, Ana K. Zambrano, Santiago Guerrero & César Paz-y-Miño. (2020) TCGA Pan-Cancer Genomic Analysis of Alternative Lengthening of Telomeres (ALT) Related Genes. Genes 11:7, pages 834.
Crossref
Aurore Sommer & Nicola J. Royle. (2020) ALT: A Multi-Faceted Phenomenon. Genes 11:2, pages 133.
Crossref
Thomas Kent, Deanne Gracias, Samuel Shepherd & David Clynes. (2020) Alternative Lengthening of Telomeres in Pediatric Cancer: Mechanisms to Therapies. Frontiers in Oncology 9.
Crossref
Lilit Nersisyan, Lydia Hopp, Henry Loeffler-Wirth, Jörg Galle, Markus Loeffler, Arsen Arakelyan & Hans Binder. (2019) Telomere Length Maintenance and Its Transcriptional Regulation in Lynch Syndrome and Sporadic Colorectal Carcinoma. Frontiers in Oncology 9.
Crossref
Javier Rodriguez-Centeno, Cristina Manguán-García, Rosario Perona & Leandro Sastre. (2019) Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms. PLOS ONE 14:9, pages e0222909.
Crossref
Mi‐Sun Kwon, Jennifer J. Lee, Jaewon Min, Kwangwoo Hwang, Seung Gu Park, Eun‐Hye Kim, Byung Chul Kim, Jong Bhak & Hyunsook Lee. (2019) Brca2 abrogation engages with the alternative lengthening of telomeres via break‐induced replication. The FEBS Journal 286:10, pages 1841-1858.
Crossref
Valerie Turcotte-Cardin, Kevin G. Young & David J. Picketts. 2019. Chromatin Signaling and Neurological Disorders. Chromatin Signaling and Neurological Disorders 235 257 .
Emily Mason-Osann, Himabindu Gali & Rachel Litman Flynn. 2019. DNA Repair. DNA Repair 31 57 .
Paula M van Mourik, Jannie de Jong, Sushma Sharma, Alan Kavšek, Andrei Chabes & Michael Chang. (2018) Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in Saccharomyces cerevisiae . G3 Genes|Genomes|Genetics 8:8, pages 2551-2558.
Crossref
Priya Chudasama, Sadaf S. Mughal, Mathijs A. Sanders, Daniel Hübschmann, Inn Chung, Katharina I. Deeg, Siao-Han Wong, Sophie Rabe, Mario Hlevnjak, Marc Zapatka, Aurélie Ernst, Kortine Kleinheinz, Matthias Schlesner, Lina Sieverling, Barbara Klink, Evelin Schröck, Remco M. Hoogenboezem, Bernd Kasper, Christoph E. Heilig, Gerlinde Egerer, Stephan Wolf, Christof von Kalle, Roland Eils, Albrecht Stenzinger, Wilko Weichert, Hanno Glimm, Stefan Gröschel, Hans-Georg Kopp, Georg Omlor, Burkhard Lehner, Sebastian Bauer, Simon Schimmack, Alexis Ulrich, Gunhild Mechtersheimer, Karsten Rippe, Benedikt Brors, Barbara Hutter, Marcus Renner, Peter Hohenberger, Claudia Scholl & Stefan Fröhling. (2018) Integrative genomic and transcriptomic analysis of leiomyosarcoma. Nature Communications 9:1.
Crossref
Alaina R. Martinez, Zeenia Kaul, Jeffrey D. Parvin & Joanna Groden. (2017) Differential requirements for DNA repair proteins in immortalized cell lines using alternative lengthening of telomere mechanisms. Genes, Chromosomes and Cancer 56:8, pages 617-631.
Crossref
Rebecca A. Dagg, Hilda A. Pickett, Axel A. Neumann, Christine E. Napier, Jeremy D. Henson, Erdahl T. Teber, Jonathan W. Arthur, C. Patrick Reynolds, Jayne Murray, Michelle Haber, Alexander P. Sobinoff, Loretta M.S. Lau & Roger R. Reddel. (2017) Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres. Cell Reports 19:12, pages 2544-2556.
Crossref
Yue Yu, Shashank P Katiyar, Durai Sundar, Zeenia Kaul, Eijiro Miyako, Zhenya Zhang, Sunil C Kaul, Roger R Reddel & Renu Wadhwa. (2017) Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences. Cell Death & Disease 8:4, pages e2755-e2755.
Crossref
Lifang Jin, Kexin Shen, Tong Chen, Wei Yu & Huaiyu Zhang. (2017) SUMO-1 Gene Silencing Inhibits Proliferation and Promotes Apoptosis of Human Gastric Cancer SGC-7901 Cells. Cellular Physiology and Biochemistry 41:3, pages 987-998.
Crossref
João Amorim, Gustavo Santos, João Vinagre & Paula Soares. (2016) The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype. Genes 7:9, pages 66.
Crossref
Katharina I. Deeg, Inn Chung, Caroline Bauer & Karsten Rippe. (2016) Cancer Cells with Alternative Lengthening of Telomeres Do Not Display a General Hypersensitivity to ATR Inhibition. Frontiers in Oncology 6.
Crossref
Madalena C. Carneiro, Inês Pimenta de Castro & Miguel Godinho Ferreira. (2016) Telomeres in aging and disease: lessons from zebrafish. Disease Models & Mechanisms 9:7, pages 737-748.
Crossref
Priyanka Verma & Roger A. Greenberg. (2016) Noncanonical views of homology-directed DNA repair. Genes & Development 30:10, pages 1138-1154.
Crossref
N. S. Zhdanova & N. B. Rubtsov. (2016) Telomere recombination in normal mammalian cells. Russian Journal of Genetics 52:1, pages 8-16.
Crossref
Robert L. Dilley & Roger A. Greenberg. (2015) ALTernative Telomere Maintenance and Cancer. Trends in Cancer 1:2, pages 145-156.
Crossref
David Clynes, Clare Jelinska, Barbara Xella, Helena Ayyub, Caroline Scott, Matthew Mitson, Stephen Taylor, Douglas R. Higgs & Richard J. Gibbons. (2015) Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX. Nature Communications 6:1.
Crossref
Christine E. Napier, Lily I. Huschtscha, Adam Harvey, Kylie Bower, Jane R. Noble, Eric A. Hendrickson & Roger R. Reddel. (2015) ATRX represses alternative lengthening of telomeres. Oncotarget 6:18, pages 16543-16558.
Crossref
Sarah Osterwald, Katharina I. Deeg, Inn Chung, Daniel Parisotto, Stefan Wörz, Karl Rohr, Holger Erfle & Karsten Rippe. (2015) PML induces compaction, TRF2 depletion and DNA damage signaling at telomeres and promotes their alternative lengthening. Journal of Cell Science 128:10, pages 1887-1900.
Crossref
Zdenka Bartosova & Lumir Krejci. (2014) Nucleases in homologous recombination as targets for cancer therapy. FEBS Letters 588:15, pages 2446-2456.
Crossref
April Renee Sandy Gocha, Samir Acharya & Joanna Groden. (2014) WRN Loss Induces Switching of Telomerase-Independent Mechanisms of Telomere Elongation. PLoS ONE 9:4, pages e93991.
Crossref
David Clynes, Clare Jelinska, Barbara Xella, Helena Ayyub, Stephen Taylor, Matthew Mitson, Csanád Z. Bachrati, Douglas R. Higgs & Richard J. Gibbons. (2014) ATRX Dysfunction Induces Replication Defects in Primary Mouse Cells. PLoS ONE 9:3, pages e92915.
Crossref
Fiona T. M. Chang, James D. McGhie, F. Lyn Chan, Michelle C. Tang, Melissa A. Anderson, Jeffrey R. Mann, K. H. Andy Choo & Lee H. Wong. (2013) PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells. Nucleic Acids Research 41:8, pages 4447-4458.
Crossref
April Renee Sandy Gocha, Julia Harris & Joanna Groden. (2013) Alternative mechanisms of telomere lengthening: Permissive mutations, DNA repair proteins and tumorigenic progression. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 743-744, pages 142-150.
Crossref
Raina A. Tamakawa, Helen B. Fleisig & Judy M. Y. Wong. 2013. Advances in DNA Repair in Cancer Therapy. Advances in DNA Repair in Cancer Therapy 229 279 .
Dimitri Conomos, Michael D. Stutz, Mark Hills, Axel A. Neumann, Tracy M. Bryan, Roger R. Reddel & Hilda A. Pickett. (2012) Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells. Journal of Cell Biology 199:6, pages 893-906.
Crossref
Kylie Bower, Christine E. Napier, Sara L. Cole, Rebecca A. Dagg, Loretta M. S. Lau, Emma L. Duncan, Elsa L. Moy & Roger R. Reddel. (2012) Loss of Wild-Type ATRX Expression in Somatic Cell Hybrids Segregates with Activation of Alternative Lengthening of Telomeres. PLoS ONE 7:11, pages e50062.
Crossref
Jianing Xu & Michael J. McEachern. (2012) Long Telomeres Produced by Telomerase-Resistant Recombination Are Established from a Single Source and Are Subject to Extreme Sequence Scrambling. PLoS Genetics 8:11, pages e1003017.
Crossref
Courtney A. Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H. J. Petrini, Patricia A. Sung, Maria Jasin, Joseph Rosenbluh, Yaara Zwang, Barbara A. Weir, Charlie Hatton, Elena Ivanova, Laura Macconaill, Megan Hanna, William C. Hahn, Neal F. Lue, Roger R. Reddel, Yuchen Jiao, Kenneth Kinzler, Bert Vogelstein, Nickolas Papadopoulos & Alan K. Meeker. (2012) Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway. PLoS Genetics 8:7, pages e1002772.
Crossref
N. S. Zhdanova, Ju. M. Minina & N. B. Rubtsov. (2012) Mammalian telomere biology. Molecular Biology 46:4, pages 481-495.
Crossref
Jian Hu, Soyoon Sarah Hwang, Marc Liesa, Boyi Gan, Ergun Sahin, Mariela Jaskelioff, Zhihu Ding, Haoqiang Ying, Adam T. Boutin, Hailei Zhang, Shawn Johnson, Elena Ivanova, Maria Kost-Alimova, Alexei Protopopov, Yaoqi Alan Wang, Orian S. Shirihai, Lynda Chin & Ronald A. DePinho. (2012) Antitelomerase Therapy Provokes ALT and Mitochondrial Adaptive Mechanisms in Cancer. Cell 148:4, pages 651-663.
Crossref
Tania L Slatter, Xin Tan, Yi Ching Yuen, Sarah Gunningham, Sally SiYan Ma, Erin Daly, Stephen Packer, Celia Devenish, Janice A Royds & Noelyn A Hung. (2012) The alternative lengthening of telomeres pathway may operate in non-neoplastic human cells. The Journal of Pathology 226:3, pages 509-518.
Crossref
Jacklyn W Y Yong, Xiujun Yeo, Md Khan, Martin B Lee & M Prakash Hande. (2012) Stable expression of promyelocytic leukaemia (PML) protein in telomerase positive MCF7 cells results in alternative lengthening of telomeres phenotype. Genome Integrity 3:1, pages 5.
Crossref
Mounira Amor-Guéret & Jean-François Riou. 2012. DNA Topoisomerases and Cancer. DNA Topoisomerases and Cancer 155 173 .
Sarah Osterwald, Stefan Wörz, Jürgen Reymann, Frank Sieckmann, Karl Rohr, Holger Erfle & Karsten Rippe. (2012) A three-dimensional colocalization RNA interference screening platform to elucidate the alternative lengthening of telomeres pathway. Biotechnology Journal 7:1, pages 103-116.
Crossref
YI ZHANG, LIN CAI, REN-XIONG WEI, HAO HU, WEI JIN & XIAO-BIN ZHU. (2011) Different expression of alternative lengthening of telomere (ALT)-associated proteins/mRNAs in osteosarcoma cell lines. Oncology Letters 2:6, pages 1327-1332.
Crossref
Inn Chung, Heinrich Leonhardt & Karsten Rippe. (2011) De novo assembly of a PML nuclear subcompartment occurs through multiple pathways and induces telomere elongation. Journal of Cell Science 124:21, pages 3603-3618.
Crossref
S A Kamranvar & M G Masucci. (2011) The Epstein–Barr virus nuclear antigen-1 promotes telomere dysfunction via induction of oxidative stress. Leukemia 25:6, pages 1017-1025.
Crossref
A. A. Grach. (2011) Alternative telomere-lengthening mechanisms. Cytology and Genetics 45:2, pages 121-130.
Crossref
Kommu Naga Mohan, B. Sandya Rani, Pooja Swaroop Kulashreshta & Jayarama S. Kadandale. (2010) Characterization of TTAGG telomeric repeats, their interstitial occurrence and constitutively active telomerase in the mealybug Planococcus lilacinus (Homoptera; Coccoidea). Chromosoma 120:2, pages 165-175.
Crossref
Wei-Qin Jiang, Akira Nguyen, Ying Cao, Andy C.-M. Chang & Roger R. Reddel. (2011) HP1-Mediated Formation of Alternative Lengthening of Telomeres-Associated PML Bodies Requires HIRA but Not ASF1a. PLoS ONE 6:2, pages e17036.
Crossref
A. Nabetani & F. Ishikawa. (2010) Alternative lengthening of telomeres pathway: Recombination-mediated telomere maintenance mechanism in human cells. Journal of Biochemistry 149:1, pages 5-14.
Crossref
Jose A. Palacios, Daniel Herranz, Maria Luigia De Bonis, Susana Velasco, Manuel Serrano & Maria A. Blasco. (2010) SIRT1 contributes to telomere maintenance and augments global homologous recombination. Journal of Cell Biology 191:7, pages 1299-1313.
Crossref
Jeremy D. Henson & Roger R. Reddel. (2010) Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers. FEBS Letters 584:17, pages 3800-3811.
Crossref
C.V. Kavitha, Bibha Choudhary, Sathees C. Raghavan & K. Muniyappa. (2010) Differential regulation of MRN (Mre11–Rad50–Nbs1) complex subunits and telomerase activity in cancer cells. Biochemical and Biophysical Research Communications 399:4, pages 575-580.
Crossref
Anthony J. Cesare & Roger R. Reddel. (2010) Alternative lengthening of telomeres: models, mechanisms and implications. Nature Reviews Genetics 11:5, pages 319-330.
Crossref
Jian Yu, Jianping Lan, Chong Wang, Quan Wu, Yuanyuan Zhu, Xiaoyu Lai, Jie Sun, Changjiang Jin & He Huang. (2010) PML3 interacts with TRF1 and is essential for ALT-associated PML bodies assembly in U2OS cells. Cancer Letters 291:2, pages 177-186.
Crossref
R. R. Reddel. (2009) Senescence: an antiviral defense that is tumor suppressive?. Carcinogenesis 31:1, pages 19-26.
Crossref
Eros Lazzerini Denchi. 2010. Cell Cycle Deregulation in Cancer. Cell Cycle Deregulation in Cancer 127 138 .
Anthony J Cesare, Zeenia Kaul, Scott B Cohen, Christine E Napier, Hilda A Pickett, Axel A Neumann & Roger R Reddel. (2009) Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions. Nature Structural & Molecular Biology 16:12, pages 1244-1251.
Crossref
Jeremy D Henson, Ying Cao, Lily I Huschtscha, Andy C Chang, Amy Y M Au, Hilda A Pickett & Roger R Reddel. (2009) DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity. Nature Biotechnology 27:12, pages 1181-1185.
Crossref
Bettina Gruhne, Siamak Akbari Kamranvar, Maria G. Masucci & Ramakrishna Sompallae. (2009) EBV and genomic instability—A new look at the role of the virus in the pathogenesis of Burkitt's lymphoma. Seminars in Cancer Biology 19:6, pages 394-400.
Crossref
Lubomir Tomaska, Jozef Nosek, Juraj Kramara & Jack D Griffith. (2009) Telomeric circles: universal players in telomere maintenance?. Nature Structural & Molecular Biology 16:10, pages 1010-1015.
Crossref
Stephen Kearsey, Judith L Campbell, Genevieve Almouzni, Joanna Poulton, Takehiro Yasukawa, Steve Bell, Ron Laskey, Tom Kunkel, James Chong, Xinquan Ge, Julian Blow, Christian Speck, Ginger Jiang, Ellen Fanning, Helle D Ulrich, Christian Haering, James Chong, Ji-Liang Li, Tracy Bryan & Alison WaltersTracy M. Bryan. 2009. Molecular Themes in DNA Replication. Molecular Themes in DNA Replication 217 268 .
Irena DraskovicNausica ArnoultVillier SteinerSilvia Bacchetti, Patrick Lomonte & Arturo Londoño-Vallejo. (2009) Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination. Proceedings of the National Academy of Sciences 106:37, pages 15726-15731.
Crossref
Wei-Qin Jiang, Ze-Huai Zhong, Akira Nguyen, Jeremy D. Henson, Christian D. Toouli, Antony W. Braithwaite & Roger R. Reddel. (2009) Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins. Journal of Cell Biology 185:5, pages 797-810.
Crossref
Nicola J. RoyleAarón Méndez-BermúdezAthanasia GravaniClara NovoJenny FoxonJonathan WilliamsVictoria CottonAlberto Hidalgo. (2009) The role of recombination in telomere length maintenance. Biochemical Society Transactions 37:3, pages 589-595.
Crossref
Gitte De Boeck, Ramses G Forsyth, Marleen Praet & Pancras CW Hogendoorn. (2009) Telomere-associated proteins: cross-talk between telomere maintenance and telomere-lengthening mechanisms. The Journal of Pathology 217:3, pages 327-344.
Crossref
Hilda A. Pickett & Roger R. Reddel. 2009. Telomeres and Telomerase in Cancer. Telomeres and Telomerase in Cancer 127 148 .
Wei-Qin Jiang, Jeremy D. Henson, A. Neumann Axel & R. Reddel Roger. 2009. Telomeres and Telomerase in Cancer. Telomeres and Telomerase in Cancer 351 364 .
Wilhelm Palm & Titia de Lange. (2008) How Shelterin Protects Mammalian Telomeres. Annual Review of Genetics 42:1, pages 301-334.
Crossref
Xuefei Cao, Carlos Clavijo, Xu Li, H. Helen Lin, Yuan Chen, Hsiu-Ming Shih & David K. Ann. (2008) SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome. Molecular Cancer Therapeutics 7:4, pages 923-934.
Crossref
Anthony J. Cesare & Roger R. Reddel. (2008) Telomere uncapping and alternative lengthening of telomeres. Mechanisms of Ageing and Development 129:1-2, pages 99-108.
Crossref
Thalia Nittis, Lionel Guittat & Sheila A. Stewart. (2008) Alternative lengthening of telomeres (ALT) and chromatin: Is there a connection?. Biochimie 90:1, pages 5-12.
Crossref
F. Mathias Bollmann. (2007) Targeting ALT: The role of alternative lengthening of telomeres in pathogenesis and prevention of cancer. Cancer Treatment Reviews 33:8, pages 704-709.
Crossref
Ze-Huai Zhong, Wei-Qin Jiang, Anthony J. Cesare, Axel A. Neumann, Renu Wadhwa & Roger R. Reddel. (2007) Disruption of Telomere Maintenance by Depletion of the MRE11/RAD50/NBS1 Complex in Cells That Use Alternative Lengthening of Telomeres. Journal of Biological Chemistry 282:40, pages 29314-29322.
Crossref
Ken Murata, Kei Hanzawa, Fumio Kasai, Masakatsu Takeuchi, Tomoko Echigoya & Shigeru Yasumoto. (2007) Robertsonian translocation as a result of telomere shortening during replicative senescence and immortalization of bovine oviduct epithelial cells. In Vitro Cellular & Developmental Biology - Animal 43:7, pages 235-244.
Crossref
W-Q Jiang, Z-H Zhong, J D Henson & R R Reddel. (2007) Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference. Oncogene 26:32, pages 4635-4647.
Crossref
Patrick Ryan Potts & Hongtao Yu. (2007) The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins. Nature Structural & Molecular Biology 14:7, pages 581-590.
Crossref
Roger R Reddel. (2007) A SUMO ligase for ALT. Nature Structural & Molecular Biology 14:7, pages 570-571.
Crossref
Sarah A. Compton, Jun-Hyuk Choi, Anthony J. Cesare, Sezgin Özgür & Jack D. Griffith. (2007) Xrcc3 and Nbs1 Are Required for the Production of Extrachromosomal Telomeric Circles in Human Alternative Lengthening of Telomere Cells. Cancer Research 67:4, pages 1513-1519.
Crossref
Helen B. Fleisig & Judy M.Y. Wong. (2007) Telomerase as a clinical target: Current strategies and potential applications. Experimental Gerontology 42:1-2, pages 102-112.
Crossref
J. -S. Seeler, O. Bischof, K. Nacerddine & A. Dejean. 2007. Acute Promyelocytic Leukemia. Acute Promyelocytic Leukemia 49 71 .
Karel RihaMichelle L. HeacockDorothy E. Shippen. (2006) The Role of the Nonhomologous End-Joining DNA Double-Strand Break Repair Pathway in Telomere Biology. Annual Review of Genetics 40:1, pages 237-277.
Crossref
Sheila A StewartRobert A. Weinberg. (2006) Telomeres: Cancer to Human Aging. Annual Review of Cell and Developmental Biology 22:1, pages 531-557.
Crossref
Koichi Akiyama, Kosuke Yusa, Hideharu Hashimoto, Anuradha Poonepalli, Manoor Prakash Hande, Naoki Kakazu, Junji Takeda, Makoto Tachibana & Yoichi Shinkai. (2006) Rad54 is dispensable for the ALT pathway. Genes to Cells 11:11, pages 1305-1315.
Crossref
Aisha SiddiqaDavid A. CavazosRobert A. Marciniak. (2006) Targeting Telomerase. Rejuvenation Research 9:3, pages 378-390.
Crossref
J A Royds & B Iacopetta. (2006) p53 and disease: when the guardian angel fails. Cell Death & Differentiation 13:6, pages 1017-1026.
Crossref
Hung-Ji Tsai, Wei-Hsiang Huang, Tsai-Kun Li, Yun-Luen Tsai, Kou-Juey Wu, Shun-Fu Tseng & Shu-Chun Teng. (2006) Involvement of Topoisomerase III in Telomere-Telomere Recombination. Journal of Biological Chemistry 281:19, pages 13717-13723.
Crossref
Ling-Jie Kong, Alison R. Meloni & Joseph R. Nevins. (2006) The Rb-Related p130 Protein Controls Telomere Lengthening through an Interaction with a Rad50-Interacting Protein, RINT-1. Molecular Cell 22:1, pages 63-71.
Crossref
Ken André Olaussen, Karine Dubrana, Julien Domont, Jean-Philippe Spano, Laure Sabatier & Jean-Charles Soria. (2006) Telomeres and telomerase as targets for anticancer drug development. Critical Reviews in Oncology/Hematology 57:3, pages 191-214.
Crossref
Maria A Cerone, Chantal Autexier, J Arturo Londoño-Vallejo & Silvia Bacchetti. (2005) A human cell line that maintains telomeres in the absence of telomerase and of key markers of ALT. Oncogene 24:53, pages 7893-7901.
Crossref
Alessandra Muntoni & Roger R. Reddel. (2005) The first molecular details of ALT in human tumor cells. Human Molecular Genetics 14:suppl_2, pages R191-R196.
Crossref
J. Matthew Watson, Petra Bulankova, Karel Riha, Dorothy E. Shippen & Boris Vyskot. (2005) Telomerase-independent cell survival in Arabidopsis thaliana. The Plant Journal 43:5, pages 662-674.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.