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Molecular and Cellular Biology Volume 25, 2005 - Issue 7
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Mammalian Genetic Models with Minimal or Complex Phenotypes

ZPR1 Is Essential for Survival and Is Required for Localization of the Survival Motor Neurons (SMN) Protein to Cajal Bodies

Laxman Gangwani1 Program in Molecular Medicine, University of Massachusetts Medical School
,
Richard A. Flavell2 Howard Hughes Medical Institute and Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut
&
Roger J. Davis1 Program in Molecular Medicine, University of Massachusetts Medical School;3 Howard Hughes Medical Institute, Worcester, MassachusettsCorrespondence[email protected]
Pages 2744-2756 | Received 11 Nov 2004, Accepted 21 Dec 2004, Published online: 27 Mar 2023

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Lian He, Yusai Xie, Yusong Qiu & Yong Zhang. (2023) Pan-Cancer Profiling and Digital Pathology Analysis Reveal Negative Prognostic Biomarker ZPR1 Associated with Immune Infiltration and Treatment Response in Hepatocellular Carcinoma. Journal of Hepatocellular Carcinoma 10, pages 1309-1325.
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Bin Liu, Xiaojing Xing, Xiang Li, Qianxue Guo, Tonghong Xu & Ke Xu. (2018) ZNF259 promotes breast cancer cells invasion and migration via ERK/GSK3β/snail signaling. Cancer Management and Research 10, pages 3159-3168.
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Yuemei Shan, Wei Cao, Tao Wang, Guiyang Jiang, Yong Zhang & Xianghong Yang. (2017) ZNF259 inhibits non-small cell lung cancer cells proliferation and invasion by FAK-AKT signaling. Cancer Management and Research 9, pages 879-889.
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Amanda C. Raimer, Kelsey M. Gray & A. Gregory Matera. (2017) SMN - A chaperone for nuclear RNP social occasions?. RNA Biology 14:6, pages 701-711.
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Ping Xu & Roger J. Davis. (2010) c-Jun NH2-Terminal Kinase Is Required for Lineage-Specific Differentiation but Not Stem Cell Self-Renewal. Molecular and Cellular Biology 30:6, pages 1329-1340.
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Michael D. Wilson, Diana Wang, Rebecca Wagner, Hilde Breyssens, Marina Gertsenstein, Corrinne Lobe, Xin Lu, Andras Nagy, Robert D. Burke, Ben F. Koop & Perry L. Howard. (2008) ARS2 Is a Conserved Eukaryotic Gene Essential for Early Mammalian Development. Molecular and Cellular Biology 28:5, pages 1503-1514.
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Ryan S. Anderton, Bruno P. Meloni, Frank L. Mastaglia & Sherif Boulos. (2013) Spinal Muscular Atrophy and the Antiapoptotic Role of Survival of Motor Neuron (SMN) Protein. Molecular Neurobiology 47:2, pages 821-832.
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Jinhua Li, Wei Sima, Bo Ouyang, Zhidan Luo, Changxian Yang, Zhibiao Ye & Hanxia Li. (2012) Identification and Expression Pattern of a ZPR1 Gene in Wild Tomato (Solanum Pennellii). Plant Molecular Biology Reporter 31:2, pages 409-417.
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Saif Ahmad, Yi Wang, Gouse M. Shaik, Arthur H. Burghes & Laxman Gangwani. (2012) The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy. Human Molecular Genetics 21:12, pages 2745-2758.
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Ping Xu, Madhumita Das, Judith Reilly & Roger J. Davis. (2011) JNK regulates FoxO-dependent autophagy in neurons. Genes & Development 25:4, pages 310-322.
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Ruben J. Cauchi. (2010) SMN and Gemins: ‘We are family’ … or are we?. BioEssays 32:12, pages 1077-1089.
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Adrian G. Todd, Robert Morse, Debra J. Shaw, Howard Stebbings & Philip J. Young. (2010) Analysis of SMN-neurite granules: Core Cajal body components are absent from SMN-cytoplasmic complexes. Biochemical and Biophysical Research Communications 397:3, pages 479-485.
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Jinfang Zhang, Feiyun Zhang & Xiaofeng Zheng. (2010) Depletion of hCINAP by RNA interference causes defects in Cajal body formation, histone transcription, and cell viability. Cellular and Molecular Life Sciences 67:11, pages 1907-1918.
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Michael D. Hebert. (2010) Phosphorylation and the Cajal body: Modification in search of function. Archives of Biochemistry and Biophysics 496:2, pages 69-76.
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Michael P. Walker, T.K. Rajendra, Luciano Saieva, Jennifer L. Fuentes, Livio Pellizzoni & A. Gregory Matera. (2008) SMN complex localizes to the sarcomeric Z-disc and is a proteolytic target of calpain. Human Molecular Genetics 17:21, pages 3399-3410.
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Glenn E. Morris. (2008) The Cajal body. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1783:11, pages 2108-2115.
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Ashwini K. Mishra, Laxman Gangwani, Roger J. Davis & David G. Lambright. (2007) Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes. Proceedings of the National Academy of Sciences 104:35, pages 13930-13935.
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Laxman Gangwani. (2006) Deficiency of the Zinc Finger Protein ZPR1 Causes Defects in Transcription and Cell Cycle Progression. Journal of Biological Chemistry 281:52, pages 40330-40340.
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Mario Cioce, Séverine Boulon, A. Gregory Matera & Angus I. Lamond. (2006) UV-induced fragmentation of Cajal bodies. Journal of Cell Biology 175:3, pages 401-413.
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David Staněk & Karla M. Neugebauer. (2006) The Cajal body: a meeting place for spliceosomal snRNPs in the nuclear maze. Chromosoma 115:5, pages 343-354.
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Brunhilde Wirth, Lars Brichta & Eric Hahnen. (2006) Spinal Muscular Atrophy: From Gene to Therapy. Seminars in Pediatric Neurology 13:2, pages 121-131.
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Beth DoranNorberto Gherbesi, Gregory Hendricks, Richard A. Flavell, Roger J. Davis & Laxman Gangwani. (2006) Deficiency of the zinc finger protein ZPR1 causes neurodegeneration. Proceedings of the National Academy of Sciences 103:19, pages 7471-7475.
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Benoît Renvoisé, Kevinee Khoobarry, Marie-Claude Gendron, Christian Cibert, Louis Viollet & Suzie Lefebvre. (2006) Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells. Journal of Cell Science 119:4, pages 680-692.
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