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Article

The Multifunctional RNA-Binding Protein La Is Required for Mouse Development and for the Establishment of EmbryonicStem Cells

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Pages 1445-1451 | Received 15 Sep 2005, Accepted 18 Nov 2005, Published online: 27 Mar 2023

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Read on this site (6)

Daniele Hasler, Gunter Meister & Utz Fischer. (2021) Stabilize and connect: the role of LARP7 in nuclear non-coding RNA metabolism. RNA Biology 18:2, pages 290-303.
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Mark A. Bayfield, Jyotsna Vinayak, Kyra Kerkhofs & Farnaz Mansouri-Noori. (2021) La proteins couple use of sequence-specific and non-specific binding modes to engage RNA substrates. RNA Biology 18:2, pages 168-177.
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Venkatesh Kota, Gunhild Sommer, E. Starr Hazard, Gary Hardiman, Jeffery L. Twiss & Tilman Heise. (2018) SUMO Modification of the RNA-Binding Protein La Regulates Cell Proliferation and STAT3 Protein Stability. Molecular and Cellular Biology 38:2.
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Nathan H. Blewett, James R. Iben, Sergei Gaidamakov & Richard J. Maraia. (2017) La Deletion from Mouse Brain Alters Pre-tRNA Metabolism and Accumulation of Pre-5.8S rRNA, with Neuron Death and Reactive Astrocytosis. Molecular and Cellular Biology 37:10.
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Sandy Mattijssen & Richard J. Maraia. (2016) LARP4 Is Regulated by Tumor Necrosis Factor Alpha in a Tristetraprolin-Dependent Manner. Molecular and Cellular Biology 36:4, pages 574-584.
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Sarah L. French, Yvonne N. Osheim, David A. Schneider, Martha L. Sikes, Cesar F. Fernandez, Laura A. Copela, Vikram A. Misra, Masayasu Nomura, Sandra L. Wolin & Ann L. Beyer. (2008) Visual Analysis of the Yeast 5S rRNA Gene Transcriptome: Regulation and Role of La Protein. Molecular and Cellular Biology 28:14, pages 4576-4587.
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Jarred M. Whitlock, Evgenia Leikina, Kamran Melikov, Luis Fernandez De Castro, Sandy Mattijssen, Richard J. Maraia, Michael T. Collins & Leonid V. Chernomordik. (2023) Cell surface-bound La protein regulates the cell fusion stage of osteoclastogenesis. Nature Communications 14:1.
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Kyra Kerkhofs, Jyoti Garg, Étienne Fafard-Couture, Sherif Abou Elela, Michelle S. Scott, Ronald E. Pearlman & Mark A. Bayfield. (2022) Altered tRNA processing is linked to a distinct and unusual La protein in Tetrahymena thermophila. Nature Communications 13:1.
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Nhan L. T. Nguyen & Nelly Panté. (2022) Bioinformatics and Functional Analysis of a New Nuclear Localization Sequence of the Influenza A Virus Nucleoprotein. Cells 11:19, pages 2957.
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Hongming Guo, Yuchao Cui, Linjuan Huang, Li Ge, Xiaorong Xu, Danyang Xue, Ming Tang, Jingsheng Zheng, Yin Yi & Liang Chen. (2022) The RNA binding protein OsLa influences grain and anther development in rice . The Plant Journal 110:5, pages 1397-1414.
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Vasilios Liapis, William Tieu, Nicole L. Wittwer, Tessa Gargett, Andreas Evdokiou, Prab Takhar, Stacey E. Rudd, Paul S. Donnelly, Michael P. Brown & Alexander H. Staudacher. (2021) Positron Emission Tomographic Imaging of Tumor Cell Death Using Zirconium-89-Labeled APOMAB® Following Cisplatin Chemotherapy in Lung and Ovarian Cancer Xenograft Models. Molecular Imaging and Biology 23:6, pages 914-928.
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Norbert Ha, Nan Ding, Ru Hong, Rubing Liu, Xavier Roca, Yingyuan Luo, Xiaowei Duan, Xiao Wang, Peiling Ni, Haiyang Wu, Li-Feng Zhang & Lingyi Chen. (2021) The lupus autoantigen La/Ssb is an Xist -binding protein involved in Xist folding and cloud formation . Nucleic Acids Research 49:20, pages 11596-11613.
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Seong Heon Kim, Bi-Oh Park, Kidae Kim, Byoung Chul Park, Sung Goo Park, Jeong-Hoon Kim & Sunhong Kim. (2021) Sjögren Syndrome antigen B regulates LIN28-let-7 axis in Caenorhabditis elegans and human. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1864:3, pages 194684.
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Miriam Almagor, Yishai Levin, Rona Halevy Amiran, Sheila Fieldust, Yael Harir, Yuval Or & Zeev Shoham. (2020) Spontaneous in vitro hatching of the human blastocyst: the proteomics of initially hatching cells. In Vitro Cellular & Developmental Biology - Animal 56:10, pages 859-865.
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Gunhild Sommer, Christina Sendlmeier & Tilman Heise. 2020. RNA Chaperones. RNA Chaperones 121 136 .
Dritan Liko, Louise Mitchell, Kirsteen J. Campbell, Rachel A. Ridgway, Carolyn Jones, Kate Dudek, Ayala King, Sheila Bryson, David Stevenson, Karen Blyth, Douglas Strathdee, Jennifer P. Morton, Thomas G. Bird, John R. P. Knight, Anne E. Willis & Owen J. Sansom. (2019) Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas. Cell Death & Differentiation 26:12, pages 2535-2550.
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Hee Cho, Wooseong Lee, Geon-Woo Kim, Seung-Hoon Lee, Jae-Su Moon, Minwoo Kim, Hyun Seok Kim & Jong-Won Oh. (2019) Regulation of La/SSB-dependent viral gene expression by pre-tRNA 3′ trailer-derived tRNA fragments. Nucleic Acids Research 47:18, pages 9888-9901.
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G. Aneeshkumar Arimbasseri. (2018) Interactions between RNAP III transcription machinery and tRNA processing factors. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1861:4, pages 354-360.
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Nathan H. Blewett & Richard J. Maraia. (2018) La involvement in tRNA and other RNA processing events including differences among yeast and other eukaryotes. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1861:4, pages 361-372.
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Xing Dong, Xuchun Qiu, Shunlong Meng, Hai Xu, Xiangyang Wu & Ming Yang. (2018) Proteomic profile and toxicity pathway analysis in zebrafish embryos exposed to bisphenol A and di-n-butyl phthalate at environmentally relevant levels. Chemosphere 193, pages 313-320.
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Richard J. Maraia, Sandy Mattijssen, Isabel Cruz‐Gallardo & Maria R. Conte. (2017) The La and related RNA ‐binding proteins (LARPs): structures, functions, and evolving perspectives . WIREs RNA 8:6.
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Virginia K. Vachon & Graeme L. Conn. (2016) Adenovirus VA RNA: An essential pro-viral non-coding RNA. Virus Research 212, pages 39-52.
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Earl Silverman, Jill Buyon & Edgar Jaeggi. 2016. Textbook of Pediatric Rheumatology. Textbook of Pediatric Rheumatology 336 350.e8 .
Danielle L Cullinane, Tamjid A Chowdhury & Kenneth C Kleene. (2015) Mechanisms of translational repression of the Smcp mRNA in round spermatids. REPRODUCTION 149:1, pages 43-54.
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Diana Guallar & Jianlong Wang. (2014) RNA-binding proteins in pluripotency, differentiation, and reprogramming. Frontiers in Biology 9:5, pages 389-409.
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Meghdad Yeganeh, Ehsan Seyedjafari, Farnaz Akbari Kamrani & Nasser Ghaemi. (2013) RNA-binding protein Rbm47 binds to Nanog in mouse embryonic stem cells. Molecular Biology Reports 40:7, pages 4391-4396.
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Chunyang Liang, Ke Xiong, Keith E. Szulwach, Yi Zhang, Zhaohui Wang, Junmin Peng, Mingui Fu, Peng Jin, Hiroshi I. Suzuki & Qinghua Liu. (2013) Sjögren Syndrome Antigen B (SSB)/La Promotes Global MicroRNA Expression by Binding MicroRNA Precursors through Stem-Loop Recognition. Journal of Biological Chemistry 288:1, pages 723-736.
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Vera Cherkasova, Luis Lopez Maury, Dagmar Bacikova, Kevin Pridham, Jürg Bähler & Richard J. Maraia. (2012) Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p . Molecular Biology of the Cell 23:3, pages 480-491.
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Amir R. Naeeni, Maria R. Conte & Mark A. Bayfield. (2012) RNA Chaperone Activity of Human La Protein Is Mediated by Variant RNA Recognition Motif. Journal of Biological Chemistry 287:8, pages 5472-5482.
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Weikang Tao, Xianzhi Mao, Joseph P Davide, Bruce Ng, Mingmei Cai, Paul A Burke, Alan B Sachs & Laura Sepp-Lorenzino. (2011) Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses. Molecular Therapy 19:3, pages 567-575.
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Jakob Suckale, Olivia Wendling, Jimmy Masjkur, Melanie Jäger, Carla Münster, Konstantinos Anastassiadis, A. Francis Stewart & Michele Solimena. (2011) PTBP1 Is Required for Embryonic Development before Gastrulation. PLoS ONE 6:2, pages e16992.
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G Sommer, J Dittmann, J Kuehnert, K Reumann, P E Schwartz, H Will, B L Coulter, M T Smith & T Heise. (2010) The RNA-binding protein La contributes to cell proliferation and CCND1 expression. Oncogene 30:4, pages 434-444.
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Ruiping Zheng, Zhen Shen, Vidisha Tripathi, Zhenyu Xuan, Susan M. Freier, C. Frank Bennett, Supriya G. Prasanth & Kannanganattu V. Prasanth. (2010) Polypurine-repeat-containing RNAs: a novel class of long non-coding RNA in mammalian cells. Journal of Cell Science 123:21, pages 3734-3744.
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John G. Routsias & Athanasios G. Tzioufas. (2010) B-cell epitopes of the intracellular autoantigens Ro/SSA and La/SSB: Tools to study the regulation of the autoimmune response. Journal of Autoimmunity 35:3, pages 256-264.
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Mark A. Bayfield, Ruiqing Yang & Richard J. Maraia. (2010) Conserved and divergent features of the structure and function of La and La-related proteins (LARPs). Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1799:5-6, pages 365-378.
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Paola Dongiovanni, Anna Ludovica Fracanzani, Gaetano Cairo, Chiara Paola Megazzini, Stefano Gatti, Raffaela Rametta, Silvia Fargion & Luca Valenti. (2010) Iron-Dependent Regulation of MDM2 Influences p53 Activity and Hepatic Carcinogenesis. The American Journal of Pathology 176:2, pages 1006-1017.
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Katherine Ewen, Mark Baker, Dagmar Wilhelm, R. John Aitken & Peter Koopman. (2009) Global Survey of Protein Expression during Gonadal Sex Determination in Mice. Molecular & Cellular Proteomics 8:12, pages 2624-2641.
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Fares Al-Ejeh, Jocelyn M. Darby, Chris Tsopelas, Douglas Smyth, Jim Manavis & Michael P. Brown. (2009) APOMAB®, a La-Specific Monoclonal Antibody, Detects the Apoptotic Tumor Response to Life-Prolonging and DNA-Damaging Chemotherapy. PLoS ONE 4:2, pages e4558.
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Haifeng Weng, Chul Kim, Christos Valavanis, Zhaohui Wang & Lawrence Schwartz. (2009) Acheron, an novel LA antigen family member, binds to cask and forms a complex with id transcription factors. Cellular and Molecular Biology Letters 14:2.
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Kagnew Hailesellasse Sene, Christopher J Porter, Gareth Palidwor, Carolina Perez-Iratxeta, Enrique M Muro, Pearl A Campbell, Michael A Rudnicki & Miguel A Andrade-Navarro. (2007) Gene function in early mouse embryonic stem cell differentiation. BMC Genomics 8:1.
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Fares Al-Ejeh, Jocelyn M. Darby & Michael P. Brown. (2007) The La Autoantigen Is a Malignancy-Associated Cell Death Target That Is Induced by DNA-Damaging Drugs. Clinical Cancer Research 13:18, pages 5509s-5518s.
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Sophie Fleurdépine, Jean-Marc Deragon, Martine Devic, Jocelyne Guilleminot & Cécile Bousquet-Antonelli. (2007) A bona fide La protein is required for embryogenesis in Arabidopsis thaliana. Nucleic Acids Research 35:10, pages 3306-3321.
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Christos Valavanis, Zhaohui Wang, Danhui Sun, Michael Vaine & Lawrence M. Schwartz. (2007) Acheron, a novel member of the Lupus Antigen family, is induced during the programmed cell death of skeletal muscles in the moth Manduca sexta. Gene 393:1-2, pages 101-109.
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S.L. WOLIN & E.J. WURTMANN. (2006) Molecular Chaperones and Quality Control in Noncoding RNA Biogenesis. Cold Spring Harbor Symposia on Quantitative Biology 71:0, pages 505-511.
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