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Molecular and Cellular Biology Volume 26, 2006 - Issue 4
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Article

Pin1 Regulates Centrosome Duplication, and Its Overexpression Induces Centrosome Amplification, Chromosome Instability, and Oncogenesis

Futoshi SuizuCancer Biology Program, Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts02215
,
Akihide RyoCancer Biology Program, Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts02215
,
Gerburg WulfCancer Biology Program, Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts02215
,
Jormay LimCancer Biology Program, Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts02215
&
Kun Ping LuCancer Biology Program, Division of Hematology/Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts02215Correspondence[email protected]
Pages 1463-1479 | Received 09 Aug 2005, Accepted 22 Nov 2005, Published online: 27 Mar 2023

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John H. Bannon, Darragh S. O’Donovan, Susan M.E. Kennelly & Margaret M. Mc Gee. (2012) The peptidyl prolyl isomerase cyclophilin A localizes at the centrosome and the midbody and is required for cytokinesis. Cell Cycle 11:7, pages 1340-1353.
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Prashant Rajbhandari, Greg Finn, Natalia M. Solodin, Kiran K. Singarapu, Sarata C. Sahu, John L. Markley, Kelley J. Kadunc, Stephanie J. Ellison-Zelski, Anastasia Kariagina, Sandra Z. Haslam, Kun Ping Lu & Elaine T. Alarid. (2012) Regulation of Estrogen Receptor α N-Terminus Conformation and Function by Peptidyl Prolyl Isomerase Pin1. Molecular and Cellular Biology 32:2, pages 445-457.
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Antonietta Rosella Farina, Antonella Tacconelli, Lucia Cappabianca, Gesilia Cea, Sonia Panella, Antonella Chioda, Alessandra Romanelli, Carlo Pedone, Alberto Gulino & Andrew Reay Mackay. (2009) The Alternative TrkAIII Splice Variant Targets the Centrosome and Promotes Genetic Instability. Molecular and Cellular Biology 29:17, pages 4812-4830.
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Articles from other publishers (75)

Kamal Tabti, Larbi Elmchichi, Abdelouahid Sbai, Hamid Maghat, Mohammed Bouachrine, Tahar Lakhlifi & Arabinda Ghosh. (2022) In silico design of novel PIN1 inhibitors by combined of 3D-QSAR, molecular docking, molecular dynamic simulation and ADMET studies. Journal of Molecular Structure 1253, pages 132291.
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Yupeng Liu, Fangying Yu, Suhuan Dai, Tingting Meng, Yun Zhu, Guoxi Qiu, Lijuan Wen, Xueqing Zhou, Hong Yuan & Fuqiang Hu. (2021) All-Trans Retinoic Acid and Doxorubicin Delivery by Folic Acid Modified Polymeric Micelles for the Modulation of Pin1-Mediated DOX-Induced Breast Cancer Stemness and Metastasis. Molecular Pharmaceutics 18:11, pages 3966-3978.
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Hsiang-Hao Chuang, Yen-Yi Zhen, Yu-Chen Tsai, Cheng-Hao Chuang, Ming-Shyan Huang, Michael Hsiao & Chih-Jen Yang. (2021) Targeting Pin1 for Modulation of Cell Motility and Cancer Therapy. Biomedicines 9:4, pages 359.
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Karuna Mittal, Jaspreet Kaur, Meghan Jaczko, Guanhao Wei, Michael S. Toss, Emad A. Rakha, Emiel Adrianus Maria Janssen, Håvard Søiland, Omer Kucuk, Michelle Dian Reid, Meenakshi V. Gupta & Ritu Aneja. (2020) Centrosome amplification: a quantifiable cancer cell trait with prognostic value in solid malignancies. Cancer and Metastasis Reviews 40:1, pages 319-339.
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Long Wang, Ying Zhou, Dongmei Chen & Tae Ho Lee. (2020) Peptidyl-Prolyl Cis/Trans Isomerase Pin1 and Alzheimer’s Disease. Frontiers in Cell and Developmental Biology 8.
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Ayesha Z. Sherzai, Melvin Parasram, Janelle M. Haider & Dean Sherzai. (2020) Alzheimer Disease and Cancer. Alzheimer Disease & Associated Disorders 34:2, pages 122-127.
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Ji Hoon Yu, Chun Young Im & Sang-Hyun Min. (2020) Function of PIN1 in Cancer Development and Its Inhibitors as Cancer Therapeutics. Frontiers in Cell and Developmental Biology 8.
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Dongmei Chen, Long Wang & Tae Ho Lee. (2020) Post-translational Modifications of the Peptidyl-Prolyl Isomerase Pin1. Frontiers in Cell and Developmental Biology 8.
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Dongmei Chen, Xiao Z. Zhou & Tae H. Lee. (2019) Death-Associated Protein Kinase 1 as a Promising Drug Target in Cancer and Alzheimer’s Disease. Recent Patents on Anti-Cancer Drug Discovery 14:2, pages 144-157.
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Shuhui Yu, Yali Zhang, Yuyun Wu, Hongying Yang, Yang Chen, Yingbin Yang & Ze Zhang. (2019) Subcellular localization of mutated β‐catenins with different incidences of cis ‐peptide bonds at the Xaa246‐P247 site in HepG2 cells . The FASEB Journal 33:5, pages 6574-6583.
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Prem Khanal, Benjamin Yeung, Yulei Zhao & Xiaolong Yang. (2019) Identification of Prolyl isomerase Pin1 as a novel positive regulator of YAP/TAZ in breast cancer cells. Scientific Reports 9:1.
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Alessandro Zannini, Alessandra Rustighi, Elena Campaner & Giannino Del Sal. (2019) Oncogenic Hijacking of the PIN1 Signaling Network. Frontiers in Oncology 9.
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Michael Schumann, Miroslav Malešević, Erik Hinze, Sebastian Mathea, Marat Meleshin, Mike Schutkowski, Wolfgang Haehnel & Cordelia Schiene-Fischer. (2018) Regulation of the Minichromosome Maintenance Protein 3 (MCM3) Chromatin Binding by the Prolyl Isomerase Pin1. Journal of Molecular Biology 430:24, pages 5169-5181.
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Yang Chen, Ya-ran Wu, Hong-ying Yang, Xin-zhe Li, Meng-meng Jie, Chang-jiang Hu, Yu-yun Wu, Shi-ming Yang & Ying-bin Yang. (2018) Prolyl isomerase Pin1: a promoter of cancer and a target for therapy. Cell Death & Disease 9:9.
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