Advanced search
Publication Cover
Molecular and Cellular Biology Volume 26, 2006 - Issue 4
Submit an article Journal homepage
25
Views
25
CrossRef citations to date
0
Altmetric
Article

An E2F Binding-Deficient Rb1 Protein Partially Rescues Developmental Defects Associated with Rb1 Nullizygosity

Huifang Sun1 Department of Pharmacology & Therapeutics, Roswell Park Cancer Institute, Buffalo, New York14263
,
Yanjie Chang1 Department of Pharmacology & Therapeutics, Roswell Park Cancer Institute, Buffalo, New York14263
,
Brett Schweers2 Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee38105
,
Michael A. Dyer2 Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee38105
,
Xiaojing Zhang1 Department of Pharmacology & Therapeutics, Roswell Park Cancer Institute, Buffalo, New York14263
,
Simon W. Hayward3 Departments of Urologic Surgery and Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee37235
&
David W. Goodrich1 Department of Pharmacology & Therapeutics, Roswell Park Cancer Institute, Buffalo, New York14263Correspondence[email protected]
 show all
Pages 1527-1537 | Received 31 Aug 2005, Accepted 04 Dec 2005, Published online: 27 Mar 2023

Citations (25)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Meenalakshmi Chinnam, Xiaoling Wang, Xiaojing Zhang & David W. Goodrich. (2016) Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice. Molecular and Cellular Biology 36:11, pages 1621-1627.
Read now
Michael Korenjak, Endre Anderssen, Sridhar Ramaswamy, Johnathan R. Whetstine & Nicholas J. Dyson. (2012) RBF Binding to both Canonical E2F Targets and Noncanonical Targets Depends on Functional dE2F/dDP Complexes. Molecular and Cellular Biology 32:21, pages 4375-4387.
Read now
Alexandra Dirlam, Benjamin T. Spike & Kay F. Macleod. (2007) Deregulated E2f-2 Underlies Cell Cycle and Maturation Defects in Retinoblastoma Null Erythroblasts. Molecular and Cellular Biology 27:24, pages 8713-8728.
Read now

Articles from other publishers (22)

Ha TH Vu, Haninder Kaur, Kelby R Kies, Rebekah R Starks & Geetu Tuteja. (2023) Identifying novel regulators of placental development using time-series transcriptome data. Life Science Alliance 6:2, pages e202201788.
Crossref
Vishnu Suresh Babu, Ashwin Mallipatna, Deepak SA, Gagan Dudeja, Ramaraj Kannan, Rohit Shetty, Archana Padmanabhan Nair, Seetharamanjaneyulu Gundimeda, Shyam S. Chaurasia, Navin Kumar Verma, Rajamani Lakshminarayanan, Stephane Heymans, Veluchamy A. Barathi, Nilanjan Guha & Arkasubhra Ghosh. (2022) Integrated Analysis of Cancer Tissue and Vitreous Humor from Retinoblastoma Eyes Reveals Unique Tumor-Specific Metabolic and Cellular Pathways in Advanced and Non-Advanced Tumors. Cells 11:10, pages 1668.
Crossref
Joel D. Pearson, Katherine Huang, Marek Pacal, Sean R. McCurdy, Suying Lu, Arthur Aubry, Tao Yu, Kristine M. Wadosky, Letian Zhang, Tao Wang, Alex Gregorieff, Mohammad Ahmad, Helen Dimaras, Ellen Langille, Susan P.C. Cole, Philippe P. Monnier, Benjamin H. Lok, Ming-Sound Tsao, Nagako Akeno, Daniel Schramek, Kathryn A. Wikenheiser-Brokamp, Erik S. Knudsen, Agnieszka K. Witkiewicz, Jeffrey L. Wrana, David W. Goodrich & Rod Bremner. (2021) Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity. Cancer Cell 39:8, pages 1115-1134.e12.
Crossref
Naiyan Wen, Baofeng Guo, Hongwu Zheng, Libo Xu, Hang Liang, Qian Wang, Ding Wang, Xuyang Chen, Shengnan Zhang, Yang Li & Ling Zhang. (2019) Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway. International Journal of Oncology.
Crossref
Maxwell M. Goodrich, Ramzi Talhouk, Xiaojing Zhang & David W. Goodrich. (2018) An approach for controlling the timing and order of engineered mutations in mice. genesis 56:8, pages e23243.
Crossref
Michael J. Thwaites, Matthew J. Cecchini, Srikanth Talluri, Daniel T. Passos, Jasmyne Carnevale & Frederick A. Dick. (2017) Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control. Cell Division 12:1.
Crossref
Issam Aldiri, Itsuki Ajioka, Beisi Xu, Jiakun Zhang, Xiang Chen, Claudia Benavente, David Finkelstein, Dianna Johnson, Jennifer Akiyama, Len A. Pennacchio & Michael A. Dyer. (2015) Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma. Development 142:23, pages 4092-4106.
Crossref
Shikha Tarang, Songila M. S. R. Doi, Channabasavaiah B. Gurumurthy, Donald Harms, Rolen Quadros & Sonia M. Rocha-Sanchez. (2015) Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model. Frontiers in Cellular Neuroscience 9.
Crossref
Boris Popov & Nikolay Petrov. (2014) pRb-E2F signaling in life of mesenchymal stem cells: Cell cycle, cell fate, and cell differentiation. Genes & Diseases 1:2, pages 174-187.
Crossref
Hideaki Toki, Maki Inoue, Osamu Minowa, Hiromi Motegi, Yuriko Saiki, Shigeharu Wakana, Hiroshi Masuya, Yoichi Gondo, Toshihiko Shiroishi, Ryoji Yao & Tetsuo Noda. (2014) Novel retinoblastoma mutation abrogating the interaction to E 2 F 2/3, but not E 2 F 1, led to selective suppression of thyroid tumors . Cancer Science 105:10, pages 1360-1368.
Crossref
Huifang SunYanqing WangMeenalakshmi ChinnamXiaojing ZhangSimon W. HaywardBarbara A. FosterAlexander Y. Nikitin, Marcia Wills & David W. Goodrich. (2010) E2f binding-deficient Rb1 protein suppresses prostate tumor progression in vivo . Proceedings of the National Academy of Sciences 108:2, pages 704-709.
Crossref
B. V. Popov, S. M. Watt, J. M. Rosanov & L. -S. Chang. (2010) A structural pocket mutation of pRb increases its affinity for E2F4, which is coupled with activation of muscle differentiation. Molecular Biology 44:2, pages 287-297.
Crossref
Rafael Linden, Rodrigo A.P. Martins, Mariana S. Silveira, Helena L. Borges, Alfred Sholl-Franco, Lucianne Fragel-Madeira & Ana Carolina Dudenhoeffer-Carneiro. 2010. Perspectives of Stem Cells. Perspectives of Stem Cells 191 230 .
Marijana Samardzija, Stephan C. F. Neuhauss, Sandrine Joly, Malaika Kurz-Levin & Christian Grimm. 2010. Animal Models for Retinal Diseases. Animal Models for Retinal Diseases 51 79 .
Bingxiu Xiao, Junming Guo, Ying Miao, Zhen Jiang, Rong Huan, Yuanyuan Zhang, Dong Li & Jiuchang Zhong. (2009) Detection of miR-106a in gastric carcinoma and its clinical significance. Clinica Chimica Acta 400:1-2, pages 97-102.
Crossref
Hai Xiao, Xiaojing Zhang & David W. Goodrich. (2009) Construction of a dual affinity tagged allele of the Rb1 tumor suppressor gene in the mouse . genesis, pages NA-NA.
Crossref
A Nemajerova, F Talos, U M Moll & O Petrenko. (2008) Rb function is required for E1A-induced S-phase checkpoint activation. Cell Death & Differentiation 15:9, pages 1440-1449.
Crossref
Alexandra Dirlam & Kay F. Macleod. 2005. The Cancer Handbook. The Cancer Handbook.
David MacPherson & Michael A. Dyer. (2007) Retinoblastoma: From the Two-Hit Hypothesis to Targeted Chemotherapy. Cancer Research 67:16, pages 7547-7550.
Crossref
Elizaveta V. Benevolenskaya. (2007) Histone H3K4 demethylases are essential in development and differentiationThis paper is one of a selection of papers published in this Special Issue, entitled 28th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.. Biochemistry and Cell Biology 85:4, pages 435-443.
Crossref
Stacy L Donovan, Brett Schweers, Rodrigo Martins, Dianna Johnson & Michael A Dyer. (2006) Compensation by tumor suppressor genes during retinal development in mice and humans. BMC Biology 4:1.
Crossref
D W Goodrich. (2006) The retinoblastoma tumor-suppressor gene, the exception that proves the rule. Oncogene 25:38, pages 5233-5243.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.