Citations (59)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Rohan Bir Singh, Prakash Gupta, Akash Kartik, Naba Farooqui, Sachi Singhal, Sukhman Shergill, Kanwar Partap Singh & Aniruddha Agarwal. (2021) Ocular Manifestations of Neuronal Ceroid Lipofuscinoses. Seminars in Ophthalmology 36:7, pages 582-595.
Read now
Read now
Suman Gupta, Rakesh Kumar Singh, Sunanda Dastidar & Abhijit Ray. (2008) Cysteine cathepsin S as an immunomodulatory target: present and future trends. Expert Opinion on Therapeutic Targets 12:3, pages 291-299.
Read now
Read now
Articles from other publishers (57)
Anthony T. Ginnetti, Daniel V. Paone, Kausik K. Nanda, Jing Li, Marina Busuek, Scott A. Johnson, Jun Lu, Stephen M. Soisson, Ronald Robinson, John Fisher, Andrea Webber, Gregg Wesolowski, Bennett Ma, Le Duong, Steven Carroll, Christopher S. Burgey & Shawn J. Stachel. (2022) Lead optimization of cathepsin K inhibitors for the treatment of Osteoarthritis. Bioorganic & Medicinal Chemistry Letters 74, pages 128927.
Crossref
Crossref
Laxmi Kirola, Ashim Mukherjee & Mousumi Mutsuddi. (2022) Recent Updates on the Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Molecular Neurobiology 59:9, pages 5673-5694.
Crossref
Crossref
Garrett Bullock, Gary S. Johnson, Tendai Mhlanga-Mutangadura, Scott C. Petesch, Samantha Thompson, Sandra Goebbels & Martin L. Katz. (2022) Lysosomal storage disease associated with a CNP sequence variant in Dalmatian dogs. Gene 830, pages 146513.
Crossref
Crossref
Konrad Kaminiów, Sylwia Kozak & Justyna Paprocka. (2022) Recent Insight into the Genetic Basis, Clinical Features, and Diagnostic Methods for Neuronal Ceroid Lipofuscinosis. International Journal of Molecular Sciences 23:10, pages 5729.
Crossref
Crossref
Janko Kos, Ana Mitrović, Milica Perišić Nanut & Anja Pišlar. (2022) Lysosomal peptidases—intriguing roles in cancer progression and neurodegeneration. FEBS Open Bio 12:4, pages 708-738.
Crossref
Crossref
Andreas Tuermer, Simone Mausbach, Edgar Kaade, Markus Damme, Marc Sylvester, Volkmar Gieselmann & Melanie Thelen. (2021) CLN6 deficiency causes selective changes in the lysosomal protein composition. PROTEOMICS 21:19, pages 2100043.
Crossref
Crossref
Jessica Root, Paola Merino, Austin Nuckols, Michelle Johnson & Thomas Kukar. (2021) Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis. Neurobiology of Disease 154, pages 105360.
Crossref
Crossref
Kimberly L. Carey, Geraldine L.C. Paulus, Lingfei Wang, Dale R. Balce, Jessica W. Luo, Phil Bergman, Ianina C. Ferder, Lingjia Kong, Nicole Renaud, Shantanu Singh, Maria Kost-Alimova, Beat Nyfeler, Kara G. Lassen, Herbert W. Virgin & Ramnik J. Xavier. (2020) TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41. Cell Reports 33:6, pages 108371.
Crossref
Crossref
Robert J. Huber, Stephanie M. Hughes, Wenfei Liu, Alan Morgan, Richard I. Tuxworth & Claire Russell. (2020) The contribution of multicellular model organisms to neuronal ceroid lipofuscinosis research. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866:9, pages 165614.
Crossref
Crossref
Hemanth R. Nelvagal, Jenny Lange, Keigo Takahashi, Marta A. Tarczyluk-Wells & Jonathan D. Cooper. (2020) Pathomechanisms in the neuronal ceroid lipofuscinoses. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1866:9, pages 165570.
Crossref
Crossref
Logan Langin, Tyler B. Johnson, Attila D. Kovács, David A. Pearce & Jill M. Weimer. (2020) A tailored Cln3Q352X mouse model for testing therapeutic interventions in CLN3 Batten disease. Scientific Reports 10:1.
Crossref
Crossref
Anil B. Mukherjee, Abhilash P. Appu, Tamal Sadhukhan, Sydney Casey, Avisek Mondal, Zhongjian Zhang & Maria B. Bagh. (2019) Emerging new roles of the lysosome and neuronal ceroid lipofuscinoses. Molecular Neurodegeneration 14:1.
Crossref
Crossref
Natalie A. Villani, Garrett Bullock, Jennifer R. Michaels, Osamu Yamato, Dennis P. O'Brien, Tendai Mhlanga-Mutangadura, Gary S. Johnson & Martin L. Katz. (2019) A mixed breed dog with neuronal ceroid lipofuscinosis is homozygous for a CLN5 nonsense mutation previously identified in Border Collies and Australian Cattle Dogs. Molecular Genetics and Metabolism 127:1, pages 107-115.
Crossref
Crossref
Henrike Kristen, Isabel Sastre, Teresa Muñoz-Galdeano, Maria Recuero, Jesus Aldudo & Maria J. Bullido. (2018) The lysosome system is severely impaired in a cellular model of neurodegeneration induced by HSV-1 and oxidative stress. Neurobiology of Aging 68, pages 5-17.
Crossref
Crossref
Alexandra Moreno-García, Alejandra Kun, Olga Calero, Miguel Medina & Miguel Calero. (2018) An Overview of the Role of Lipofuscin in Age-Related Neurodegeneration. Frontiers in Neuroscience 12.
Crossref
Crossref
Lovro Kramer, Dušan Turk & Boris Turk. (2017) The Future of Cysteine Cathepsins in Disease Management. Trends in Pharmacological Sciences 38:10, pages 873-898.
Crossref
Crossref
Davide Marotta, Elisa Tinelli & Sara E. Mole. (2017) NCLs and ER: A stressful relationship. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1863:6, pages 1273-1281.
Crossref
Crossref
Stephanie Ketterer, Alejandro Gomez-Auli, Larissa E. Hillebrand, Agnese Petrera, Anett Ketscher & Thomas Reinheckel. (2017) Inherited diseases caused by mutations in cathepsin protease genes. The FEBS Journal 284:10, pages 1437-1454.
Crossref
Crossref
Mansi Manchanda, Nishat Fatima & Shyam Singh Chauhan. 2017. Proteases in Physiology and Pathology. Proteases in Physiology and Pathology
217
256
.
Emily Mackey, Saravanan Ayyadurai, Calvin S. Pohl, Susan D’ Costa, Yihang Li & Adam J. Moeser. (2016) Sexual dimorphism in the mast cell transcriptome and the pathophysiological responses to immunological and psychological stress. Biology of Sex Differences 7:1.
Crossref
Crossref
Veronika Stoka, Vito Turk & Boris Turk. (2016) Lysosomal cathepsins and their regulation in aging and neurodegeneration. Ageing Research Reviews 32, pages 22-37.
Crossref
Crossref
David Pires, Joana Marques, João Palma Pombo, Nuno Carmo, Paulo Bettencourt, Olivier Neyrolles, Geanncarlo Lugo-Villarino & Elsa Anes. (2016) Role of Cathepsins in Mycobacterium tuberculosis Survival in Human Macrophages. Scientific Reports 6:1.
Crossref
Crossref
Romina Kohan, Favio Pesaola, Norberto Guelbert, Patricia Pons, Ana María Oller-Ramírez, Gisela Rautenberg, Adriana Becerra, Katherine Sims, Winnie Xin, Inés Adriana Cismondi & Inés Noher de Halac. (2015) The neuronal ceroid lipofuscinoses program: A translational research experience in Argentina. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1852:10, pages 2301-2311.
Crossref
Crossref
Jaime Cárcel-Trullols, Attila D. Kovács & David A. Pearce. (2015) Cell biology of the NCL proteins: What they do and don't do. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1852:10, pages 2242-2255.
Crossref
Crossref
Kiterie M.E. Faller, Rodrigo Gutierrez-Quintana, Alamin Mohammed, Ahad A. Rahim, Richard I. Tuxworth, Kim Wager & Michael Bond. (2015) The neuronal ceroid lipofuscinoses: Opportunities from model systems. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1852:10, pages 2267-2278.
Crossref
Crossref
Janina Schmitz, Norbert Furtmann, Moritz Ponert, Maxim Frizler, Reik Löser, Ulrike Bartz, Jürgen Bajorath & Michael Gütschow. (2015) Active Site Mapping of Human Cathepsin F with Dipeptide Nitrile Inhibitors. ChemMedChem 10:8, pages 1365-1377.
Crossref
Crossref
Judith Peters, Andrea Rittger, Rebecca Weisner, Johannes Knabbe, Friederike Zunke, Michelle Rothaug, Markus Damme, Samuel F. Berkovic, Judith Blanz, Paul Saftig & Michael Schwake. (2015) Lysosomal integral membrane protein type-2 (LIMP-2/SCARB2) is a substrate of cathepsin-F, a cysteine protease mutated in type-B-Kufs-disease. Biochemical and Biophysical Research Communications 457:3, pages 334-340.
Crossref
Crossref
Masayuki Suyama, Masato Koike, Daisuke Asaoka, Hiroki Mori, Masako Oguro, Takashi Ueno, Akihito Nagahara, Sumio Watanabe & Yasuo Uchiyama. (2014) Increased Immunoreactivity of Cathepsins in the Rat Esophagus under Chronic Acid Reflux Esophagitis. Journal of Histochemistry & Cytochemistry 62:9, pages 645-660.
Crossref
Crossref
Anja Pišlar & Janko Kos. (2013) Cysteine Cathepsins in Neurological Disorders. Molecular Neurobiology 49:2, pages 1017-1030.
Crossref
Crossref
Katrin Kollmann, Kristiina Uusi-Rauva, Enzo Scifo, Jaana Tyynelä, Anu Jalanko & Thomas Braulke. (2013) Cell biology and function of neuronal ceroid lipofuscinosis-related proteins. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1832:11, pages 1866-1881.
Crossref
Crossref
Michael Bond, Sophia-Martha kleine Holthaus, Imke Tammen, Guy Tear & Claire Russell. (2013) Use of model organisms for the study of neuronal ceroid lipofuscinosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1832:11, pages 1842-1865.
Crossref
Crossref
Barbara Jerič, Iztok Dolenc, Marko Mihelič, Martina Klarić, Tina Zavašnik-Bergant, Gregor Gunčar, Boris Turk, Vito Turk & Veronika Stoka. (2013) N-terminally truncated forms of human cathepsin F accumulate in aggresome-like inclusions. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1833:10, pages 2254-2266.
Crossref
Crossref
K. R. Smith, H.-H. M. Dahl, L. Canafoglia, E. Andermann, J. Damiano, M. Morbin, A. C. Bruni, G. Giaccone, P. Cossette, P. Saftig, J. Grotzinger, M. Schwake, F. Andermann, J. F. Staropoli, K. B. Sims, S. E. Mole, S. Franceschetti, N. A. Alexander, J. D. Cooper, H. A. Chapman, S. Carpenter, S. F. Berkovic & M. Bahlo. (2013) Cathepsin F mutations cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis. Human Molecular Genetics 22:7, pages 1417-1423.
Crossref
Crossref
Romina Kohan, María Noelia Carabelos, Winnie Xin, Katherine Sims, Norberto Guelbert, Inés Adriana Cismondi, Patricia Pons, Graciela Irene Alonso, Mónica Troncoso, Scarlet Witting, David A. Pearce, Raquel Dodelson de Kremer, Ana María Oller-Ramírez & Inés Noher de Halac. (2013) Neuronal ceroid lipofuscinosis type CLN2: A new rationale for the construction of phenotypic subgroups based on a survey of 25 cases in South America. Gene 516:1, pages 114-121.
Crossref
Crossref
Dieter Brömme. 2013. Handbook of Proteolytic Enzymes. Handbook of Proteolytic Enzymes
1792
1795
.
Martina Gansz, Ursula Kern, Christoph Peters & Thomas Reinheckel. 2013. Proteases: Structure and Function. Proteases: Structure and Function
217
233
.
Ann H. Erickson, Ciro Isidoro, Lukas Mach & John S. Mort. 2013. Proteases: Structure and Function. Proteases: Structure and Function
127
173
.
Maxim Frizler, Janina Schmitz, Anna-Christina Schulz-Fincke & Michael Gütschow. (2012) Selective Nitrile Inhibitors To Modulate the Proteolytic Synergism of Cathepsins S and F. Journal of Medicinal Chemistry 55:12, pages 5982-5986.
Crossref
Crossref
Wolfgang Kaufmann, Brad Bolon, Alys Bradley, Mark Butt, Stephanie Czasch, Robert H. Garman, Catherine George, Sibylle Gröters, Georg Krinke, Peter Little, Jenny McKay, Isao Narama, Deepa Rao, Makoto Shibutani & Robert Sills. (2012) Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems. Toxicologic Pathology 40:4_suppl, pages 87S-157S.
Crossref
Crossref
Vito Turk, Veronika Stoka, Olga Vasiljeva, Miha Renko, Tao Sun, Boris Turk & Dušan Turk. (2012) Cysteine cathepsins: From structure, function and regulation to new frontiers. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1824:1, pages 68-88.
Crossref
Crossref
Rose-Mary N. Boustany & Mohamad K. El-Bitar. 2012. Swaiman's Pediatric Neurology. Swaiman's Pediatric Neurology
518
543
.
I. Rajan, R. Read, D. L. Small, J. Perrard & P. Vogel. (2010)
An Alternative Splicing Variant in
Clcn7
–/–
Mice Prevents Osteopetrosis but Not Neural and Retinal Degeneration
. Veterinary Pathology 48:3, pages 663-675.
Crossref
Crossref
Michael Reich, Fang Zou, Marcin Sieńczyk, Jozef Oleksyszyn, Bernhard O. Boehm & Timo Burster. (2011) Invariant chain processing is independent of cathepsin variation between primary human B cells/dendritic cells and B-lymphoblastoid cells. Cellular Immunology 269:2, pages 96-103.
Crossref
Crossref
Huiwen Zhang, Don J. Mahuran & John W. Callahan. (2010) Identification of proteins in the ceroid-like autofluorescent aggregates from liver lysosomes of Beige, a mouse model for human Chediak–Higashi syndrome. Molecular Genetics and Metabolism 99:4, pages 389-395.
Crossref
Crossref
Valerie Cullen, Maria Lindfors, Juliana Ng, Anders Paetau, Erika Swinton, Piotr Kolodziej, Heather Boston, Paul Saftig, John Woulfe, Mel B Feany, Liisa Myllykangas, Michael G Schlossmacher & Jaana Tyynelä. (2009) Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo. Molecular Brain 2:1.
Crossref
Crossref
Phillip I. Bird, Joseph A. Trapani & José A. Villadangos. (2009) Endolysosomal proteases and their inhibitors in immunity. Nature Reviews Immunology 9:12, pages 871-882.
Crossref
Crossref
Boris Turk & Vito Turk. (2009) Lysosomes as “Suicide Bags” in Cell Death: Myth or Reality?. Journal of Biological Chemistry 284:33, pages 21783-21787.
Crossref
Crossref
Jenny Miu, Nicholas H. Hunt & Helen J. Ball. (2008) Predominance of Interferon-Related Responses in the Brain during Murine Malaria, as Identified by Microarray Analysis. Infection and Immunity 76:5, pages 1812-1824.
Crossref
Crossref
Dinesh Rakheja, Srinivas B. Narayan & Michael J. Bennett. (2008) The function of CLN3P, the Batten disease protein. Molecular Genetics and Metabolism 93:3, pages 269-274.
Crossref
Crossref
Tina Zavašnik-Bergant & Boris Turk. (2007) Cysteine proteases: destruction ability versus immunomodulation capacity in immune cells. bchm 388:11, pages 1141-1149.
Crossref
Crossref
Suzanne P. M. Lutgens, Kitty B. J. M. Cleutjens, Mat J. A. P. Daemen & Sylvia Heeneman. (2007) Cathepsin cysteine proteases in cardiovascular disease. The FASEB Journal 21:12, pages 3029-3041.
Crossref
Crossref
Eija Siintola, Meral Topcu, Nina Aula, Hannes Lohi, Berge A. Minassian, Andrew D. Paterson, Xiao-Qing Liu, Callum Wilson, Ulla Lahtinen, Anna-Kaisa Anttonen & Anna-Elina Lehesjoki. (2007) The Novel Neuronal Ceroid Lipofuscinosis Gene MFSD8 Encodes a Putative Lysosomal Transporter. The American Journal of Human Genetics 81:1, pages 136-146.
Crossref
Crossref
Judith A. Hobert & Glyn Dawson. (2007) A novel role of the Batten disease gene CLN3: Association with BMP synthesis. Biochemical and Biophysical Research Communications 358:1, pages 111-116.
Crossref
Crossref
Judith A. Hobert & Glyn Dawson. (2006) Neuronal ceroid lipofuscinoses therapeutic strategies: Past, present and future. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1762:10, pages 945-953.
Crossref
Crossref
Jonathan D. Cooper, Claire Russell & Hannah M. Mitchison. (2006) Progress towards understanding disease mechanisms in small vertebrate models of neuronal ceroid lipofuscinosis. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1762:10, pages 873-889.
Crossref
Crossref
Aija Kyttälä, Ulla Lahtinen, Thomas Braulke & Sandra L. Hofmann. (2006) Functional biology of the neuronal ceroid lipofuscinoses (NCL) proteins. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1762:10, pages 920-933.
Crossref
Crossref
Eija Siintola, Anna-Elina Lehesjoki & Sara E Mole. (2006) Molecular genetics of the NCLs — status and perspectives. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1762:10, pages 857-864.
Crossref
Crossref