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Article

The Spt4p Subunit of Yeast DSIF Stimulates Association of the Paf1 Complex with Elongating RNA Polymerase II

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Pages 3135-3148 | Received 08 Dec 2005, Accepted 12 Jan 2006, Published online: 27 Mar 2023

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Manasi K. Mayekar, Richard G. Gardner & Karen M. Arndt. (2013) The Recruitment of the Saccharomyces cerevisiae Paf1 Complex to Active Genes Requires a Domain of Rtf1 That Directly Interacts with the Spt4-Spt5 Complex. Molecular and Cellular Biology 33:16, pages 3259-3273.
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Marla M. Spain & Chhabi K. Govind. (2011) A role for phosphorylated Pol II CTD in modulating transcription coupled histone dynamics. Transcription 2:2, pages 78-81.
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Toshitsugu Fujita & Werner Schlegel. (2010) Promoter-proximal pausing of RNA polymerase II: an opportunity to regulate gene transcription. Journal of Receptors and Signal Transduction 30:1, pages 31-42.
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Daniel S. Ginsburg, Chhabi K. Govind & Alan G. Hinnebusch. (2009) NuA4 Lysine Acetyltransferase Esa1 Is Targeted to Coding Regions and Stimulates Transcription Elongation with Gcn5. Molecular and Cellular Biology 29:24, pages 6473-6487.
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Ying Liu, Linda Warfield, Chao Zhang, Jie Luo, Jasmina Allen, Walter H. Lang, Jeffrey Ranish, Kevan M. Shokat & Steven Hahn. (2009) Phosphorylation of the Transcription Elongation Factor Spt5 by Yeast Bur1 Kinase Stimulates Recruitment of the PAF Complex. Molecular and Cellular Biology 29:17, pages 4852-4863.
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Marcie H. Warner, Kelli L. Roinick & Karen M. Arndt. (2007) Rtf1 Is a Multifunctional Component of the Paf1 Complex That Regulates Gene Expression by Directing Cotranscriptional Histone Modification. Molecular and Cellular Biology 27:17, pages 6103-6115.
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Chi-Ming Wong, Hongfang Qiu, Cuihua Hu, Jinsheng Dong & Alan G. Hinnebusch. (2007) Yeast Cap Binding Complex Impedes Recruitment of Cleavage Factor IA to Weak Termination Sites. Molecular and Cellular Biology 27:18, pages 6520-6531.
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Mariela Reyes-Reyes & Michael Hampsey. (2007) Role for the Ssu72 C-Terminal Domain Phosphatase in RNA Polymerase II Transcription Elongation. Molecular and Cellular Biology 27:3, pages 926-936.
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Nirmalya Saha, James Ropa, Lili Chen, Hsiangyu Hu, Maria Mysliwski, Ann Friedman, Ivan Maillard & Andrew G. Muntean. (2019) The PAF1c Subunit CDC73 Is Required for Mouse Hematopoietic Stem Cell Maintenance but Displays Leukemia-Specific Gene Regulation. Stem Cell Reports 12:5, pages 1069-1083.
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Seychelle M. Vos, Lucas Farnung, Marc Boehning, Christoph Wigge, Andreas Linden, Henning Urlaub & Patrick Cramer. (2018) Structure of activated transcription complex Pol II–DSIF–PAF–SPT6. Nature 560:7720, pages 607-612.
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J Serio, J Ropa, W Chen, M Mysliwski, N Saha, L Chen, J Wang, H Miao, T Cierpicki, J Grembecka & A G Muntean. (2017) The PAF complex regulation of Prmt5 facilitates the progression and maintenance of MLL fusion leukemia. Oncogene 37:4, pages 450-460.
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Yuki Yamaguchi, Hirotaka Shibata & Hiroshi Handa. (2013) Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:1, pages 98-104.
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Brett N. Tomson & Karen M. Arndt. (2013) The many roles of the conserved eukaryotic Paf1 complex in regulating transcription, histone modifications, and disease states. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:1, pages 116-126.
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Hongfang Qiu, Cuihua Hu, Naseem A Gaur & Alan G Hinnebusch. (2012) Pol II CTD kinases Bur1 and Kin28 promote Spt5 CTR-independent recruitment of Paf1 complex. The EMBO Journal 31:16, pages 3494-3505.
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Christopher G. Amrich, Christopher P. Davis, Walter P. Rogal, Margaret K. Shirra, Annie Heroux, Richard G. Gardner, Karen M. Arndt & Andrew P. VanDemark. (2012) Cdc73 Subunit of Paf1 Complex Contains C-terminal Ras-like Domain That Promotes Association of Paf1 Complex with Chromatin. Journal of Biological Chemistry 287:14, pages 10863-10875.
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Elia M. Crisucci & Karen M. Arndt. (2011) The Roles of the Paf1 Complex and Associated Histone Modifications in Regulating Gene Expression. Genetics Research International 2011, pages 1-15.
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Justin A. Pruneski, Sarah J. Hainer, Kostadin O. Petrov & Joseph A. Martens. (2011) The Paf1 Complex Represses SER3 Transcription in Saccharomyces cerevisiae by Facilitating Intergenic Transcription-Dependent Nucleosome Occupancy of the SER3 Promoter . Eukaryotic Cell 10:10, pages 1283-1294.
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Danielle Tatum, Wentao Li, Margaret Placer & Shisheng Li. (2011) Diverse Roles of RNA Polymerase II-associated Factor 1 Complex in Different Subpathways of Nucleotide Excision Repair. Journal of Biological Chemistry 286:35, pages 30304-30313.
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Katja Helenius, Ying Yang, Timofey V. Tselykh, Heli K. J. Pessa, Mikko J. Frilander & Tomi P. Mäkelä. (2011) Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover. Nucleic Acids Research 39:12, pages 5025-5035.
Crossref
Susan J. Anderson, Martha L. Sikes, Yinfeng Zhang, Sarah L. French, Shilpa Salgia, Ann L. Beyer, Masayasu Nomura & David A. Schneider. (2011) The Transcription Elongation Factor Spt5 Influences Transcription by RNA Polymerase I Positively and Negatively. Journal of Biological Chemistry 286:21, pages 18816-18824.
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Simon Drouin, Louise Laramée, Pierre-Étienne Jacques, Audrey Forest, Maxime Bergeron & François Robert. (2010) DSIF and RNA Polymerase II CTD Phosphorylation Coordinate the Recruitment of Rpd3S to Actively Transcribed Genes. PLoS Genetics 6:10, pages e1001173.
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Jessica L. Dermody & Stephen Buratowski. (2010) Leo1 Subunit of the Yeast Paf1 Complex Binds RNA and Contributes to Complex Recruitment*. Journal of Biological Chemistry 285:44, pages 33671-33679.
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Zhifa Shen, Anik St-Denis & Pascal Chartrand. (2010) Cotranscriptional recruitment of She2p by RNA pol II elongation factor Spt4–Spt5/DSIF promotes mRNA localization to the yeast bud. Genes & Development 24:17, pages 1914-1926.
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Chhabi K. Govind, Hongfang Qiu, Daniel S. Ginsburg, Chun Ruan, Kimberly Hofmeyer, Cuihua Hu, Venkatesh Swaminathan, Jerry L. Workman, Bing Li & Alan G. Hinnebusch. (2010) Phosphorylated Pol II CTD Recruits Multiple HDACs, Including Rpd3C(S), for Methylation-Dependent Deacetylation of ORF Nucleosomes. Molecular Cell 39:2, pages 234-246.
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Xiaoying Bai, Jonghwan Kim, Zhongan Yang, Michael J. Jurynec, Thomas E. Akie, Joseph Lee, Jocelyn LeBlanc, Anna Sessa, Hong Jiang, Anthony DiBiase, Yi Zhou, David J. Grunwald, Shuo Lin, Alan B. Cantor, Stuart H. Orkin & Leonard I. Zon. (2010) TIF1γ Controls Erythroid Cell Fate by Regulating Transcription Elongation. Cell 142:1, pages 133-143.
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Damien Coudreuse, Harm van Bakel, Monique Dewez, Julie Soutourina, Tim Parnell, Jean Vandenhaute, Brad Cairns, Michel Werner & Damien Hermand. (2010) A Gene-Specific Requirement of RNA Polymerase II CTD Phosphorylation for Sexual Differentiation in S. pombe. Current Biology 20:12, pages 1053-1064.
Crossref
Yinfeng Zhang, Archer D. SmithIVIV, Matthew B. Renfrow & David A. Schneider. (2010) The RNA Polymerase-associated Factor 1 Complex (Paf1C) Directly Increases the Elongation Rate of RNA Polymerase I and Is Required for Efficient Regulation of rRNA Synthesis. Journal of Biological Chemistry 285:19, pages 14152-14159.
Crossref
Judith A. Jaehning. (2010) The Paf1 complex: Platform or player in RNA polymerase II transcription?. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1799:5-6, pages 379-388.
Crossref
Jaehoon Kim, Mohamed Guermah & Robert G. Roeder. (2010) The Human PAF1 Complex Acts in Chromatin Transcription Elongation Both Independently and Cooperatively with SII/TFIIS. Cell 140:4, pages 491-503.
Crossref
Yexi Chen, Yuki Yamaguchi, Yuta Tsugeno, Junichi Yamamoto, Tomoko Yamada, Mitsuhiro Nakamura, Koji Hisatake & Hiroshi Handa. (2009) DSIF, the Paf1 complex, and Tat-SF1 have nonredundant, cooperative roles in RNA polymerase II elongation. Genes & Development 23:23, pages 2765-2777.
Crossref
Beate Schwer, Susanne Schneider, Yi Pei, Anna Aronova & Stewart Shuman. (2009) Characterization of the Schizosaccharomyces pombe Spt5-Spt4 complex . RNA 15:7, pages 1241-1250.
Crossref
Karen Zhou, Wei Hung William Kuo, Jeffrey Fillingham & Jack F. Greenblatt. (2009) Control of transcriptional elongation and cotranscriptional histone modification by the yeast BUR kinase substrate Spt5. Proceedings of the National Academy of Sciences 106:17, pages 6956-6961.
Crossref
Hongfang Qiu, Cuihua Hu & Alan G. Hinnebusch. (2009) Phosphorylation of the Pol II CTD by KIN28 Enhances BUR1/BUR2 Recruitment and Ser2 CTD Phosphorylation Near Promoters. Molecular Cell 33:6, pages 752-762.
Crossref
Yinfeng Zhang, Martha L. Sikes, Ann L. Beyer & David A. Schneider. (2009) The Paf1 complex is required for efficient transcription elongation by RNA polymerase I. Proceedings of the National Academy of Sciences 106:7, pages 2153-2158.
Crossref
Nilabja Sikdar, Soma Banerjee, Han Zhang, Stephanie Smith & Kyungjae Myung. (2008) Spt2p Defines a New Transcription-Dependent Gross Chromosomal Rearrangement Pathway. PLoS Genetics 4:12, pages e1000290.
Crossref
Heather A Marton & Stephen Desiderio. (2008) The Paf1 complex promotes displacement of histones upon rapid induction of transcription by RNA polymerase II. BMC Molecular Biology 9:1.
Crossref
Pau Pascual-García, Chhabi K. Govind, Ethel Queralt, Bernardo Cuenca-Bono, Ana Llopis, Sebastián Chavez, Alan G. Hinnebusch & Susana Rodríguez-Navarro. (2008) Sus1 is recruited to coding regions and functions during transcription elongation in association with SAGA and TREX2. Genes & Development 22:20, pages 2811-2822.
Crossref
Juliet Ansel, Hélène Bottin, Camilo Rodriguez-Beltran, Christelle Damon, Muniyandi Nagarajan, Steffen Fehrmann, Jean François & Gaël Yvert. (2008) Cell-to-Cell Stochastic Variation in Gene Expression Is a Complex Genetic Trait. PLoS Genetics 4:4, pages e1000049.
Crossref
Qiye He, Luisa Battistella & Randall H. Morse. (2008) Mediator Requirement Downstream of Chromatin Remodeling during Transcriptional Activation of CHA1 in Yeast. Journal of Biological Chemistry 283:9, pages 5276-5286.
Crossref
Katherine M Nyswaner, Mary Ann Checkley, Ming Yi, Robert M Stephens & David J Garfinkel. (2008) Chromatin-Associated Genes Protect the Yeast Genome From Ty1 Insertional Mutagenesis. Genetics 178:1, pages 197-214.
Crossref
Steve G. Hershman, Qijun Chen, Julia Y. Lee, Marina L. Kozak, Peng Yue, Li-San Wang & F. Brad Johnson. (2008) Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae. Nucleic Acids Research 36:1, pages 144-156.
Crossref
Yaya Chu, Rajna Simic, Marcie H Warner, Karen M Arndt & Gregory Prelich. (2007) Regulation of histone modification and cryptic transcription by the Bur1 and Paf1 complexes. The EMBO Journal 26:22, pages 4646-4656.
Crossref
Xiaofeng Cui, Baofang Fan, James Scholz & Zhixiang Chen. (2007) Roles of Arabidopsis Cyclin-Dependent Kinase C Complexes in Cauliflower Mosaic Virus Infection, Plant Growth, and Development . The Plant Cell 19:4, pages 1388-1402.
Crossref
Bing Li, Michael Carey & Jerry L. Workman. (2007) The Role of Chromatin during Transcription. Cell 128:4, pages 707-719.
Crossref
Chhabi K. Govind, Fan Zhang, Hongfang Qiu, Kimberly Hofmeyer & Alan G. Hinnebusch. (2007) Gcn5 Promotes Acetylation, Eviction, and Methylation of Nucleosomes in Transcribed Coding Regions. Molecular Cell 25:1, pages 31-42.
Crossref
. (2006) Current awareness on yeast. Yeast 23:14-15, pages 1115-1122.
Crossref

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