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Molecular and Cellular Biology Volume 10, 1990 - Issue 2
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Cell Growth and Development

Deletion of the Kinase Insert Sequence of the Platelet-Derived Growth Factor β-Receptor Affects Receptor Kinase Activity and Signal Transduction

Ltv Severinsson1 Ludwig Institute for Cancer Research, Biomedical Center, Box 595, S-751 23Uppsala, Sweden
,
Bo Ek1 Ludwig Institute for Cancer Research, Biomedical Center, Box 595, S-751 23Uppsala, Sweden
,
Karin Mellström2 Department of Pathology, University Hospital, S-751 85Uppsala, Sweden
,
Lena Claesson-Welsh1 Ludwig Institute for Cancer Research, Biomedical Center, Box 595, S-751 23Uppsala, Sweden
&
Carl-Henrik Heldin1 Ludwig Institute for Cancer Research, Biomedical Center, Box 595, S-751 23Uppsala, Sweden
Pages 801-809 | Received 15 Sep 1989, Accepted 08 Nov 1989, Published online: 31 Mar 2023

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Saskia M. Brachmann, Claudine M. Yballe, Metello Innocenti, Jonathan A. Deane, David A. Fruman, Sheila M. Thomas & Lewis C. Cantley. (2005) Role of Phosphoinositide 3-Kinase Regulatory Isoforms in Development and Actin Rearrangement. Molecular and Cellular Biology 25:7, pages 2593-2606.
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R. Nishimura, W. Li, A. Kashishian, A. Mondino, M. Zhou, J. Cooper & J. Schlessinger. (1993) Two Signaling Molecules Share a Phosphotyrosine-Containing Binding Site in the Platelet-Derived Growth Factor Receptor. Molecular and Cellular Biology 13:11, pages 6889-6896.
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Christopher L. Carpenter, Kurt R. Auger, Brian C. Duckworth, Wei-Min Hou, Brian Schaffhausen & Lewis C. Cantley. (1993) A Tightly Associated Serine/Threonine Protein Kinase Regulates Phosphoinositide 3-Kinase Activity. Molecular and Cellular Biology 13:3, pages 1657-1665.
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Peter van der Geer & Tony Hunter. (1991) Tyrosine 706 and 807 Phosphorylation Site Mutants in the Murine Colony-Stimulating Factor-1 Receptor Are Unaffected in Their Ability To Bind or Phosphorylate Phosphatidylinositol-3 Kinase but Show Differential Defects in Their Ability To Induce Early Response Gene Transcription. Molecular and Cellular Biology 11:9, pages 4698-4709.
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Mohammad A. Heidaran, Jacalyn H. Pierce, Daniela Lombardi, Marco Ruggiero, J. Silvio Gutkind, Toshimitsu Matsui & Stuart A. Aaronson. (1991) Deletion or Substitution within the a Platelet-Derived Growth Factor Receptor Kinase Insert Domain: Effects on Functional Coupling with Intracellular Signaling Pathways. Molecular and Cellular Biology 11:1, pages 134-142.
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