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Molecular and Cellular Biology Volume 10, 1990 - Issue 6
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Cell Growth and Development

The Carboxy-Terminal Domains of erbB-2 and Epidermal Growth Factor Receptor Exert Different Regulatory Effects on Intrinsic Receptor Tyrosine Kinase Function and Transforming Activity

Pier Paolo Di Fiore1 Laboratory of Cellular and Molecular Biology, National Cancer Institute, Building 37, Room 1E24, Bethesda, Maryland20892
,
Oreste Segatto1 Laboratory of Cellular and Molecular Biology, National Cancer Institute, Building 37, Room 1E24, Bethesda, Maryland20892
,
Fulvio Lonardo1 Laboratory of Cellular and Molecular Biology, National Cancer Institute, Building 37, Room 1E24, Bethesda, Maryland20892
,
Francesca Fazioli1 Laboratory of Cellular and Molecular Biology, National Cancer Institute, Building 37, Room 1E24, Bethesda, Maryland20892
,
Jacalyn H. Pierce1 Laboratory of Cellular and Molecular Biology, National Cancer Institute, Building 37, Room 1E24, Bethesda, Maryland20892
&
Stuart A. A. Aronson1 Laboratory of Cellular and Molecular Biology, National Cancer Institute, Building 37, Room 1E24, Bethesda, Maryland20892
Pages 2749-2756 | Received 05 Sep 1989, Accepted 08 Mar 1990, Published online: 01 Apr 2023

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Jason J. Northey, Juliann Chmielecki, Elaine Ngan, Caterina Russo, Matthew G. Annis, William J. Muller & Peter M. Siegel. (2008) Signaling through ShcA Is Required for Transforming Growth Factor β- and Neu/ErbB-2-Induced Breast Cancer Cell Motility and Invasion. Molecular and Cellular Biology 28:10, pages 3162-3176.
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David Dankort, Bart Maslikowski, Neil Warner, Nubufumi Kanno, Harold Kim, Zhixiang Wang, Michael F. Moran, Robert G. Oshima, Robert D. Cardiff & William J. Muller. (2001) Grb2 and Shc Adapter Proteins Play Distinct Roles in Neu (ErbB-2)-Induced Mammary Tumorigenesis: Implications for Human Breast Cancer. Molecular and Cellular Biology 21:5, pages 1540-1551.
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Loredana Fiorentino, Chiara Pertica, Monia Fiorini, Claudio Talora, Marco Crescenzi, Loriana Castellani, Stefano Alemà, Piero Benedetti & Oreste Segatto. (2000) Inhibition of ErbB-2 Mitogenic and Transforming Activity by RALT, a Mitogen-Induced Signal Transducer Which Binds to the ErbB-2 Kinase Domain. Molecular and Cellular Biology 20:20, pages 7735-7750.
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David L. Dankort, Zhixiang Wang, Valerie Blackmore, Michael F. Moran & William J. Muller. (1997) Distinct Tyrosine Autophosphorylation Sites Negatively and Positively Modulate Neu-Mediated Transformation. Molecular and Cellular Biology 17:9, pages 5410-5425.
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Qinghua Xiong, Joseph L.-K. Chan, Cong S. Zong & Lu-Hai Wang. (1996) Two Chimeric Receptors of Epidermal Growth Factor Receptor and c-Ros That Differ in Their Transmembrane Domains Have Opposite Effects on Cell Growth. Molecular and Cellular Biology 16:4, pages 1509-1518.
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Brona Matoskova, William T. Wong, Anna Elisabetta Salcini, Pier Giuseppe Pelicci & Pier Paolo Di Fiore. (1995) Constitutive Phosphorylation of eps8 in Tumor Cell Lines: Relevance to Malignant Transformation. Molecular and Cellular Biology 15:7, pages 3805-3812.
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Paolo Fedi, Jacalyn H. Pierce, Pier Paolo di Fiore & Matthias H. Kraus. (1994) Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase Cϒ or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members. Molecular and Cellular Biology 14:1, pages 492-500.
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Francesca Fazioli, Liliana Minichiello, Brona Maťoškovā, William T. Wong & Pier Paolo Di Fiore. (1993) eps15, A Novel Tyrosine Kinase Substrate, Exhibits Transforming Activity. Molecular and Cellular Biology 13:9, pages 5814-5828.
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Oreste Segatto, Fulvio Lonardo, Daniel Wexler, Francesca Fazioli, Jacalyn H. Pierce, Donald P. Bottaro, Morris F. White & Pier Paolo Di Fiore. (1991) The Juxtamembrane Regions of the Epidermal Growth Factor Receptor and gpl85 Determine the Specificity of Signal Transduction. Molecular and Cellular Biology 11:6, pages 3191-3202.
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Eddi di Marco, Jacalyn H. Pierce, Charles L. Knicley & Pier Paolo Di Fiore. (1990) Transformation of NIH 3T3 Cells by Overexpression of the Normal Coding Sequence of the Rat neu Gene. Molecular and Cellular Biology 10:6, pages 3247-3252.
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