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Molecular and Cellular Biology Volume 11, 1991 - Issue 1
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Gene Expression

Role of the Ligand in Intracellular Receptor Function: Receptor Affinity Determines Activation In Vitro of the Latent Dioxin Receptor to a DNA-Binding Form

Scott Cuthill1 Department of Medical Nutrition, Karolinska Institute, Huddinge University HospitalF-60, Novum, S-141 86Huddinge, Sweden
,
Anna Wilhelmsson1 Department of Medical Nutrition, Karolinska Institute, Huddinge University HospitalF-60, Novum, S-141 86Huddinge, Sweden
&
Lorenz Poellinger1 Department of Medical Nutrition, Karolinska Institute, Huddinge University HospitalF-60, Novum, S-141 86Huddinge, Sweden
Pages 401-411 | Received 04 Jun 1990, Accepted 23 Oct 1990, Published online: 31 Mar 2023

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Ingemar Pongratz, Camilla Antonsson, Murray L. Whitelaw & Lorenz Poellinger. (1998) Role of the PAS Domain in Regulation of Dimerization and DNA Binding Specificity of the Dioxin Receptor. Molecular and Cellular Biology 18:7, pages 4079-4088.
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J. Craig Rowlands & Jan-Åke Gustafsson. (1997) Aryl Hydrocarbon Receptor-Mediated Signal Transduction. Critical Reviews in Toxicology 27:2, pages 109-134.
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Venkatesh Krishnan, Weston Porter, Michael Santostefano, Xiahong Wang & Stephen Safe. (1995) Molecular Mechanism of Inhibition of Estrogen-Induced Cathepsin D Gene Expression by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) in MCF-7 Cells. Molecular and Cellular Biology 15:12, pages 6710-6719.
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Camilla Antonsson, Murray L. Whitelaw, Jacqueline McGuire, Jan-Åke Gustafsson & Lorenz Poellinger. (1995) Distinct Roles of the Molecular Chaperone hsp90 in Modulating Dioxin Receptor Function via the Basic Helix-Loop-Helix and PAS Domains. Molecular and Cellular Biology 15:2, pages 756-765.
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Jacqueline McGuire, Murray L. Whitelaw, Ingemar Pongratz, Jan-Åke Gustafsson & Lorenz Poellinger. (1994) A Cellular Factor Stimulates Ligand-Dependent Release of hsp90 from the Basic Helix-Loop-Helix Dioxin Receptor. Molecular and Cellular Biology 14:4, pages 2438-2446.
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Ruth A. Pimental, Beirong Liang, Gene K. Yee, Anna Wilhelmsson, Lorenz Poellinger & K. Eric Paulson. (1993) Dioxin Receptor and C/EBP Regulate the Function of the Glutathione S-Transferase Ya Gene Xenobiotic Response Element. Molecular and Cellular Biology 13:7, pages 4365-4373.
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Murray Whitelaw, Ingemar Pongratz, Anna Wilhelmsson, Jan-Åke Gustafsson & Lorenz Poellinger. (1993) Ligand-Dependent Recruitment of the Arnt Coregulator Determines DNA Recognition by the Dioxin Receptor. Molecular and Cellular Biology 13:4, pages 2504-2514.
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Anna Berghard, Katarina Gradin, Ingemar Pongratz, Murray Whitelaw & Lorenz Poellinger. (1993) Cross-Coupling of Signal Transduction Pathways: the Dioxin Receptor Mediates Induction of Cytochrome P-450IA1 Expression via a Protein Kinase C-Dependent Mechanism. Molecular and Cellular Biology 13:1, pages 677-689.
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Eui Kutoh, Per-Erik Strömstedt & Lorenz Poellinger. (1992) Functional Interference between the Ubiquitous and Constitutive Octamer Transcription Factor 1 (OTF-1) and the Glucocorticoid Receptor by Direct Protein-Protein Interaction Involving the Homeo Subdomain of OTF-1. Molecular and Cellular Biology 12:11, pages 4960-4969.
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Janet Hapgood, Scott Cuthill, Peter Söderkvist, Anna Wilhelmsson, Ingemar Pongratz, Robert H. Tukey, Eric F. Johnson, Jan-Åke Gustafsson & Lorenz Poellinger. (1991) Liver Cells Contain Constitutive DNase I-Hypersensitive Sites at the Xenobiotic Response Elements 1 and 2 (XRE1 and -2) of the Rat Cytochrome P-4501Al Gene and a Constitutive, Nuclear XRE- Binding Factor That Is Distinct from the Dioxin Receptor. Molecular and Cellular Biology 11:9, pages 4314-4323.
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