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Transcriptional Regulation

Functional Characterization of the NF-κB p65 Transcriptional Activator and an Alternatively Spliced Derivative

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Pages 444-454 | Received 28 Aug 1991, Accepted 30 Oct 1991, Published online: 01 Apr 2023

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Chun Luo, Emmanuel Burgeon, Josephine A. Carew, Patricia G. McCaffrey, Tina M. Badalian, William S. Lane, Patrick G. Hogan & Anjana Rao. (1996) Recombinant NFAT1 (NFATp) Is Regulated by Calcineurin in T Cells and Mediates Transcription of Several Cytokine Genes. Molecular and Cellular Biology 16:7, pages 3955-3966.
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Shao-Cong Sun, John Elwood & Warner C. Greene. (1996) Both Amino- and Carboxyl-Terminal Sequences within IκBα Regulate Its Inducible Degradation. Molecular and Cellular Biology 16:3, pages 1058-1065.
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Xiangao Sun, Hiroko Shimizu & Ken-Ichi Yamamoto. (1995) Identification of a Novel p53 Promoter Element Involved in Genotoxic Stress-Inducible p53 Gene Expression. Molecular and Cellular Biology 15:8, pages 4489-4496.
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Jeffrey A. Brockman, David C. Scherer, Timothy A. McKinsey, Sarah M. Hall, Xiaoxia Qi, Wha Young Lee & Dean W. Ballard. (1995) Coupling of a Signal Response Domain in IκBα to Multiple Pathways for NF-κB Activation. Molecular and Cellular Biology 15:5, pages 2809-2818.
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Manuel S. Rodriguez, Ioannis Michalopoulos, Fernando Arenzana-Seisdedos & Ronald T. Hay. (1995) Inducible Degradation of IκBα In Vitro and In Vivo Requires the Acidic C-Terminal Domain of the Protein. Molecular and Cellular Biology 15:5, pages 2413-2419.
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Mary K. Ernst, Linda L. Dunn & Nancy R. Rice. (1995) The Pest-Like Sequence of IκBα Is Responsible for Inhibition of DNA Binding but Not for Cytoplasmic Retention of c-Rel or RelA Homodimers. Molecular and Cellular Biology 15:2, pages 872-882.
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Dimitris Thanos & Tom Maniatis. (1995) Identification of the rel Family Members Required for Virus Induction of the Human Beta Interferon Gene. Molecular and Cellular Biology 15:1, pages 152-164.
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Neil D. Perkins, Adam B. Agranoff, Erica Pascal & Gary J. Nabel. (1994) An Interaction between the DNA-Binding Domains of RelA(p65) and Sp1 Mediates Human Immunodeficiency Virus Gene Activation. Molecular and Cellular Biology 14:10, pages 6570-6583.
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Hannah Lewis, Wiweka Kaszubska, John F. Delamarter & James Whelan. (1994) Cooperativity between Two NF-κΒ Complexes, Mediated by High-Mobility-Group Protein I(Y), Is Essential for Cytokine-Induced Expression of the E-Selectin Promoter. Molecular and Cellular Biology 14:9, pages 5701-5709.
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Jose R. Perez, Kimberly A. Higgins-Sochaski, Jean-Yves Maltese & Ramaswamy Narayanan. (1994) Regulation of Adhesion and Growth of Fibrosarcoma Cells by NF-κB RelA Involves Transforming Growth Factor β. Molecular and Cellular Biology 14:8, pages 5326-5332.
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Qiang Zhang, Joseph A. Didonato, Michael Karin & Timothy W. Mckeithan. (1994) BCL3 Encodes a Nuclear Protein Which Can Alter the Subcellular Location of NF-κB Proteins. Molecular and Cellular Biology 14:6, pages 3915-3926.
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Paul A. Oeth, Graham C. N. Parry, Charles Kunsch, Pascale Nantermet, Craig A. Rosen & Nigel Mackman. (1994) Lipopolysaccharide Induction of Tissue Factor Gene Expression in Monocytic Cells Is Mediated by Binding of c-Rel/p65 Heterodimers to a κB-Like Site. Molecular and Cellular Biology 14:6, pages 3772-3781.
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David E. Gutsch, Elizabeth A. Holley-Guthrie, Qin Zhang, Bernd Stein, Michael A. Blanar, Albert S. Baldwin & Shannon C. Kenney. (1994) The bZIP Transactivator of Epstein-Barr Virus, BZLF1, Functionally and Physically Interacts with the p65 Subunit of NF-kB. Molecular and Cellular Biology 14:3, pages 1939-1948.
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Parham A. Ganchi, Shao-Cong Sun, Warner C. Greene & Dean W. Ballard. (1993) A Novel NF-κB Complex Containing p65 Homodimers: Implications for Transcriptional Control at the Level of Subunit Dimerization. Molecular and Cellular Biology 13:12, pages 7826-7835.
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Wiweka Kaszubska, Rob Hooft van Huijsduijnen, Paola Ghersa, Anne-Marie Deraemy-Schenk, Benjamin P. C. Chen, Tsonwin Hai, John F. Delamarter & James Whelan. (1993) Cyclic AMP-Independent ATF Family Members Interact with NF-κB and Function in the Activation of the E-Selectin Promoter in Response to Cytokines. Molecular and Cellular Biology 13:11, pages 7180-7190.
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Hong Bing Shu, Adam B. Agranoff, Elizabeth G. Nabel, Kwanyee Leung, Colin S. Duckett, Andrew S. Neish, Tucker Collins & Gary J. Nabel. (1993) Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-κB Subunits in Endothelial and Epithelial Cells. Molecular and Cellular Biology 13:10, pages 6283-6289.
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John Hiscott, James Marois, Jenny Garoufalis, Mario D'Addario, Anne Roulston, Ivy Kwan, Normand Pepin, Judith Lacoste, Hannah Nguyen, Giuliano Bensi & Matthew Fenton. (1993) Characterization of a Functional NF-κB Site in the Human Interleukin 1β Promoter: Evidence for a Positive Autoregulatory Loop. Molecular and Cellular Biology 13:10, pages 6231-6240.
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Charles Kunsch & Craig A. Rosen. (1993) NF-κB Subunit-Specific Regulation of the Interleukin-8 Promoter. Molecular and Cellular Biology 13:10, pages 6137-6146.
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Zbynek Kozmik, Robert Kurzbauer, Petra Dörfler & Meinrad Busslinger. (1993) Alternative Splicing of Pax-8 Gene Transcripts is Developmentally Regulated and Generates Isoforms with Different Transactivation Properties. Molecular and Cellular Biology 13:10, pages 6024-6035.
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Reinhard Buettner, Perry Kannan, Axel Imhof, Reinhard Bauer, Sun O. Yim, Rudolf Glockshuber, Michael W. Van Dyke & Michael A. Tainsky. (1993) An Alternatively Spliced mRNA from the AP-2 Gene Encodes a Negative Regulator of Transcriptional Activation by AP-2. Molecular and Cellular Biology 13:7, pages 4174-4185.
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Bernd Stein, Patricia C. Cogswell & Albert S. Baldwin$suffix/text()$suffix/text(). (1993) Functional and Physical Associations between NF-κB and C/EBP Family Members: a Rel Domain-bZIP Interaction. Molecular and Cellular Biology 13:7, pages 3964-3974.
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Timothy A. Coleman, Charles Kunsch, Maureen Maher, Steven M. Ruben & Craig A. Rosen. (1993) Acquisition of NFKB1-Selective DNA Binding by Substitution of Four Amino Acid Residues from NFKB1 into RelA. Molecular and Cellular Biology 13:7, pages 3850-3859.
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Ramaswamy Narayanan, Kimberly A. Higgins, Jose R. Perez, Timothy A. Coleman & Craig A. Rosen. (1993) Evidence for Differential Functions of the p50 and p65 Subunits of NF-κB with a Cell Adhesion Model. Molecular and Cellular Biology 13:6, pages 3802-3810.
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Amer A. Beg, Timothy S. Finco, Pascale V. Nantermet & Albert S. Baldwin$suffix/text()$suffix/text(). (1993) Tumor Necrosis Factor and Interleukin-1 Lead to Phosphorylation and Loss of IκBα: a Mechanism for NF-κB Activation. Molecular and Cellular Biology 13:6, pages 3301-3310.
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Paul A. Moore, Steven M. Ruben & Craig A. Rosen. (1993) Conservation of Transcriptional Activation Functions of the NF-κB p50 and p65 Subunits in Mammalian Cells and Saccharomyces cerevisiae. Molecular and Cellular Biology 13:3, pages 1666-1674.
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Pawel Dobrzanski, Rolf-Peter Ryseck & Rodrigo Bravo. (1993) Both N- and C-Terminal Domains of RelB Are Required for Full Transactivation: Role of the N-Terminal Leucine Zipper-Like Motif. Molecular and Cellular Biology 13:3, pages 1572-1582.
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Colin S. Duckett, Neil D. Perkins, Timothy F. Kowalik, Roland M. Schmid, Eng-Shang Huang, Albert S. Baldwin$suffix/text()$suffix/text() & Gary J. Nabel. (1993) Dimerization of NF-KB2 with RelA(p65) Regulates DNA Binding, Transcriptional Activation, and Inhibition by an IκB-α (MAD-3). Molecular and Cellular Biology 13:3, pages 1315-1322.
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Charles Kunsch, Steven M. Ruben & Craig A. Rosen. (1992) Selection of Optimal κB/Rel DNA-Binding Motifs: Interaction of Both Subunits of NF-κB with DNA Is Required for Transcriptional Activation. Molecular and Cellular Biology 12:10, pages 4412-4421.
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