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Molecular and Cellular Biology Volume 12, 1992 - Issue 2
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Cell Growth and Development

Anti-Oncogenic Activity of Signalling-Defective Epidermal Growth Factor Receptor Mutants

Norbert Redemann1 Department of Molecular Biology, Max-Planck-Institut für Biochemie, Am Klopferspitz 18A, 8033Martinsried, Germany
,
Bernhard Holzmann1 Department of Molecular Biology, Max-Planck-Institut für Biochemie, Am Klopferspitz 18A, 8033Martinsried, Germany
,
Thomas Von Rüden2 Institute of Molecular Pathology, 1030Vienna, Austria
,
Erwin F. Wagner2 Institute of Molecular Pathology, 1030Vienna, Austria
,
Joseph Schlessinger3 Department of Pharmacology, New York University Medical Center, New York, New York10016
&
Axel Ullrich1 Department of Molecular Biology, Max-Planck-Institut für Biochemie, Am Klopferspitz 18A, 8033Martinsried, Germany
Pages 491-498 | Received 21 Jun 1991, Accepted 01 Nov 1991, Published online: 01 Apr 2023

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HSIU-WEN CHAN, ANNA JENKINS, LUISA PIPOLO, ROSS D. HANNAN, WALTER G. THOMAS & NICOLA J. SMITH. (2006) Effect of Dominant-Negative Epidermal Growth Factor Receptors on Cardiomyocyte Hypertrophy. Journal of Receptors and Signal Transduction 26:5-6, pages 659-677.
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Nabeel Bardeesy, Minjung Kim, Jin Xu, Ryung-Suk Kim, Qiong Shen, Marcus W. Bosenberg, Wing H. Wong & Lynda Chin. (2005) Role of Epidermal Growth Factor Receptor Signaling in RAS-Driven Melanoma. Molecular and Cellular Biology 25:10, pages 4176-4188.
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Christine L. Burke & David F. Stern. (1998) Activation of Neu (ErbB-2) Mediated by Disulfide Bond-Induced Dimerization Reveals a Receptor Tyrosine Kinase Dimer Interface. Molecular and Cellular Biology 18:9, pages 5371-5379.
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Stephanie S. Watowich, Douglas J. Hilton & Harvey F. Lodish. (1994) Activation and Inhibition of Erythropoietin Receptor Function: Role of Receptor Dimerization. Molecular and Cellular Biology 14:6, pages 3535-3549.
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Dwayne L. Barber, John C. DeMartino, Mark O. Showers & Alan D. D'Andrea. (1994) A Dominant Negative Erythropoietin (EPO) Receptor Inhibits EPO-Dependent Growth and Blocks F-gp55-Dependent Transformation. Molecular and Cellular Biology 14:4, pages 2257-2265.
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Articles from other publishers (3)

Sylvie Rodrigues, Samir Attoub, Quang-Dé Nguyen, Erik Bruyneel, Christelle M Rodrigue, Bruce R Westley, Felicity E B May, Lars Thim, Marc Mareel, Shahin Emami & Christian Gespach. (2003) Selective abrogation of the proinvasive activity of the trefoil peptides pS2 and spasmolytic polypeptide by disruption of the EGF receptor signaling pathways in kidney and colonic cancer cells. Oncogene 22:29, pages 4488-4497.
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G Bowers, D Reardon, T Hewitt, P Dent, R B Mikkelsen, K Valerie, G Lammering, C Amir & R K Schmidt-Ullrich. (2001) The relative role of ErbB1–4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells. Oncogene 20:11, pages 1388-1397.
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Dean B Reardon, Joseph N Contessa, Ross B Mikkelsen, Kristoffer Valerie, Cyrus Amir, Paul Dent & Rupert K Schmidt-Ullrich. (1999) Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells. Oncogene 18:33, pages 4756-4766.
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