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Molecular and Cellular Biology Volume 12, 1992 - Issue 2
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Gene Expression

The Restricted Promoter Activity of the Liver Transcription Factor Hepatocyte Nuclear Factor 3β Involves a Cell-Specific Factor and Positive Autoactivation

Luca PaniDepartment of Biochemistry, University of Illinois College of Medicine, 1853 West Polk Street, Chicago, Illinois60612
,
Xiaobing QianDepartment of Biochemistry, University of Illinois College of Medicine, 1853 West Polk Street, Chicago, Illinois60612
,
Derek ClevidenceDepartment of Biochemistry, University of Illinois College of Medicine, 1853 West Polk Street, Chicago, Illinois60612
&
Robert H. CostaDepartment of Biochemistry, University of Illinois College of Medicine, 1853 West Polk Street, Chicago, Illinois60612
Pages 552-562 | Received 11 Sep 1991, Accepted 11 Nov 1991, Published online: 01 Apr 2023

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Francisco M. Rausa, Yongjun Tan & Robert H. Costa. (2003) Association between Hepatocyte Nuclear Factor 6 (HNF-6) and FoxA2 DNA Binding Domains Stimulates FoxA2 Transcriptional Activity but Inhibits HNF-6 DNA Binding. Molecular and Cellular Biology 23:2, pages 437-449.
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Francisco M. Rausa, Yongjun Tan, Heping Zhou, Kyung W. Yoo, Donna Beer Stolz, Simon C. Watkins, Roberta R. Franks, Terry G. Unterman & Robert H. Costa. (2000) Elevated Levels of Hepatocyte Nuclear Factor 3β in Mouse Hepatocytes Influence Expression of Genes Involved in Bile Acid and Glucose Homeostasis. Molecular and Cellular Biology 20:21, pages 8264-8282.
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Klaus H. Kaestner, Holger Hiemisch & Günther Schütz. (1998) Targeted Disruption of the Gene Encoding Hepatocyte Nuclear Factor 3γ Results in Reduced Transcription of Hepatocyte-Specific Genes. Molecular and Cellular Biology 18:7, pages 4245-4251.
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Uzma Samadani & Robert H. Costa. (1996) The Transcriptional Activator Hepatocyte Nuclear Factor 6 Regulates Liver Gene Expression. Molecular and Cellular Biology 16:11, pages 6273-6284.
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Luc Galarneau, Jean-François Paré, Denis Allard, Diane Hamel, Lise Lévesque, Jonathan D. Tugwood, Stephen Green & Luc Bélanger. (1996) The α1-Fetoprotein Locus Is Activated by a Nuclear Receptor of the Drosophila FTZ-F1 Family. Molecular and Cellular Biology 16:7, pages 3853-3865.
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Susan C. Power & Silvia Cereghini. (1996) Positive Regulation of the vHNFl Promoter by the Orphan Receptors COUP-TFI/Ear3 and COUP-TFII/Arp1. Molecular and Cellular Biology 16:3, pages 778-791.
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Véronique Vallet, Bénédicte Antoine, Philippe Chafey, Alain Vandewalle & Axel Kahn. (1995) Overproduction of a Truncated Hepatocyte Nuclear Factor 3 Protein Inhibits Expression of Liver-Specific Genes in Hepatoma Cells. Molecular and Cellular Biology 15:10, pages 5453-5460.
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Xiaobing Qian, Uzma Samadani, Anna Porcella & Robert H. Costa. (1995) Decreased Expression of Hepatocyte Nuclear Factor 3α during the Acute-Phase Response Influences Transthyretin Gene Transcription. Molecular and Cellular Biology 15:3, pages 1364-1376.
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Jacques Philippe, Corinne Morel & Vincent R. Prezioso. (1994) Glucagon Gene Expression Is Negatively Regulated by Hepatocyte Nuclear Factor 3β. Molecular and Cellular Biology 14:5, pages 3514-3523.
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David G. Overdier, Anna Porcella & Robert H. Costa. (1994) The DNA-Binding Specificity of the Hepatocyte Nuclear Factor 3/forkhead Domain Is Influenced by Amino-Acid Residues Adjacent to the Recognition Helix. Molecular and Cellular Biology 14:4, pages 2755-2766.
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Huei-Mei Chen & Warren S.-L. Liao. (1993) Molecular Analysis of the Differential Hepatic Expression of Rat Kininogen Family Genes. Molecular and Cellular Biology 13:11, pages 6766-6777.
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Dirk Zapp, Sigrid Bartkowski, Beatrix Holewa, Christiane Zoidl, Ludger Klein-Hitpass & Gerhart U. Ryffel. (1993) Elements and Factors Involved in Tissue-Specific and Embryonic Expression of the Liver Transcription Factor LFB1 in Xenopus laevis. Molecular and Cellular Biology 13:10, pages 6416-6426.
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David A. Jackson, Kathleen E. Rowader, Kimberly Stevens, Chengyu Jiang, Patrice Milos & Kenneth S. Zaret. (1993) Modulation of Liver-Specific Transcription by Interactions between Hepatocyte Nuclear Factor 3 and Nuclear Factor 1 Binding DNA in Close Apposition. Molecular and Cellular Biology 13:4, pages 2401-2410.
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Luca Pani, David G. Overdier, Anna Porcella, Xiaobing Qian, Eseng Lai & Robert H. Costa. (1992) Hepatocyte Nuclear Factor 3β Contains Two Transcriptional Activation Domains, One of Which Is Novel and Conserved with the Drosophila Fork Head Protein. Molecular and Cellular Biology 12:9, pages 3723-3732.
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