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Molecular and Cellular Biology Volume 12, 1992 - Issue 6
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Cell Growth and Development

Structural Requirements for Enhancement of T-Cell Responsiveness by the Lymphocyte-Specific Tyrosine Protein Kinase p56lck

Lorraine Caron1 McGill Cancer Centre, McGill University, Quebec, Canada;2 Departments of Medicine, McGill University, Quebec, Canada
,
Ninan Abraham1 McGill Cancer Centre, McGill University, Quebec, Canada;2 Departments of Medicine, McGill University, Quebec, Canada
,
Tony Pawson3 Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontano, Canada
&
André Veillette1 McGill Cancer Centre, McGill University, Quebec, Canada;2 Departments of Medicine, McGill University, Quebec, Canada;4 Biochemistry, McGill University, Quebec, Canada;5 Oncology, McGill University, Quebec, Canada;6 Division of Medical Oncology, Department of Medicine, Montreal General Hospital, Montreal, Quebec, Canada
Pages 2720-2729 | Received 18 Dec 1991, Accepted 20 Mar 1992, Published online: 31 Mar 2023

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Dominique Davidson, Marcin Bakinowski, Matthew L. Thomas, Vaclav Horejsi & André Veillette. (2003) Phosphorylation-Dependent Regulation of T-Cell Activation by PAG/Cbp, a Lipid Raft-Associated Transmembrane Adaptor. Molecular and Cellular Biology 23:6, pages 2017-2028.
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Zen-ichiro Honda, Takeshi Suzuki, Hajime Kono, Masato Okada, Tadashi Yamamoto, Chisei Ra, Yutaka Morita & Kazuhiko Yamamoto. (2000) Sequential Requirements of the N-Terminal Palmitoylation Site and SH2 Domain of Src Family Kinases in the Initiation and Progression of FcɛRI Signaling. Molecular and Cellular Biology 20:5, pages 1759-1771.
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Sho Yamasaki, Masako Takamatsu & Makio Iwashima. (1996) The Kinase, SH3, and SH2 Domains of Lck Play Critical Roles in T-Cell Activation after ZAP-70 Membrane Localization. Molecular and Cellular Biology 16:12, pages 7151-7160.
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Jean-François Cloutier, Lionel M. L. Chow & André Veillette. (1995) Requirement of the SH3 and SH2 Domains for the Inhibitory Function of Tyrosine Protein Kinase p50 in T Lymphocytes. Molecular and Cellular Biology 15:11, pages 5937-5944.
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Govindaswamy Panchamoorthy, Toru Fukazawa, Lesley Stolz, Gillian Payne, Kris Reedquist, Steven Shoelson, Zhou Songyang, Lewis Cantley, Christopher Walsh & Hamid Band. (1994) Physical and Functional Interactions between SH2 and SH3 Domains of the Src Family Protein Tyrosine Kinase p59. Molecular and Cellular Biology 14:9, pages 6372-6385.
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K. V. S. Prasad, Rosana Kapeller, Ottmar Janssen, Heinrich Repke, Jonathan S. Duke-Cohan, Lewis C. Cantley & Christopher E. Rudd. (1993) Phosphatidylinositol (PI) 3-Kinase and PI 4-Kinase Binding to the CD4-p56 Complex: the p56 SH3 Domain Binds to PI 3-Kinase but Not PI 4-Kinase. Molecular and Cellular Biology 13:12, pages 7708-7717.
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François G. Gervais, Lionel M. L. Chow, Joseph M. Lee, Philip E. Branton & André Veillette. (1993) The SH2 Domain is Required for Stable Phosphorylation of p56 at Tyrosine 505, the Negative Regulatory Site. Molecular and Cellular Biology 13:11, pages 7112-7121.
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Kunxin Luo & Bartholomew M. Sefton. (1992) Activated lek Tyrosine Protein Kinase Stimulates AntigenIndependent Interleukin-2 Production in T Cells. Molecular and Cellular Biology 12:10, pages 4724-4732.
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Articles from other publishers (5)

Paul Meraner, Václav Horejsí, Alois Wolpl, Gottfried F. Fischer, Georg Stingl & Dieter Maurer. (2007) Dendritic Cells Sensitize TCRs through Self-MHC-Mediated Src Family Kinase Activation. The Journal of Immunology 178:4, pages 2262-2271.
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Viresh P. Patel, Miriana Moran, Teresa A. Low & M. Carrie Miceli. (2001) A Molecular Framework for Two-Step T Cell Signaling: Lck Src Homology 3 Mutations Discriminate Distinctly Regulated Lipid Raft Reorganization Events. The Journal of Immunology 166:2, pages 754-764.
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Solange Nervi, Catherine Atlan-Gepner, Brigitte Kahn-Perles, Patrick Lecine, Bernard Vialettes, Jean Imbert & Philippe Naquet. (2000) Specific Deficiency of p56 lck Expression in T Lymphocytes from Type 1 Diabetic Patients . The Journal of Immunology 165:10, pages 5874-5883.
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Koubun Yasuda, Atsushi Kosugi, Fumie Hayashi, Shin-ichiroh Saitoh, Masakazu Nagafuku, Yoshiko Mori, Masato Ogata & Toshiyuki Hamaoka. (2000) Serine 6 of Lck Tyrosine Kinase: A Critical Site for Lck Myristoylation, Membrane Localization, and Function in T Lymphocytes. The Journal of Immunology 165:6, pages 3226-3231.
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Laurence Briant, Véronique Robert-Hebmann, Claire Acquaviva, Annegret Pelchen-Matthews, Mark Marsh & Christian Devaux. (1998) The Protein Tyrosine Kinase p56 lck Is Required for Triggering NF-κB Activation upon Interaction of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein gp120 with Cell Surface CD4 . Journal of Virology 72:7, pages 6207-6214.
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