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Cell Growth and Development

Reconstitution of the Raf-1-MEK-ERK Signal Transduction Pathway In Vitro

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Pages 6615-6620 | Received 14 Jun 1993, Accepted 06 Aug 1993, Published online: 31 Mar 2023

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Joaquim Egea, Carme Espinet, Rosa M. Soler, Sandra Peiró, Nativitat Rocamora & Joan X. Comella. (2000) Nerve Growth Factor Activation of the Extracellular Signal-Regulated Kinase Pathway Is Modulated by Ca2+and Calmodulin. Molecular and Cellular Biology 20:6, pages 1931-1946.
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Franz Hochholdinger, Gottfried Baier, Anto Nogalo, Birgit Bauer, Hans H. Grunicke & Florian Überall. (1999) Novel Membrane-Targeted ERK1 and ERK2 Chimeras Which Act as Dominant Negative, Isotype-Specific Mitogen-Activated Protein Kinase Inhibitors of Ras-Raf-Mediated Transcriptional Activation of c-fos in NIH 3T3 Cells. Molecular and Cellular Biology 19:12, pages 8052-8065.
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Bruce Diaz, Darlene Barnard, Adele Filson, Susan MacDonald, Alastair King & Mark Marshall. (1997) Phosphorylation of Raf-1 Serine 338-Serine 339 Is an Essential Regulatory Event for Ras-Dependent Activation and Biological Signaling. Molecular and Cellular Biology 17:8, pages 4509-4516.
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Warren G. King, Mark D. Mattaliano, Tung O. Chan, Philip N. Tsichlis & Joan S. Brugge. (1997) Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation. Molecular and Cellular Biology 17:8, pages 4406-4418.
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Masamitsu Tanaka, Ruchika Gupta & Bruce J. Mayer. (1995) Differential Inhibition of Signaling Pathways by Dominant-Negative SH2/SH3 Adapter Proteins. Molecular and Cellular Biology 15:12, pages 6829-6837.
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Catrin A. Pritchard, Michael L. Samuels, Elizabeth Bosch & Martin McMahon. (1995) Conditionally Oncogenic Forms of the A-Raf and B-Raf Protein Kinases Display Different Biological and Biochemical Properties in NIH 3T3 Cells. Molecular and Cellular Biology 15:11, pages 6430-6442.
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Andrew D. Catling, Hans-Joerg Schaeffer, Christoph W. M. Reuter, G. Rukmini Reddy & Michael J. Weber. (1995) A Proline-Rich Sequence Unique to MEK1 and MEK2 Is Required for Raf Binding and Regulates MEK Function. Molecular and Cellular Biology 15:10, pages 5214-5225.
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Drell Bottorff, Stacey Stang, Sherry Agellon & James C. Stone. (1995) RAS Signalling Is Abnormal in a c-raf1 MEK1 Double Mutant. Molecular and Cellular Biology 15:9, pages 5113-5122.
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Larry M. Karnitz, Leigh Ann Burns, Shari L. Sutor, John Blenis & Robert T. Abraham. (1995) Interleukin-2 Triggers a Novel Phosphatidylinositol 3-Kinase-Dependent MEK Activation Pathway. Molecular and Cellular Biology 15:6, pages 3049-3057.
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Dirk Büscher, Robert A. Hipskind, Stefan Krautwald, Thomas Reimann & Manuela Baccarini. (1995) Ras-Dependent and -Independent Pathways Target the Mitogen-Activated Protein Kinase Network in Macrophages. Molecular and Cellular Biology 15:1, pages 466-475.
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Kevin Pumiglia, Yu-Hua Chow, John Fabian, Deborah Morrison, Stuart Decker & Richard Jove. (1995) Raf-1 N-Terminal Sequences Necessary for Ras-Raf Interaction and Signal Transduction. Molecular and Cellular Biology 15:1, pages 398-406.
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Tomas Jelinek, Andrew D. Catling, Christoph W. M. Reuter, Shonna A. Moodie, Alan Wolfman & Michael J. Weber. (1994) RAS and RAF-1 Form a Signalling Complex with MEK-1 but Not MEK-2. Molecular and Cellular Biology 14:12, pages 8212-8218.
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Andrew X. Zhu, Yi Zhao, David E. Moller & Jeffrey S. Flier. (1994) Cloning and Characterization of p97, a Novel Human Homolog of Rat ERK-3. Molecular and Cellular Biology 14:12, pages 8202-8211.
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Shonna A. Moodie, Mark J. Paris, Walter Kolch & Alan Wolfman. (1994) Association of MEK1 with p21ras GMPPNP Is Dependent on B-Raf. Molecular and Cellular Biology 14:11, pages 7153-7162.
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Richard R. Vaillancourt, Anne M. Gardner & Gary L. Johnson. (1994) B-Raf-Dependent Regulation of the MEK-1/Mitogen-Activated Protein Kinase Pathway in PC12 Cells and Regulation by Cyclic AMP. Molecular and Cellular Biology 14:10, pages 6522-6530.
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K. A. Cadwallader, H. Paterson, S. G. Macdonald & J. F. Hancock. (1994) N-Terminally Myristoylated Ras Proteins Require Palmitoylation or a Polybasic Domain for Plasma Membrane Localization. Molecular and Cellular Biology 14:7, pages 4722-4730.
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Keishi Yamauchi & Jeffrey E. Pessin. (1994) Enhancement or Inhibition of Insulin Signaling by Insulin Receptor Substrate 1 Is Cell Context Dependent. Molecular and Cellular Biology 14:7, pages 4427-4434.
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Wayne Matten, Ira Daar & George F. Vande Woude. (1994) Protein Kinase A Acts at Multiple Points To Inhibit Xenopus Oocyte Maturation. Molecular and Cellular Biology 14:7, pages 4419-4426.
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Kazi M. Ahmed, Shaozhong Dong, Ming Fan & Jian Jian Li. (2006) Nuclear Factor-κB p65 Inhibits Mitogen-Activated Protein Kinase Signaling Pathway in Radioresistant Breast Cancer Cells. Molecular Cancer Research 4:12, pages 945-955.
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