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Cell Growth and Development

Two Signaling Molecules Share a Phosphotyrosine-Containing Binding Site in the Platelet-Derived Growth Factor Receptor

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Pages 6889-6896 | Received 26 May 1993, Accepted 27 Jul 1993, Published online: 31 Mar 2023

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Saskia M. Brachmann, Claudine M. Yballe, Metello Innocenti, Jonathan A. Deane, David A. Fruman, Sheila M. Thomas & Lewis C. Cantley. (2005) Role of Phosphoinositide 3-Kinase Regulatory Isoforms in Development and Actin Rearrangement. Molecular and Cellular Biology 25:7, pages 2593-2606.
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Lolita Banerji & Martin Sattler. (2004) Targeting mutated tyrosine kinases in the therapy of myeloid leukaemias. Expert Opinion on Therapeutic Targets 8:3, pages 221-239.
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Friedhelm Bladt, Elke Aippersbach, Sigal Gelkop, Geraldine A. Strasser, Piers Nash, Anna Tafuri, Frank B. Gertler & Tony Pawson. (2003) The Murine Nck SH2/SH3 Adaptors Are Important for the Development of Mesoderm-Derived Embryonic Structures and for Regulating the Cellular Actin Network. Molecular and Cellular Biology 23:13, pages 4586-4597.
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Christopher D. Kontos, Thomas P. Stauffer, Wen-Pin Yang, John D. York, Liwen Huang, Michael A. Blanar, Tobias Meyer & Kevin G. Peters. (1998) Tyrosine 1101 of Tie2 Is the Major Site of Association of p85 and Is Required for Activation of Phosphatidylinositol 3-Kinase and Akt. Molecular and Cellular Biology 18:7, pages 4131-4140.
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James McIlroy, Daxin Chen, Christina Wjasow, Tamar Michaeli & Jonathan M. Backer. (1997) Specific Activation of p85-p110 Phosphatidylinositol 3′-Kinase Stimulates DNA Synthesis by ras- and p70 S6 Kinase-Dependent Pathways. Molecular and Cellular Biology 17:1, pages 248-255.
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Richard A. Klinghoffer, Brian Duckworth, Mindaugas Valius, Lewis Cantley & Andrius Kazlauskas. (1996) Platelet-Derived Growth Factor-Dependent Activation of Phosphatidylinositol 3-Kinase Is Regulated by Receptor Binding of SH2-Domain-Containing Proteins Which Influence Ras Activity. Molecular and Cellular Biology 16:10, pages 5905-5914.
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Raul Mendez, Martin G. Myers$suffix/text()$suffix/text(), Morris F. White & Robert E. Rhoads. (1996) Stimulation of Protein Synthesis, Eukaryotic Translation Initiation Factor 4E Phosphorylation, and PHAS-I Phosphorylation by Insulin Requires Insulin Receptor Substrate 1 and Phosphatidylinositol 3-Kinase. Molecular and Cellular Biology 16:6, pages 2857-2864.
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Maria Grazia Borrello, Luisella Alberti, Elena Arighi, Italia Bongarzone, Carlo Battistini, Alberto Bardelli, Barbara Pasini, Claudia Piutti, Maria Grazia Rizzetti, Piera Mondellini, Maria Teresa Radice & Marco A. Pierotti. (1996) The Full Oncogenic Activity of Ret/ptc2 Depends on Tyrosine 539, a Docking Site for Phospholipase Cγ. Molecular and Cellular Biology 16:5, pages 2151-2163.
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Richard R. Vaillancourt, Lynn E. Heasley, Jeffrey Zamarripa, Brooke Storey, Mindaugas Valius, Andrius Kazlauskas & Gary L. Johnson. (1995) Mitogen-Activated Protein Kinase Activation Is Insufficient for Growth Factor Receptor-Mediated PC12 Cell Differentiation. Molecular and Cellular Biology 15:7, pages 3644-3653.
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Daniela Drummond-Barbosa, Richard R. Vaillancourt, Andrius Kazlauskas & Daniel DiMaio. (1995) Ligand-Independent Activation of the Platelet-Derived Growth Factor β Receptor: Requirements for Bovine Papillomavirus E5-Induced Mitogenic Signaling. Molecular and Cellular Biology 15:5, pages 2570-2581.
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Serge Roche, Manfred Koegl, M. Vittoria Barone, Martine F. Roussel & Sara A. Courtneidge. (1995) DNA Synthesis Induced by Some but Not All Growth Factors Requires Src Family Protein Tyrosine Kinases. Molecular and Cellular Biology 15:2, pages 1102-1109.
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Monique Yoakim, Weimin Hou, Zhou Songyang, Yuxi Liu, Lewis Cantley & Brian Schaffhausen. (1994) Genetic Analysis of a Phosphatidylinositol 3-Kinase SH2 Domain Reveals Determinants of Specificity. Molecular and Cellular Biology 14:9, pages 5929-5938.
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Steve Dobrowolski, Marian Harter & Dennis W. Stacey. (1994) Cellular ras Activity Is Required for Passage through Multiple Points of the G0/G1 Phase in BALB/c 3T3 Cells. Molecular and Cellular Biology 14:8, pages 5441-5449.
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A. G. Batzer, D. Rotin, J. M. Urena, E. Y. Skolnik & J. Schlessinger. (1994) Hierarchy of Binding Sites for Grb2 and Shc on the Epidermal Growth Factor Receptor. Molecular and Cellular Biology 14:8, pages 5192-5201.
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Z. Songyang, S. E. Shoelson, J. McGlade, P. Olivier, T. Pawson, X. R. Bustelo, M. Barbacid, H. Sabe, H. Hanafusa, T. Yi, R. Ren, D. Baltimore, S. Ratnofsky, R. A. Feldman & L. C. Cantley. (1994) Specific Motifs Recognized by the SH2 Domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Molecular and Cellular Biology 14:4, pages 2777-2785.
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Patrick Hu & Joseph Schlessinger. (1994) Direct Association of p110β Phosphatidylinositol 3-kinase with p85 Is Mediated by an N-Terminal Fragment of p110β. Molecular and Cellular Biology 14:4, pages 2577-2583.
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Wei Li, Riko Nishimura, Adam Kashishian, Andreas G. Batzer, William J. H. Kim, Jonathan A. Cooper & Joseph Schlessinger. (1994) A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase. Molecular and Cellular Biology 14:1, pages 509-517.
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Articles from other publishers (4)

Angika Basant & Michael Way. (2022) The relative binding position of Nck and Grb2 adaptors impacts actin-based motility of Vaccinia virus. eLife 11.
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Tamara Utermark, Brian S. Schaffhausen, Thomas M. Roberts & Jean J. Zhao. (2007) The p110α Isoform of Phosphatidylinositol 3-Kinase Is Essential for Polyomavirus Middle T Antigen-Mediated Transformation. Journal of Virology 81:13, pages 7069-7076.
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Blanca Scheijen & James D Griffin. (2002) Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease. Oncogene 21:21, pages 3314-3333.
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Shigeto Yoshii, Masamitsu Tanaka, Yoshirou Otsuki, Dong-Yu Wang, Rong-Jun Guo, Yue Zhu, Ririko Takeda, Hiroyuki Hanai, Eizo Kaneko & Haruhiko Sugimura. (1999) αPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase. Oncogene 18:41, pages 5680-5690.
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