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Transcriptional Regulation

A Nuclear Factor for Interleukin-6 Expression (NF-IL6) and the Glucocorticoid Receptor Synergistically Activate Transcription of the Rat α1-Acid Glycoprotein Gene via Direct Protein-Protein Interaction

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Pages 1854-1862 | Received 17 Aug 1992, Accepted 14 Dec 1992, Published online: 31 Mar 2023

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Puneet Dhawan, Xiaorong Peng, Amelia L. M. Sutton, Paul N. MacDonald, Colleen M. Croniger, Christian Trautwein, Michael Centrella, Thomas L. McCarthy & Sylvia Christakos. (2005) Functional Cooperation between CCAAT/Enhancer-Binding Proteins and the Vitamin D Receptor in Regulation of 25-Hydroxyvitamin D3 24-Hydroxylase. Molecular and Cellular Biology 25:1, pages 472-487.
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Klaus Dinkel, William O Ogle & Robert M Sapolsky. (2002) Glucocorticoids and Central Nervous System Inflammation. Journal of Neurovirology 8:6, pages 513-528.
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Selena Kim, Pei-Lin Mao, Mark Gagliardi & Pierre-André Bédard. (1999) C/EBPβ (NF-M) Is Essential for Activation of the p20K Lipocalin Gene in Growth-Arrested Chicken Embryo Fibroblasts. Molecular and Cellular Biology 19:8, pages 5718-5731.
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M. W. LINDER, K. C. FALKNER, G. SRINIVASAN, R. N. HINES & R. A. PROUGH. (1999) ROLE OF CANONICAL GLUCOCORTICOID RESPONSIVE ELEMENTS IN MODULATING EXPRESSION OF GENES REGULATED BY THE ARYLHYDROCARBON RECEPTOR*. Drug Metabolism Reviews 31:1, pages 247-271.
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Vincent M. Christoffels, Thierry Grange, Klaus H. Kaestner, Timothy J. Cole, Gretchen J. Darlington, Colleen M. Croniger & Wouter H. Lamers. (1998) Glucocorticoid Receptor, C/EBP, HNF3, and Protein Kinase A Coordinately Activate the Glucocorticoid Response Unit of the Carbamoylphosphate Synthetase I Gene. Molecular and Cellular Biology 18:11, pages 6305-6315.
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Ching-Jin Chang, Ya-Ling Chen & Sheng-Chung Lee. (1998) Coactivator TIF1β Interacts with Transcription Factor C/EBPβ and Glucocorticoid Receptor To Induce α1-Acid Glycoprotein Gene Expression. Molecular and Cellular Biology 18:10, pages 5880-5887.
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Gratien G. Préfontaine, Madeleine E. Lemieux, Ward Giffin, Caroline Schild-Poulter, Louise Pope, Eric LaCasse, Peter Walker & Robert J. G. Haché. (1998) Recruitment of Octamer Transcription Factors to DNA by Glucocorticoid Receptor. Molecular and Cellular Biology 18:6, pages 3416-3430.
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Alexander Zagariya, Shubhangee Mungre, Rosa Lovis, Michael Birrer, Scott Ness, Bayar Thimmapaya & Richard Pope. (1998) Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun. Molecular and Cellular Biology 18:5, pages 2815-2824.
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Keiichi Tanaka, Norio Itoh, Kyong-Son Min & Norio Muto. (1998) Toxicological Significances of Metallothionein: Induction by Inflammation. Journal of Toxicology: Toxin Reviews 17:1, pages 57-71.
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Jyoti N. Athanikar, Hugo B. Sanchez & Timothy F. Osborne. (1997) Promoter Selective Transcriptional Synergy Mediated by Sterol Regulatory Element Binding Protein and Sp1: a Critical Role for the Btd Domain of Sp1. Molecular and Cellular Biology 17:9, pages 5193-5200.
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Alexey M. Chumakov, Isabelle Grillier, Ekaterina Chumakova, Doris Chih, James Slater & H. Phillip Koeffler. (1997) Cloning of the Novel Human Myeloid-Cell-Specific C/EBP-ε Transcription Factor. Molecular and Cellular Biology 17:3, pages 1375-1386.
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Luo-Hua Miau, Ching-Jin Chang, Wen-Hai Tsai & Sheng-Chung Lee. (1997) Identification and Characterization of a Nucleolar Phosphoprotein, Nopp140, as a Transcription Factor. Molecular and Cellular Biology 17:1, pages 230-239.
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Ross A. Ramos, Yukihiro Nishio, Anita C. Maiyar, Kay E. Simon, Cheryl C. Ridder, Ying Ge & Gary L. Firestone. (1996) Glucocorticoid-Stimulated CCAAT/Enhancer-Binding Protein α Expression Is Required for Steroid-Induced G1 Cell Cycle Arrest of Minimal-Deviation Rat Hepatoma Cells. Molecular and Cellular Biology 16:10, pages 5288-5301.
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R. R. Schumann, C. J. Kirschning, A. Unbehaun, H. Aberle, H.-P. Knopf, N. Lamping, R. J. Ulevitch & F. Herrmann. (1996) The Lipopolysaccharide-Binding Protein Is a Secretory Class 1 Acute-Phase Protein Whose Gene Is Transcriptionally Activated by APRF/STAT-3 and Other Cytokine-Inducible Nuclear Proteins. Molecular and Cellular Biology 16:7, pages 3490-3503.
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Sigrun Mink, Ulrike Kerber & Karl-Heinz Klempnauer. (1996) Interaction of C/EBPβ and v-Myb Is Required for Synergistic Activation of the mim-1 Gene. Molecular and Cellular Biology 16:4, pages 1316-1325.
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Susanne Heiland & Rolf Knippers. (1995) The Human Topoisomerase I Gene Promoter Is Regulated by NF-IL6. Molecular and Cellular Biology 15:12, pages 6623-6631.
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Bernd Stein & Maria X. Yang. (1995) Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ. Molecular and Cellular Biology 15:9, pages 4971-4979.
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Lidija Klampfer, Tae Ho Lee, Wei Hsu, Jan Vilček & Selina Chen-Kiang. (1994) NF-IL6 and AP-1 Cooperatively Modulate the Activation of the TSG-6 Gene by Tumor Necrosis Factor Alpha and Interleukin-1. Molecular and Cellular Biology 14:10, pages 6561-6569.
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Igor C. Oliveira, Naofumi Mukaida, Kouji Matsushima & Jan Vilcek. (1994) Transcriptional Inhibition of the Interleukin-8 Gene by Interferon Is Mediated by the NF-κB Site. Molecular and Cellular Biology 14:8, pages 5300-5308.
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Rosalie C. Sears & Linda Sealy. (1994) Multiple Forms of C/EBPβ Bind the EFII Enhancer Sequence in the Rous Sarcoma Virus Long Terminal Repeat. Molecular and Cellular Biology 14:7, pages 4855-4871.
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Jianyi H. Huang & Warren S.-L. Liao. (1994) Induction of the Mouse Serum Amyloid A3 Gene by Cytokines Requires both C/EBP Family Proteins and a Novel Constitutive Nuclear Factor. Molecular and Cellular Biology 14:7, pages 4475-4484.
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Martin Lotz. (1993) Interleukin-6. Cancer Investigation 11:6, pages 732-742.
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Articles from other publishers (9)

Meghan E. Pennini, Yi Liu, Jianqi Yang, Colleen M. Croniger, W. Henry Boom & Clifford V. Harding. (2007) CCAAT/Enhancer-Binding Protein β and δ Binding to CIITA Promoters Is Associated with the Inhibition of CIITA Expression in Response to Mycobacterium tuberculosis 19-kDa Lipoprotein . The Journal of Immunology 179:10, pages 6910-6918.
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Takayuki Hattori, Nobumichi Ohoka, Yasumichi Inoue, Hidetoshi Hayashi & Kikuo Onozaki. (2003) C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer. Oncogene 22:9, pages 1273-1280.
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Vladimir Hurgin, Daniela Novick & Menachem Rubinstein. (2002) The promoter of IL-18 binding protein: Activation by an IFN-γ-induced complex of IFN regulatory factor 1 and CCAAT/enhancer binding protein β. Proceedings of the National Academy of Sciences 99:26, pages 16957-16962.
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Ellora Sen, Jennifer L. Bromberg-White & Craig Meyers. (2002) Genetic Analysis of cis Regulatory Elements within the 5′ Region of the Human Papillomavirus Type 31 Upstream Regulatory Region during Different Stages of the Viral Life Cycle . Journal of Virology 76:10, pages 4798-4809.
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Margherita Rosati, Antonio Valentin, Daniel J. Patenaude & George N. Pavlakis. (2001) CCAAT-Enhancer-Binding Protein β (C/EBPβ) Activates CCR5 Promoter: Increased C/EBPβ and CCR5 in T Lymphocytes from HIV-1-Infected Individuals. The Journal of Immunology 167:3, pages 1654-1662.
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Thierry Grange, Lucia Cappabianca, Michèle Flavin, Habib Sassi & Hélène Thomassin. (2001) In vivo analysis of the model tyrosine aminotransferase gene reveals multiple sequential steps in glucocorticoid receptor action. Oncogene 20:24, pages 3028-3038.
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Peter Herrlich. (2001) Cross-talk between glucocorticoid receptor and AP-1. Oncogene 20:19, pages 2465-2475.
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Chao-Kuen Lai & Ling-Pai Ting. (1999) Transcriptional Repression of Human Hepatitis B Virus Genes by a bZIP Family Member, E4BP4. Journal of Virology 73:4, pages 3197-3209.
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Tobias Bauknecht & Yang Shi. (1998) Overexpression of C/EBPβ Represses Human Papillomavirus Type 18 Upstream Regulatory Region Activity in HeLa Cells by Interfering with the Binding of TATA-Binding Protein. Journal of Virology 72:3, pages 2113-2124.
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