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Cell Growth and Development

The α-Mating Type Locus of Cryptococcus neoformans Contains a Peptide Pheromone Gene

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Pages 1962-1970 | Received 25 Aug 1992, Accepted 18 Dec 1992, Published online: 31 Mar 2023

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Read on this site (6)

Ping Wang, John R. Perfect & Joseph Heitman. (2000) The G-Protein β Subunit GPB1 Is Required for Mating and Haploid Fruiting in Cryptococcus neoformans. Molecular and Cellular Biology 20:1, pages 352-362.
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M. Cristina Cruz, Lora M. Cavallo, Jenifer M. Görlach, Gary Cox, John R. Perfect, Maria E. Cardenas & Joseph Heitman. (1999) Rapamycin Antifungal Action Is Mediated via Conserved Complexes with FKBP12 and TOR Kinase Homologs in Cryptococcus neoformans. Molecular and Cellular Biology 19:6, pages 4101-4112.
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Lei Zhang, Rudeina A. Baasiri & Neal K. Van Alfen. (1998) Viral Repression of Fungal Pheromone Precursor Gene Expression. Molecular and Cellular Biology 18:2, pages 953-959.
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K.J. Kwon-Chung, T. Pfeiffer, Y.C. Chang, B.L. Wickes, D. Mitchell & J.J. Stern. (1994) Molecular biology of Cryptococcus neoformans and therapy of cryptococcosis. Journal of Medical and Veterinary Mycology 32:sup1, pages 407-415.
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H. Torres-Guererro & J.C. Edman. (1994) Melanin-deficient mutants of Cryptococcus neoformans. Journal of Medical and Veterinary Mycology 32:4, pages 303-313.
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Lei Zhang, Alice C. L. Churchill, Pam Kazmierczak, Dae-Hyuk Kim & Neal K. Van Alfen. (1993) Hypovirulence-Associated Traits Induced by a Mycovirus of Cryphonectria parasitica are Mimicked by Targeted Inactivation of a Host Gene. Molecular and Cellular Biology 13:12, pages 7782-7792.
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Articles from other publishers (32)

Marco A. Coelho, Guus Bakkeren, Sheng Sun, Michael E. Hood & Tatiana Giraud. (2017) Fungal Sex: The Basidiomycota. Microbiology Spectrum 5:3.
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Susan Michaelis & Jemima Barrowman. (2012) Biogenesis of the Saccharomyces cerevisiae Pheromone a -Factor, from Yeast Mating to Human Disease . Microbiology and Molecular Biology Reviews 76:3, pages 626-651.
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Zhongming Li, Jiannan Bi, Jiao Yang, Jiao Pan, Zhixiong Sun & Xudong Zhu. (2012) Requirement of a Tsp2-Type Tetraspanin for Laccase Repression and Stress Resistance in the Basidiomycete Cryptococcus neoformans. Applied and Environmental Microbiology 78:1, pages 21-27.
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Soo Chan Lee, Min Ni, Wenjun Li, Cecelia Shertz & Joseph Heitman. (2010) The Evolution of Sex: a Perspective from the Fungal Kingdom. Microbiology and Molecular Biology Reviews 74:2, pages 298-340.
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Michael R. Botts, Steven S. Giles, Marcellene A. Gates, Thomas R. Kozel & Christina M. Hull. (2009) Isolation and Characterization of Cryptococcus neoformans Spores Reveal a Critical Role for Capsule Biosynthesis Genes in Spore Biogenesis . Eukaryotic Cell 8:4, pages 595-605.
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Xiaorong Lin, Kirsten Nielsen, Sweta Patel & Joseph Heitman. (2008) Impact of Mating Type, Serotype, and Ploidy on the Virulence of Cryptococcus neoformans . Infection and Immunity 76:7, pages 2923-2938.
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Kirsten Nielsen, Anna L. De Obaldia & Joseph Heitman. (2007) Cryptococcus neoformans Mates on Pigeon Guano: Implications for the Realized Ecological Niche and Globalization . Eukaryotic Cell 6:6, pages 949-959.
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Julie K. Hicks & Joseph Heitman. (2007) Divergence of Protein Kinase A Catalytic Subunits in Cryptococcus neoformans and Cryptococcus gattii Illustrates Evolutionary Reconfiguration of a Signaling Cascade . Eukaryotic Cell 6:3, pages 413-420.
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Kari L. Cramer, Quincy D. Gerrald, Connie B. Nichols, Michael S. Price & J. Andrew Alspaugh. (2006) Transcription Factor Nrg1 Mediates Capsule Formation, Stress Response, and Pathogenesis in Cryptococcus neoformans . Eukaryotic Cell 5:7, pages 1147-1156.
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Sarah E. Kidd, Hong Guo, Karen H. Bartlett, Jianping Xu & James W. Kronstad. (2005) Comparative Gene Genealogies Indicate that Two Clonal Lineages of Cryptococcus gattii in British Columbia ResembleStrains from Other Geographical Areas . Eukaryotic Cell 4:10, pages 1629-1638.
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Peter R. Kraus, Connie B. Nichols & Joseph Heitman. (2005) Calcium- and Calcineurin-Independent Roles for Calmodulin in Cryptococcus neoformans Morphogenesis and High-Temperature Growth . Eukaryotic Cell 4:6, pages 1079-1087.
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Marcelo A. Vallim, Connie B. Nichols, Larissa Fernandes, Kari L. Cramer & J. Andrew Alspaugh. (2005) A Rac Homolog Functions Downstream of Ras1 To Control Hyphal Differentiation and High-Temperature Growth in the Pathogenic Fungus Cryptococcus neoformans . Eukaryotic Cell 4:6, pages 1066-1078.
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Yen-Ping Hsueh & Wei-Chiang Shen. (2005) A Homolog of Ste6, the a -Factor Transporter in Saccharomyces cerevisiae , Is Required for Mating but Not for Monokaryotic Fruiting in Cryptococcus neoformans . Eukaryotic Cell 4:1, pages 147-155.
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Yong-Sun Bahn, Julie K. Hicks, Steven S. Giles, Gary M. Cox & Joseph Heitman. (2004) Adenylyl Cyclase-Associated Protein Aca1 Regulates Virulence and Differentiation of Cryptococcus neoformans via the Cyclic AMP-Protein Kinase A Cascade . Eukaryotic Cell 3:6, pages 1476-1491.
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Ping Wang, Jim Cutler, Jill King & Daniel Palmer. (2004) Mutation of the Regulator of G Protein Signaling Crg1 Increases Virulence in Cryptococcus neoformans . Eukaryotic Cell 3:4, pages 1028-1035.
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Julie K. Hicks, Cletus A. D'Souza, Gary M. Cox & Joseph Heitman. (2004) Cyclic AMP-Dependent Protein Kinase Catalytic Subunits Have Divergent Roles in Virulence Factor Production in Two Varieties of the Fungal Pathogen Cryptococcus neoformans . Eukaryotic Cell 3:1, pages 14-26.
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Yun C. Chang, Georgina F. Miller & K. J. Kwon-Chung. (2003) Importance of a Developmentally Regulated Pheromone Receptor of Cryptococcus neoformans for Virulence . Infection and Immunity 71:9, pages 4953-4960.
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Hyojeong Kim, Robert L. Metzenberg & Mary Anne Nelson. (2002) Multiple Functions of mfa-1 , a Putative Pheromone Precursor Gene of Neurospora crassa . Eukaryotic Cell 1:6, pages 987-999.
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Klaus B. Lengeler, Deborah S. Fox, James A. Fraser, Andria Allen, Keri Forrester, Fred S. Dietrich & Joseph Heitman. (2002) Mating-Type Locus of Cryptococcus neoformans : a Step in the Evolution of Sex Chromosomes . Eukaryotic Cell 1:5, pages 704-718.
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Vishnu Chaturvedi, Jinjiang Fan, Birgit Stein, Melissa J. Behr, William A. Samsonoff, Brian L. Wickes & Sudha Chaturvedi. (2002) Molecular Genetic Analyses of Mating Pheromones Reveal Intervariety Mating or Hybridization in Cryptococcus neoformans . Infection and Immunity 70:9, pages 5225-5235.
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Seyung Chung, Marvin Karos, Yun C. Chang, Jan Lukszo, Brian L. Wickes & Kyung J. Kwon-Chung. (2002) Molecular Analysis of CPR α, a MAT α-Specific Pheromone Receptor Gene of Cryptococcus neoformans . Eukaryotic Cell 1:3, pages 432-439.
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Wei-Chiang Shen, Robert C. Davidson, Gary M. Cox & Joseph Heitman. (2002) Pheromones Stimulate Mating and Differentiation via Paracrine and Autocrine Signaling in Cryptococcus neoformans . Eukaryotic Cell 1:3, pages 366-377.
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Ping Wang, Connie B. Nichols, Klaus B. Lengeler, Maria E. Cardenas, Gary M. Cox, John R. Perfect & Joseph Heitman. (2002) Mating-Type-Specific and Nonspecific PAK Kinases Play Shared and Divergent Roles in Cryptococcus neoformans . Eukaryotic Cell 1:2, pages 257-272.
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Zhun Yan, Xiaogang Li & Jianping Xu. (2002) Geographic Distribution of Mating Type Alleles of Cryptococcus neoformans in Four Areas of the United States . Journal of Clinical Microbiology 40:3, pages 965-972.
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M. Cristina Cruz, Alan L. Goldstein, Jill Blankenship, Maurizio Del Poeta, John R. PerfectJohn H. McCusker, Youssef L. Bennani, Maria E. Cardenas & Joseph Heitman. (2001) Rapamycin and Less Immunosuppressive Analogs Are Toxic to Candida albicans and Cryptococcus neoformans via FKBP12-Dependent Inhibition of TOR . Antimicrobial Agents and Chemotherapy 45:11, pages 3162-3170.
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Klaus B. Lengeler, Robert C. Davidson, Cletus D'souza, Toshiaki Harashima, Wei-Chiang Shen, Ping Wang, Xuewen Pan, Michael Waugh & Joseph Heitman. (2000) Signal Transduction Cascades Regulating Fungal Development and Virulence. Microbiology and Molecular Biology Reviews 64:4, pages 746-785.
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M. Karos, Y. C. Chang, C. M. McClelland, D. L. Clarke, J. Fu, B. L. Wickes & K. J. Kwon-Chung. (2000) Mapping of the Cryptococcus neoformans MAT α Locus: Presence of Mating Type-Specific Mitogen-Activated Protein Kinase Cascade Homologs . Journal of Bacteriology 182:21, pages 6222-6227.
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Sudha Chaturvedi, Birgit Rodeghier, Jinjiang Fan, Carol M. McClelland, Brian L. Wickes & Vishnu Chaturvedi. (2000) Direct PCR of Cryptococcus neoformans MAT α and MAT a Pheromones To Determine Mating Type, Ploidy, and Variety: a Tool for Epidemiological and Molecular Pathogenesis Studies . Journal of Clinical Microbiology 38:5, pages 2007-2009.
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Maurizio Del Poeta, M. Cristina Cruz, Maria E. Cardenas, John R. Perfect & Joseph Heitman. (2000) Synergistic Antifungal Activities of Bafilomycin A 1 , Fluconazole, and the Pneumocandin MK-0991/Caspofungin Acetate (L-743,873) with Calcineurin Inhibitors FK506 and L-685,818 against Cryptococcus neoformans . Antimicrobial Agents and Chemotherapy 44:3, pages 739-746.
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C. L. Halliday, T. Bui, M. Krockenberger, R. Malik, D. H. Ellis & D. A. Carter. (1999) Presence of α and a Mating Types in Environmental and Clinical Collections of Cryptococcus neoformans var. gattii Strains from Australia . Journal of Clinical Microbiology 37:9, pages 2920-2926.
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Maurizio del Poeta, Dena L. Toffaletti, Thomas H. Rude, Sara D. Sparks, Joseph HeitmanJohn R. Perfect. (1999) Cryptococcus neoformans Differential Gene Expression Detected In Vitro and In Vivo with Green Fluorescent Protein . Infection and Immunity 67:4, pages 1812-1820.
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Lorna A. Casselton & Natalie S. Olesnicky. (1998) Molecular Genetics of Mating Recognition in Basidiomycete Fungi. Microbiology and Molecular Biology Reviews 62:1, pages 55-70.
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