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Cell Growth and Development

Bcl-2 Blocks p53-Dependent Apoptosis

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Pages 2556-2563 | Received 16 Nov 1993, Accepted 06 Jan 1994, Published online: 30 Mar 2023

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Francesca Prignano, Federica Ricceri, Paolo Bonan, Giovanni Cannarozzo & Piero Campolmi. (2012) Induction of apoptosis by fractional CO2 laser treatment. Journal of Cosmetic and Laser Therapy 14:6, pages 267-271.
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Jenny S. L. Ho, Weili Ma, Daniel Y. L. Mao & Samuel Benchimol. (2005) p53-Dependent Transcriptional Repression of c-myc Is Required for G1 Cell Cycle Arrest. Molecular and Cellular Biology 25:17, pages 7423-7431.
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Dali Yin, Norihiko Tamaki, Andrew D. Parent & John H. Zhang. (2005) Insulin-like growth factor-I decreased etoposide-induced apoptosis in glioma cells by increasing bcl-2 expression and decreasing CPP32 activity. Neurological Research 27:1, pages 27-35.
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Gary M. Kasof, Lakshmi Goyal & Eileen White. (1999) Btf, a Novel Death-Promoting Transcriptional Repressor That Interacts with Bcl-2-Related Proteins. Molecular and Cellular Biology 19:6, pages 4390-4404.
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Jeonghoon Han, Hershel D. Wallen, Gabriel Nuñez & Eileen White. (1998) E1B 19,000-Molecular-Weight Protein Interacts with and Inhibits CED-4-Dependent, FLICE-Mediated Apoptosis. Molecular and Cellular Biology 18:10, pages 6052-6062.
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Raymond H. See & Yang Shi. (1998) Adenovirus E1B 19,000-Molecular-Weight Protein Activates c-Jun N-Terminal Kinase and c-Jun-Mediated Transcription. Molecular and Cellular Biology 18:7, pages 4012-4022.
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Qingjian Wang, Gerard P. Zambetti & D. Parker Suttle. (1997) Inhibition of DNA Topoisomerase IIα Gene Expression by the p53 Tumor Suppressor. Molecular and Cellular Biology 17:1, pages 389-397.
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Jeonghoon Han, Peter Sabbatini & Eileen White. (1996) Induction of Apoptosis by Human Nbk/Bik, a BH3-Containing Protein That Interacts with E1B 19K. Molecular and Cellular Biology 16:10, pages 5857-5864.
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P. Friedlander, Y. Haupt, C. Prives & M. Oren. (1996) A Mutant p53 That Discriminates between p53-Responsive Genes Cannot Induce Apoptosis. Molecular and Cellular Biology 16:9, pages 4961-4971.
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Jiandong Chen, Xiangwei Wu, Jiayuh Lin & Arnold J. Levine. (1996) mdm-2 Inhibits the G1 Arrest and Apoptosis Functions of the p53 Tumor Suppressor Protein. Molecular and Cellular Biology 16:5, pages 2445-2452.
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Wilma T. Steegenga, Theo Van Laar, Nicole Riteco, Angelo Mandarino, Avi Shvarts, Alex J. Van Der Eb & A. G. Jochemsen. (1996) Adenovirus E1A Proteins Inhibit Activation of Transcription by p53. Molecular and Cellular Biology 16:5, pages 2101-2109.
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Gloria A. Preston, Tracy T. Lyon, Yuxin Yin, Jason E. Lang, Gregory Solomon, Lois Annab, Dayalan G. Srinivasan, David A. Alcorta & J. Carl Barrett. (1996) Induction of Apoptosis by c-Fos Protein. Molecular and Cellular Biology 16:1, pages 211-218.
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Yunping Lin & Sam Benchimol. (1995) Cytokines Inhibit p53-Mediated Apoptosis but Not p53-Mediated G1 Arrest. Molecular and Cellular Biology 15:11, pages 6045-6054.
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Huey-Jen L. Lin, Valerie Eviner, George C. Prendergast & Eileen White. (1995) Activated H-ras Rescues E1A-Induced Apoptosis and Cooperates with E1A To Overcome p53-Dependent Growth Arrest. Molecular and Cellular Biology 15:8, pages 4536-4544.
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Peter Sabbatini, Shiun-Kwei Chiou, Lakshmi Rao & Eileen White. (1995) Modulation of p53-Mediated Transcriptional Repression and Apoptosis by the Adenovirus E1B 19K Protein. Molecular and Cellular Biology 15:2, pages 1060-1070.
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Elizabeth W. Newcomb. (1995) P53 Gene Mutations in Lymphoid Diseases and Their Possible Relevance to Drug Resistance. Leukemia & Lymphoma 17:3-4, pages 211-221.
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Pan Zhang, Zi‐Yan Liu, Dan Yu, Cui‐Xian Xu, Yan Hu, Ya‐Ping Liang, Jie Jin & Ming Li. (2022) Microplitis bicoloratus parasitism promotes cyclophilin D‐p53 interaction to induce apoptosis of hemocytes in Spodoptera litura . Archives of Insect Biochemistry and Physiology 112:2.
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Kurt Degenhardt & Eileen White. (2006) A Mouse Model System to Genetically Dissect the Molecular Mechanisms Regulating Tumorigenesis. Clinical Cancer Research 12:18, pages 5296-5304.
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Bruce J. Shenker, Donald R. Demuth & Ali Zekavat. (2006) Exposure of Lymphocytes to High Doses of Actinobacillus actinomycetemcomitans Cytolethal Distending Toxin Induces Rapid Onset of Apoptosis-Mediated DNA Fragmentation . Infection and Immunity 74:4, pages 2080-2092.
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Suzanne Cory, David C S Huang & Jerry M Adams. (2003) The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22:53, pages 8590-8607.
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Stefan Heinrichs & Wolfgang Deppert. (2003) Apoptosis or growth arrest: modulation of the cellular response to p53 by proliferative signals. Oncogene 22:4, pages 555-571.
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Holly Henry, Anju Thomas, Yan Shen & Eileen White. (2002) Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death. Oncogene 21:5, pages 748-760.
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Nicole Baptiste, Philip Friedlander, Xinbin Chen & Carol Prives. (2002) The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells. Oncogene 21:1, pages 9-21.
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Eileen White. (2001) Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus. Oncogene 20:54, pages 7836-7846.
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Anju Thomas, Theresa Giesler & Eileen White. (2000) p53 mediates Bcl-2 phosphorylation and apoptosis via activation of the Cdc42/JNK1 pathway. Oncogene 19:46, pages 5259-5269.
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Damian BS Yap, Jung-Kuang Hsieh, Florence SG Chan & Xin Lu. (1999) mdm2: a bridge over the two tumour suppressors, p53 and Rb. Oncogene 18:53, pages 7681-7689.
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C Trautwein, M Will, S Kubicka, T Rakemann, P Flemming & M P Manns. (1999) 2-Acetaminofluorene blocks cell cycle progression after hepatectomy by p21 induction and lack of Cyclin E expression. Oncogene 18:47, pages 6443-6453.
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Ronit Vogt Sionov & Ygal Haupt. (1999) The cellular response to p53: the decision between life and death. Oncogene 18:45, pages 6145-6157.
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Mauricio Rojas, Martin Olivier, Philippe Gros, Luis F. Barrera & Luis F. García. (1999) TNF-α and IL-10 Modulate the Induction of Apoptosis by Virulent Mycobacterium tuberculosis in Murine Macrophages . The Journal of Immunology 162:10, pages 6122-6131.
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Qimin Zhan, Udo Kontny, Maite Iglesias, Isaac Alamo Jr, Kelly Yu, M Christine Hollander, Craig D Woodworth & Albert J Fornace Jr. (1999) Inhibitory effect of Bcl-2 on p53-mediated transactivation following genotoxic stress. Oncogene 18:2, pages 297-304.
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Stanley Moffatt, Nobuo Yaegashi, Kohtaro Tada, Nobuyuki Tanaka & Kazuo Sugamura. (1998) Human Parvovirus B19 Nonstructural (NS1) Protein Induces Apoptosis in Erythroid Lineage Cells. Journal of Virology 72:4, pages 3018-3028.
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Bret A. Wing, Robert A. Johnson & Eng-Shang Huang. (1998) Identification of Positive and Negative Regulatory Regions Involved in Regulating Expression of the Human Cytomegalovirus UL94 Late Promoter: Role of IE2-86 and Cellular p53 in Mediating Negative Regulatory Function. Journal of Virology 72:3, pages 1814-1825.
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