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Gene Expression

Presence of Negative and Positive cis-Acting RNA Splicing Elements within and Flanking the First tat Coding Exon of Human Immunodeficiency Virus Type 1

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Pages 3960-3970 | Received 04 Jan 1994, Accepted 17 Mar 1994, Published online: 30 Mar 2023

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Read on this site (16)

Jeffrey K. Domsic, Yibin Wang, Akila Mayeda, Adrian R. Krainer & C. Martin Stoltzfus. (2003) Human Immunodeficiency Virus Type 1 hnRNP A/B-Dependent Exonic Splicing Silencer ESSV Antagonizes Binding of U2AF65 to Viral Polypyrimidine Tracts. Molecular and Cellular Biology 23:23, pages 8762-8772.
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Martin J. Simard & Benoit Chabot. (2000) Control of hnRNP A1 Alternative Splicing: an Intron Element Represses Use of the Common 3′ Splice Site. Molecular and Cellular Biology 20:19, pages 7353-7362.
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William G. Fairbrother & Lawrence A. Chasin. (2000) Human Genomic Sequences That Inhibit Splicing. Molecular and Cellular Biology 20:18, pages 6816-6825.
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Hanzhen Sun & Lawrence A. Chasin. (2000) Multiple Splicing Defects in an Intronic False Exon. Molecular and Cellular Biology 20:17, pages 6414-6425.
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Michael Belshan, Gregory S. Park, Patricia Bilodeau, C. Martin Stoltzfus & Susan Carpenter. (2000) Binding of Equine Infectious Anemia Virus Rev to an Exon Splicing Enhancer Mediates Alternative Splicing and Nuclear Export of Viral mRNAs. Molecular and Cellular Biology 20:10, pages 3550-3557.
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Fabienne Del Gatto-Konczak, Michelle Olive, Marie-Claude Gesnel & Richard Breathnach. (1999) hnRNP A1 Recruited to an Exon In Vivo Can Function as an Exon Splicing Silencer. Molecular and Cellular Biology 19:1, pages 251-260.
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Zhi-hai Si, Dan Rauch & C. Martin Stoltzfus. (1998) The Exon Splicing Silencer in Human Immunodeficiency Virus Type 1 Tat Exon 3 Is Bipartite and Acts Early in Spliceosome Assembly. Molecular and Cellular Biology 18:9, pages 5404-5413.
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Fabienne Del Gatto, Ariane Plet, Marie-Claude Gesnel, Cécile Fort & Richard Breathnach. (1997) Multiple Interdependent Sequence Elements Control Splicing of a Fibroblast Growth Factor Receptor 2 Alternative Exon. Molecular and Cellular Biology 17:9, pages 5106-5116.
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Lydia R. Coulter, Mark A. Landree & Thomas A. Cooper. (1997) Identification of a New Class of Exonic Splicing Enhancers by In Vivo Selection. Molecular and Cellular Biology 17:4, pages 2143-2150.
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Richard R. Gontarek & David Derse. (1996) Interactions among SR Proteins, an Exonic Splicing Enhancer, and a Lentivirus Rev Protein Regulate Alternative Splicing. Molecular and Cellular Biology 16:5, pages 2325-2331.
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Huicheng Tian & Ryszard Kole. (1995) Selection of Novel Exon Recognition Elements from a Pool of Random Sequences. Molecular and Cellular Biology 15:11, pages 6291-6298.
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Fabienne Del Gatto & Richard Breathnach. (1995) Exon and Intron Sequences, Respectively, Repress and Activate Splicing of a Fibroblast Growth Factor Receptor 2 Alternative Exon. Molecular and Cellular Biology 15:9, pages 4825-4834.
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Mary Beth Humphrey, Joseph Bryan, Thomas A. Cooper & Susan M. Berget. (1995) A 32-Nucleotide Exon-Splicing Enhancer Regulates Usage of Competing 5′ Splice Sites in a Differential Internal Exon. Molecular and Cellular Biology 15:8, pages 3979-3988.
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Articles from other publishers (22)

Jeffrey Kuniholm, Carolyn Coote & Andrew J. Henderson. (2022) Defective HIV-1 genomes and their potential impact on HIV pathogenesis. Retrovirology 19:1.
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Raabya Rossenkhan, Iain J. MacLeod, Theresa K. Sebunya, Eduardo Castro-Nallar, Mary Fran McLane, Rosemary Musonda, Berhanu A. Gashe, Vlad Novitsky & M. Essex. (2013) tat Exon 1 Exhibits Functional Diversity during HIV-1 Subtype C Primary Infection . Journal of Virology 87:10, pages 5732-5745.
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Steffen Erkelenz, Gereon Poschmann, Stephan Theiss, Anja Stefanski, Frank Hillebrand, Marianne Otte, Kai Stühler & Heiner Schaal. (2013) Tra2-Mediated Recognition of HIV-1 5′ Splice Site D3 as a Key Factor in the Processing of vpr mRNA . Journal of Virology 87:5, pages 2721-2734.
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Atze T. Das, Alex Harwig & Ben Berkhout. (2011) The HIV-1 Tat Protein Has a Versatile Role in Activating Viral Transcription. Journal of Virology 85:18, pages 9506-9516.
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Dibyakanti Mandal, Zehua Feng & C. Martin Stoltzfus. (2010) Excessive RNA Splicing and Inhibition of HIV-1 Replication Induced by Modified U1 Small Nuclear RNAs. Journal of Virology 84:24, pages 12790-12800.
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C. M. Exline, Z. Feng & C. M. Stoltzfus. (2008) Negative and Positive mRNA Splicing Elements Act Competitively To Regulate Human Immunodeficiency Virus Type 1 Vif Gene Expression. Journal of Virology 82:8, pages 3921-3931.
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Jenny L. Anderson, Adam T. Johnson, Jane L. Howard & Damian F. J. Purcell. (2007) Both Linear and Discontinuous Ribosome Scanning Are Used for Translation Initiation from Bicistronic Human Immunodeficiency Virus Type 1 env mRNAs . Journal of Virology 81:9, pages 4664-4676.
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Tsuyoshi Kashima, Nishta Rao & James L. Manley. (2007) An intronic element contributes to splicing repression in spinal muscular atrophy. Proceedings of the National Academy of Sciences 104:9, pages 3426-3431.
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Takeshi FukuharaTakamitsu HosoyaSaki Shimizu, Kengo SumiTakako OshiroYoshiyuki YoshinakaMasaaki SuzukiNaoki Yamamoto, Leonore A. Herzenberg, Leonard A. Herzenberg & Masatoshi Hagiwara. (2006) Utilization of host SR protein kinases and RNA-splicing machinery during viral replication. Proceedings of the National Academy of Sciences 103:30, pages 11329-11333.
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Joshua M. Madsen & C. Martin Stoltzfus. (2005) An Exonic Splicing Silencer Downstream of the 3′ Splice Site A2 Is Required for Efficient Human Immunodeficiency Virus Type 1 Replication. Journal of Virology 79:16, pages 10478-10486.
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Massimo Caputi, Marcel Freund, Susanne Kammler, Corinna Asang & Heiner Schaal. (2004) A Bidirectional SF2/ASF- and SRp40-Dependent Splicing Enhancer Regulates Human Immunodeficiency Virus Type 1 rev , env , vpu , and nef Gene Expression . Journal of Virology 78:12, pages 6517-6526.
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Secondo Sonza, Helen P. Mutimer, Kate O'Brien, Philip Ellery, Jane L. Howard, Jonathan H. Axelrod, Nicholas J. Deacon, Suzanne M. Crowe & Damian F. J. Purcell. (2002) Selectively Reduced tat mRNA Heralds the Decline in Productive Human Immunodeficiency Virus Type 1 Infection in Monocyte-Derived Macrophages . Journal of Virology 76:24, pages 12611-12621.
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Jodi Pongoski, Kengo Asai & Alan Cochrane. (2002) Positive and Negative Modulation of Human Immunodeficiency Virus Type 1 Rev Function by cis and trans Regulators of Viral RNA Splicing . Journal of Virology 76:10, pages 5108-5120.
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Patricia S. Bilodeau, Jeffrey K. DomsicAkila Mayeda, Adrian R. Krainer & C. Martin Stoltzfus. (2001) RNA Splicing at Human Immunodeficiency Virus Type 1 3′ Splice Site A2 Is Regulated by Binding of hnRNP A/B Proteins to an Exonic Splicing Silencer Element. Journal of Virology 75:18, pages 8487-8497.
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Andreas Bültmann, Walter Muranyi, Brian Seed & Jürgen Haas. (2001) Identification of Two Sequences in the Cytoplasmic Tail of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein That Inhibit Cell Surface Expression. Journal of Virology 75:11, pages 5263-5276.
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Koen VerhoefPatricia S. Bilodeau, Jeroen L. B. van WamelJørgen Kjems, C. Martin Stoltzfus & Ben Berkhout. (2001) Repair of a Rev-Minus Human Immunodeficiency Virus Type 1 Mutant by Activation of a Cryptic Splice Site. Journal of Virology 75:7, pages 3495-3500.
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Zhi-Ming Zheng, Eric S. Reid & Carl C. Baker. (2000) Utilization of the Bovine Papillomavirus Type 1 Late-Stage-Specific Nucleotide 3605 3′ Splice Site Is Modulated by a Novel Exonic Bipartite Regulator but Not by an Intronic Purine-Rich Element. Journal of Virology 74:22, pages 10612-10622.
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Patricia S. Bilodeau, Jeffrey K. Domsic & C. Martin Stoltzfus. (1999) Splicing Regulatory Elements within tat Exon 2 of Human Immunodeficiency Virus Type 1 (HIV-1) Are Characteristic of Group M but Not Group O HIV-1 Strains . Journal of Virology 73:12, pages 9764-9772.
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Lisa M. McNally & Mark T. McNally. (1999) U1 Small Nuclear Ribonucleoprotein and Splicing Inhibition by the Rous Sarcoma Virus Negative Regulator of Splicing Element. Journal of Virology 73:3, pages 2385-2393.
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Zhi Ming Zheng, Pei-jun He & Carl C. Baker. (1999) Function of a Bovine Papillomavirus Type 1 Exonic Splicing Suppressor Requires a Suboptimal Upstream 3′ Splice Site. Journal of Virology 73:1, pages 29-36.
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Zhi Ming Zheng, Martijn Huynen & Carl C. Baker. (1998) A pyrimidine-rich exonic splicing suppressor binds multiple RNA splicing factors and inhibits spliceosome assembly. Proceedings of the National Academy of Sciences 95:24, pages 14088-14093.
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Sharon D. Chandler, Akila Mayeda, Joanne M. Yeakley, Adrian R. Krainer & Xiang-Dong Fu. (1997) RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins. Proceedings of the National Academy of Sciences 94:8, pages 3596-3601.
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