Citations (29)
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Read on this site (10)
Bradley W. Christensen, Vlad G Zaha & Farrukh T. Awan. (2022) Cardiotoxicity of BTK inhibitors: ibrutinib and beyond. Expert Review of Hematology 15:4, pages 321-331.
Read now
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Leslie J. Crofford, Lindsay E. Nyhoff, Jonathan H. Sheehan & Peggy L. Kendall. (2016) The role of Bruton’s tyrosine kinase in autoimmunity and implications for therapy. Expert Review of Clinical Immunology 12:7, pages 763-773.
Read now
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Helena Block & Alexander Zarbock. (2012) The Role of the Tec Kinase Bruton's Tyrosine Kinase (Btk) in Leukocyte Recruitment. International Reviews of Immunology 31:2, pages 104-118.
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Joseph J. Buggy & Laurence Elias. (2012) Bruton Tyrosine Kinase (BTK) and Its Role in B-cell Malignancy. International Reviews of Immunology 31:2, pages 119-132.
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Rudi W Hendriks, Robbert GM Bredius, Karin Pike-Overzet & Frank JT Staal. (2011) Biology and novel treatment options for XLA, the most common monogenetic immunodeficiency in man. Expert Opinion on Therapeutic Targets 15:8, pages 1003-1021.
Read now
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Xiaochuan Shan, Michael J. Czar, Stephen C. Bunnell, Pinghu Liu, Yusen Liu, Pamela L. Schwartzberg & Ronald L. Wange. (2000) Deficiency of PTEN in Jurkat T Cells Causes Constitutive Localization of Itk to the Plasma Membrane and Hyperresponsiveness to CD3 Stimulation. Molecular and Cellular Biology 20:18, pages 6945-6957.
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Carl D. Novina, Sanjay Kumar, Urmila Bajpai, Venugopalan Cheriyath, Keming Zhang, Shiv Pillai, Henry H. Wortis & Ananda L. Roy. (1999) Regulation of Nuclear Localization and Transcriptional Activity of TFII-I by Bruton’s Tyrosine Kinase. Molecular and Cellular Biology 19:7, pages 5014-5024.
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Jayantha Debnath, Mario Chamorro, Michael J. Czar, Edward M. Schaeffer, Michael J. Lenardo, Harold E. Varmus & Pamela L. Schwartzberg. (1999) rlk/TXK Encodes Two Forms of a Novel Cysteine String Tyrosine Kinase Activated by Src Family Kinases. Molecular and Cellular Biology 19:2, pages 1498-1507.
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Daniel E. H. Afar, Hyunsun Park, Brian W. Howell, David J. Rawlings, Jonathan Cooper & Owen N. Witte. (1996) Regulation of Btk by Src Family Tyrosine Kinases. Molecular and Cellular Biology 16:7, pages 3465-3471.
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Jennifer A. Taylor, Jennifer L. Karas, Mary K. Ram, O. M. Green & Cynthia Seidel-Dugan. (1995) Activation of the High-Affinity Immunoglobulin E Receptor FcεRI in RBL-2H3 Cells Is Inhibited by Syk SH2 Domains. Molecular and Cellular Biology 15:8, pages 4149-4157.
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Articles from other publishers (19)
Mark Sabat, Douglas R Dougan, Beverly Knight, J. David Lawson, Nicholas Scorah, Christopher R Smith, Ewan R Taylor, Phong Vu, Corey Wyrick, Haixia Wang, Deepika Balakrishna, Mark Hixon, Loui Madakamutil & Donavon McConn. (2021)
Discovery of the Bruton’s Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (
S
)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3
H
-1,2,4-triazol-3-one, by Fragment-Based Drug Design
. Journal of Medicinal Chemistry 64:17, pages 12893-12902.
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Xianhui Wang, Leila Kokabee, Mostafa Kokabee & Douglas S. Conklin. (2021) Bruton’s Tyrosine Kinase and Its Isoforms in Cancer. Frontiers in Cell and Developmental Biology 9.
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Qi WangYakov PecherskyShiori SagawaAlbert C. PanDavid E. Shaw. (2019) Structural mechanism for Bruton’s tyrosine kinase activation at the cell membrane. Proceedings of the National Academy of Sciences 116:19, pages 9390-9399.
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Archana S. Iyer & Avery August. (2008) The Tec Family Kinase, IL-2-Inducible T Cell Kinase, Differentially Controls Mast Cell Responses. The Journal of Immunology 180:12, pages 7869-7877.
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Renaud Lesourne, Wolf H. Fridman & Marc Daëron. (2005) Dynamic Interactions of Fcγ Receptor IIB with Filamin-Bound SHIP1 Amplify Filamentous Actin-Dependent Negative Regulation of Fcε Receptor I Signaling. The Journal of Immunology 174:3, pages 1365-1373.
Crossref
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Mari Maeda-Yamamoto, Naoki Inagaki, Jiro Kitaura, Takao Chikumoto, Hiroharu Kawahara, Yuko Kawakami, Mitsuaki Sano, Toshio Miyase, Hirofumi Tachibana, Hiroichi Nagai & Toshiaki Kawakami. (2004)
O
-Methylated Catechins from Tea Leaves Inhibit Multiple Protein Kinases in Mast Cells
. The Journal of Immunology 172:7, pages 4486-4492.
Crossref
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Yuko Kawakami, Jiro Kitaura, Libo Yao, Robert W. McHenry, Yu Kawakami, Alexandra C. Newton, Shin Kang, Roberta M. Kato, Michael Leitges, David J. Rawlings & Toshiaki Kawakami. (2003) A Ras activation pathway dependent on Syk phosphorylation of protein kinase C. Proceedings of the National Academy of Sciences 100:16, pages 9470-9475.
Crossref
Crossref
Yun Qiu & Hsing-Jien Kung. (2000) Signaling network of the Btk family kinases. Oncogene 19:49, pages 5651-5661.
Crossref
Crossref
Niklas Ekman, Elena Arighi, Iiro Rajantie, Pipsa Saharinen, Ari Ristimäki, Olli Silvennoinen & Kari Alitalo. (2000) The Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent manner. Oncogene 19:36, pages 4151-4158.
Crossref
Crossref
Yuko Kawakami, Jiro Kitaura, Stephen E. Hartman, Clifford A. Lowell, Reuben P. Siraganian & Toshiaki Kawakami. (2000) Regulation of protein kinase CβI by two protein-tyrosine kinases, Btk and Syk. Proceedings of the National Academy of Sciences 97:13, pages 7423-7428.
Crossref
Crossref
Yuko Kawakami, Stephen E. Hartman, Eiji Kinoshita, Hidefumi Suzuki, Jiro Kitaura, Libo Yao, Naoki Inagaki, Alessandra Franco, Daisuke Hata, Mari Maeda-Yamamoto, Hiromi Fukamachi, Hiroichi Nagai & Toshiaki Kawakami. (1999) Terreic acid, a quinone epoxide inhibitor of Bruton’s tyrosine kinase. Proceedings of the National Academy of Sciences 96:5, pages 2227-2232.
Crossref
Crossref
Tamotsu Ishizuka, Kosuke Chayama, Katsuyuki Takeda, Eckard Hamelmann, Naohiro Terada, Gordon M. Keller, Gary L. Johnson & Erwin W. Gelfand. (1999) Mitogen-Activated Protein Kinase Activation Through Fcε Receptor I and Stem Cell Factor Receptor Is Differentially Regulated by Phosphatidylinositol 3-Kinase and Calcineurin in Mouse Bone Marrow-Derived Mast Cells. The Journal of Immunology 162:4, pages 2087-2094.
Crossref
Crossref
Michael Huber, Cheryl D. Helgason, Jacqueline E. Damen, Ling Liu, R. Keith Humphries & Gerald Krystal. (1998) The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation. Proceedings of the National Academy of Sciences 95:19, pages 11330-11335.
Crossref
Crossref
R. Csonga, E. E. Prieschl, D. Jaksche, V. Novotny & T. Baumruker. (1998) Common and Distinct Signaling Pathways Mediate the Induction of TNF-α and IL-5 in IgE Plus Antigen-Stimulated Mast Cells. The Journal of Immunology 160:1, pages 273-283.
Crossref
Crossref
Anne B. Satterthwaite, Hilde Cheroutre, Wasif N. Khan, Pascalis Sideras & Owen N. Witte. (1997) Btk dosage determines sensitivity to B cell antigen receptor cross-linking. Proceedings of the National Academy of Sciences 94:24, pages 13152-13157.
Crossref
Crossref
Matthew I. Wahl, Anne-Catherine Fluckiger, Roberta M. Kato, Hyunsun Park, Owen N. Witte & David J. Rawlings. (1997) Phosphorylation of two regulatory tyrosine residues in the activation of Bruton’s tyrosine kinase via alternative receptors. Proceedings of the National Academy of Sciences 94:21, pages 11526-11533.
Crossref
Crossref
Avery August, Ali Sadra, Bo Dupont & Hidesaburo Hanafusa. (1997) Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase. Proceedings of the National Academy of Sciences 94:21, pages 11227-11232.
Crossref
Crossref
Tamotsu Ishizuka, Naohiro Terada, Pär Gerwins, Eckard Hamelmann, Akihiro Oshiba, Gary R. Fanger, Gary L. Johnson & Erwin W. Gelfand. (1997) Mast cell tumor necrosis factor α production is regulated by MEK kinases. Proceedings of the National Academy of Sciences 94:12, pages 6358-6363.
Crossref
Crossref
Yuko Kawakami, Toru Miura, Reid Bissonnette, Daisuke Hata, Wasif N. Khan, Toshio Kitamura, Mari Maeda-Yamamoto, Stephen E. Hartman, Libo Yao, Frederick W. Alt & Toshiaki Kawakami. (1997) Bruton’s tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity. Proceedings of the National Academy of Sciences 94:8, pages 3938-3942.
Crossref
Crossref