Advanced search
Publication Cover
Molecular and Cellular Biology Volume 7, 1987 - Issue 9
Submit an article Journal homepage
3
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Structural Significance of the GTP-Binding Domain Of ras p21 Studied by Site-Directed Mutagenesis

David J. ClantonLaboratory of Molecular Oncology, National Cancer Institute, National Institutes of Health, Frederick, Maryland21701
,
You Yong LuLaboratory of Molecular Oncology, National Cancer Institute, National Institutes of Health, Frederick, Maryland21701
,
Donald G. BlairLaboratory of Molecular Oncology, National Cancer Institute, National Institutes of Health, Frederick, Maryland21701
&
Thomas Y. ShihLaboratory of Molecular Oncology, National Cancer Institute, National Institutes of Health, Frederick, Maryland21701
Pages 3092-3097 | Received 23 Mar 1987, Accepted 11 Jun 1987, Published online: 31 Mar 2023

Citations (6)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (6)

Matthew R. Pincus, Paul W. Brandt-Rauf, Joseph Michl, Robert P. Carty & Fred K. Friedman. (2000) ras-p21-Induced Cell Transformation: Unique Signal Transduction Pathways and Implications for the Design of New Chemotherapeutic Agents. Cancer Investigation 18:1, pages 39-50.
Read now
Harald Mischak, Thomas Seitz, Petra Janosch, Manfred Eulitz, Helge Steen, Miriam Schellerer, Alex Philipp & Walter Kolch. (1996) Negative Regulation of Raf-1 by Phosphorylation of Serine 621. Molecular and Cellular Biology 16:10, pages 5409-5418.
Read now
DaryllC. Dykes, Paul Brandt-Rauf, SharonM. Luster, Denise Chung, FredK. Friedman & MatthewR. Pincus. (1992) Activated Conformations of the ras-gene-Encoded p21 Protein. 1. An Energy-Refined Structure for the Normal p21 Protein Complexed with GDP. Journal of Biomolecular Structure and Dynamics 9:6, pages 1025-1044.
Read now
JamesM. Chen, Grace Lee, RandallB. Murphy, RobertP. Carty, PaulW. Brandt-Rauf, Edward Friedman & MatthewR. Pincus. (1989) Comparison of the Computed Structures for the Phosphate-Binding Loop of the p21 Protein Containing the Oncogenic Site Gly 12 with the X-ray Crystallographic Structures for this Region in the p21 Protein and EFtu. A Model for the Structure of the p21 Protein in its Oncogenic Form. Journal of Biomolecular Structure and Dynamics 6:5, pages 859-875.
Read now
Larry A. Feig & Geoffrey M. Cooper. (1988) Inhibition of NIH 3T3 Cell Proliferation by a Mutant ras Protein with Preferential Affinity for GDP. Molecular and Cellular Biology 8:8, pages 3235-3243.
Read now
Larry A. Feig & Geoffrey M. Cooper. (1988) Relationship Among Guanine Nucleotide Exchange, GTP Hydrolysis, and Transforming Potential of Mutated ras Proteins. Molecular and Cellular Biology 8:6, pages 2472-2478.
Read now

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.