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Research Article

The Muscle Creatine Kinase Gene Is Regulated by Multiple Upstream Elements, Including a Muscle-Specific Enhancer

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Pages 62-70 | Received 12 Jun 1987, Accepted 24 Sep 1987, Published online: 31 Mar 2023

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Charis L. Himeda, Jeffrey A. Ranish, Richard C. M. Pearson, Merlin Crossley & Stephen D. Hauschka. (2010) KLF3 Regulates Muscle-Specific Gene Expression and Synergizes with Serum Response Factor on KLF Binding Sites. Molecular and Cellular Biology 30:14, pages 3430-3443.
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Charis L. Himeda, Jeffrey A. Ranish & Stephen D. Hauschka. (2008) Quantitative Proteomic Identification of MAZ as a Transcriptional Regulator of Muscle-Specific Genes in Skeletal and Cardiac Myocytes . Molecular and Cellular Biology 28:20, pages 6521-6535.
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S. Molinari, F. Relaix, M. Lemonnier, B. Kirschbaum, B. Schäfer & M. Buckingham. (2004) A Novel Complex Regulates cardiac actin Gene Expression through Interaction of Emb, a Class VI POU Domain Protein, MEF2D, and the Histone Transacetylase p300. Molecular and Cellular Biology 24:7, pages 2944-2957.
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Charis L. Himeda, Jeffrey A. Ranish, John C. Angello, Pascal Maire, Ruedi Aebersold & Stephen D. Hauschka. (2004) Quantitative Proteomic Identification of Six4 as the Trex-Binding Factor in the Muscle Creatine Kinase Enhancer. Molecular and Cellular Biology 24:5, pages 2132-2143.
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Saskia T. C. Neuteboom & Cornelis Murre. (1997) Pbx Raises the DNA Binding Specificity but Not the Selectivity of Antennapedia Hox Proteins. Molecular and Cellular Biology 17:8, pages 4696-4706.
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Stephen X. Skapek, James Rhee, Paul S. Kim, Bennett G. Novitch & Andrew B. Lassar. (1996) Cyclin-Mediated Inhibition of Muscle Gene Expression via a Mechanism That Is Independent of pRB Hyperphosphorylation. Molecular and Cellular Biology 16:12, pages 7043-7053.
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Margaret A. Shield, Harald S. Haugen, Christopher H. Clegg & Stephen D. Hauschka. (1996) E-Box Sites and a Proximal Regulatory Region of the Muscle Creatine Kinase Gene Differentially Regulate Expression in Diverse Skeletal Muscles and Cardiac Muscle of Transgenic Mice. Molecular and Cellular Biology 16:9, pages 5058-5068.
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Jing Huang, T. Keith Blackwell, Larry Kedes & Harold Weintraub. (1996) Differences between MyoD DNA Binding and Activation Site Requirements Revealed by Functional Random Sequence Selection. Molecular and Cellular Biology 16:7, pages 3893-3900.
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Dorit B. Donoviel, Margaret A. Shield, Jean N. Buskin, Harald S. Haugen, Christopher H. Clegg & Stephen D. Hauschka. (1996) Analysis of Muscle Creatine Kinase Gene Regulatory Elements in Skeletal and Cardiac Muscles of Transgenic Mice. Molecular and Cellular Biology 16:4, pages 1649-1658.
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F. Catala, R. Wanner, P. Barton, A. Cohen, W. Wright & M. Buckingham. (1995) A Skeletal Muscle-Specific Enhancer Regulated by Factors Binding to E and CArG Boxes Is Present in the Promoter of the Mouse Myosin Light-Chain 1A Gene. Molecular and Cellular Biology 15:8, pages 4585-4596.
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Hon S. Ip, David B. Wilson, Markku Heikinheimo, Zhihua Tang, Chao-Nan Ting, M. Celeste Simon, Jeffrey M. Leiden & Michael S. Parmacek. (1994) The GATA-4 Transcription Factor Transactivates the Cardiac Muscle-Specific Troponin C Promoter-Enhancer in Nonmuscle Cells. Molecular and Cellular Biology 14:11, pages 7517-7526.
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Sutip Navankasattusas, Michele Sawadogo, Marc Van Bilsen, Chi V. Dang & Kenneth R. Chien. (1994) The Basic Helix-Loop-Helix Protein Upstream Stimulating Factor Regulates the Cardiac Ventricular Myosin Light-Chain 2 Gene via Independent cis Regulatory Elements. Molecular and Cellular Biology 14:11, pages 7331-7339.
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Sunkara S. Rao, Caryn Chu & D. Stave Kohtz. (1994) Ectopic Expression of Cyclin D1 Prevents Activation of Gene Transcription by Myogenic Basic Helix-Loop-Helix Regulators. Molecular and Cellular Biology 14:8, pages 5259-5267.
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Michael S. Parmacek, Hon S. Ip, Frank Jung, Tingliang Shen, James F. Martin, Anuradha J. Vora, Eric N. Olson & Jeffrey M. Leiden. (1994) A Novel Myogenic Regulatory Circuit Controls Slow/Cardiac Troponin C Gene Transcription in Skeletal Muscle. Molecular and Cellular Biology 14:3, pages 1870-1885.
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Atsushi Asakura, Atsuko Fujisawa-Sehara, Tohru Komiya, Yoko Nabeshima & Yo-Ichi Nabeshima. (1993) MyoD and Myogenin Act on the Chicken Myosin Light-Chain 1 Gene as Distinct Transcriptional Factors. Molecular and Cellular Biology 13:11, pages 7153-7162.
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Thorkil H. Christensen, Howard Prentice, Reinhold Gahlmann & Larry Kedes. (1993) Regulation of the Human Cardiac/Slow-Twitch Troponin C Gene by Multiple, Cooperative, Cell-Type-Specific, and MyoD-Responsive Elements. Molecular and Cellular Biology 13:11, pages 6752-6765.
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Doris A. Taylor, Virginia B. Kraus, John J. Schwarz, Eric N. Olson & William E. Kraus. (1993) E1A-Mediated Inhibition of Myogenesis Correlates with a Direct Physical Interaction of E1A12S and Basic Helix-Loop-Helix Proteins. Molecular and Cellular Biology 13:8, pages 4714-4727.
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Gretchen Bain, Stefan Gruenwald & Cornelis Murre. (1993) E2A and E2-2 are Subunits of B-Cell-Specific E2-Box DNA-Binding Proteins. Molecular and Cellular Biology 13:6, pages 3522-3529.
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Sharon L. Amacher, Jean N. Buskin & Stephen D. Hauschka. (1993) Multiple Regulatory Elements Contribute Differentially to Muscle Creatine Kinase Enhancer Activity in Skeletal and Cardiac Muscle. Molecular and Cellular Biology 13:5, pages 2753-2764.
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Christopher K. Vincent, Antonio Gualberto, Chandrashekhar V. Patel & Kenneth Walsh. (1993) Different Regulatory Sequences Control Creatine Kinase-M Gene Expression in Directly Injected Skeletal and Cardiac Muscle. Molecular and Cellular Biology 13:2, pages 1264-1272.
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Jing-Shan Hu, Eric N. Olson & Robert E. Kingston. (1992) HEB, a Helix-Loop-Helix Protein Related to E2A and ITF2 That Can Modulate the DNA-Binding Ability of Myogenic Regulatory Factors. Molecular and Cellular Biology 12:3, pages 1031-1042.
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John J. Schwarz, Tushar Chakraborty, James Martin, Jumin Zhou & Eric N. Olson. (1992) The Basic Region of Myogenin Cooperates with Two Transcription Activation Domains To Induce Muscle-Specific Transcription. Molecular and Cellular Biology 12:1, pages 266-275.
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Tushar Chakraborty & Eric N. Olson. (1991) Domains Outside of the DNA-Binding Domain Impart Target Gene Specificity to Myogenin and MRF4. Molecular and Cellular Biology 11:12, pages 6103-6108.
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Tushar Chakraborty, Thomas J. Brennan, Li Li, Diane Edmondson & Eric N. Olson. (1991) Inefficient Homooligomerization Contributes to the Dependence of Myogenin on E2A Products for Efficient DNA Binding. Molecular and Cellular Biology 11:7, pages 3633-3641.
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Irma M. Santoro, Tau-Mu Yi & Kenneth Walsh. (1991) Identification of Single-Stranded-DNA-Binding Proteins That Interact with Muscle Gene Elements. Molecular and Cellular Biology 11:4, pages 1944-1953.
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Joshua R. Schultz, Terese Tansey, Linda Gremke & Robert V. Storti. (1991) A Muscle-Specific Intron Enhancer Required for Rescue of Indirect Flight Muscle and Jump Muscle Function Regulates Drosophila Tropomyosin I Gene Expression. Molecular and Cellular Biology 11:4, pages 1901-1911.
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  Ruoqian-Shen, Shyamal K. Goswami, Eduardo Mascareno, Ashok Kumar & M. A. Q. Siddiqui. (1991) Tissue-Specific Transcription of the Cardiac Myosin Light-Chain 2 Gene Is Regulated by an Upstream Repressor Element. Molecular and Cellular Biology 11:3, pages 1676-1685.
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Robert A. Horlick, Grace M. Hobson, James H. Patterson, Mark T. Mitchell & Pamela A. Benfield. (1990) Brain and Muscle Creatine Kinase Genes Contain Common TA-Rich Recognition Protein-Binding Regulatory Elements. Molecular and Cellular Biology 10:9, pages 4826-4836.
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Janet H. Mar & Charles P. Ordahl. (1990) M-CAT Binding Factor, a Novel trans-Acting Factor Governing Muscle-Specific Transcription. Molecular and Cellular Biology 10:8, pages 4271-4283.
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Katherine E. Yutzey, Simon J. Rhodes & Stephen F. Konieczny. (1990) Differential trans Activation Associated with the Muscle Regulatory Factors MyoD1, Myogenin, and MRF4. Molecular and Cellular Biology 10:8, pages 3934-3944.
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Zhanjiang Liu, Boaz Moav, Anthony J. Faras, Kevin S. Guise, Anne R. Kapuscinski & Perry B. Hackett. (1990) Functional Analysis of Elements Affecting Expression of the β-Actin Gene of Carpt. Molecular and Cellular Biology 10:7, pages 3432-3440.
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Lani A. Gossett, David J. Kelvin, Edward A. Sternberg & Eric N. Olson. (1989) A New Myocyte-Specific Enhancer-Binding Factor That Recognizes a Conserved Element Associated with Multiple Muscle-Specific Genes. Molecular and Cellular Biology 9:11, pages 5022-5033.
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Jane E. Johnson, Barbara J. Wold & Stephen D. Hauschka. (1989) Muscle Creatine Kinase Sequence Elements Regulating Skeletal and Cardiac Muscle Expression in Transgenic Mice. Molecular and Cellular Biology 9:8, pages 3393-3399.
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Wolfgang W. Quitschke, Liliana Deponti-Zilli, Ze-Yu Lin & Bruce M. Paterson. (1989) Identification of Two Nuclear Factor-Binding Domains on the Chicken Cardiac Actin Promoter: Implications for Regulation of the Gene. Molecular and Cellular Biology 9:8, pages 3218-3230.
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Jean N. Buskin & Stephen D. Hauschka. (1989) Identification of a Myocyte Nuclear Factor That Binds to the Muscle-Specific Enhancer of the Mouse Muscle Creatine Kinase Gene. Molecular and Cellular Biology 9:6, pages 2627-2640.
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Robert A. Horlick & Pamela A. Benfield. (1989) The Upstream Muscle-Specific Enhancer of the Rat Muscle Creatine Kinase Gene Is Composed of Multiple Elements. Molecular and Cellular Biology 9:6, pages 2396-2413.
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Kenneth Walsh. (1989) Cross-Binding of Factors to Functionally Different Promoter Elements in c-fos and Skeletal Actin Genes. Molecular and Cellular Biology 9:5, pages 2191-2201.
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Paul Bornstein, John McKay, Deann J. Liska, Stephen Apone & Sreelekha Devarayalu. (1988) Interactions between the Promoter and First Intron Are Involved in Transcriptional Control of α1(I) Collagen Gene Expression. Molecular and Cellular Biology 8:11, pages 4851-4857.
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Heeja Yoo-Warren, Vassilis Pachnis, Robert S. Ingram & Shirley M. Tilghman. (1988) Two Regulatory Domains Flank the Mouse H19 Gene. Molecular and Cellular Biology 8:11, pages 4707-4715.
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Elizabeth A. Bucher, Peter C. Maisonpierre, Stephen F. Konieczny & Charles P. Emerson$suffix/text()$suffix/text(). (1988) Expression of the Troponin Complex Genes: Transcriptional Coactivation during Myoblast Differentiation and Independent Control in Heart and Skeletal Muscles. Molecular and Cellular Biology 8:10, pages 4134-4142.
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