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Molecular and Cellular Biology Volume 8, 1988 - Issue 2
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Research Article

A Fetal Globin Gene Mutation in Aϒ Nondeletion Hereditary Persistence of Fetal Hemoglobin Increases Promoter Strength in a Nonerythroid Cell

Mark W. Rixon1 Department of Molecular Medicine, Fred Hutchinson Cancer Research Center, Seattle, Washington98104
&
Richard E. Gelinas1 Department of Molecular Medicine, Fred Hutchinson Cancer Research Center, Seattle, Washington98104
Pages 713-721 | Received 31 Aug 1987, Accepted 04 Nov 1987, Published online: 31 Mar 2023

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Susanna Harju-Baker, Flávia C. Costa, Halyna Fedosyuk, Renee Neades & Kenneth R. Peterson. (2008) Silencing of Aγ-Globin Gene Expression during Adult Definitive Erythropoiesis Mediated by GATA-1-FOG-1-Mi2 Complex Binding at the −566 GATA Site. Molecular and Cellular Biology 28:10, pages 3101-3113.
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Susanna Harju, Patrick A. Navas, George Stamatoyannopoulos & Kenneth R. Peterson. (2005) Genome Architecture of the Human β-Globin Locus Affects Developmental Regulation of Gene Expression. Molecular and Cellular Biology 25:20, pages 8765-8778.
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Kenneth R. Peterson & George Stamatoyannopoulos. (1993) Role of Gene Order in Developmental Control of Human γ- and β-Globin Gene Expression. Molecular and Cellular Biology 13:8, pages 4836-4843.
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David N. Cooper. (1992) Regulatory Mutations and Human Genetic Disease. Annals of Medicine 24:6, pages 427-437.
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Nadya L. Lumelsky & Bernard G. Forget. (1991) Negative Regulation of Globin Gene Expression during Megakaryocytic Differentiation of a Human Erythroleukemic Cell Line. Molecular and Cellular Biology 11:7, pages 3528-3536.
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Kathryn Sykes & Russel Kaufman. (1990) A Naturally Occurring Gamma Globin Gene Mutation Enhances SP1 Binding Activity. Molecular and Cellular Biology 10:1, pages 95-102.
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S. Ottolenghi, R. Mantovani, S. Nicolis, A. Ronchi & B. Giglioni. (1989) DNA Sequences Regulating Human Globin Gene Transcription in Nondeletional Hereditary Persistence of Fetal Hemoglobin. Hemoglobin 13:6, pages 523-541.
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Deborah L. Gumucio, Kirsten L. Rood, Todd A. Gray, Maureen F. Riordan, Carolyn I. Sartor & Francis S. Collins. (1988) Nuclear Proteins That Bind the Human ϒ-Globin Gene Promoter: Alterations in Binding Produced by Point Mutations Associated with Hereditary Persistence of Fetal Hemoglobin. Molecular and Cellular Biology 8:12, pages 5310-5322.
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