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Molecular and Cellular Biology Volume 8, 1988 - Issue 7
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Research Article

Expression of Recombinant Platelet-Derived Growth Factor A-and B-Chain Homodimers in Rat-1 Cells and Human Fibroblasts Reveals Differences in Protein Processing and Autocrine Effects

Margaret Bywater1 Department of Pathology, University Hospital, National Canocer Institute, Uppsala, Sweden
,
Fredrik Rorsman1 Department of Pathology, University Hospital, National Canocer Institute, Uppsala, Sweden
,
Erik Bongcam-Rudloff1 Department of Pathology, University Hospital, National Canocer Institute, Uppsala, Sweden
,
George Mark2 Laboratory of Humnan Carcinogenesis, National Canocer Institute, Bethesda, Maryland
,
Annet Hammacher3 Ludwvig Institute for Cancer Research, Uppsala Brancsh, National Canocer Institute, Uppsala, Sweden
,
Carl-Henrik Heldin3 Ludwvig Institute for Cancer Research, Uppsala Brancsh, National Canocer Institute, Uppsala, Sweden
,
Bengt Westermark1 Department of Pathology, University Hospital, National Canocer Institute, Uppsala, Sweden
&
Christer Betsholtz1 Department of Pathology, University Hospital, National Canocer Institute, Uppsala, Sweden
 show all
Pages 2753-2762 | Received 22 Dec 1987, Accepted 08 Apr 1988, Published online: 31 Mar 2023

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Levon M. Khachigian & Colin N. Chesterman. (1992) Platelet-Derived Growth Factor and Alternative Splicing: A Review. Pathology 24:4, pages 280-290.
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Brona Matoskova, Fredrik Rorsman, Viveka Svensson & Christer Betsholtz. (1989) Alternative Splicing of the Platelet-Derived Growth Factor A-Chain Transcript Occurs in Normal as Well as Tumor Cells and Is Conserved among Mammalian Species. Molecular and Cellular Biology 9:7, pages 3148-3150.
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Arne Östman, Gudrun Bäckström, Noel Fong, Christer Betsholtz, Christer Wernstedt, Ulf Hellman, Bengt Westermark, Pablo Valenzuela & Carl-Henrik Heldin. (1989) Expression of Three Recombinant Homodimeric Isoforms of PDGF in Saccharomyces cerevisiae: Evidence for Difference in Receptor Binding and Functional Activities. Growth Factors 1:3, pages 271-281.
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