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Gene Expression

Mutagenesis of the Rat Insulin II 5′-Flanking Region Defines Sequences Important for Expression in HIT Cells

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Pages 1784-1789 | Received 01 Aug 1988, Accepted 03 Jan 1989, Published online: 31 Mar 2023

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Yi Qiu, Min Guo, Suming Huang & Roland Stein. (2002) Insulin Gene Transcription Is Mediated by Interactions between the p300 Coactivator and PDX-1, BETA2, and E47. Molecular and Cellular Biology 22:2, pages 412-420.
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Arun Sharma, Melissa Moore, Edoardo Marcora, Jacqueline E. Lee, Yi Qiu, Susan Samaras & Roland Stein. (1999) The NeuroD1/BETA2 Sequences Essential for Insulin Gene Transcription Colocalize with Those Necessary for Neurogenesis and p300/CREB Binding Protein Binding. Molecular and Cellular Biology 19:1, pages 704-713.
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Yi Qiu, Arun Sharma & Roland Stein. (1998) p300 Mediates Transcriptional Stimulation by the Basic Helix-Loop-Helix Activators of the Insulin Gene. Molecular and Cellular Biology 18:5, pages 2957-2964.
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Mina Peshavaria, Eva Henderson, Arun Sharma, Christopher V. E. Wright & Roland Stein. (1997) Functional Characterization of the Transactivation Properties of the PDX-1 Homeodomain Protein. Molecular and Cellular Biology 17:7, pages 3987-3996.
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Michael Peyton, Christine M. M. Stellrecht, Francisco J. Naya, Hsiang-Po Huang, Patrick J. Samora & Ming-Jer Tsai. (1996) BETA3, a Novel Helix-Loop-Helix Protein, Can Act as a Negative Regulator of BETA2 and MyoD-Responsive Genes. Molecular and Cellular Biology 16:2, pages 626-633.
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Gary L. W. G. Robinson, Eva Henderson, Mark E. Massari, Cornelis Murre & Roland Stein. (1995) c-jun inhibits insulin control element-mediated transcription by affecting the transactivation potential of the E2A gene products. Molecular and Cellular Biology 15:3, pages 1398-1404.
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Gary L. W. G. Robinson, Susan R. Cordle, Eva Henderson, P. Anthony Weil, Gladys Teitelman & Roland Stein. (1994) Isolation and Characterization of a Novel Transcription Factor That Binds to and Activates Insulin Control Element-Mediated Expression. Molecular and Cellular Biology 14:10, pages 6704-6714.
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Michael S. German & Juehu Wang. (1994) The Insulin Gene Contains Multiple Transcriptional Elements That Respond to Glucose. Molecular and Cellular Biology 14:6, pages 4067-4075.
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Arun Sharma & Roland Stein. (1994) Glucose-Induced Transcription of the Insulin Gene Is Mediated by Factors Required for β-Cell-Type-Specific Expression. Molecular and Cellular Biology 14:2, pages 871-879.
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Eva Henderson & Roland Stein. (1994) c-jun inhibits transcriptional activation by the insulin enhancer, and the insulin control element is the target of control. Molecular and Cellular Biology 14:1, pages 655-662.
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Doris A. Taylor, Virginia B. Kraus, John J. Schwarz, Eric N. Olson & William E. Kraus. (1993) E1A-Mediated Inhibition of Myogenesis Correlates with a Direct Physical Interaction of E1A12S and Basic Helix-Loop-Helix Proteins. Molecular and Cellular Biology 13:8, pages 4714-4727.
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Marc Therrien & Jacques Drouin. (1993) Cell-Specific Helix-Loop-Helix Factor Required for Pituitary Expression of the Pro-Opiomelanocortin Gene. Molecular and Cellular Biology 13:4, pages 2342-2353.
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Kathy D. Shelton, Alan J. Franklin, Andras Khoor, Joseph Beechem & Mark A. Magnuson. (1992) Multiple Elements in the Upstream Glucokinase Promoter Contribute to Transcription in Insulinoma Cells. Molecular and Cellular Biology 12:10, pages 4578-4589.
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Michael S. German, Larry Gene Moss, Juehu Wang & William J. Rutter. (1992) The Insulin and Islet Amyloid Polypeptide Genes Contain Similar Cell-Specific Promoter Elements That Bind Identical β-Cell Nuclear Complexes. Molecular and Cellular Biology 12:4, pages 1777-1788.
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Susan R. Cordle, James Whelan, Eva Henderson, Howard Masuoka, P. Anthony Weil & Roland Stein. (1991) NOTES/Insulin Gene Expression in Nonexpressing Cells Appears To Be Regulated by Multiple Distinct Negative-Acting Control Elements. Molecular and Cellular Biology 11:5, pages 2881-2886.
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Susan R. Cordle, Eva Henderson, Howard Masuoka, P. Anthony Weil & Roland Stein. (1991) Pancreatic β-Cell-Type-Specific Transcription of the Insulin Gene Is Mediated by Basic Helix-Loop-Helix DNA-Binding Proteins. Molecular and Cellular Biology 11:3, pages 1734-1738.
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Young-Ping Hwung, Yi-Zhong Gu & Ming-Jer Tsai. (1990) Cooperativity of Sequence Elements Mediates Tissue Specificity of the Rat Insulin II Gene. Molecular and Cellular Biology 10:4, pages 1784-1788.
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Roland W. Stein & James Whelan. (1989) Notes: Insulin Gene Enhancer Activity Is Inhibited by Adenovirus 5 E1a Gene Products. Molecular and Cellular Biology 9:10, pages 4531-4534.
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James Whelan, David Poon, P. Anthony Weil & Roland Stein. (1989) Pancreatic β-Cell-Type-Specific Expression of the Rat Insulin II Gene Is Controlled by Positive and Negative Cellular Transcriptional Elements. Molecular and Cellular Biology 9:8, pages 3253-3259.
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Articles from other publishers (1)

Maike Sander, Steven C. Griffen, Juemin Huang & Michael S. German. (1998) A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets. Proceedings of the National Academy of Sciences 95:20, pages 11572-11577.
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