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Journal of Biomaterials Science, Polymer Edition Volume 20, 2009 - Issue 1
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Review

Molecular Aspects of Mucoadhesive Carrier Development for Drug Delivery and Improved Absorption

Nicholas A. Peppas Departments of Chemical and Biomedical Engineering and Division of Pharmaceutics, The University of Texas at Austin, 1 University Station, C0400, CPE 3.468, Austin, TX 78712, USA
,
J. Brock Thomas Departments of Chemical and Biomedical Engineering and Division of Pharmaceutics, The University of Texas at Austin, 1 University Station, C0400, CPE 3.468, Austin, TX 78712, USA
&
James McGinty Departments of Chemical and Biomedical Engineering and Division of Pharmaceutics, The University of Texas at Austin, 1 University Station, C0400, CPE 3.468, Austin, TX 78712, USA
Pages 1-20 | Published online: 02 Apr 2012

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Radha Kulkarni, Suraj Fanse & Diane J. Burgess. (2023) Mucoadhesive drug delivery systems: a promising non-invasive approach to bioavailability enhancement. Part I: biophysical considerations. Expert Opinion on Drug Delivery 20:3, pages 395-412.
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Amresh Kumar, Pradeep Kumar Naik, Deepak Pradhan, Goutam Ghosh & Goutam Rath. (2020) Mucoadhesive formulations: innovations, merits, drawbacks, and future outlook. Pharmaceutical Development and Technology 25:7, pages 797-814.
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Abdelbasset Atia, Ahmed I. Gomma, Ismail Fliss, Eric Beyssac, Ghislain Garrait & Muriel Subirade. (2017) Molecular and biopharmaceutical investigation of alginate–inulin synbiotic coencapsulation of probiotic to target the colon. Journal of Microencapsulation 34:2, pages 171-184.
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Flavia Laffleur. (2016) Mucoadhesive therapeutic compositions: a patent review (2011-2014). Expert Opinion on Therapeutic Patents 26:3, pages 377-388.
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Flavia Laffleur. (2014) Mucoadhesive polymers for buccal drug delivery. Drug Development and Industrial Pharmacy 40:5, pages 591-598.
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James C. DiNunzio, Justin R. Hughey, Chris Brough, Dave A. Miller, Robert O. Williams III & James W. McGinity. (2010) Production of advanced solid dispersions for enhanced bioavailability of itraconazole using KinetiSol® Dispersing. Drug Development and Industrial Pharmacy 36:9, pages 1064-1078.
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Melissa Kanzelberger Coolich, Olivia L. Lanier, Ethan Cisneros & Nicholas A. Peppas. (2023) PEGylated insulin loaded complexation hydrogels for protected oral delivery. Journal of Controlled Release 364, pages 216-226.
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Hideyuki Sato, Kohei Yamada, Masateru Miyake & Satomi Onoue. (2023) Recent Advancements in the Development of Nanocarriers for Mucosal Drug Delivery Systems to Control Oral Absorption. Pharmaceutics 15:12, pages 2708.
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Fabiola A. Chapa-Villarreal, Matthew Miller, J Jesus Rodriguez-Cruz, Diego Pérez-Carlos & Nicholas A. Peppas. (2023) Self-assembled block copolymer biomaterials for oral delivery of protein therapeutics. Biomaterials 300, pages 122191.
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Laura Müller, Christoph Rosenbaum, Adrian Rump, Michael Grimm, Friederike Klammt, Annabel Kleinwort, Alexandra Busemann & Werner Weitschies. (2023) Determination of Mucoadhesion of Polyvinyl Alcohol Films to Human Intestinal Tissue. Pharmaceutics 15:6, pages 1740.
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Heidi F Oldenkamp, Julia E Vela Ramirez & Nicholas A Peppas. (2019) Re-evaluating the importance of carbohydrates as regenerative biomaterials. Regenerative Biomaterials 6:1, pages 1-12.
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Bao‑Zhong Jin, Xiao‑Qi Dong, Xin Xu & Feng‑He Zhang. (2017) Development and in�vitro evaluation of mucoadhesive patches of methotrexate for targeted delivery in oral cancer. Oncology Letters.
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