Publication Cover
Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 28, 2006 - Issue 5
143
Views
60
CrossRef citations to date
0
Altmetric
Articles

Human neural stem cell differentiation following transplantation into spinal cord injured mice: association with recovery of locomotor function

, , &
Pages 474-481 | Published online: 19 Jul 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Aminul I. Ahmed, Malik Zaben & William P. Gray. (2011) Stem cells in the adult human brain. British Journal of Neurosurgery 25:1, pages 28-37.
Read now
J. Louro & D. D. Pearse. (2008) Stem and progenitor cell therapies: recent progress for spinal cord injury repair. Neurological Research 30:1, pages 5-16.
Read now
Dimitrios Karussis & Ibrahim Kassis. (2007) Use of stem cells for the treatment of multiple sclerosis. Expert Review of Neurotherapeutics 7:9, pages 1189-1201.
Read now

Articles from other publishers (57)

Miriam Aceves, Ashley Tucker, Joseph Chen, Katie Vo, Joshua Moses, Prakruthi Amar Kumar, Hannah Thomas, Diego Miranda, Gabrielle Dampf, Valerie Dietz, Matthew Chang, Aleena Lukose, Julius Jang, Sneha Nadella, Tucker Gillespie, Christian Trevino, Andrew Buxton, Anna L. Pritchard, Peyton Green, Dylan A. McCreedy & Jennifer N. Dulin. (2023) Developmental stage of transplanted neural progenitor cells influences anatomical and functional outcomes after spinal cord injury in mice. Communications Biology 6:1.
Crossref
Ashley Tucker, Miriam Aceves, Jessica C. Butts & Jennifer N. Dulin. 2023. Spinal Interneurons. Spinal Interneurons 381 422 .
Sungjoon Lee, Hyun Nam, Kyeung-Min Joo & Sun-Ho Lee. (2022) Advances in Neural Stem Cell Therapy for Spinal Cord Injury: Safety, Efficacy, and Future Perspectives. Neurospine 19:4, pages 946-960.
Crossref
Madeleine J. Smith, Madison Claire Badawy Paton, Michael C. Fahey, Graham Jenkin, Suzanne L. Miller, Megan Finch-Edmondson & Courtney A. McDonald. (2021) Neural Stem Cell Treatment for Perinatal Brain Injury: A Systematic Review and Meta-Analysis of Preclinical Studies. Stem Cells Translational Medicine 10:12, pages 1621-1636.
Crossref
Francisca Benavente, Katja M Piltti, Mitra J Hooshmand, Aileen A Nava, Anita Lakatos, Brianna G Feld, Dana Creasman, Paul D Gershon & Aileen Anderson. (2020) Novel C1q receptor-mediated signaling controls neural stem cell behavior and neurorepair. eLife 9.
Crossref
Juan C Biancotti, Kendal A Walker, Guihua Jiang, Julie Di Bernardo, Lonnie D Shea & Shaun M Kunisaki. (2020) Hydrogel and neural progenitor cell delivery supports organotypic fetal spinal cord development in an ex vivo model of prenatal spina bifida repair . Journal of Tissue Engineering 11, pages 204173142094383.
Crossref
V. A. Smirnov & A. A. Grin. (2019) Regenerative treatment of spinal cord injury. Literature review. Part 3. Russian journal of neurosurgery 21:4, pages 97-103.
Crossref
Lin Xia, Wenjuan Zhu, Yunfeng Wang, Shuangba He & Renjie Chai. (2019) Regulation of Neural Stem Cell Proliferation and Differentiation by Graphene-Based Biomaterials. Neural Plasticity 2019, pages 1-11.
Crossref
Artem B Kutikov, Simon W Moore, Richard T Layer, Pamela E Podell, Nithya Sridhar, Andrea J Santamaria, Alex A Aimetti, Christoph P Hofstetter, Thomas R Ulich & James D Guest. (2019) Method and Apparatus for the Automated Delivery of Continuous Neural Stem Cell Trails Into the Spinal Cord of Small and Large Animals. Neurosurgery 85:4, pages 560-573.
Crossref
Xiao-Ming Zhao, Xiu-Ying HeJia Liu, Yang Xu, Fei-Fei Xu, Ya-Xin Tan, Zi-Bin Zhang & Ting-Hua Wang. (2019) Neural Stem Cell Transplantation Improves Locomotor Function in Spinal Cord Transection Rats Associated with Nerve Regeneration and IGF-1 R Expression. Cell Transplantation 28:9-10, pages 1197-1211.
Crossref
Sreenivasa Raghavan Sankavaram, Ramil Hakim, Ruxandra Covacu, Arvid Frostell, Susanne Neumann, Mikael Svensson & Lou Brundin. (2019) Adult Neural Progenitor Cells Transplanted into Spinal Cord Injury Differentiate into Oligodendrocytes, Enhance Myelination, and Contribute to Recovery. Stem Cell Reports 12:5, pages 950-966.
Crossref
Lyandysha V. Zholudeva & Michael A. Lane. (2019) Transplanting Cells for Spinal Cord Repair: Who, What, When, Where and Why?. Cell Transplantation 28:4, pages 388-399.
Crossref
Allan D. LeviKim D. AndersonDavid O. OkonkwoPaul ParkThomas N. BryceShekar N. KurpadBizhan AarabiJane HsiehKatie Gant. (2019) Clinical Outcomes from a Multi-Center Study of Human Neural Stem Cell Transplantation in Chronic Cervical Spinal Cord Injury. Journal of Neurotrauma 36:6, pages 891-902.
Crossref
Jiayi WangWei ZouJingyun MaJing Liu. (2019) Biomaterials and Gene Manipulation in Stem Cell-Based Therapies for Spinal Cord Injury. Stem Cells and Development 28:4, pages 239-257.
Crossref
Allan D Levi, David O Okonkwo, Paul Park, Arthur L Jenkins, Shekar N Kurpad, Ann M Parr, Aruna Ganju, Bizhan Aarabi, Dong Kim, Steven Casha, Michael G Fehlings, James S Harrop, Kim D Anderson, Allyson Gage, Jane Hsieh, Stephen Huhn, Armin Curt & Raphael Guzman. (2018) Emerging Safety of Intramedullary Transplantation of Human Neural Stem Cells in Chronic Cervical and Thoracic Spinal Cord Injury. Neurosurgery 82:4, pages 562-575.
Crossref
George M. Ghobrial, Kim D. Anderson, Marine Dididze, Jasmine Martinez-Barrizonte, Gabriel H. Sunn, Katie L. Gant & Allan D. Levi. (2017) Human Neural Stem Cell Transplantation in Chronic Cervical Spinal Cord Injury. Neurosurgery 64:CN_suppl_1, pages 87-91.
Crossref
Arash Sarveazad, Asrin Babahajian, Mehrdad Bakhtiari, Mansoureh Soleimani, Babak Behnam, Abazar Yari, Abolfazl Akbari, Mahmoud Yousefifard, Atousa Janzadeh, Naser Amini, Shahram Agah, Ali Fallah & Mohammad Taghi Joghataei. (2017) The combined application of human adipose derived stem cells and Chondroitinase ABC in treatment of a spinal cord injury model. Neuropeptides 61, pages 39-47.
Crossref
E. Sundström. 2017. Bioresorbable Polymers for Biomedical Applications. Bioresorbable Polymers for Biomedical Applications 525 542 .
Ina K. Simeonova & Armin Blesch. 2017. Neurological Aspects of Spinal Cord Injury. Neurological Aspects of Spinal Cord Injury 585 619 .
Klaus Zweckberger, Christopher S. Ahuja, Yang Liu, Jian Wang & Michael G. Fehlings. (2016) Self-assembling peptides optimize the post-traumatic milieu and synergistically enhance the effects of neural stem cell therapy after cervical spinal cord injury. Acta Biomaterialia 42, pages 77-89.
Crossref
Ivan Cheng, Michael Githens, Robert L. Smith, Tyler R. Johnston, Don Y. Park, Michael P. Stauff, Nima Salari, Kali R. Tileston & Alexander I. Kharazi. (2016) Local versus distal transplantation of human neural stem cells following chronic spinal cord injury. The Spine Journal 16:6, pages 764-769.
Crossref
Aileen J. Anderson & Brian J. Cummings. (2021) Achieving Informed Consent for Cellular Therapies: A Preclinical Translational Research Perspective on Regulations versus a Dose of Reality. Journal of Law, Medicine & Ethics 44:3, pages 394-401.
Crossref
Paul Lu, Ruhel Ahmad & Mark H. Tuszynski. 2016. Translational Neuroscience. Translational Neuroscience 297 315 .
Janessa Chang, Michael Phelan & Brian J. Cummings. (2015) A meta-analysis of efficacy in pre-clinical human stem cell therapies for traumatic brain injury. Experimental Neurology 273, pages 225-233.
Crossref
Dasa Cizkova, Lucia Slovinska, Ivana Grulova, Michel Salzet, Stefan Cikos, Olga Kryukov & Smadar Cohen. (2015) The influence of sustained dual-factor presentation on the expansion and differentiation of neural progenitors in affinity-binding alginate scaffolds. Journal of Tissue Engineering and Regenerative Medicine 9:8, pages 918-929.
Crossref
Beatrice Sandner, Peter Prang, Armin Blesch & Norbert Weidner. 2015. Neural Stem Cells in Development, Adulthood and Disease. Neural Stem Cells in Development, Adulthood and Disease 155 174 .
Christopher J. Sontag, Nobuko Uchida, Brian J. Cummings & Aileen J. Anderson. (2014) Injury to the Spinal Cord Niche Alters the Engraftment Dynamics of Human Neural Stem Cells. Stem Cell Reports 2:5, pages 620-632.
Crossref
Motoyuki Iwasaki, Jared T. Wilcox, Yusuke Nishimura, Klaus Zweckberger, Hidenori Suzuki, Jian Wang, Yang Liu, Spyridon K. Karadimas & Michael G. Fehlings. (2014) Synergistic effects of self-assembling peptide and neural stem/progenitor cells to promote tissue repair and forelimb functional recovery in cervical spinal cord injury. Biomaterials 35:9, pages 2617-2629.
Crossref
R. Vawda, M. Soubeyrand, J.A. Zuccato & M.G. Fehlings. 2014. Pathobiology of Human Disease. Pathobiology of Human Disease 593 638 .
Stephanie Merchant, Sarah Stegeman & Kiminobu Sugaya. 2014. Handbook of Neurotoxicity. Handbook of Neurotoxicity 2299 2314 .
Ann Tsukamoto, Nobuko Uchida, Alexandra Capela, Thorsten Gorba & Stephen Huhn. (2013) Clinical translation of human neural stem cells. Stem Cell Research & Therapy 4:4.
Crossref
Andrea J. Mothe & Charles H. Tator. (2013) Review of transplantation of neural stem/progenitor cells for spinal cord injury. International Journal of Developmental Neuroscience 31:7, pages 701-713.
Crossref
Sebastiaan van Gorp, Marjolein Leerink, Osamu Kakinohana, Oleksandr Platoshyn, Camila Santucci, Jan Galik, Elbert A Joosten, Marian Hruska-Plochan, Danielle Goldberg, Silvia Marsala, Karl Johe, Joseph D Ciacci & Martin Marsala. (2013) Amelioration of motor/sensory dysfunction and spasticity in a rat model of acute lumbar spinal cord injury by human neural stem cell transplantation. Stem Cell Research & Therapy 4:3.
Crossref
Alexa L. Reeves & Hans Keirstead. 2006. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Encyclopedia of Molecular Cell Biology and Molecular Medicine.
John Fisher, Antonios Mikos, Joseph Bronzino & Donald PetersonYen-Chih Lin & Kacey Marra. 2012. Tissue Engineering. Tissue Engineering 1 22 .
Beatrice Sandner, Peter Prang, Francisco J. Rivera, Ludwig Aigner, Armin Blesch & Norbert Weidner. (2012) Neural stem cells for spinal cord repair. Cell and Tissue Research 349:1, pages 349-362.
Crossref
R. Vawda, J. Wilcox & Michael G. Fehlings. (2012) Current stem cell treatments for spinal cord injury. Indian Journal of Orthopaedics 46:1, pages 10-18.
Crossref
Jun-Feng Feng, Jing Liu, Xiu-Zhen Zhang, Lei Zhang, Ji-Yao Jiang, Jan Nolta & Min Zhao. (2012) Guided Migration of Neural Stem Cells Derived from Human Embryonic Stem Cells by an Electric Field. Stem Cells 30:2, pages 349-355.
Crossref
Daniel Becker & John W. McdonaldIIIIII. 2012. Spinal Cord Injury. Spinal Cord Injury 445 461 .
Michael G. Fehlings & Reaz Vawda. (2011) Cellular Treatments for Spinal Cord Injury: The Time is Right for Clinical Trials. Neurotherapeutics 8:4, pages 704-720.
Crossref
Jiachuan Wang, Mei Tian & Hong Zhang. (2011) PET molecular imaging in stem cell therapy for neurological diseases. European Journal of Nuclear Medicine and Molecular Imaging 38:10, pages 1926-1938.
Crossref
K. E. Thomas & L. D. F. Moon. (2011) Will stem cell therapies be safe and effective for treating spinal cord injuries?. British Medical Bulletin 98:1, pages 127-142.
Crossref
Martin M. Mortazavi, Ketan Verma, R. Shane Tubbs & Nicholas Theodore. (2010) Cellular and paracellular transplants for spinal cord injury: a review of the literature. Child's Nervous System 27:2, pages 237-243.
Crossref
A. Sannino, M. Madaghiele, M. Carrozzo, L. Salvatore & L. Ambrosio. 2011. Comprehensive Biomaterials. Comprehensive Biomaterials 435 453 .
Mihir S. Shanbhag, Justin D. Lathia, Mohamed R. Mughal, Nicola L. Francis, Nicholas Pashos, Mark P. Mattson & Margaret A. Wheatley. (2010) Neural Progenitor Cells Grown on Hydrogel Surfaces Respond to the Product of the Transgene of Encapsulated Genetically Engineered Fibroblasts. Biomacromolecules 11:11, pages 2936-2943.
Crossref
Li Cao, Lifang Mu, Yang Qiu, Zhida Su, Yanling Zhu, Liang Gao, Yimin Yuan, Dazhi Guo & Cheng He. (2010) Diffusible, membrane-bound, and extracellular matrix factors from olfactory ensheathing cells have different effects on the self-renewing and differentiating properties of neural stem cells. Brain Research 1359, pages 56-66.
Crossref
Gizelda T.B. Casella, Vania W. Almeida, Robert M. Grumbles, Yang Liu & Christine K. Thomas. (2010) Neurotrophic factors improve muscle reinnervation from embryonic neurons. Muscle & Nerve 42:5, pages 788-797.
Crossref
Desir?e L. Salazar, Nobuko Uchida, Frank P. T. Hamers, Brian J. Cummings & Aileen J. Anderson. (2010) Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal coRd Injury NOD-scid Mouse Model. PLoS ONE 5:8, pages e12272.
Crossref
GE Rooney, GI Nistor, FB Barry & HS Keirstead. (2010) In vitro  differentiation potential of human embryonic versus adult stem cells . Regenerative Medicine 5:3, pages 365-379.
Crossref
Azadeh Farin, Charles Y. Liu, Iver A. Langmoen & Michael L.J. Apuzzo. (2009) BIOLOGICAL RESTORATION OF CENTRAL NERVOUS SYSTEM ARCHITECTURE AND FUNCTION. Neurosurgery 65:5, pages 831-859.
Crossref
Sharyn L Rossi & Hans S Keirstead. (2009) Stem cells and spinal cord regeneration. Current Opinion in Biotechnology 20:5, pages 552-562.
Crossref
Christopher Thomas Scott. (2008) Stem cells: new frontiers of ethics, law, and policy. Neurosurgical Focus 24:3-4, pages E24.
Crossref
Margaret Coutts & Hans S. Keirstead. (2008) Stem cells for the treatment of spinal cord injury. Experimental Neurology 209:2, pages 368-377.
Crossref
F. Wang & Y. Zhu. (2008) The interaction of Nogo-66 receptor with Nogo-p4 inhibits the neuronal differentiation of neural stem cells. Neuroscience 151:1, pages 74-81.
Crossref
Stephanie M. Willerth & Shelly E. Sakiyama-Elbert. (2008) Cell therapy for spinal cord regeneration. Advanced Drug Delivery Reviews 60:2, pages 263-276.
Crossref
Brett T. Lund & Eve E. Kelland. 2008. Neural Stem Cells. Neural Stem Cells 227 241 .
Tingting Lin, Omedul Islam & Klaus Heese. (2006) ABC transporters, neural stem cells and neurogenesis – a different perspective. Cell Research 16:11, pages 857-871.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.