1,079
Views
30
CrossRef citations to date
0
Altmetric
Original Article

Imatinib induces autophagy through BECLIN‐1 and ATG5 genes in chronic myeloid leukemia cells

, &
Pages 95-99 | Received 01 Jun 2010, Accepted 19 Jul 2010, Published online: 12 Nov 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Subhadip Mukhopadhyay, Niharika Sinha, Durgesh Nandini Das, Prashanta Kumar Panda, Prajna Paramita Naik & Sujit Kumar Bhutia. (2016) Clinical relevance of autophagic therapy in cancer: Investigating the current trends, challenges, and future prospects. Critical Reviews in Clinical Laboratory Sciences 53:4, pages 228-252.
Read now
Tao Wu, Min-Cong Wang, Li Jing, Zhi-Yan Liu, Hui Guo, Ying Liu, Yi-Yang Bai, Yang-Zi Cheng, Ke-Jun Nan & Xuan Liang. (2015) Autophagy facilitates lung adenocarcinoma resistance to cisplatin treatment by activation of AMPK/mTOR signaling pathway. Drug Design, Development and Therapy 9, pages 6421-6431.
Read now
Xielan Zhao, Juan Liu, Minyuan Peng, Jing Liu & Fangping Chen. (2013) BMP4 is Involved in the Chemoresistance of Myeloid Leukemia Cells Through Regulating Autophagy–Apoptosis Balance. Cancer Investigation 31:8, pages 555-562.
Read now

Articles from other publishers (27)

Yan Chen, Xiaozhen Zhang, Hanshen Yang, Tingbo Liang & Xueli Bai. (2023) The “Self-eating” of cancer-associated fibroblast: A potential target for cancer. Biomedicine & Pharmacotherapy 163, pages 114762.
Crossref
Tamara Marín, Andrés E. Dulcey, Fabián Campos, Catalina de la Fuente, Mariana Acuña, Juan Castro, Claudio Pinto, María José Yañez, Cristian Cortez, David W. McGrath, Pablo J. Sáez, Kirill Gorshkov, Wei Zheng, Noel Southall, Maria Carmo-Fonseca, Juan Marugán, Alejandra R. Alvarez & Silvana Zanlungo. (2022) c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease. Frontiers in Cell and Developmental Biology 10.
Crossref
Kihyoun Park & Myung-Shik Lee. (2022) Current Status of Autophagy Enhancers in Metabolic Disorders and Other Diseases. Frontiers in Cell and Developmental Biology 10.
Crossref
Oana Herlea-Pana, Venkateswararao Eeda, Ram Babu Undi, Hui-Ying Lim & Weidong Wang. (2021) Pharmacological Inhibition of Inositol-Requiring Enzyme 1α RNase Activity Protects Pancreatic Beta Cell and Improves Diabetic Condition in Insulin Mutation-Induced Diabetes. Frontiers in Endocrinology 12.
Crossref
Surbhi Verma, Raman Deep Sharma & Dhiraj Kumar. 2021. Advances in Host-Directed Therapies Against Tuberculosis. Advances in Host-Directed Therapies Against Tuberculosis 71 95 .
Pablo S. Contreras, Pablo J. Tapia, Lila González-Hódar, Ivana Peluso, Chiara Soldati, Gennaro Napolitano, Maria Matarese, Macarena Las Heras, Cristian Valls, Alexis Martinez, Elisa Balboa, Juan Castro, Nancy Leal, Frances M. Platt, Andrzej Sobota, Dominic Winter, Andrés D. Klein, Diego L. Medina, Andrea Ballabio, Alejandra R. Alvarez & Silvana Zanlungo. (2020) c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder. iScience 23:11, pages 101691.
Crossref
João Agostinho Machado-Neto, Juan Luiz Coelho-Silva, Fábio Pires de Souza Santos, Priscila Santos Scheucher, Paulo Vidal Campregher, Nelson Hamerschlak, Eduardo Magalhães Rego & Fabiola Traina. (2019) Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2V617F cells. Investigational New Drugs 38:3, pages 733-745.
Crossref
Matthias Höllerhage, Natascha Fussi, Thomas W. Rösler, Wolfgang Wurst, Christian Behrends & Günter U. Höglinger. (2019) Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons. Neuropharmacology 149, pages 13-26.
Crossref
Peng-Hsu Chen, Ann-Jeng Liu, Kuo-Hao Ho, Ya-Ting Chiu, Zhe-Harn Anne Lin, Yi-Ting Lee, Chwen-Ming Shih & Ku-Chung Chen. (2018) microRNA-199a/b-5p enhance imatinib efficacy via repressing WNT2 signaling-mediated protective autophagy in imatinib-resistant chronic myeloid leukemia cells. Chemico-Biological Interactions 291, pages 144-151.
Crossref
X Liu, K Rothe, R Yen, C Fruhstorfer, T Maetzig, M Chen, D L Forrest, R K Humphries & X Jiang. (2017) A novel AHI-1–BCR-ABL–DNM2 complex regulates leukemic properties of primitive CML cells through enhanced cellular endocytosis and ROS-mediated autophagy. Leukemia 31:11, pages 2376-2387.
Crossref
Yong-Feng Chen, Hao Liu, Xin-Jing Luo, Zhiqiang Zhao, Zhen-You Zou, Jing Li, Xiao-Jing Lin & Yong Liang. (2017) The roles of reactive oxygen species (ROS) and autophagy in the survival and death of leukemia cells. Critical Reviews in Oncology/Hematology 112, pages 21-30.
Crossref
Aysun Adan & Yusuf Baran. (2015) Fisetin and hesperetin induced apoptosis and cell cycle arrest in chronic myeloid leukemia cells accompanied by modulation of cellular signaling. Tumor Biology 37:5, pages 5781-5795.
Crossref
WEI HE, XIUJIN YE, XIANBO HUANG, WEN LEL, LIANGSHUN YOU, LEI WANG, XIAOHUI CHEN & WENBIN QIAN. (2016) Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells. International Journal of Oncology 48:4, pages 1710-1720.
Crossref
He Liu, Zhaoyue He & Hans-Uwe Simon. 2016. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging 253 265 .
Stephanie M. TortorellaAndrew HungTom C. Karagiannis. (2015) The Implication of Cancer Progenitor Cells and the Role of Epigenetics in the Development of Novel Therapeutic Strategies for Chronic Myeloid Leukemia. Antioxidants & Redox Signaling 22:16, pages 1425-1462.
Crossref
Yi-ming Ma, Wei Han, Jia Li, Li-hong Hu & Yu-bo Zhou. (2015) Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro. Acta Pharmacologica Sinica 36:4, pages 517-527.
Crossref
Özlem Tüfekçi, Melis Kartal Yandım, Hale Ören, Gülersu İrken & Yusuf Baran. (2015) Targeting FoxM1 transcription factor in T-cell acute lymphoblastic leukemia cell line. Leukemia Research 39:3, pages 342-347.
Crossref
Katharina Rothe, Hanyang LinKevin B. L. LinAmy Leung, Hui Mi WangMehrnoush MalekesmaeiliRyan R. BrinkmanDonna L. Forrest, Sharon M. Gorski & Xiaoyan Jiang. (2014) The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells. Blood 123:23, pages 3622-3634.
Crossref
Isabel Nascimento-Ferreira, Clévio Nóbrega, Ana Vasconcelos-Ferreira, Isabel Onofre, David Albuquerque, Célia Aveleira, Hirokazu Hirai, Nicole Déglon & Luís Pereira de Almeida. (2013) Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado–Joseph disease. Brain 136:7, pages 2173-2188.
Crossref
Fuquan Zhang & Jit Kong Cheong. (2013) Targeting Oncogene-Induced Autophagy: A New Approach in Cancer Therapy?. Journal of Cancer Research 2013, pages 1-10.
Crossref
Xin Li, Huai-long Xu, Yong-xi Liu, Na An, Si Zhao & Jin-ku Bao. (2013) Autophagy modulation as a target for anticancer drug discovery. Acta Pharmacologica Sinica 34:5, pages 612-624.
Crossref
Mi Zhou & Renxiao Wang. (2013) Small‐Molecule Regulators of Autophagy and Their Potential Therapeutic Applications. ChemMedChem 8:5, pages 694-707.
Crossref
. 2013. DNA Repair and Cancer. DNA Repair and Cancer 115 118 .
Arpita S. Bharadwaj, Binoy Appukuttan, Phillip A. Wilmarth, Yuzhen Pan, Andrew J. Stempel, Timothy J. Chipps, Eric E. Benedetti, David O. Zamora, Dongseok Choi, Larry L. David & Justine R. Smith. (2013) Role of the retinal vascular endothelial cell in ocular disease. Progress in Retinal and Eye Research 32, pages 102-180.
Crossref
Y Yu, L Yang, M Zhao, S Zhu, R Kang, P Vernon, D Tang & L Cao. (2012) Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells. Leukemia 26:8, pages 1752-1760.
Crossref
Isabel Nascimento-Ferreira & Luís Pereira de Almeida. (2011) Beclin-1 and autophagy: potential for new therapeutics in neurodegeneration. Neurodegenerative Disease Management 1:5, pages 349-351.
Crossref
Akihisa Abe, Hiroyuki Yamada, Shota Moriya & Keisuke Miyazawa. (2011) The β-Carboline Alkaloid Harmol Induces Cell Death via Autophagy but Not Apoptosis in Human Non-small Cell Lung Cancer A549 Cells. Biological & Pharmaceutical Bulletin 34:8, pages 1264-1272.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.