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Original Article

Inhibition of Stat3 expression induces apoptosis and suppresses proliferation in human leukemia HL-60 cells

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Pages 232-235 | Published online: 12 Nov 2013

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Mahnaz Mohammadi Kian, Mahdieh Salemi, Mohammad Bahadoran, Atousa Haghi, Nasrin Dashti, Saeed Mohammadi, Shahrbano Rostami, Bahram Chahardouli, Davood Babakhani & Mohsen Nikbakht. (2020) Curcumin Combined with Thalidomide Reduces Expression of STAT3 and Bcl-xL, Leading to Apoptosis in Acute Myeloid Leukemia Cell Lines. Drug Design, Development and Therapy 14, pages 185-194.
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Xiuli Ding, Jiadong Chi, Xue Yang, Jian Hao, Chang Liu, Cuihong Zhu, Xiaodong Wang, Xiaohui Liu, Yangyang Niu, Wei Ji, Dan Chen & Xiongzhi Wu. (2017) Cucurbitacin B synergistically enhances the apoptosis-inducing effect of arsenic trioxide by inhibiting STAT3 phosphorylation in lymphoma Ramos cells. Leukemia & Lymphoma 58:10, pages 2439-2451.
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Articles from other publishers (9)

Yongxiu Huang, Meixi Peng, Huanhuan Qin, Yan Li, Li Pei, Xindong Liu & Xueya Zhao. (2023) LAPTM4B promotes AML progression through regulating RPS9/STAT3 axis. Cellular Signalling 106, pages 110623.
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Mehdi Sajjadi-Dokht, Talar Ahmad Merza Mohamad, Heshu Sulaiman Rahman, Marwah Suliman Maashi, Svetlana Danshina, Navid Shomali, Saeed Solali, Faroogh Marofi, Elham Zeinalzadeh, Morteza Akbari, Ali Adili, Ramin Aslaminabad, Majid Farshdousti Hagh & Mostafa Jarahian. (2022) MicroRNAs and JAK/STAT3 signaling: A new promising therapeutic axis in blood cancers. Genes & Diseases 9:4, pages 849-867.
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Petra AignerTatsuaki MizutaniJaqueline HorvathThomas Eder, Stefan Heber, Karin LindValentin JustHerwig P. Moll, Assa Yeroslaviz, Michael J. M. FischerLukas Kenner, Balázs GyőrffyHeinz SillFlorian Grebien, Richard Moriggl, Emilio Casanova & Dagmar Stoiber. (2019) STAT3β is a tumor suppressor in acute myeloid leukemia. Blood Advances 3:13, pages 1989-2002.
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Lei Wang, Hongyan Zhang & Donghong Lei. (2019) microRNA-146a Promotes Growth of Acute Leukemia Cells by Downregulating Ciliary Neurotrophic Factor Receptor and Activating JAK2/STAT3 Signaling. Yonsei Medical Journal 60:10, pages 924.
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Qiaoyou Weng, Luqing Ren, Lu Guo, Yan Hu, Haixia Zhou, Yuyan Bao, Lingfeng Chen, Guang Liang, Yi Wang & Jichen Ruan. (2016) Curcumin analogue, A13, exhibits anti-leukemia effect via inhibiting STAT3. Tumor Biology 37:7, pages 9959-9966.
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Chunyu Lu, Jufeng Xia, Wang Bin, Yitian Wu, Xiaohui Liu & Yong Zhang. (2015) Advances in diagnosis, treatments, and molecular mechanistic studies of traumatic brain injury. BioScience Trends 9:3, pages 138-148.
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Alexander Rosenberg, Hongtao Fan, Yahui G. Chiu, Rebecca Bolce, Darren Tabechian, Rick Barrett, Sharon Moorehead, Frédéric Baribaud, Hao Liu, Nancy Peffer, David Shealy, Edward M. Schwarz & Christopher T. Ritchlin. (2014) Divergent Gene Activation in Peripheral Blood and Tissues of Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis following Infliximab Therapy. PLoS ONE 9:10, pages e110657.
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Sha Xu, Zhenyu Xu, Baohai Liu, Qing Sun, Ling Yang, Jianmin Wang, Yue Wang & Houqi Liu. (2014) LIFRα-CT3 induces differentiation of a human acute myelogenous leukemia cell line HL-60 by suppressing miR-155 expression through the JAK/STAT Pathway. Leukemia Research 38:10, pages 1237-1244.
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Jing Yang, Wenlin Bai, Piye Niu, Lin Tian & Ai Gao. (2014) Aberrant hypomethylated STAT3 was identified as a biomarker of chronic benzene poisoning through integrating DNA methylation and mRNA expression data. Experimental and Molecular Pathology 96:3, pages 346-353.
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