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Redox Report
Communications in Free Radical Research
Volume 5, 2000 - Issue 4
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The reactivity of myeloperoxidase compound I formed with hypochlorous acid

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Pages 173-178 | Published online: 19 Jul 2013

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Roohi Jeelani, Charalampos Chatzicharalampous, Hamid-Reza Kohan-Ghadr, David Bai, Robert T. Morris, Inga Sliskovic, Awoniyi Awonuga & Husam M. Abu-Soud. (2020) Hypochlorous acid reversibly inhibits caspase-3: a potential regulator of apoptosis. Free Radical Research 54:1, pages 43-56.
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Jürgen Arnhold, Paul G. Furtmüller & Christian Obinger. (2003) Redox properties of myeloperoxidase. Redox Report 8:4, pages 179-186.
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Articles from other publishers (37)

Martina Paumann-Page, Louisa V. Ashby, Irada Khalilova, Nicholas J. Magon, Stefan Hofbauer, Louise N. Paton, Paul G. Furtmüller, Christian Obinger & Anthony J. Kettle. (2023) Hypochlorous acid inactivates myeloperoxidase inside phagocytosing neutrophils. Redox Biochemistry and Chemistry 5-6, pages 100008.
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Gaurav Patil, Hanna Michlits, Paul G. Furtmüller & Stefan Hofbauer. (2023) Reactivity of Coproheme Decarboxylase with Monovinyl, Monopropionate Deuteroheme. Biomolecules 13:6, pages 946.
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Daniel Schmidt, Nikolaus Falb, Ilenia Serra, Marzia Bellei, Vera Pfanzagl, Stefan Hofbauer, Sabine Van Doorslaer, Gianantonio Battistuzzi, Paul G. Furtmüller & Christian Obinger. (2023) Compound I Formation and Reactivity in Dimeric Chlorite Dismutase: Impact of pH and the Dynamics of the Catalytic Arginine. Biochemistry 62:3, pages 835-850.
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Nathália Mariana Pavan, Lucas Michelão Martins, Laís Cristina Augusto, Luiz Carlos da Silva-Filho & Valdecir Farias Ximenes. (2022) Development of fluorescent azapentalenes to study the reactivity of hypochlorous acid and chloramines in micellar systems. Journal of Molecular Liquids 365, pages 120137.
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Jürgen Arnhold & Ernst Malle. (2022) Halogenation Activity of Mammalian Heme Peroxidases. Antioxidants 11:5, pages 890.
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Olivia G. Camp, David Bai, Damla C. Gonullu, Neha Nayak & Husam M. Abu-Soud. (2021) Melatonin interferes with COVID-19 at several distinct ROS-related steps. Journal of Inorganic Biochemistry 223, pages 111546.
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Georg Bauer. (2018) HOCl and the control of oncogenesis. Journal of Inorganic Biochemistry 179, pages 10-23.
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Irene Schaffner, Georg Mlynek, Nicola Flego, Dominic Pühringer, Julian Libiseller-Egger, Leighton Coates, Stefan Hofbauer, Marzia Bellei, Paul G. Furtmüller, Gianantonio Battistuzzi, Giulietta Smulevich, Kristina Djinović-Carugo & Christian Obinger. (2017) Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies. ACS Catalysis 7:11, pages 7962-7976.
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Louisa V. Forbes & Anthony J. Kettle. 2017. Hydrogen Peroxide Metabolism in Health and Disease. Hydrogen Peroxide Metabolism in Health and Disease 281 303 .
Roohi Jeelani, Seyedehameneh Jahanbakhsh, Hamid-Reza Kohan-Ghadr, Mili Thakur, Sana Khan, Sarah R. Aldhaheri, Zhe Yang, Peter Andreana, Robert Morris & Husam M. Abu-Soud. (2017) Mesna (2-mercaptoethane sodium sulfonate) functions as a regulator of myeloperoxidase. Free Radical Biology and Medicine 110, pages 54-62.
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Rajagopal Desikan, Chandrakala Aluganti Narasimhulu, Bobby Khan, Sanjay Rajagopalan & Sampath Parthasarathy. 2017. Mechanisms of Vascular Defects in Diabetes Mellitus. Mechanisms of Vascular Defects in Diabetes Mellitus 535 571 .
Denise Schlorke, Jörg Flemmig, Jana Gau, Paul G. Furtmüller, Christian Obinger & Jürgen Arnhold. (2016) New insights into thiocyanate oxidation by human myeloperoxidase. Journal of Inorganic Biochemistry 162, pages 117-126.
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Fahad A Al-Abbasi. (2015) In vitro activation of dibromoacetonitrile to cyanide by myeloperoxidase . Toxicology and Industrial Health 32:8, pages 1478-1485.
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Abdelrazek B. Abdelrazzak, Stefanie J. Pottgießer, Mark A. Hill, Peter O'Neill & Georg Bauer. (2016) Enhancement of Peroxidase Release from Non-Malignant and Malignant Cells through Low-Dose Irradiation with Different Radiation Quality. Radiation Research 185:2, pages 199.
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Anthony J. Kettle & Christine C. Winterbourn. 2015. Heme Peroxidases. Heme Peroxidases 272 308 .
Faten Shaeib, Sana N. Khan, Iyad Ali, Tohid Najafi, Dhiman Maitra, Ibrahim Abdulhamid, Ghassan M. Saed, Subramaniam Pennathur & Husam M. Abu-Soud. (2015) Melatonin Prevents Myeloperoxidase Heme Destruction and the Generation of Free Iron Mediated by Self-Generated Hypochlorous Acid. PLOS ONE 10:4, pages e0120737.
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Christa Jakopitsch, Katharina F. Pirker, Jörg Flemmig, Stefan Hofbauer, Denise Schlorke, Paul G. Furtmüller, Jürgen Arnhold & Christian Obinger. (2014) Mechanism of reaction of chlorite with mammalian heme peroxidases. Journal of Inorganic Biochemistry 135, pages 10-19.
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Martina Paumann-Page, Paul G. Furtmüller, Stefan Hofbauer, Louise N. Paton, Christian Obinger & Anthony J. Kettle. (2013) Inactivation of human myeloperoxidase by hydrogen peroxide. Archives of Biochemistry and Biophysics 539:1, pages 51-62.
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Dhiman Maitra, Faten Shaeib, Ibrahim Abdulhamid, Rasha M. Abdulridha, Ghassan M. Saed, Michael P. Diamond, Subramaniam Pennathur & Husam M. Abu-Soud. (2013) Myeloperoxidase acts as a source of free iron during steady-state catalysis by a feedback inhibitory pathway. Free Radical Biology and Medicine 63, pages 90-98.
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Jutta Vlasits, Christa Jakopitsch, Margit Bernroitner, Marcel Zamocky, Paul G. Furtmüller & Christian Obinger. (2010) Mechanisms of catalase activity of heme peroxidases. Archives of Biochemistry and Biophysics 500:1, pages 74-81.
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Michael J. DaviesClare L. HawkinsDavid I. PattisonMartin D. Rees. (2008) Mammalian Heme Peroxidases: From Molecular Mechanisms to Health Implications. Antioxidants & Redox Signaling 10:7, pages 1199-1234.
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Daniel R. Ramos, M. Victoria García, Moisés Canle L.J. Arturo Santaballa, Paul G. Furtmüller & Christian Obinger. (2008) Myeloperoxidase-catalyzed chlorination: The quest for the active species. Journal of Inorganic Biochemistry 102:5-6, pages 1300-1311.
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Daniel R. Ramos, M. Victoria García, Moisés Canle L.J. Arturo Santaballa, Paul G. Furtmüller & Christian Obinger. (2007) Myeloperoxidase-catalyzed taurine chlorination: Initial versus equilibrium rate. Archives of Biochemistry and Biophysics 466:2, pages 221-233.
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Jürgen Arnhold, Enrico Monzani, Paul G. Furtmüller, Martina Zederbauer, Luigi Casella & Christian Obinger. (2006) Kinetics and Thermodynamics of Halide and Nitrite Oxidation by Mammalian Heme Peroxidases. European Journal of Inorganic Chemistry 2006:19, pages 3801-3811.
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Paul G. Furtmüller, Martina Zederbauer, Walter Jantschko, Jutta Helm, Martin Bogner, Christa Jakopitsch & Christian Obinger. (2006) Active site structure and catalytic mechanisms of human peroxidases. Archives of Biochemistry and Biophysics 445:2, pages 199-213.
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Holger Spalteholz, Oleg M. Panasenko & Juergen Arnhold. (2006) Formation of reactive halide species by myeloperoxidase and eosinophil peroxidase. Archives of Biochemistry and Biophysics 445:2, pages 225-234.
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Seymour J Klebanoff. (2005) Myeloperoxidase: friend and foe. Journal of Leukocyte Biology 77:5, pages 598-625.
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Holger Spalteholz, Kathrin Wenske & JÜRgen Arnhold. (2005) Interaction of hypohalous acids and heme peroxidases with unsaturated phosphatidylcholines. BioFactors 24:1-4, pages 67-76.
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Yeong-Renn Chen, Chwen-Lih Chen, Xiaoping Liu, Haitao Li, Jay L. Zweier & Ronald P. Mason. (2004) Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c. Free Radical Biology and Medicine 37:10, pages 1591-1603.
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David A King, Diane M Hannum, Jian-Shen Qi & James K Hurst. (2004) HOCl-mediated cell death and metabolic dysfunction in the yeast Saccharomyces cerevisiae. Archives of Biochemistry and Biophysics 423:1, pages 170-181.
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Walter Jantschko, Paul Georg Furtmüller, Martina Zederbauer, Martina Lanz, Christa Jakopitsch & Christian Obinger. (2003) Direct conversion of ferrous myeloperoxidase to compound II by hydrogen peroxide: an anaerobic stopped-flow study. Biochemical and Biophysical Research Communications 312:2, pages 292-298.
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Ana M. Azevedo, Verónica C. Martins, Duarte M.F. Prazeres, Vojislav Vojinović, Joaquim M.S. Cabral & Luís P. Fonseca. 2003. 199 247 .
Walter Jantschko, Paul Georg Furtmüller, Mario Allegra, Maria A. Livrea, Christa Jakopitsch, Günther Regelsberger & Christian Obinger. (2002) Redox Intermediates of Plant and Mammalian Peroxidases: A Comparative Transient-Kinetic Study of Their Reactivity Toward Indole Derivatives. Archives of Biochemistry and Biophysics 398:1, pages 12-22.
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H. Brian Dunford & Leah A. Marquez-Curtis. 2002. Enzyme Kinetics and Mechanism - Part F: Detection and Characterization of Enzyme Reaction Intermediates. Enzyme Kinetics and Mechanism - Part F: Detection and Characterization of Enzyme Reaction Intermediates 338 350 .
Jürgen Arnhold, Paul G. Furtmüller, Günther Regelsberger & Christian Obinger. (2001) Redox properties of the couple compound I/native enzyme of myeloperoxidase and eosinophil peroxidase. European Journal of Biochemistry 268:19, pages 5142-5148.
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Paul Georg Furtmüller, Walter Jantschko, Günther Regelsberger, Christa Jakopitsch, Nicole Moguilevsky & Christian Obinger. (2001) A transient kinetic study on the reactivity of recombinant unprocessed monomeric myeloperoxidase. FEBS Letters 503:2-3, pages 147-150.
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Mario Allegra, Paul Georg Furtmüller, Günther Regelsberger, Maria L. Turco-Liveri, Luisa Tesoriere, Mauro Perretti, Maria A. Livrea & Christian Obinger. (2001) Mechanism of Reaction of Melatonin with Human Myeloperoxidase. Biochemical and Biophysical Research Communications 282:2, pages 380-386.
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