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Redox Report
Communications in Free Radical Research
Volume 8, 2003 - Issue 1
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Oxidative stress in ataxia telangiectasia

Pages 23-29 | Published online: 19 Jul 2013

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Majid Zaki-Dizaji, Seyed Mohammad Akrami, Hassan Abolhassani, Nima Rezaei & Asghar Aghamohammadi. (2017) Ataxia telangiectasia syndrome: moonlighting ATM. Expert Review of Clinical Immunology 13:12, pages 1155-1172.
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Heather L. Armata, Diane Golebiowski, Dae Young Jung, Hwi Jin Ko, Jason K. Kim & Hayla K. Sluss. (2010) Requirement of the ATM/p53 Tumor Suppressor Pathway for Glucose Homeostasis. Molecular and Cellular Biology 30:24, pages 5787-5794.
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Articles from other publishers (64)

Mansi Garg, Lei Li & Roseline Godbout. (2023) Role of DDX1 in the oxidative response of ataxia telangiectasia patient-derived fibroblasts. Redox Biology, pages 102988.
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Jacquelyne Ka‐Li Sun, Genper Chi‐Ngai Wong & Kim Hei‐Man Chow. (2023) Cross‐talk between DNA damage response and the central carbon metabolic network underlies selective vulnerability of Purkinje neurons in ataxia‐telangiectasia . Journal of Neurochemistry.
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Anastasia Ricci, Federica Biancucci, Gianluca Morganti, Mauro Magnani & Michele Menotta. (2022) New human ATM variants are able to regain ATM functions in ataxia telangiectasia disease. Cellular and Molecular Life Sciences 79:12.
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Itana Gomes Alves Andrade, Fabíola Isabel Suano-Souza, Fernando Luiz Affonso Fonseca, Carolina Sanchez Aranda Lago & Roseli Oselka Saccardo Sarni. (2021) Selenium levels and glutathione peroxidase activity in patients with ataxia-telangiectasia: association with oxidative stress and lipid status biomarkers. Orphanet Journal of Rare Diseases 16:1.
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Ji-Hoon Lee & Tanya T. Paull. (2021) Cellular functions of the protein kinase ATM and their relevance to human disease. Nature Reviews Molecular Cell Biology 22:12, pages 796-814.
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Marguerite Blignaut, Sarah Harries, Amanda Lochner & Barbara Huisamen. (2021) Ataxia Telangiectasia Mutated Protein Kinase: A Potential Master Puppeteer of Oxidative Stress-Induced Metabolic Recycling. Oxidative Medicine and Cellular Longevity 2021, pages 1-12.
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Sevgen Tanir Basaranoglu, Sukru Cekic, Emine Kirhan, Melahat Dirican & Sara S. Kilic. (2021) Oxidative stress in common variable immunodeficiency. European Journal of Inflammation 19, pages 205873922110024.
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Yosef Shiloh. (2020) The cerebellar degeneration in ataxia-telangiectasia: A case for genome instability. DNA Repair 95, pages 102950.
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Lara Pizzamiglio, Elisa Focchi & Flavia Antonucci. (2020) ATM Protein Kinase: Old and New Implications in Neuronal Pathways and Brain Circuitry. Cells 9:9, pages 1969.
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Na Li, Xue-Lian Liu, Fa-Li Zhang, Yu Tian, Min Zhu, Ling-Yu Meng, Paul W. Dyce, Wei Shen & Lan Li. (2020) Whole-transcriptome analysis of the toxic effects of zearalenone exposure on ceRNA networks in porcine granulosa cells. Environmental Pollution 261, pages 114007.
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Hei-Man Chow, Aifang Cheng, Xuan Song, Mavis R. Swerdel, Ronald P. Hart & Karl Herrup. (2019) ATM is activated by ATP depletion and modulates mitochondrial function through NRF1. Journal of Cell Biology 218:3, pages 909-928.
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Zheng-Wen Nie, Ying-Jie Niu, Wenjun Zhou, Yong-Han Kim, Kyung-Tae Shin & Xiang-Shun Cui. (2019) Thiamethoxam inhibits blastocyst expansion and hatching via reactive-oxygen species–induced G2 checkpoint activation in pigs. Cellular Signalling 53, pages 294-303.
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Min Jeong Jang, Cha Gon Lee & Hyun Jung Kim. (2018) Novel compound heterozygous mutations of ATM in ataxia-telangiectasia: A case report and calculated prevalence in the Republic of Korea . Journal of Genetic Medicine 15:2, pages 110-114.
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Kok Leong Chong, Benjamin A. Chalmers, Jason K. Cullen, Amandeep Kaur, Jacek L. Kolanowski, Benjamin J. Morrow, Kathryn E. Fairfull-Smith, Martin J. Lavin, Nigel L. Barnett, Elizabeth J. New, Michael P. Murphy & Steven E. Bottle. (2018) Pro-fluorescent mitochondria-targeted real-time responsive redox probes synthesised from carboxy isoindoline nitroxides: Sensitive probes of mitochondrial redox status in cells. Free Radical Biology and Medicine 128, pages 97-110.
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Ji-Hoon Lee, Michael R. Mand, Chung-Hsuan KaoYi ZhouSeung W. Ryu, Alicia L. RichardsJoshua J. CoonTanya T. Paull. (2018) ATM directs DNA damage responses and proteostasis via genetically separable pathways. Science Signaling 11:512.
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Xiang Ding, Yong He, Qiukui Hao, Shanping Chen, Ming Yang, Sean X. Leng, Jirong Yue & Birong Dong. (2018) The association of single nucleotide polymorphism rs189037C>T in ATM gene with coronary artery disease in Chinese Han populations. Medicine 97:4, pages e9747.
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Ali Suliman, Franklin O. Smith & Gary M. Kupfer. 2018. Bone Marrow Failure. Bone Marrow Failure 81 97 .
Catherine D. Kim, Ryan E. Reed, Meredith A. Juncker, Zhide Fang & Shyamal D. Desai. (2017) Evidence for the Deregulation of Protein Turnover Pathways in Atm-Deficient Mouse Cerebellum: An Organotypic Study. Journal of Neuropathology & Experimental Neurology 76:7, pages 578-584.
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Muhammad Torequl Islam, Leticia Streck, Marcus Vinícius Oliveira Barros de Alencar, Samara Wanessa Cardoso Silva, Kátia da Conceição Machado, Keylla da Conceição Machado, Antonio Luiz Gomes Júnior, Márcia Fernanda Correia Jardim Paz, Ana Maria Oliveira Ferreira da Mata, João Marcelo de Castro e Sousa, Joaquim Soares da Costa Junior, Hercília Maria Lins Rolim, Arnobio Antonio da Silva-Junior & Ana Amélia de Carvalho Melo-Cavalcante. (2017) Evaluation of toxic, cytotoxic and genotoxic effects of phytol and its nanoemulsion. Chemosphere 177, pages 93-101.
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Mateusz Maciejczyk, Bozena Mikoluc, Barbara Pietrucha, Edyta Heropolitanska - Pliszka, Malgorzata Pac, Radosław Motkowski & Halina Car. (2017) Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome. Redox Biology 11, pages 375-383.
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Yosef Shiloh & Howard M. Lederman. (2017) Ataxia-telangiectasia (A-T): An emerging dimension of premature ageing. Ageing Research Reviews 33, pages 76-88.
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Sara Biagiotti, Michele Menotta, Sara Orazi, Chiara Spapperi, Serena Brundu, Alessandra Fraternale, Marzia Bianchi, Luigia Rossi, Luciana Chessa & Mauro Magnani. (2016) Dexamethasone improves redox state in ataxia telangiectasia cells by promoting an NRF2‐mediated antioxidant response. The FEBS Journal 283:21, pages 3962-3978.
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Andrew Campbell, Brittany Krupp, Jared Bushman, Mark Noble, Christoph Pröschel & Margot Mayer-Pröschel. (2015) A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden. Human Molecular Genetics 24:22, pages 6331-6349.
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Stefania Squadrone, Paola Brizio, Cecilia Mancini, Elisa Pozzi, Simona Cavalieri, Maria Cesarina Abete & Alfredo Brusco. (2015) Blood metal levels and related antioxidant enzyme activities in patients with ataxia telangiectasia. Neurobiology of Disease 81, pages 162-167.
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Merve Alpay, Lindsey R. F. Backman, Xiaodong Cheng, Muzaffer Dukel, Wan-Ju Kim, Lingbao Ai & Kevin D. Brown. (2015) Oxidative stress shapes breast cancer phenotype through chronic activation of ATM-dependent signaling. Breast Cancer Research and Treatment 151:1, pages 75-87.
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Yolandi Espach, Amanda Lochner, Hans Strijdom & Barbara Huisamen. (2015) ATM Protein Kinase Signaling, Type 2 Diabetes and Cardiovascular Disease. Cardiovascular Drugs and Therapy 29:1, pages 51-58.
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R. da Silva, E.C. dos Santos-Valente, F. Burim Scomparini, R.O. Saccardo Sarni & B.T. Costa-Carvalho. (2014) The relationship between nutritional status, vitamin A and zinc levels and oxidative stress in patients with ataxia-telangiectasia. Allergologia et Immunopathologia 42:4, pages 329-335.
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Brahma B. Panda, V. Mohan M. Achary, Srikrishna Mahanty & Kamal K. Panda. 2013. Climate Change and Plant Abiotic Stress Tolerance. Climate Change and Plant Abiotic Stress Tolerance 251 294 .
Saijun Fan, Qinghui MengJiaying XuYang JiaoLin ZhaoXiaodong Zhang, Fazlul H. Sarkar, Milton L. BrownAnatoly Dritschilo & Eliot M. Rosen. (2013) DIM (3,3′-diindolylmethane) confers protection against ionizing radiation by a unique mechanism. Proceedings of the National Academy of Sciences 110:46, pages 18650-18655.
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Sam Nayler, Magtouf Gatei, Sergei Kozlov, Richard Gatti, Jessica C. Mar, Christine A. Wells, Martin Lavin & Ernst Wolvetang. (2012) Induced Pluripotent Stem Cells from Ataxia-Telangiectasia Recapitulate the Cellular Phenotype. Stem Cells Translational Medicine 1:7, pages 523-535.
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Michal Kirshner, Ronit Galron, Dan Frenkel, Gil Mandelbaum, Yosef Shiloh, Zhao-Qi Wang & Ari Barzilai. (2011) Malfunctioning DNA Damage Response (DDR) Leads to the Degeneration of Nigro-Striatal Pathway in Mouse Brain. Journal of Molecular Neuroscience 46:3, pages 554-568.
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Giovanni Pagano, Annarita Aiello Talamanca, Giuseppe Castello, Federico V. Pallardó, Adriana Zatterale & Paolo Degan. (2012) Oxidative stress in Fanconi anaemia: from cells and molecules towards prospects in clinical management. Biological Chemistry 393:1-2, pages 11-21.
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Malgorzata Miller, Annette Dreisbach, Andreas Otto, Dörte Becher, Jörg Bernhardt, Michael Hecker, Maikel P. Peppelenbosch & Jan Maarten van Dijl. (2011) Mapping of Interactions between Human Macrophages and Staphylococcus aureus Reveals an Involvement of MAP Kinase Signaling in the Host Defense . Journal of Proteome Research 10:9, pages 4018-4032.
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Dorit Raz-Prag, Ronit Galron, Niva Segev-Amzaleg, Arieh S. Solomon, Yosef Shiloh, Ari Barzilai & Dan Frenkel. (2011) A Role for Vascular Deficiency in Retinal Pathology in a Mouse Model of Ataxia-Telangiectasia. The American Journal of Pathology 179:3, pages 1533-1541.
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Michaela Semlitsch, Rodney E. Shackelford, Sandra Zirkl, Wolfgang Sattler & Ernst Malle. (2011) ATM protects against oxidative stress induced by oxidized low-density lipoprotein. DNA Repair 10:8, pages 848-860.
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Inbal Dar, Galit Yosha, Ronen Elfassy, Ronit Galron, Zhao-Qi Wang, Yosef Shiloh & Ari Barzilai. (2011) Investigation of the Functional Link between ATM and NBS1 in the DNA Damage Response in the Mouse Cerebellum. Journal of Biological Chemistry 286:17, pages 15361-15376.
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Jeesun Kim & Paul K.Y. Wong. (2009) Loss of ATM Impairs Proliferation of Neural Stem Cells Through Oxidative Stress-Mediated p38 MAPK Signaling. Stem Cells 27:8, pages 1987-1998.
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Jeesun Kim & Paul K.Y. Wong. (2009) Oxidative Stress Is Linked to ERK1/2-p16 Signaling-mediated Growth Defect in ATM-deficient Astrocytes. Journal of Biological Chemistry 284:21, pages 14396-14404.
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Lucia Migliore & Fabio Coppedè. (2009) Environmental-induced oxidative stress in neurodegenerative disorders and aging. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 674:1-2, pages 73-84.
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Shuji Kishi, Peter E. Bayliss, Junzo Uchiyama, Eriko Koshimizu, Jie Qi, Purushothama Nanjappa, Shintaro Imamura, Asiful Islam, Donna Neuberg, Adam Amsterdam & Thomas M. Roberts. (2008) The Identification of Zebrafish Mutants Showing Alterations in Senescence-Associated Biomarkers. PLoS Genetics 4:8, pages e1000152.
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Sharon Biton, Ari Barzilai & Yosef Shiloh. (2008) The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle. DNA Repair 7:7, pages 1028-1038.
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Stacey A. Rimkus, Rebeccah J. Katzenberger, Anthony T. Trinh, Gerald E. Dodson, Randal S. Tibbetts & David A. Wassarman. (2008) Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia . Genes & Development 22:9, pages 1205-1220.
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Sundari Chodavarapu, Ruben Gomez, Matias Vicente & Jon M. Kaguni. (2008) Escherichia coli Dps interacts with DnaA protein to impede initiation: a model of adaptive mutation. Molecular Microbiology 67:6, pages 1331-1346.
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Ana Lloret, Rita Calzone, Christina Dunster, Paola Manini, Marco d'Ischia, Paolo Degan, Frank J. Kelly, Federico V. Pallardó, Adriana Zatterale & Giovanni Pagano. (2008) Different patterns of in vivo pro-oxidant states in a set of cancer- or aging-related genetic diseases. Free Radical Biology and Medicine 44:4, pages 495-503.
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Yaniv Assaf, Ronit Galron, Itai Shapira, Anat Nitzan, Tamar Blumenfeld-Katzir, Arieh S. Solomon, Vered Holdengreber, Zhao-Qi Wang, Yosef Shiloh & Ari Barzilai. (2008) MRI evidence of white matter damage in a mouse model of Nijmegen breakage syndrome. Experimental Neurology 209:1, pages 181-191.
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Paolo Degan, Marco d'Ischia, Federico V. Pallardó, Adriana Zatterale, Alfredo Brusco, Rita Calzone, Simona Cavalieri, Kaan Kavaklı, Ana Lloret, Paola Manini, Maria Antonietta Pisanti, Emilia Vuttariello & Giovanni Pagano. (2007) Glutathione levels in blood from ataxia telangiectasia patients suggest in vivo adaptive mechanisms to oxidative stress. Clinical Biochemistry 40:9-10, pages 666-670.
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Brett C. Langley. 2007. Oxidative Stress and Neurodegenerative Disorders. Oxidative Stress and Neurodegenerative Disorders 165 182 .
Kazi M. Ahmed, Shaozhong Dong, Ming Fan & Jian Jian Li. (2006) Nuclear Factor-κB p65 Inhibits Mitogen-Activated Protein Kinase Signaling Pathway in Radioresistant Breast Cancer Cells. Molecular Cancer Research 4:12, pages 945-955.
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Zhiwan Dong & Alan E. Tomkinson. (2006) ATM mediates oxidative stress-induced dephosphorylation of DNA ligase IIIα. Nucleic Acids Research 34:20, pages 5721-5279.
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Nuri Gueven, John Luff, Cheng Peng, Kazuyuki Hosokawa, Steven E. Bottle & Martin F. Lavin. (2006) Dramatic extension of tumor latency and correction of neurobehavioral phenotype in Atm-mutant mice with a nitroxide antioxidant. Free Radical Biology and Medicine 41:6, pages 992-1000.
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Susan M. Kraemer, David A. Goldstrohm, Ann Berger, Susan Hankey, Sherry A. Rovinsky, W. Scott Moye-Rowley & Laurie A. Stargell. (2006) TFIIA Plays a Role in the Response to Oxidative Stress. Eukaryotic Cell 5:7, pages 1081-1090.
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Xianghong Kuang, Mingshan Yan, Na Liu, Virginia L. Scofield, Wenan Qiang, Jodi Cahill, Williams S. Lynn & Paul K. Y. Wong. (2004) Control of Atm?/? thymic lymphoma cell proliferation in vitro and in vivo by dexamethasone. Cancer Chemotherapy and Pharmacology 55:3, pages 203-212.
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