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Redox Report
Communications in Free Radical Research
Volume 10, 2005 - Issue 2
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Research Articles

Antiodidant activity of thiosulfinates derived from garlic

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Pages 96-102 | Published online: 19 Jul 2013

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Shamasoddin Shekh, Smriti Moi & Konkallu Hanumae Gowd. (2023) Virtual screening of sulfur compounds of Allium against coronavirus proteases: E-Ajoene is a potential dual protease targeting covalent inhibitor. Journal of Sulfur Chemistry 44:1, pages 74-89.
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Marya Aziz & Salwa Karboune. (2018) Natural antimicrobial/antioxidant agents in meat and poultry products as well as fruits and vegetables: A review. Critical Reviews in Food Science and Nutrition 58:3, pages 486-511.
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Jackie Yan-Yan Chan, Hei-Tung Tsui, Ivan Ying-Ming Chung, Robbie Yat-Kan Chan, Yiu-Wa Kwan & Shun-Wan Chan. (2014) Allicin protects rat cardiomyoblasts (H9c2 cells) from hydrogen peroxide-induced oxidative injury through inhibiting the generation of intracellular reactive oxygen species. International Journal of Food Sciences and Nutrition 65:7, pages 868-873.
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Articles from other publishers (56)

Kalyani Pathak, Manash Pratim Pathak, Riya Saikia, Urvashee Gogoi, Jon Jyoti Sahariah, Aparoop Das, Mohammad Zaki Ahmad, Tirna Paul, Jyotirmoy Das & Saif Aboud M. Alqahtani. (2024) Cardioprotective Activities of some Indian Spices: An Insight into Pharmacology and Phytochemical Investigation. Current Traditional Medicine 10:1.
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Yara Atef, Keita Kinoshita, Yusei Ichihara, Keisuke Ushida, Yuma Hirata, Yuki Kurauchi, Takahiro Seki & Hiroshi Katsuki. (2023) Therapeutic effect of allicin in a mouse model of intracerebral hemorrhage. Journal of Pharmacological Sciences 153:4, pages 208-214.
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Vivek D. Savairam, Neha A. Patil, Shrikant R. Borate, Mahesh M. Ghaisas & Rajkumar V. Shete. (2023) Evaluation of antiepileptic activity of ethanolic extract of garlic containing 3.25% allicin in experimental animals. Pharmacological Research - Modern Chinese Medicine 8, pages 100289.
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Vivek D. Savairam, Neha A. Patil, Shrikant R. Borate, Mahesh M. Ghaisas & Rajkumar V. Shete. (2023) Allicin: A review of its important pharmacological activities. Pharmacological Research - Modern Chinese Medicine 8, pages 100283.
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Burhan CEYLAN & Gizem TİRİS. (2023) Development of a New HPLC Method for the Identification of Allicin and S-allyl Cysteine in Garlic (<i>Allium sativum L.</i>) Extracts. Bezmialem Science 11:2, pages 195-199.
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Judita Lidiková, Natália Čeryová, Tomáš Tóth, Janette Musilová, Alena Vollmannová, Kushvara Mammadova & Eva Ivanišová. 2023. Herbs and Spices - New Advances. Herbs and Spices - New Advances.
Şükriye ÇAKMAK & Muhammet ÇAVUŞ. (2023) Novel Bis-1,3,4-Thiadiazoles Derivatives: Synthesis, Spectroscopic Characterization, DFT Calculations and Evaluation of their Antimicrobial and Antioxidant Activities. Cumhuriyet Science Journal 44:1, pages 81-89.
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Debarati Rakshit, Sudipta Nayak, Snehashis Kundu, Efthalia Angelopoulou, Efstratios-Stylianos Pyrgelis, Christina Piperi & Awanish Mishra. (2023) The Pharmacological Activity of Garlic ( Allium sativum ) in Parkinson’s Disease: From Molecular Mechanisms to the Therapeutic Potential . ACS Chemical Neuroscience 14:6, pages 1033-1044.
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Vytória Piscitelli Cavalcanti, Smail Aazza, Suzan Kelly Vilela Bertolucci, João Pedro Miranda Rocha, Adriane Duarte Coelho, Altino Júnior Mendes Oliveira, Laís Campelo Mendes, Maysa Mathias Alves Pereira, Ludmila Caproni Morais, Moacir Rossi Forim, Moacir Pasqual & Joyce Dória. (2021) Solvent Mixture Optimization in the Extraction of Bioactive Compounds and Antioxidant Activities from Garlic (Allium sativum L.). Molecules 26:19, pages 6026.
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Sumeyra Cetinkaya & Ipek Süntar. 2021. Nutraceuticals and Cancer Signaling. Nutraceuticals and Cancer Signaling 259 289 .
Vytória Piscitelli Cavalcanti, Smail Aazza, Suzan Kelly Vilela Bertolucci, Maysa Mathias Alves Pereira, Pórtya Piscitelli Cavalcanti, Victor Hugo Teixeira Buttrós, Ana Mara de Oliveira e Silva, Moacir Pasqual & Joyce Dória. (2020) Plant, pathogen and biocontrol agent interaction effects on bioactive compounds and antioxidant activity in garlic. Physiological and Molecular Plant Pathology 112, pages 101550.
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Chetan Rajak, Neelu Singh & Poonam Parashar. (2020) Metal toxicity and natural antidotes: prevention is better than cure. Environmental Science and Pollution Research 27:35, pages 43582-43598.
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Hui Jiang, Zheng Xing, Yang Wang, Zhaoli Zhang, Benjamin Kumah Mintah, Mokhtar Dabbour, Yihe Li, Ronghai He, Liurong Huang & Haile Ma. (2020) Preparation of allicin-whey protein isolate conjugates: Allicin extraction by water, conjugates’ ultrasound-assisted binding and its stability, solubility and emulsibility analysis. Ultrasonics Sonochemistry 63, pages 104981.
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Lorena Martínez, Sisse Jongberg, Gaspar Ros, Leif H. Skibsted & Gema Nieto. (2020) Plant derived ingredients rich in nitrates or phenolics for protection of pork against protein oxidation. Food Research International 129, pages 108789.
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Sahar Hassan Orabi, Doaa Abd Eldaium, Azza Hassan, Hesham Saad El Sabagh & Mabrouk Attia Abd Eldaim. (2020) Allicin modulates diclofenac sodium induced hepatonephro toxicity in rats via reducing oxidative stress and caspase 3 protein expression. Environmental Toxicology and Pharmacology 74, pages 103306.
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Wanassanun Pannangrong, Jariya Umka Welbat, Amnard Chaichun & Bungorn Sripanidkulchai. (2020) Effect of combined extracts of aged garlic, ginger, and chili peppers on cognitive performance and brain antioxidant markers in Aβ-induced rats. Experimental Animals 69:3, pages 269-278.
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Javad Sharifi-Rad, Nathália Cristina Cirone Silva, Arvind Jantwal, Indra D. Bhatt, Farukh Sharopov, William C. Cho, Yasaman Taheri & Natália Martins. (2019) Therapeutic Potential of Allicin-Rich Garlic Preparations: Emphasis on Clinical Evidence toward Upcoming Drugs Formulation. Applied Sciences 9:24, pages 5555.
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Khairan Khairan, Lalla Aïcha Ba, Torsten Burkholz, Michaela Leroch, Matthias Hahn, Tanya Schwab, Markus Klotz, Karl-Herbert Schaefer & Claus Jacob. (2019) Electrochemical Potential-Biological Activity Relationships of Cyclic Sulfur-Containing Molecules Against Steinernema feltiae, Botrytis cinerea, and Neuro 2a Cell Line. Current Pharmacology Reports 5:3, pages 174-187.
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Cecilia Nwadiuto Amadi, Samuel James Offor, Chiara Frazzoli & Orish Ebere Orisakwe. (2019) Natural antidotes and management of metal toxicity. Environmental Science and Pollution Research 26:18, pages 18032-18052.
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Bahare Salehi, Paolo Zucca, Ilkay Erdogan Orhan, Elena Azzini, Charles Oluwaseun Adetunji, Soheb Anwar Mohammed, Sanjay K. Banerjee, Farukh Sharopov, Daniela Rigano, Javad Sharifi-Rad, Lorene Armstrong, Miquel Martorell, Antoni Sureda, Natália Martins, Zeliha Selamoğlu & Zaheer Ahmad. (2019) Allicin and health: A comprehensive review. Trends in Food Science & Technology 86, pages 502-516.
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Parvej Ahmad, Sahir Sultan Alvi & M. Salman Khan. 2019. Natural Bio-active Compounds. Natural Bio-active Compounds 561 585 .
Kensuke Seki, Junya Ishikawa & Youji Okada. (2018) Contribution of 2-Propenesulfenic Acid to the Antioxidant Activity of Allicin. Journal of Food Science 83:5, pages 1265-1270.
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Yue-E Sun & Weidong Wang. (2017) Changes in nutritional and bio-functional compounds and antioxidant capacity during black garlic processing. Journal of Food Science and Technology 55:2, pages 479-488.
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Je-Won Ko, Sung-Hyeuk Park, Na-Rae Shin, Jin-Young Shin, Jeong-Won Kim, In-Sik Shin, Changjong Moon, Jeong-Doo Heo, Jong-Choon Kim & In-Chul Lee. (2017) Protective effect and mechanism of action of diallyl disulfide against acetaminophen-induced acute hepatotoxicity. Food and Chemical Toxicology 109, pages 28-37.
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Hugo Becerril-Chávez, Ana Laura Colín-González, Juana Villeda-Hernández, Sonia Galván-Arzate, Anahí Chavarría, María Eduarda de Lima, Isaac Túnez & Abel Santamaría. (2017) Protective effects of S-allyl cysteine on behavioral, morphological and biochemical alterations in rats subjected to chronic restraint stress: Antioxidant and anxiolytic effects. Journal of Functional Foods 35, pages 105-114.
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Ezgi Doğan Cömert & Vural Gökmen. (2017) Antioxidants Bound to an Insoluble Food Matrix: Their Analysis, Regeneration Behavior, and Physiological Importance. Comprehensive Reviews in Food Science and Food Safety 16:3, pages 382-399.
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E. Bravi, O. Marconi, V. Sileoni, M. R. Rollo & G. Perretti. (2016) Antioxidant effects of supercritical fluid garlic extracts in canned artichokes. Journal of Food Science and Technology 53:10, pages 3744-3751.
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Ali-Reza Ebrahimzadeh-Bideskan, Javad Hami, Fatemeh Alipour, Hossein Haghir, Ali-Reza Fazel & Akram Sadeghi. (2016) Protective effects of ascorbic acid and garlic extract against lead-induced apoptosis in developing rat hippocampus. Metabolic Brain Disease 31:5, pages 1123-1132.
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Abiodun Olusoji Owoade, Adewale Adetutu & Olubukola Sinbad Olorunnisola. (2016) Influence of Polyphenolic Contents on the Antioxidant Properties of <i>Hibiscus sabdariffa</i> Extract (HSE), Aged Garlic Extract (AGE) and Garlic Tablet (GT) <i>in Vitro</i>. Food and Nutrition Sciences 07:06, pages 417-428.
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Chun-Hao Huang, Fang-Yu Hsu, Yuan-Heng Wu, Linda Zhong, Mu-Yun Tseng, Chao-Jen Kuo, Ao-Lin Hsu, Shih-Shin Liang & Shyh-Horng Chiou. (2015) Analysis of lifespan-promoting effect of garlic extract by an integrated metabolo-proteomics approach. The Journal of Nutritional Biochemistry 26:8, pages 808-817.
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Jie Tian, Fangling Jiang & Zhen Wu. (2014) The apoplastic oxidative burst as a key factor of hyperhydricity in garlic plantlet in vitro. Plant Cell, Tissue and Organ Culture (PCTOC) 120:2, pages 571-584.
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Shu-Guang Liu, Peng-Yu Ren, Guo-Yu Wang, Shu-Xin Yao & Xi-Jing He. (2015) Allicin protects spinal cord neurons from glutamate-induced oxidative stress through regulating the heat shock protein 70/inducible nitric oxide synthase pathway. Food & Function 6:1, pages 320-329.
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Fatemeh Alipour, Alireza Ebrahimzaheh Bideskan, Alireza Fazel, Akram Sadeghi, Javad Hami, Hamed Kheradmand & Hossein Haghir. (2014) Protective effects of ascorbic acid and garlic extract against neurogenesis inhibition caused by developmental lead exposure in the dentate gyrus of rat. Comparative Clinical Pathology 23:6, pages 1681-1687.
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Keith U. Ingold & Derek A. Pratt. (2014) Advances in Radical-Trapping Antioxidant Chemistry in the 21st Century: A Kinetics and Mechanisms Perspective. Chemical Reviews 114:18, pages 9022-9046.
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Bożena Muszyńska, Anna Maślanka, Katarzyna Sułkowska-Ziaja, Włodzimierz Opoka & Agnieszka Szopa. (2014) Analysis of 5-Methyltryptamine, L -Tryptophan, 5-Hydroxy- L -Tryptophan, and Melatonin in the Bulbs of Garlic by Thin-Layer Chromatographic Method Coupled with Densitometric Detection . Journal of Planar Chromatography – Modern TLC 27:3, pages 210-216.
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Nihar R. Jena, Neha Agnihotri & Phool C. Mishra. 2014. Application of Computational Techniques in Pharmacy and Medicine. Application of Computational Techniques in Pharmacy and Medicine 59 94 .
Ji Hee Jeong, Hee Rok Jeong, Yu Na Jo, Hyeon Ju Kim, Jeong Hae Shin & Ho Jin Heo. (2013) Ameliorating effects of aged garlic extracts against Aβ-induced neurotoxicity and cognitive impairment. BMC Complementary and Alternative Medicine 13:1.
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Jackie Yan-Yan Chan, Ailsa Chui-Ying Yuen, Robbie Yat-Kan Chan & Shun-Wan Chan. (2013) A Review of the Cardiovascular Benefits and Antioxidant Properties of Allicin. Phytotherapy Research 27:5, pages 637-646.
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Davar Shahsavani, Hasan Baghshani, Mohammad Reza Aslani & Fatemeh Sadat Fatemi. (2010) The impact of allicin on lead-induced oxidative damage in selected organs of the common carp (Cyprinus carpio). Comparative Clinical Pathology 21:5, pages 769-775.
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Lulu Zhang, Huanjie Zhang, Yutian Miao, Sijia Wu, Haiqing Ye & Yuan Yuan. (2012) Protective effect of allicin against acrylamide-induced hepatocyte damage in vitro and in vivo. Food and Chemical Toxicology 50:9, pages 3306-3312.
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Riccardo Amorati, Philip T. Lynett, Luca Valgimigli & Derek A. Pratt. (2012) The Reaction of Sulfenic Acids with Peroxyl Radicals: Insights into the Radical‐Trapping Antioxidant Activity of Plant‐Derived Thiosulfinates. Chemistry – A European Journal 18:20, pages 6370-6379.
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Philip T. Lynett, Krista Butts, Vipraja Vaidya, Graham E. Garrett & Derek A. Pratt. (2011) The mechanism of radical-trapping antioxidant activity of plant-derived thiosulfinates. Organic & Biomolecular Chemistry 9:9, pages 3320.
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Veena Sharma, Arti Sharma & Leena Kansal. (2010) The effect of oral administration of Allium sativum extracts on lead nitrate induced toxicity in male mice. Food and Chemical Toxicology 48:3, pages 928-936.
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Vipraja Vaidya, Keith U. Ingold & Derek A. Pratt. (2008) Garlic: Source of the Ultimate Antioxidants—Sulfenic Acids. Angewandte Chemie International Edition 48:1, pages 157-160.
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Vipraja Vaidya, Keith U. Ingold & Derek A. Pratt. (2009) Garlic: Source of the Ultimate Antioxidants-Sulfenic Acids. Angewandte Chemie 121:1, pages 163-166.
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Rajdeep Chowdhury, Abhishek Dutta, Susri Ray Chaudhuri, Nilendu Sharma, Ashok K. Giri & Keya Chaudhuri. (2008) In vitro and in vivo reduction of sodium arsenite induced toxicity by aqueous garlic extract. Food and Chemical Toxicology 46:2, pages 740-751.
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José Pedraza-Chaverri, Paola Yam-Canul, Yolanda I Chirino, Dolores Javier Sánchez-González, Claudia María Martínez-Martínez, Cristino Cruz & Omar N Medina-Campos. (2008) Protective effects of garlic powder against potassium dichromate-induced oxidative stress and nephrotoxicity. Food and Chemical Toxicology 46:2, pages 619-627.
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Riccardo Amorati & Gian Franco Pedulli. (2008) Do garlic-derived allyl sulfides scavenge peroxyl radicals?. Organic & Biomolecular Chemistry 6:6, pages 1103.
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Youji Okada, Kaoru Tanaka, Eisuke Sato & Haruo Okajima. (2008) Antioxidant activity of the new thiosulfinate derivative, S-benzyl phenylmethanethiosulfinate, from Petiveria alliacea L.. Organic & Biomolecular Chemistry 6:6, pages 1097.
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Mukesh Kumar Agarwal, Mohammad Iqbal & Mohammad Athar. (2007) Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: Implications for cancer prevention. Food and Chemical Toxicology 45:9, pages 1634-1640.
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