187
Views
61
CrossRef citations to date
0
Altmetric
Short Refereed Papers

Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells

, &
Pages 101-106 | Published online: 19 Jul 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Robert M. Jackson & Chhavi Gupta. (2010) Hypoxia and kinase activity regulate lung epithelial cell glutathione. Experimental Lung Research 36:1, pages 45-56.
Read now

Articles from other publishers (59)

Lukas S. Wijaya, Carina Rau, Theresa S. Braun, Serif Marangoz, Vincent Spegg, Matthijs Vlasveld, Wiebke Albrecht, Tim Brecklinghaus, Hennicke Kamp, Joost B. Beltman, Jan G. Hengstler, Bob van de Water, Marcel Leist & Stefan Schildknecht. (2021) Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes. Cell Biology and Toxicology 38:5, pages 847-864.
Crossref
Agnieszka Ścibior, Iwona Wojda, Ewa Wnuk, Łukasz Pietrzyk & Zbigniew Plewa. (2021) Response of Cytoprotective and Detoxifying Proteins to Vanadate and/or Magnesium in the Rat Liver: The Nrf2-Keap1 System. Oxidative Medicine and Cellular Longevity 2021, pages 1-15.
Crossref
Bożena Gabryel & Klaudia Bontor. (2021) Ligaza γ-glutamylocysteiny – od molekularnych mechanizmów regulacji aktywności enzymatycznej do implikacji terapeutycznych. Postępy Higieny i Medycyny Doświadczalnej 75:1, pages 823-836.
Crossref
Hyungsun Park, Jongyoon Kim, Chihoon Shin & Seongju Lee. (2021) Intersection between Redox Homeostasis and Autophagy: Valuable Insights into Neurodegeneration. Antioxidants 10:5, pages 694.
Crossref
Hongqiao Zhang, Todd E. Morgan & Henry Jay Forman. (2021) Age-related alteration in HNE elimination enzymes. Archives of Biochemistry and Biophysics 699, pages 108749.
Crossref
Marcus J. C. Long, Chloé Rogg & Yimon Aye. (2020) An Oculus to Profile and Probe Target Engagement In Vivo: How T-REX Was Born and Its Evolution into G-REX. Accounts of Chemical Research 54:3, pages 618-631.
Crossref
Tuo Yang, Yang Sun, Qianqian Li, Senmiao Li, Yejie Shi, Rehana K. Leak, Jun Chen & Feng Zhang. (2020) Ischemic preconditioning provides long-lasting neuroprotection against ischemic stroke: The role of Nrf2. Experimental Neurology 325, pages 113142.
Crossref
Elena Piccinin, Simon Ducheix, Claudia Peres, Maria Arconzo, Maria Carmela Vegliante, Anna Ferretta, Elena Bellafante, Gaetano Villani & Antonio Moschetta. (2019) PGC-1β Induces Susceptibility To Acetaminophen-Driven Acute Liver Failure. Scientific Reports 9:1.
Crossref
Meng Wang, Lu Qiu, Xufang Ru, Yijiang Song & Yiguo Zhang. (2019) Distinct isoforms of Nrf1 diversely regulate different subsets of its cognate target genes. Scientific Reports 9:1.
Crossref
Ashish Saxena, Himangshu Sonowal & Kota V. Ramana. 2019. The Molecular Nutrition of Fats. The Molecular Nutrition of Fats 419 431 .
Wiramon Rungratanawanich, Maurizio Memo & Daniela Uberti. (2018) Redox Homeostasis and Natural Dietary Compounds: Focusing on Antioxidants of Rice (Oryza sativa L.). Nutrients 10:11, pages 1605.
Crossref
Hongqiao Zhang, Honglei Liu, Lulu Zhou, Jenay Yuen & Henry Jay Forman. (2017) Temporal changes in glutathione biosynthesis during the lipopolysaccharide-induced inflammatory response of THP-1 macrophages. Free Radical Biology and Medicine 113, pages 304-310.
Crossref
Françoise Guéraud. (2017) 4-Hydroxynonenal metabolites and adducts in pre-carcinogenic conditions and cancer. Free Radical Biology and Medicine 111, pages 196-208.
Crossref
Wojciech Łuczaj, Agnieszka Gęgotek & Elżbieta Skrzydlewska. (2017) Antioxidants and HNE in redox homeostasis. Free Radical Biology and Medicine 111, pages 87-101.
Crossref
Hongqiao Zhang & Henry Jay Forman. (2017) 4-hydroxynonenal-mediated signaling and aging. Free Radical Biology and Medicine 111, pages 219-225.
Crossref
Hongqiao Zhang, Lulu Zhou, Jenay Yuen, Nancy Birkner, Valerie Leppert, Peggy A. O’Day & Henry Jay Forman. (2017) Delayed Nrf2-regulated antioxidant gene induction in response to silica nanoparticles. Free Radical Biology and Medicine 108, pages 311-319.
Crossref
Hongqiao Zhang & Henry Jay Forman. (2017) Signaling by 4-hydroxy-2-nonenal: Exposure protocols, target selectivity and degradation. Archives of Biochemistry and Biophysics 617, pages 145-154.
Crossref
Fulvio Ursini, Matilde Maiorino & Henry Jay Forman. (2016) Redox homeostasis: The Golden Mean of healthy living. Redox Biology 8, pages 205-215.
Crossref
Henry Jay Forman. (2016) Redox signaling: An evolution from free radicals to aging. Free Radical Biology and Medicine 97, pages 398-407.
Crossref
Jianguo Lin & Anping Chen. (2016) Perilipin 5 restores the formation of lipid droplets in activated hepatic stellate cells and inhibits their activation. Laboratory Investigation 96:7, pages 791-806.
Crossref
Shobha M. Swamy, Namakkal S. Rajasekaran & Victor J. Thannickal. (2016) Nuclear Factor–Erythroid-2–Related Factor 2 in Aging and Lung Fibrosis. The American Journal of Pathology 186:7, pages 1712-1723.
Crossref
Gavin Ferguson & Wallace Bridge. (2016) Glutamate cysteine ligase and the age-related decline in cellular glutathione: The therapeutic potential of γ-glutamylcysteine. Archives of Biochemistry and Biophysics 593, pages 12-23.
Crossref
Hongqiao Zhang, Kelvin J.A. Davies & Henry Jay Forman. (2015) Oxidative stress response and Nrf2 signaling in aging. Free Radical Biology and Medicine 88, pages 314-336.
Crossref
Françoise Guéraud. 2015. Lipid Oxidation in Health and Disease. Lipid Oxidation in Health and Disease 387 404 .
Norsyahida Mohd Fauzi & Corinne M. Spickett. 2015. Studies on Experimental Toxicology and Pharmacology. Studies on Experimental Toxicology and Pharmacology 43 79 .
Angelos K. Sikalidis, Kevin M. Mazor, Jeong-In Lee, Heather B. Roman, Lawrence L. Hirschberger & Martha H. Stipanuk. (2014) Upregulation of capacity for glutathione synthesis in response to amino acid deprivation: regulation of glutamate–cysteine ligase subunits. Amino Acids 46:5, pages 1285-1296.
Crossref
Giancarlo Aldini, Marina Carini, Kyung-Jin Yeum & Giulio Vistoli. (2014) Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: toward the discovery of a novel class of bioactive compounds. Free Radical Biology and Medicine 69, pages 145-156.
Crossref
Antonio Ayala, Mario F. Muñoz & Sandro Argüelles. (2014) Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal. Oxidative Medicine and Cellular Longevity 2014, pages 1-31.
Crossref
Sean S. Davies & Lilu Guo. 2013. Molecular Basis of Oxidative Stress. Molecular Basis of Oxidative Stress 49 70 .
Shelly C. Lu. (2013) Glutathione synthesis. Biochimica et Biophysica Acta (BBA) - General Subjects 1830:5, pages 3143-3153.
Crossref
Nikolai L. Chepelev, Hongqiao Zhang, Honglei Liu, Skye McBride, Andrew J. Seal, Todd E. Morgan, Caleb E. Finch, William G. Willmore, Kelvin J.A. Davies & Henry Jay Forman. (2013) Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction. Redox Biology 1:1, pages 183-189.
Crossref
Hongqiao Zhang & Henry Jay Forman. (2012) Glutathione synthesis and its role in redox signaling. Seminars in Cell & Developmental Biology 23:7, pages 722-728.
Crossref
Sunny O. Abarikwu, Aditya B. Pant & Ebenezer O. Farombi. (2011) 4‐Hydroxynonenal Induces Mitochondrial‐Mediated Apoptosis and Oxidative Stress in SH‐SY5Y Human Neuronal Cells. Basic & Clinical Pharmacology & Toxicology 110:5, pages 441-448.
Crossref
Hongqiao Zhang, Honglei Liu, Kelvin J.A. Davies, Constantinos Sioutas, Caleb E. Finch, Todd E. Morgan & Henry Jay Forman. (2012) Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments. Free Radical Biology and Medicine 52:9, pages 2038-2046.
Crossref
MA Siddiqui, V Kumar, MP Kashyap, M Agarwal, AK Singh, S Jahan, VK Khanna, AA Al-Khedhairy, J Musarrat & AB Pant. (2012) Short-term exposure of 4-hydroxynonenal induces mitochondria-mediated apoptosis in PC12 cells. Human & Experimental Toxicology 31:4, pages 336-345.
Crossref
Wei Li, Carmina Busu, Magdalena L. Circu & Tak Yee Aw. (2012) Glutathione in Cerebral Microvascular Endothelial Biology and Pathobiology: Implications for Brain Homeostasis. International Journal of Cell Biology 2012, pages 1-14.
Crossref
Christopher M. Mahaffey, Nichole C. Mahaffey, William Holland, Hongqiao Zhang, David R. Gandara, Philip C. Mack & Henry Jay Forman. (2012) Aberrant Regulation of the MRP3 Gene in Non-small Cell Lung Carcinoma. Journal of Thoracic Oncology 7:1, pages 34-39.
Crossref
Qing-Ning Liang, Yu-Chen Sheng, Ping Jiang, Li-Li Ji, Yu-Ye Xia, Yang Min & Zheng-Tao Wang. (2011) The difference of glutathione antioxidant system in newly weaned and young mice liver and its involvement in isoline-induced hepatotoxicity. Archives of Toxicology 85:10, pages 1267-1279.
Crossref
Piotr Zimniak. (2011) Relationship of electrophilic stress to aging. Free Radical Biology and Medicine 51:6, pages 1087-1105.
Crossref
Yu. K. Karaman, T. P. Novgorodtseva & N. V. Zhukova. (2011) Phospholipid Composition of Erythrocytes and Glutathione Redox System in Rats during Adaptation to Cholesterol Load. Bulletin of Experimental Biology and Medicine 150:3, pages 291-294.
Crossref
M.A. Siddiqui, M.P. Kashyap, V. Kumar, A.A. Al-Khedhairy, J. Musarrat & A.B. Pant. (2010) Protective potential of trans-resveratrol against 4-hydroxynonenal induced damage in PC12 cells. Toxicology in Vitro 24:6, pages 1592-1598.
Crossref
Henry Jay Forman. (2010) Reactive oxygen species and α,β-unsaturated aldehydes as second messengers in signal transduction. Annals of the New York Academy of Sciences 1203:1, pages 35-44.
Crossref
Hongqiao Zhang & Henry Jay Forman. (2010) Reexamination of the electrophile response element sequences and context reveals a lack of consensus in gene function. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1799:7, pages 496-501.
Crossref
S. P. Singh, M. Niemczyk, D. Saini, V. Sadovov, L. Zimniak & P. Zimniak. (2009) Disruption of the mGsta4 Gene Increases Life Span of C57BL Mice. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 65A:1, pages 14-23.
Crossref
Ian M. Copple, Christopher E. Goldring, Neil R. Kitteringham & B. Kevin Park. 2010. Adverse Drug Reactions. Adverse Drug Reactions 233 266 .
V. I. Kulinsky & L. S. Kolesnichenko. (2009) The glutathione system. I. Synthesis, transport, glutathione transferases, glutathione peroxidases. Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 3:2, pages 129-144.
Crossref
Christopher M. Mahaffey, Hongqiao Zhang, Alessandra Rinna, William Holland, Philip C. Mack & Henry Jay Forman. (2009) Multidrug-resistant protein-3 gene regulation by the transcription factor Nrf2 in human bronchial epithelial and non-small-cell lung carcinoma. Free Radical Biology and Medicine 46:12, pages 1650-1657.
Crossref
Shelly C. Lu. (2009) Regulation of glutathione synthesis. Molecular Aspects of Medicine 30:1-2, pages 42-59.
Crossref
Hongqiao Zhang, Albert Shih, Alessandra Rinna & Henry Jay Forman. (2009) Resveratrol and 4-hydroxynonenal act in concert to increase glutamate cysteine ligase expression and glutathione in human bronchial epithelial cells. Archives of Biochemistry and Biophysics 481:1, pages 110-115.
Crossref
Rukhsana Sultana & D. Allan Butterfield. 2009. Neuroproteomics. Neuroproteomics 123 135 .
Henry Jay Forman, Jon M. Fukuto, Tom Miller, Hongqiao Zhang, Alessandra Rinna & Smadar Levy. (2008) The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal. Archives of Biochemistry and Biophysics 477:2, pages 183-195.
Crossref
Alessandra Rinna & Henry Jay Forman. (2008) SHP-1 Inhibition by 4-Hydroxynonenal Activates Jun N-Terminal Kinase and Glutamate Cysteine Ligase. American Journal of Respiratory Cell and Molecular Biology 39:1, pages 97-104.
Crossref
G. Poli, R.J. Schaur, W.G. Siems & G. Leonarduzzi. (2007) 4‐Hydroxynonenal: A membrane lipid oxidation product of medicinal interest. Medicinal Research Reviews 28:4, pages 569-631.
Crossref
Yumei Fu, Shizhong Zheng, Shelly C. Lu & Anping Chen. (2008) Epigallocatechin-3-gallate Inhibits Growth of Activated Hepatic Stellate Cells by Enhancing the Capacity of Glutathione Synthesis. Molecular Pharmacology 73:5, pages 1465-1473.
Crossref
Hongqiao Zhang & Henry Jay Forman. (2008) Acrolein Induces Heme Oxygenase-1 through PKC-δ and PI3K in Human Bronchial Epithelial Cells. American Journal of Respiratory Cell and Molecular Biology 38:4, pages 483-490.
Crossref
Javier Pereda, Javier Escobar, Juan Sandoval, José Luis Rodríguez, Luis Sabater, Federico V. Pallardó, Luis Torres, Luis Franco, José Viña, Gerardo López-Rodas & Juan Sastre. (2008) Glutamate cysteine ligase up-regulation fails in necrotizing pancreatitis. Free Radical Biology and Medicine 44:8, pages 1599-1609.
Crossref
A Negre-Salvayre, C Coatrieux, C Ingueneau & R Salvayre. (2008) Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors. British Journal of Pharmacology 153:1, pages 6-20.
Crossref
Lawrence M. Sayre, George Perry & Mark A. Smith. (2007) Oxidative Stress and Neurotoxicity. Chemical Research in Toxicology 21:1, pages 172-188.
Crossref
Laura E. Randle, Chris E.P. Goldring, Craig A. Benson, Peter N. Metcalfe, Neil R. Kitteringham, B. Kevin Park & Dominic P. Williams. (2008) Investigation of the effect of a panel of model hepatotoxins on the Nrf2-Keap1 defence response pathway in CD-1 mice. Toxicology 243:3, pages 249-260.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.