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Redox Report
Communications in Free Radical Research
Volume 14, 2009 - Issue 6
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Research articles

Overexpression of Prdx6 and resistance to peroxide-induced death in Hepa1-6 cells: Prdx suppression increases apoptosis

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Pages 275-284 | Published online: 19 Jul 2013

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Jun Xu, Qiang Su, Mingxia Gao, Qingsong Liang, Junfeng Li & Xu Chen. (2019) Differential Expression And Effects Of Peroxiredoxin-6 On Drug Resistance And Cancer Stem Cell-Like Properties In Non-Small Cell Lung Cancer. OncoTargets and Therapy 12, pages 10477-10486.
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Articles from other publishers (40)

Carla Peres de Paula, João Pedro Maia de Oliveira da Silva, Karen Simone Romanello, Victoria Simões Bernardo, Flaviene Felix Torres, Danilo Grünig Humberto da Silva & Anderson Ferreira da Cunha. (2023) Peroxiredoxins in erythrocytes: far beyond the antioxidant role. Journal of Molecular Medicine 101:11, pages 1335-1353.
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Yan Liu, Pu Wang, Weina Hu & Da Chen. (2023) New insights into the roles of peroxiredoxins in cancer. Biomedicine & Pharmacotherapy 164, pages 114896.
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Unbin Chae, Bokyung Kim, HanSeop Kim, Young-Ho Park, Seung Hwan Lee, Sun-Uk Kim & Dong-Seok Lee. (2021) Peroxiredoxin-6 regulates p38-mediated epithelial–mesenchymal transition in HCT116 colon cancer cells. Journal of Biological Research-Thessaloniki 28:1.
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Hui Yang, Gang Li & Guangping Qiu. (2021) Bioinformatics Analysis Using ATAC-seq and RNA-seq for the Identification of 15 Gene Signatures Associated With the Prediction of Prognosis in Hepatocellular Carcinoma. Frontiers in Oncology 11.
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Chen Chen, Lijie Gong, Xiaoqin Liu, Tianyu Zhu, Wuxi Zhou, Lingyi Kong & Jianguang Luo. (2021) Identification of peroxiredoxin 6 as a direct target of withangulatin A by quantitative chemical proteomics in non-small cell lung cancer. Redox Biology 46, pages 102130.
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Congcong Wang, Huanhuan Feng, Xiangle Zhang, Kangli Li, Fan Yang, Weijun Cao, Huisheng Liu, Lili Gao, Zhaoning Xue, Xiangtao Liu, Zixiang Zhu & Haixue Zheng. (2021) Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function. Virologica Sinica 36:5, pages 948-957.
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Robson Seriani, Carla Peres de Paula, Anderson Ferreira da Cunha, Marcos Antonio de Oliveira, Paloma Gava Krempel, Daniela Perroni Frias, Elnara Marcia Negri, Thais Mauad & Mariangela Macchione. (2021) Expression patterns of peroxiredoxin genes in bronchial epithelial cells exposed to diesel exhaust particles. Experimental and Molecular Pathology 120, pages 104641.
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Shu-yan Liu, Dai Yuan, Rui-Jie Sun, Jing-jing Zhu & Ning-ning Shan. (2020) Significant reductions in apoptosis-related proteins (HSPA6, HSPA8, ITGB3, YWHAH, and PRDX6) are involved in immune thrombocytopenia. Journal of Thrombosis and Thrombolysis 51:4, pages 905-914.
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Yinhuan Zhang, Xiaowei Yang, Zhixin Jia, Jie Liu, Xiaoning Yan, Yihang Dai & Hongbin Xiao. (2020) Proteomics Unravels Emodin Causes Liver Oxidative Damage Elicited by Mitochondrial Dysfunction. Frontiers in Pharmacology 11.
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M. G. Sharapov & V. I. Novoselov. (2019) Catalytic and Signaling Role of Peroxiredoxins in Carcinogenesis. Biochemistry (Moscow) 84:2, pages 79-100.
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John Skoko, Shireen Attaran & Carola Neumann. (2019) Signals Getting Crossed in the Entanglement of Redox and Phosphorylation Pathways: Phosphorylation of Peroxiredoxin Proteins Sparks Cell Signaling. Antioxidants 8:2, pages 29.
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Mars G. Sharapov, Vladimir I. Novoselov & Sergey V. Gudkov. (2019) Radioprotective Role of Peroxiredoxin 6. Antioxidants 8:1, pages 15.
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José Arevalo & José Vázquez-Medina. (2018) The Role of Peroxiredoxin 6 in Cell Signaling. Antioxidants 7:12, pages 172.
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Mark B. HamptonKate A. VickJohn J. SkokoCarola A. Neumann. (2018) Peroxiredoxin Involvement in the Initiation and Progression of Human Cancer. Antioxidants & Redox Signaling 28:7, pages 591-608.
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Arun K. B., Aravind Madhavan, Reshmitha T. R.Sithara ThomasP. Nisha. (2018) Musa paradisiaca inflorescence induces human colon cancer cell death by modulating cascades of transcriptional events . Food & Function 9:1, pages 511-524.
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Silvia Yumnam, Venu Venkatarame Gowda Saralamma, Suchismita Raha, Ho Jeong Lee, Won Sup Lee, Eun Hee Kim, Sang Joon Lee, Jeong Doo Heo & Gon Sup Kim. (2017) Proteomic profiling of human HepG2 cells treated with hesperidin using antibody array. Molecular Medicine Reports 16:4, pages 5386-5392.
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Aron B. Fisher. (2017) Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling. Archives of Biochemistry and Biophysics 617, pages 68-83.
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Xiao Xu, Di Lu, Runzhou Zhuang, Xuyong Wei, Haiyang Xie, Chao Wang, Yangbo Zhu, Jianguo Wang, Cheng Zhong, Xuanyu Zhang, Qiang Wei, Zenglei He, Lin Zhou & Shusen Zheng. (2016) The phospholipase A2 activity of peroxiredoxin 6 promotes cancer cell death induced by tumor necrosis factor alpha in hepatocellular carcinoma. Molecular Carcinogenesis 55:9, pages 1299-1308.
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Mi Hee Park, MiRan Jo, Yu Ri Kim, Chong-Kil Lee & Jin Tae Hong. (2016) Roles of peroxiredoxins in cancer, neurodegenerative diseases and inflammatory diseases. Pharmacology & Therapeutics 163, pages 1-23.
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Sh. Anwar, T. Yanai & H. Sakai. (2016) Overexpression of Peroxiredoxin 6 Protects Neoplastic Cells against Apoptosis in Canine Haemangiosarcoma. Journal of Comparative Pathology 155:1, pages 29-39.
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Ibrahim O. Alanazi & Esmaeil Ebrahimie. (2016) Computational Systems Biology Approach Predicts Regulators and Targets of microRNAs and Their Genomic Hotspots in Apoptosis Process. Molecular Biotechnology 58:7, pages 460-479.
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Angela María Gonella-Diaza, Sónia Cristina da Silva Andrade, Mariana Sponchiado, Guilherme Pugliesi, Fernando Silveira Mesquita, Veerle Van Hoeck, Ricardo de Francisco Strefezzi, Gustavo R. Gasparin, Luiz L. Coutinho & Mario Binelli. (2015) Size of the Ovulatory Follicle Dictates Spatial Differences in the Oviductal Transcriptome in Cattle. PLOS ONE 10:12, pages e0145321.
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Hye Lim Lee, Mi Hee Park, Dong Ju Son, Ho Sueb Song, Jung Hyun Kim, Seong Cheol Ko, Min Jong Song, Won Hyoung Lee, Joo Hee Yoon, Young Wan Ham, Sang Bae Han & Jin Tae Hong. (2015) Anti-cancer effect of snake venom toxin through down regulation of AP-1 mediated PRDX6 expression. Oncotarget 6:26, pages 22139-22151.
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Ibrahim Alanazi, Peter Hoffmann & David L. Adelson. (2015) MicroRNAs Are Part of the Regulatory Network that Controls EGF Induced Apoptosis, Including Elements of the JAK/STAT Pathway, in A431 Cells. PLOS ONE 10:3, pages e0120337.
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Hyung-Mun Yun, Kyung-Ran Park, Mi Hee Park, Dae Hwan Kim, Mi Ran Jo, Ji Young Kim, Eun-Cheol Kim, Do Young Yoon, Sang Bae Han & Jin Tae Hong. (2015) PRDX6 promotes tumor development via the JAK2/STAT3 pathway in a urethane-induced lung tumor model. Free Radical Biology and Medicine 80, pages 136-144.
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Xiao Zhang, Lan-lan Shi, Xia Gao, Di Jiang, Zhan-qiong Zhong, Xi Zeng, Ying Rao, Xi Hu, Tian-zhi Li, Xiu-juan Li, Lei Li, Jian-min Chen, Qingjie Xia & Ting-hua Wang. (2015) Lentivirus-mediated Inhibition of Tumour Necrosis Factor-α improves motor function associated with PRDX6 in spinal cord contusion rats. Scientific Reports 5:1.
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Xiaofei Li, Qi Wang, Yanni Gao, Xiaole Qi, Yongqiang Wang, Honglei Gao, Yulong Gao & Xiaomei Wang. (2015) Quantitative iTRAQ LC-MS/MS Proteomics Reveals the Proteome Profiles of DF-1 Cells after Infection with Subgroup J Avian Leukosis Virus. BioMed Research International 2015, pages 1-10.
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Ping Chen, Lixiang Wang, Yong Wang, Shuiming Li, Liming Shen, Qiong Liu & Jiazuan Ni. (2014) Phosphoproteomic Profiling of Selenate-Treated Alzheimer's Disease Model Cells. PLoS ONE 9:12, pages e113307.
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Hyung-Mun Yun, Kyung-Ran Park, Hee Peum Lee, Dong Hun Lee, Miran Jo, Dea Hwan Shin, Do-Young Yoon, Sang Bae Han & Jin Tae Hong. (2014) PRDX6 promotes lung tumor progression via its GPx and iPLA2 activities. Free Radical Biology and Medicine 69, pages 367-376.
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Wen-Ting Chen, Yi-Le Wu, Ting Chen, Chao-Sheng Cheng, Hong-Lin Chan, Hsiu-Chuan Chou, Yi-Wen Chen & Hsien-Sheng Yin. (2014) Proteomics Analysis of the DF-1 Chicken Fibroblasts Infected with Avian Reovirus Strain S1133. PLoS ONE 9:3, pages e92154.
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Miran Jo, Hyung-Mun Yun, Kyung-Ran Park, Mi Hee Park, Dong Hun Lee, Seung Hee Cho, Hwan-Soo Yoo, Yong-Moon Lee, Heon Sang Jeong, Youngsoo Kim, Jae Kyung Jung, Bang Yeon Hwang, Mi Kyeong Lee, Nam Doo Kim, Sang Bae Han & Jin Tae Hong. (2014) Anti-Cancer Effect of Thiacremonone through Down Regulation of Peroxiredoxin 6. PLoS ONE 9:3, pages e91508.
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Lucia Laura PolicastroIrene Laura IbañezCintia NotcovichHebe Alicia DuranOsvaldo Luis Podhajcer. (2013) The Tumor Microenvironment: Characterization, Redox Considerations, and Novel Approaches for Reactive Oxygen Species-Targeted Gene Therapy. Antioxidants & Redox Signaling 19:8, pages 854-895.
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Andréia M. Leopoldino, Cristiane H. Squarize, Cristiana B. Garcia, Luciana O. Almeida, Cezar R. Pestana, Lays M. Sobral, Sérgio A. Uyemura, Eloiza H. Tajara, J. Silvio Gutkind & Carlos Curti. (2012) SET protein accumulates in HNSCC and contributes to cell survival: Antioxidant defense, Akt phosphorylation and AVOs acidification. Oral Oncology 48:11, pages 1106-1113.
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Zhongjun Fan, Xuming Hu, Yongpan Zhang, Chuan Yu, Kun Qian & Aijian Qin. (2012) Proteomics of DF-1 cells infected with avian leukosis virus subgroup J. Virus Research 167:2, pages 314-321.
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Yang Lu, Xiaoluan Liu, Suozhu Shi, Huabin Su, Xueyuan Bai, Guangyan Cai, Fuquan Yang, Zhensheng Xie, Yunping Zhu, Yanqiong Zhang, Shujia Zhang, Xiaofan Li, Shan Wang, Di Wu, Li Zhang, Jie Wu, Yuansheng Xie & Xiangmei Chen. (2012) Bioinformatics Analysis of Proteomic Profiles During the Process of Anti-Thy1 Nephritis. Molecular & Cellular Proteomics 11:4, pages M111.008755.
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Andréia M. Leopoldino, Cristiane H. Squarize, Cristiana B. Garcia, Luciana O. Almeida, Cezar R. Pestana, Ana C. M. Polizello, Sérgio A. Uyemura, Eloiza H. Tajara, J. Silvio Gutkind & Carlos Curti. (2011) Accumulation of the SET protein in HEK293T cells and mild oxidative stress: cell survival or death signaling. Molecular and Cellular Biochemistry 363:1-2, pages 65-74.
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Hong Lu, Xin-yue Zhang, Yan-quan Zhou, Xin Wen & Li-ying Zhu. (2011) Proteomic alterations in mouse kidney induced by andrographolide sodium bisulfite. Acta Pharmacologica Sinica 32:7, pages 888-894.
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Qi Zhou, Fang Wang, Yi Zhang, Fu Yang, Yue Wang & Shuhan Sun. (2011) Down-regulation of Prdx6 contributes to DNA vaccine induced vitiligo in mice. Mol. BioSyst. 7:3, pages 809-816.
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Krishnananda Prabhu, Gummadi Maheshwar Reddy & Anjali Rao. (2010) Can antioxidants predispose to cancer recurrence?. Asian Pacific Journal of Tropical Medicine 3:6, pages 494-495.
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