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Special Interest: EAS, PDCI, PDT and Hearing Preservation

Inhibition of the JNK Signal Cascade Conserves Hearing Against Electrode Insertion Trauma-Induced Loss

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Pages 104-109 | Published online: 18 Jul 2013

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Joshua A. Tillinger, Chhavi Gupta, Kadri Ila, Jamal Ahmed, Jeenu Mittal, Thomas R. Van De Water & Adrien A. Eshraghi. (2018) l-N-acetylcysteine protects outer hair cells against TNFα initiated ototoxicity in vitro. Acta Oto-Laryngologica 138:8, pages 676-684.
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Adrien A. Eshraghi, Jonathan Roell, Noah Shaikh, Fred F. Telischi, Blake Bauer, Mateo Guardiola, Esperanza Bas, Thomas Van De Water, Ileana Rivera & Jeenu Mittal. (2016) A novel combination of drug therapy to protect residual hearing post cochlear implant surgery. Acta Oto-Laryngologica 136:4, pages 420-424.
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Friedrich Ihler, Sabrina Pelz, Melanie Coors, Christoph Matthias & Martin Canis. (2014) Application of a TNF-alpha-inhibitor into the scala tympany after cochlear electrode insertion trauma in guinea pigs: Preliminary audiologic results. International Journal of Audiology 53:11, pages 810-816.
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Articles from other publishers (10)

Rachele Sangaletti, Ilmar Tamames, Stephanie Lynn Yahn, James Seungyeon Choi, Jae K. Lee, Curtis King & Suhrud M. Rajguru. (2022) Mild therapeutic hypothermia protects against inflammatory and proapoptotic processes in the rat model of cochlear implant trauma. Hearing Research, pages 108680.
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Muhammad T. Rahman, Divya A. Chari, Gail Ishiyama, Ivan Lopez, Alicia M. Quesnel, Akira Ishiyama, Joseph B. Nadol & Marlan R. Hansen. (2022) Cochlear implants: Causes, effects and mitigation strategies for the foreign body response and inflammation. Hearing Research 422, pages 108536.
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Cristina Maria Blebea, Laszlo Peter Ujvary, Violeta Necula, Maximilian George Dindelegan, Maria Perde-Schrepler, Mirela Cristina Stamate, Marcel Cosgarea & Alma Aurelia Maniu. (2022) Current Concepts and Future Trends in Increasing the Benefits of Cochlear Implantation: A Narrative Review. Medicina 58:6, pages 747.
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Jose M. Bermúdez-Muñoz, Adelaida M. Celaya, Ángela García-Mato, Daniel Muñoz-Espín, Lourdes Rodríguez-de la Rosa, Manuel Serrano & Isabel Varela-Nieto. (2021) Dual-Specificity Phosphatase 1 (DUSP1) Has a Central Role in Redox Homeostasis and Inflammation in the Mouse Cochlea. Antioxidants 10:9, pages 1351.
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Adrien A. Eshraghi, Amit Wolfovitz, Rasim Yilmazer, Carolyn Garnham, Ayca Baskadem Yilmazer, Esperanza Bas, Peter Ashman, Jonathan Roell, Jorge Bohorquez, Rahul Mittal, Roland Hessler, Daniel Sieber & Jeenu Mittal. (2019) Otoprotection to Implanted Cochlea Exposed to Noise Trauma With Dexamethasone Eluting Electrode. Frontiers in Cellular Neuroscience 13.
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Adrien A. Eshraghi, Mayank Aranke, Richard Salvi, Dalian Ding, John K.M. ColemanJr.Jr., Emre Ocak, Rahul Mittal & Thomas Meyer. (2018) Preclinical and clinical otoprotective applications of cell-penetrating peptide D-JNKI-1 (AM-111). Hearing Research 368, pages 86-91.
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Ying XingJie MingTao LiuNana ZhangDingjun Zha & Ying Lin. (2018) Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment. Yonsei Medical Journal 59:9, pages 1131.
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Christine T. Dinh, Stefania Goncalves, Esperanza Bas, Thomas R. Van De Water & Azel Zine. (2015) Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma. Frontiers in Cellular Neuroscience 9.
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Leonard P. Rybak & Michael J. Brenner. 2015. Free Radicals in ENT Pathology. Free Radicals in ENT Pathology 195 216 .
Huan Jia, Jing Wang, Florence François, Alain Uziel, Jean-Luc Puel & Frédéric Venail. (2013) Molecular and Cellular Mechanisms of Loss of Residual Hearing after Cochlear Implantation. Annals of Otology, Rhinology & Laryngology 122:1, pages 33-39.
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