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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 15, 2012 - Issue 5
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Research articles

Alpha-mangostin induces changes in glutathione levels associated with glutathione peroxidase activity in rat brain synaptosomes

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Pages 13-19 | Published online: 19 Jul 2013

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Khairy A. Ibrahim, Mohammed Eleyan, Soad A. Khwanes, Rania A. Mohamed & Basim M. Ayesh. (2022) Alpha-mangostin attenuates the apoptotic pathway of abamectin in the fetal rats’ brain by targeting pro-oxidant stimulus, catecholaminergic neurotransmitters, and transcriptional regulation of reelin and nestin. Drug and Chemical Toxicology 45:6, pages 2496-2508.
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Rubén Estrada-Valencia, María Ester Hurtado-Díaz, Edgar Rangel-López, Socorro Retana-Márquez, Isaac Túnez, Alexey Tinkov, Cimen Karasu, Beatriz Ferrer, José Pedraza-Chaverri, Michael Aschner & Abel Santamaría. (2022) Alpha-Mangostin Alleviates the Short-term 6-Hydroxydopamine-Induced Neurotoxicity and Oxidative Damage in Rat Cortical Slices and in Caenorhabditis elegans. Neurotoxicity Research 40:2, pages 573-584.
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Charinya So-In & Nuchsupha Sunthamala. (2022) Treatment efficacy of Thunbergia laurifolia, Curcuma longa, Garcinia mangostana, and Andrographis paniculata extracts in Staphylococcus aureus-induced rabbit dermatitis model. Veterinary World, pages 188-197.
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Alberto Rojas-Ochoa, Emilio J. Córdova, Adela Carrillo-García, Marcela Lizano, José Pedraza-Chaverri, Nelly Patiño, Alfredo Cruz-Gregorio & Norma Osnaya. (2021) The Polyphenols α-Mangostin and Nordihydroguaiaretic Acid Induce Oxidative Stress, Cell Cycle Arrest, and Apoptosis in a Cellular Model of Medulloblastoma. Molecules 26:23, pages 7230.
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Lim Chiew VienSasikala ChinnappanMogana R. (2021) Antioxidant activity of Garcinia mangostana L and alpha mangostin: A Review. Research Journal of Pharmacy and Technology, pages 4466-4470.
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Aihong Yang, Chang Liu, Jiarui Wu, Xiaodi Kou & Rui Shen. (2021) A review on α-mangostin as a potential multi-target-directed ligand for Alzheimer's disease. European Journal of Pharmacology 897, pages 173950.
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Mahboobeh Ghasemzadeh Rahbardar, Bibi Marjan Razavi & Hossein Hosseinzadeh. (2020) Investigating the ameliorative effect of alpha‐mangostin on development and existing pain in a rat model of neuropathic pain. Phytotherapy Research 34:12, pages 3211-3225.
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Jana Lotter, Marisa Möller, Olivia Dean, Michael Berk & Brian H. Harvey. (2020) Studies on Haloperidol and Adjunctive α-Mangostin or Raw Garcinia mangostana Linn Pericarp on Bio-Behavioral Markers in an Immune-Inflammatory Model of Schizophrenia in Male Rats. Frontiers in Psychiatry 11.
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Abhijeet Parkhe, Pathik Parekh, Lakshmi Vineela Nalla, Nishant Sharma, Monika Sharma, Anagha Gadepalli, Abhijeet Kate & Amit Khairnar. (2020) Protective effect of alpha mangostin on rotenone induced toxicity in rat model of Parkinson’s disease. Neuroscience Letters 716, pages 134652.
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Abhijit Dey, Banadipa Nanda, Samapika Nandy, Anuradha Mukherjee & Devendra Kumar Pandey. 2020. Bioactive Natural Products. Bioactive Natural Products 27 79 .
Samaneh Soleymani, Mohammad Hosein Farzaei, Arman Zargaran, Somayeh Niknam & Roja Rahimi. (2019) Promising plant-derived secondary metabolites for treatment of acne vulgaris: a mechanistic review. Archives of Dermatological Research 312:1, pages 5-23.
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Melanie M. Ashton, Olivia M. Dean, Adam J. Walker, Chiara C. Bortolasci, Chee H. Ng, Malcolm Hopwood, Brian H. Harvey, Marisa Möller, John J. McGrath, Wolfgang Marx, Alyna Turner, Seetal Dodd, James G. Scott, Jon-Paul Khoo, Ken Walder, Jerome Sarris & Michael Berk. (2019) The Therapeutic Potential of Mangosteen Pericarp as an Adjunctive Therapy for Bipolar Disorder and Schizophrenia. Frontiers in Psychiatry 10.
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Tianhua Fu, Haijun Li, Yan Zhao, Enbo Cai, Hongyan Zhu, Pingya Li & Jinping Liu. (2018) Hepatoprotective effect of α-mangostin against lipopolysaccharide/d-galactosamine-induced acute liver failure in mice. Biomedicine & Pharmacotherapy 106, pages 896-901.
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Shaista Chaudhary & Suhel Parvez. (2018) Valproic Acid Induced Neurotoxicological Manifestations and its Mitigation by Melatonin in Rat Brain Synaptosomes. Archives of Medical Research 49:7, pages 441-450.
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Shaista Chaudhary & Suhel Parvez. (2017) Phytanic acid induced neurological alterations in rat brain synaptosomes and its attenuation by melatonin. Biomedicine & Pharmacotherapy 95, pages 37-46.
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Abhijit Dey. 2017. Neuroprotective Natural Products. Neuroprotective Natural Products 185 246 .
Ming-Hui WANG, Kuo-Jun ZHANG, Qin-Lan GU, Xiao-Ling BI & Jin-Xin WANG. (2017) Pharmacology of mangostins and their derivatives: A comprehensive review. Chinese Journal of Natural Medicines 15:2, pages 81-93.
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Shin-Yu Tsai, Pei-Chin Chung, Eddy E. Owaga, I-Jong Tsai, Pei-Yuan Wang, Jeng-I Tsai, Tien-Shun Yeh & Rong-Hong Hsieh. (2016) Alpha-mangostin from mangosteen (Garcinia mangostana Linn.) pericarp extract reduces high fat-diet induced hepatic steatosis in rats by regulating mitochondria function and apoptosis. Nutrition & Metabolism 13:1.
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Miryam Nava Catorce, Gonzalo Acero, José Pedraza-Chaverri, Gladis Fragoso, Tzipe Govezensky & Goar Gevorkian. (2016) Alpha-mangostin attenuates brain inflammation induced by peripheral lipopolysaccharide administration in C57BL/6J mice. Journal of Neuroimmunology 297, pages 20-27.
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Jazmin M. Pérez-Rojas, Raquel González-Macías, Jaime González-Cortes, Rafael Jurado, José Pedraza-Chaverri & Patricia García-López. (2016) Synergic Effect of α -Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model . Oxidative Medicine and Cellular Longevity 2016, pages 1-13.
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Prachya Janhom & Permphan Dharmasaroja. (2015) Neuroprotective Effects of Alpha-Mangostin on MPP + -Induced Apoptotic Cell Death in Neuroblastoma SH-SY5Y Cells . Journal of Toxicology 2015, pages 1-11.
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Chengchong Li, Zhi Pan, Tianjiao Xu, Chun Zhang, Qi Wu & Yingcai Niu. (2014) Puerarin induces the upregulation of glutathione levels and nuclear translocation of Nrf2 through PI3K/Akt/GSK-3β signaling events in PC12 cells exposed to lead. Neurotoxicology and Teratology 46, pages 1-9.
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Hei-Jen Huang, Wei-Lin Chen, Rong-Hong Hsieh & Hsiu Mei Hsieh-Li. (2014) Multifunctional Effects of Mangosteen Pericarp on Cognition in C57BL/6J and Triple Transgenic Alzheimer’s Mice. Evidence-Based Complementary and Alternative Medicine 2014, pages 1-18.
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Tonali Blanco-Ayala, Rafael Lugo-Huitrón, Elizabeth M Serrano-López, Ricardo Reyes-Chilpa, Edgar Rangel-López, Benjamín Pineda, Omar Noel Medina-Campos, Laura Sánchez-Chapul, Enrique Pinzón, Trejo-Solis Cristina, Daniela Silva-Adaya, José Pedraza-Chaverrí, Camilo Ríos, Verónica Pérez de la Cruz & Mónica Torres-Ramos. (2013) Antioxidant properties of xanthones from Calophyllum brasiliense: prevention of oxidative damage induced by FeSO4. BMC Complementary and Alternative Medicine 13:1.
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