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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 16, 2013 - Issue 4
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Original research papers

Zinc deficiency regulates hippocampal gene expression and impairs neuronal differentiation

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Pages 174-182 | Published online: 19 Jul 2013

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Winyoo Chowanadisai, David M Graham, Carl L Keen, Robert B Rucker & Mark A Messerli. (2013) A zinc transporter gene required for development of the nervous system. Communicative & Integrative Biology 6:6.
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Articles from other publishers (36)

Madeline M. Ross, Diego R. Hernandez-Espinosa & Elias Aizenman. (2023) Neurodevelopmental Consequences of Dietary Zinc Deficiency: A Status Report. Biological Trace Element Research 201:12, pages 5616-5639.
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Ceyhan Hacioglu, Fatih Kar & Meryem Cansu Sahin. (2023) Neurochemical Research of LOXBlock-1 and ZnSO4 against Neurodegenerative Damage Induced by Amyloid Beta(1-42). Biological Trace Element Research.
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Xiuzhen Liu, Ana M. Adamo & Patricia I. Oteiza. (2023) Marginal Zinc Deficiency during Gestation and Lactation in Rats Affects Oligodendrogenesis, Motor Performance, and Behavior in the Offspring. The Journal of Nutrition 153:10, pages 2778-2796.
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Bangqi Wang, Tianshu Fang & Hongping Chen. (2023) Zinc and Central Nervous System Disorders. Nutrients 15:9, pages 2140.
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Amr Ahmed, Amr Ghit, Asmaa Houjak & Mahmoud Elkazzaz. 2023. COVID-19 Pandemic, Mental Health and Neuroscience - New Scenarios for Understanding and Treatment. COVID-19 Pandemic, Mental Health and Neuroscience - New Scenarios for Understanding and Treatment.
Hiroyuki Ikushima, Jun Suzuki, Tomotaka Hemmi, Ryoukichi Ikeda, Yuta Kobayashi, Nobuo Ohta & Yukio Katori. (2023) Effects of zinc deficiency on the regeneration of olfactory epithelium in mice. Chemical Senses 48.
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Neda Valian. 2023. Trace Elements in Brain Health and Diseases. Trace Elements in Brain Health and Diseases 71 93 .
Xiaoqiang Mo, Mengxue Liu, Jihong Gong, Ying Mei, Huidan Chen, Huajun Mo, Xiaofei Yang & Jun Li. (2022) PTPRM Is Critical for Synapse Formation Regulated by Zinc Ion. Frontiers in Molecular Neuroscience 15.
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Francisco Jose Grisanti Canozo, Zhen Zuo, James F. Martin & Md. Abul Hassan Samee. (2022) Cell-type modeling in spatial transcriptomics data elucidates spatially variable colocalization and communication between cell-types in mouse brain. Cell Systems 13:1, pages 58-70.e5.
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Luc P. Brion, Roy Heyne & Cheryl S. Lair. (2020) Role of zinc in neonatal growth and brain growth: review and scoping review. Pediatric Research 89:7, pages 1627-1640.
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Masanobu Suzuki, Takayoshi Suzuki, Masashi Watanabe, Shigetsugu Hatakeyama, Shogo Kimura, Akira Nakazono, Aya Honma, Yuji Nakamaru, Sarah Vreugde & Akihiro Homma. (2021) Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases. Allergology International 70:2, pages 190-200.
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Vitor Alves Sá da Silva, Ana Layla Carvalho de Lima, Lucia Codognoto, Tiago Luiz Ferreira, Mauro Coelho dos Santos, Giselle Cerchiaro & Eliana Maira Agostini Valle. (2021) Electrochemical and spectroscopy studies of the interaction between the Zn2+ and the diethylditiocarbamate ligand (Et2DTC−). Transition Metal Chemistry 46:4, pages 291-297.
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Basma Ekram, Bothaina M Abd El-Hady, Abeer M El-Kady, Mohamed T Fouad, Zeinab I Sadek, Sherif M Amr, Hala Gabr, Ahmed I Waly & Osiris W Guirguis. (2021) Enhanced mesenchymal stem cells growth on antibacterial microgrooved electrospun zinc chloride/polycaprolactone conduits for peripheral nerve regeneration. Journal of Bioactive and Compatible Polymers 36:2, pages 152-168.
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Vijay Kumar, Ashok Kumar, Kritanjali Singh, Kapil Avasthi & Jong-Joo Kim. (2021) Neurobiology of zinc and its role in neurogenesis. European Journal of Nutrition 60:1, pages 55-64.
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Seunghyuk Choi, Dae Ki Hong, Bo Young Choi & Sang Won Suh. (2020) Zinc in the Brain: Friend or Foe?. International Journal of Molecular Sciences 21:23, pages 8941.
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Chien-Yuan Pan, Fang-Yu Lin, Lung-Sen Kao, Chien-Chang Huang & Pei-Shan Liu. (2020) Zinc oxide nanoparticles modulate the gene expression of ZnT1 and ZIP8 to manipulate zinc homeostasis and stress-induced cytotoxicity in human neuroblastoma SH-SY5Y cells. PLOS ONE 15:9, pages e0232729.
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Andreas M. Grabrucker. 2020. Biometals in Autism Spectrum Disorders. Biometals in Autism Spectrum Disorders 43 60 .
Christopher M. Elitt, Christoph J. Fahrni & Paul A. Rosenberg. (2019) Zinc homeostasis and zinc signaling in white matter development and injury. Neuroscience Letters 707, pages 134247.
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Ana M. Adamo, Xiuzhen Liu, Patricia Mathieu, Johnathan R. Nuttall, Suangsuda Supasai & Patricia I. Oteiza. (2019) Early Developmental Marginal Zinc Deficiency Affects Neurogenesis Decreasing Neuronal Number and Altering Neuronal Specification in the Adult Rat Brain. Frontiers in Cellular Neuroscience 13.
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Huili Li, Jing Zhang & Lee Niswander. (2018) Zinc deficiency causes neural tube defects through attenuation of p53 ubiquitylation. Development 145:24.
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Mi-Young Moon, Hyun Jung Kim, Bo Young Choi, Min Sohn, Tae Nyoung Chung & Sang Won Suh. (2018) Zinc Promotes Adipose-Derived Mesenchymal Stem Cell Proliferation and Differentiation towards a Neuronal Fate. Stem Cells International 2018, pages 1-9.
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Sung Min Nam, Jong Whi Kim, Hyun Jung Kwon, Dae Young Yoo, Hyo Young Jung, Dae Won Kim, In Koo Hwang, Je Kyung Seong & Yeo Sung Yoon. (2017) Differential Effects of Low- and High-dose Zinc Supplementation on Synaptic Plasticity and Neurogenesis in the Hippocampus of Control and High-fat Diet-fed Mice. Neurochemical Research 42:11, pages 3149-3159.
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Neha Singla & D. K. Dhawan. (2016) Zinc Improves Cognitive and Neuronal Dysfunction During Aluminium-Induced Neurodegeneration. Molecular Neurobiology 54:1, pages 406-422.
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S. Kim, D. M. Barry, X.-Y. Liu, S. Yin, A. Munanairi, Q.-T. Meng, W. Cheng, P. Mo, L. Wan, S.-B. Liu, K. Ratnayake, Z.-Q. Zhao, N. Gautam, J. Zheng, W. K. A. Karunarathne & Z.-F. Chen. (2016) Facilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populations. Science Signaling 9:437, pages ra71-ra71.
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Elise C. Cope, Deborah R. Morris, Shannon D. Gower-Winter, Naomi C. Brownstein & Cathy W. Levenson. (2016) Effect of zinc supplementation on neuronal precursor proliferation in the rat hippocampus after traumatic brain injury. Experimental Neurology 279, pages 96-103.
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Eduardo E. Benarroch. (2016) Dorsal horn circuitry. Neurology 86:11, pages 1060-1069.
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Stefanie Pfaender, Karl Föhr, Anne-Kathrin Lutz, Stefan Putz, Kevin Achberger, Leonhard Linta, Stefan Liebau, Tobias M. Boeckers & Andreas M. Grabrucker. (2016) Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells. Neural Plasticity 2016, pages 1-15.
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Jingling Han, Jianya Zhao, Junkang Jiang, Xia Ma, Xinhang Liu, Cheng Wang, Shengyang Jiang & Chunhua Wan. (2015) Zinc deficiency impairs the renewal of hippocampal neural stem cells in adult rats: involvement of FoxO3a activation and downstream p27 kip1 expression . Journal of Neurochemistry 134:5, pages 879-891.
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Jianya Zhao, Jingling Han, Junkang Jiang, Shangshi Shi, Xia Ma, Xinhang Liu, Cheng Wang, Xiaoke Nie, Yunhua He, Shengyang Jiang & Chunhua Wan. (2015) The downregulation of Wnt/β-catenin signaling pathway is associated with zinc deficiency-induced proliferative deficit of C17.2 neural stem cells. Brain Research 1615, pages 61-70.
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Gabriel Nowak. (2015) Zinc, future mono/adjunctive therapy for depression: Mechanisms of antidepressant action. Pharmacological Reports 67:3, pages 659-662.
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Katarzyna Młyniec, Magdalena Gaweł, Tadeusz Librowski, Witold Reczyński, Beata Bystrowska & Birgitte Holst. (2015) Investigation of the GPR39 zinc receptor following inhibition of monoaminergic neurotransmission and potentialization of glutamatergic neurotransmission. Brain Research Bulletin 115, pages 23-29.
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Neha Singla & D. K. Dhawan. (2014) Zinc down regulates Apaf-1-dependent Bax/Bcl-2 mediated caspases activation during aluminium induced neurotoxicity. BioMetals 28:1, pages 61-73.
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Hans Konrad BiesalskiHans Konrad Biesalski. 2015. Mikronährstoffe als Motor der Evolution. Mikronährstoffe als Motor der Evolution 189 219 .
Deborah R. Morris & Cathy W. Levenson. (2013) Zinc regulation of transcriptional activity during retinoic acid-induced neuronal differentiation. The Journal of Nutritional Biochemistry 24:11, pages 1940-1944.
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S. K. Mishra & M. A. Hoon. (2013) The Cells and Circuitry for Itch Responses in Mice. Science 340:6135, pages 968-971.
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