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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 17, 2014 - Issue 2
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Review

Acrylamide neurotoxicity

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Keep up to date with the latest research on this topic with citation updates for this article.

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Linlin Deng, Mengyao Zhao, Yanan Cui, Quanming Xia, Lihua Jiang, Hao Yin & Liming Zhao. (2022) Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells. Drug and Chemical Toxicology 45:6, pages 2601-2612.
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Mónica Quesada-Valverde, Graciela Artavia, Fabio Granados-Chinchilla & Carolina Cortés-Herrera. (2022) Acrylamide in foods: from regulation and registered levels to chromatographic analysis, nutritional relevance, exposure, mitigation approaches, and health effects. Toxin Reviews 41:4, pages 1343-1373.
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Leila Peivasteh-Roudsari, Marziyeh Karami, Raziyeh Barzegar-Bafrouei, Samane Samiee, Hadis Karami, Behrouz Tajdar-Oranj, Vahideh Mahdavi, Adel Mirza Alizadeh, Parisa Sadighara, Gea Oliveri Conti & Amin Mousavi Khaneghah. (2022) Toxicity, metabolism, and mitigation strategies of acrylamide: a comprehensive review. International Journal of Environmental Health Research 0:0, pages 1-29.
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Nan Bo, Hong Yilin, Yan Haiyang & Yuan Yuan. (2020) Acrylamide induced the activation of NLRP3 inflammasome via ROS-MAPKs pathways in Kupffer cells. Food and Agricultural Immunology 31:1, pages 45-62.
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J Wang, MY Zhang, SQ Xu, J Cheng, ZJ Yu & XM Hu. (2018) Down-regulation of telomerase reverse transcriptase-related anti-apoptotic function in a rat model of acrylamide induced neurobehavioral deficits. Biotechnic & Histochemistry 93:7, pages 512-518.
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Articles from other publishers (117)

Chloé Marques, Pauline Frenoy, Alexis Elbaz, Nasser Laouali, Sanam Shah, Gianluca Severi & Francesca Romana Mancini. (2024) Association between dietary intake of acrylamide and increased risk of mortality in women: Evidence from the E3N prospective cohort. Science of The Total Environment 906, pages 167514.
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Shunyu Xiang, Chloé Guilbaud-Chéreau, Paul Hoschtettler, Loïc Stefan, Alberto Bianco & Cécilia Ménard-Moyon. (2024) Preparation and optimization of agarose or polyacrylamide/amino acid-based double network hydrogels for photocontrolled drug release. International Journal of Biological Macromolecules 255, pages 127919.
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Luna Bridgeman, Cristina Juan, Ana Juan-García & Houda Berrada. (2023) Individual and combined effect of acrylamide, fumitremorgin C and penitrem A on human neuroblastoma SH-SY5Y cells. Food and Chemical Toxicology 182, pages 114114.
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Chuanqi Xie, Changyan Wang, Mengyao Zhao & Liming Zhao. (2023) Prediction of acrylamide content in potato chips using near-infrared spectroscopy. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 301, pages 122982.
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Hsiang-Han Su, Chih-Mei Cheng, Yung-Ning Yang, Yu-Wei Chang, Chia-Yang Li, Shin-Ting Wu, Chia-Chi Lin, Hsin-En Wu & Jau-Ling Suen. (2023) Acrylamide, an air pollutant, enhances allergen-induced eosinophilic lung inflammation via group 2 innate lymphoid cells. Mucosal Immunology.
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Liwen Zhang, Fanglue Wang, Dongchen Zhang, Jingyao Xu, Xuefeng Wu & Shengsong Deng. (2023) Systematic exploration of the interactions between anionic polyacrylamide and manganese peroxidase based on docking and molecular dynamics simulations. Catalysis Communications 183, pages 106758.
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Divya Gupta, Shubham Singh, Richa Soni, Shamli S. Gupte, Arti Rathour, Sadhana Shrivastava & Sangeeta Shukla. (2023) Possible metabolic effect of acrylamide on biological system. Food Safety and Health 1:2, pages 126-138.
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Zhengjiang Wang, Kaili Li, Xuwei Gui & Zhenlun Li. (2023) Acidovorax PSJ13, a novel, efficient polyacrylamide-degrading bacterium by cleaving the main carbon chain skeleton without the production of acrylamide. Biodegradation.
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Marzena Hiler, Anna-Sophie Weidner, Lynn C Hull, Allison N Kurti & Elena V Mishina. (2023) Systemic biomarkers of exposure associated with ENDS use: a scoping review. Tobacco Control 32:4, pages 480-488.
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Shuai Wang, Yiyu Yang, Shulin Shan, Zhengcheng Huang, Zhaoxiong Liu, Hui Yong, Zhidan Liu, Cuiqin Zhang & Fuyong Song. (2023) Increased IP3R-3 degradation induced by acrylamide promoted Ca2+-dependent calpain activation and axon damage in rats. Toxicology Letters 383, pages 162-176.
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Pengcheng Pang, Xing Zhang, Jingping Yuan, Hong Yan & Dandan Yan. (2023) Acrylamide interferes with autophagy and induces apoptosis in Neuro-2a cells by interfering with TFEB-regulated lysosomal function. Food and Chemical Toxicology 177, pages 113818.
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Luanfeng Wang, Yanhong Liu, Huajing Gao, Shuqi Ge, Xinru Yao, Chang Liu & Xintong Tan. (2023) Chronotoxicity of Acrylamide in Mice Fed a High-Fat Diet: The Involvement of Liver CYP2E1 Upregulation and Gut Leakage. Molecules 28:13, pages 5132.
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Murat Kemal AVCI, Erdem TEZCAN, Safiye AVCI & Haluk CAMCI. (2023) Application of Linear Polyacrylamide (LPA) Matrix in Cotton Chromatin Immunoprecipitation to Increase Sheared DNA Isolation EfficiencyPamukta Kromatin İmmünopresipitasyon Yönteminde Kırpılmış DNA İzolasyon Verimini Arttırmak için Lineer Poliakrilamid (LPA) Matriksinin Uygulanması. Adnan Menderes Üniversitesi Ziraat Fakültesi Dergisi 20:1, pages 99-107.
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Shuai Wang, Yiyu Yang, Zhigang Yu, Mingxue Song, Zhidan Liu, Shulin Shan, Hui Yong, Wenting Ni, Yalong Qiang, Cuiqin Zhang, Shu’e Wang, Xiulan Zhao & Fuyong Song. (2023) Mitophagy suppresses motor neuron necroptotic mitochondrial damage and alleviates necroptosis that converges to SARM1 in acrylamide‐induced dying‐back neuropathy . Journal of Neurochemistry.
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D. Gündüz, H. Çetin & A.Ç. Dönmez. (2023) Investigation of the effects of swimming exercises in rats given acrylamide. Morphologie 107:357, pages 228-237.
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Xiaoyu Yan, Qiuju Li, Shuangyue Wu, Jie Liang, Yuanyuan Li, Tingting Zhang, Dayi Chen & Xiaoqi Pan. (2023) Acrylamide induces the activation of BV2 microglial cells through TLR2/4-mediated LRRK2-NFATc2 signaling cascade. Food and Chemical Toxicology 176, pages 113775.
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Yufei Pang, Jingxin Chen, Jianjun Yang, Yanzhong Xue, Hua Gao & Qinghan Gao. (2023) Protective effect and mechanism of Lycium ruthenicum polyphenols against acrylamide-induced neurotoxicity . Food & Function 14:10, pages 4552-4568.
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Listya Eka Anggraini, Isnaini Rahmawati, Mochammad Arfin Fardiansyah Nasution, Prastika Krisma Jiwanti, Yasuaki Einaga & Tribidasari Anggraningrum Ivandini. (2023) Development of an Acrylamide Biosensor using Guanine and Adenine as Biomarkers at Boron-doped Diamond Electrodes: An Integrated Molecular Docking and the Experimental Studies. Bulletin of the Chemical Society of Japan.
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Nicolas Pierre Friedrich Mueller, Paolo Carloni & Mercedes Alfonso-Prieto. (2023) Molecular determinants of acrylamide neurotoxicity through covalent docking. Frontiers in Pharmacology 14.
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Xiaofei Wang, Xiaowen Cheng, Huiling Liu, Xiaohuan Mu & Hao Zheng. (2023) Food nutrition and toxicology in the era of single-cell sequencing. Food Science and Human Wellness, pages 1-31.
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Tong Zhang, Chunmei Zhang, Yuyou Luo, Shuping Liu, Siyuan Li, Lixia Li, Yuxin Ma & Jing Liu. (2023) Protective effect of rutin on spinal motor neuron in rats exposed to acrylamide and the underlying mechanism. NeuroToxicology 95, pages 127-135.
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Rajesh L. Kachot, Urvesh D. Patel, Harshad B. Patel, Chirag M. Modi, RadheyShyam Chauhan, Mayank H. Kariya & Amit R. Bhadaniya. (2023) Neurotoxicity of acrylamide in adult zebrafish following short-term and long-term exposure: evaluation of behavior alterations, oxidative stress markers, expression of antioxidant genes, and histological examination of the brain and eyes. Environmental Science and Pollution Research 30:14, pages 40116-40131.
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Shuai Wang, Mingxue Song, Hui Yong, Cuiqin Zhang, Kang Kang, Zhidan Liu, Yiyu Yang, Zhengcheng Huang, Shu’e Wang, Haotong Ge, Xiulan Zhao & Fuyong Song. (2022) Mitochondrial Localization of SARM1 in Acrylamide Intoxication Induces Mitophagy and Limits Neuropathy. Molecular Neurobiology 59:12, pages 7337-7353.
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Falin He, Jinhu Wang, Dong Yuan, Yang Liu, Rutao Liu & Wansong Zong. (2022) Ferric ions release from iron-binding protein: Interaction between acrylamide and human serum transferrin and the underlying mechanisms of their binding. Science of The Total Environment 847, pages 157583.
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Yasemin Bicer, Hulya Elbe, Melike Karayakali, Gurkan Yigitturk, Umit Yilmaz, Osman Cengil, Mohammed Raed Abdullah Al Gburi & Eyup Altinoz. (2022) Neuroprotection by melatonin against acrylamide-induced brain damage in pinealectomized rats. Journal of Chemical Neuroanatomy 125, pages 102143.
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Ying Liu, Yiqi Wang, Xing Zhang, Yang Jiao, Lian Duan, Lingling Dai & Hong Yan. (2022) Chronic acrylamide exposure resulted in dopaminergic neuron loss, neuroinflammation and motor impairment in rats. Toxicology and Applied Pharmacology 451, pages 116190.
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Zizhuang Fang, Yinghua Luo, Chen Ma, Li Dong & Fang Chen. (2022) Blueberry Anthocyanins Extract Attenuates Acrylamide-Induced Oxidative Stress and Neuroinflammation in Rats. Oxidative Medicine and Cellular Longevity 2022, pages 1-16.
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Dandan Yan, Na Wang, Jianling Yao, Xu Wu, Jingping Yuan & Hong Yan. (2022) Curcumin Attenuates the PERK-eIF2α Signaling to Relieve Acrylamide-Induced Neurotoxicity in SH‑SY5Y Neuroblastoma Cells. Neurochemical Research 47:4, pages 1037-1048.
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Hang Zhang, Lidong Shan, Stanley Aniagu, Yan Jiang & Tao Chen. (2022) Paternal acrylamide exposure induces transgenerational effects on sperm parameters and learning capability in mice. Food and Chemical Toxicology 161, pages 112817.
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Doaa M. Hassan, Nermeen N. Welson & Hanan D. Yassa. (2021) The Possible Protective Role of Dark Chocolate Against Acrylamide Neurotoxicity in Weaning Rats Cerebellum. Molecular Neurobiology 59:1, pages 234-244.
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