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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 17, 2014 - Issue 4
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Original Research Papers

Kenyan purple tea anthocyanins ability to cross the blood brain barrier and reinforce brain antioxidant capacity in mice

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Hao Tang, Jinchi Tang, Jiayu Liu, Bo Zhou & Yiyong Chen. (2021) Metabolomics analyses reveal anthocyanins-rich accumulation in naturally mutated purple-leaf tea (Camellia sinensis L.). All Life 14:1, pages 744-755.
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Gaozhong Yang, Qing Meng, Jiang Shi, Mengxue Zhou, Yin Zhu, Qiushuang You, Ping Xu, Wenliang Wu, Zhi Lin & Haipeng Lv. (2023) Special tea products featuring functional components: Health benefits and processing strategies. Comprehensive Reviews in Food Science and Food Safety 22:3, pages 1686-1721.
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Cristiane de Moura, Tufy Kabbas Junior, Thiago Mendanha Cruz, Mariza Boscacci Marques, Mariana Araújo Vieira do Carmo, Carolina Turnes Pasini Deolindo, Heitor Daguer, Luciana Azevedo, Yong-Quan Xu & Daniel Granato. (2023) Sustainable and effective approach to recover antioxidant compounds from purple tea (Camellia sinensis var. assamica cv. Zijuan) leaves. Food Research International 164, pages 112402.
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Hao Zhong, Jie Xu, Mengyu Yang, Muhammad Hussain, Xiaofeng Liu, Fengqin Feng & Rongfa Guan. (2023) Protective Effect of Anthocyanins against Neurodegenerative Diseases through the Microbial-Intestinal-Brain Axis: A Critical Review. Nutrients 15:3, pages 496.
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Agnieszka Micek, Marcin Owczarek, Joanna Jurek, Ida Guerrera, Sebastiano Alfio Torrisi, Giuseppe Grosso, Ali A. Alshatwi & Justyna Godos. (2022) Anthocyanin-rich fruits and mental health outcomes in an Italian cohort. Journal of Berry Research 12:4, pages 551-564.
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Feiyi Huang, Jihua Duan, Yu Lei, Yankai Kang, Yi Luo, Yingyu Chen, Ding Ding & Saijun Li. (2022) Metabolomic and transcriptomic analyses reveal a MYB gene, CsAN1, involved in anthocyanins accumulation separation in F1 between ‘Zijuan’ (Camellia sinensis var. assamica) and ‘Fudingdabaicha’ (C. sinensis var. sinensis) tea plants. Frontiers in Plant Science 13.
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Sanjay, Jae-Ho Shin, Miey Park & Hae-Jeung Lee. (2022) Cyanidin-3-O-Glucoside Regulates the M1/M2 Polarization of Microglia via PPARγ and Aβ42 Phagocytosis Through TREM2 in an Alzheimer’s Disease Model. Molecular Neurobiology 59:8, pages 5135-5148.
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Zhihui Wang, Puxiang Yang, Hua Peng, Wenjin Li, Cuinan Yue & Chen Li. (2022) Analysis of quality-related nonvolatile metabolites in tea (Camellia sinensis) resources with different shoot colors. European Journal of Horticultural Science 87:2.
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Chi-Chang Chang, Jer-Yiing Houng, Wei-Hao Peng, Tien-Wei Yeh, Yun-Ya Wang, Ya-Ling Chen, Tzu-Hsien Chang, Wei-Chin Hung & Teng-Hung Yu. (2022) Effects of Abelmoschus manihot Flower Extract on Enhancing Sexual Arousal and Reproductive Performance in Zebrafish. Molecules 27:7, pages 2218.
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Asif Husain, Harshit Chanana, Shah Alam Khan, U. M. Dhanalekshmi, M. Ali, Anwar A. Alghamdi & Aftab Ahmad. (2022) Chemistry and Pharmacological Actions of Delphinidin, a Dietary Purple Pigment in Anthocyanidin and Anthocyanin Forms. Frontiers in Nutrition 9.
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Urszula Trych, Magdalena Buniowska, Sylwia Skąpska, Ireneusz Kapusta & Krystian Marszałek. (2022) Bioaccessibility of Antioxidants in Blackcurrant Juice after Treatment Using Supercritical Carbon Dioxide. Molecules 27:3, pages 1036.
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Xuqiu He, Ronghao Huang, Lipeng Liu, Yingying Li, Wenzhao Wang, Qingshan Xu, Youben Yu & Tianshan Zhou. (2021) CsUGT78A15 catalyzes the anthocyanidin 3-O-galactoside biosynthesis in tea plants. Plant Physiology and Biochemistry 166, pages 738-749.
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Francis Gitonga, Kipchumba Biwott, Grace Wairimu Gitau, Okanya Patrick Wafula, Amwayi Peris Wanza, Isaac Orina Alfred & Nyariki James Nyabuga. (2021) Coenzyme Q10 Ameliorates Potassium Cyanide-Induced Toxicosis in a Mouse Model. Scientific African, pages e00815.
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Fanghua Guo, Rong Tsao, Xiaoya Wang, Li Jiang, Yong Sun & Hua Xiong. (2021) Phenolics of Yellow Pea ( Pisum sativum L.) Hulls, Their Plasma and Urinary Metabolites, Organ Distribution, and In Vivo Antioxidant Activities . Journal of Agricultural and Food Chemistry 69:17, pages 5013-5025.
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Roger Gaudreault, Vincent Hervé, Theo G.M. van de Ven, Normand Mousseau & Charles Ramassamy. (2021) Polyphenol-Peptide Interactions in Mitigation of Alzheimer’s Disease: Role of Biosurface-Induced Aggregation. Journal of Alzheimer's Disease 81:1, pages 33-55.
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Wenjia He, Zhucheng Yin, Shuxun Liu, Yao Chen, Xuejiao Qie, Jie Chen, Maomao Zeng, Fang Qin & Zhiyong He. (2021) Effect of preheated milk proteins and bioactive compounds on the stability of cyanidin-3-O-glucoside. Food Chemistry 345, pages 128829.
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Navrinder Kaur, Heerak Chugh, Meena K. Sakharkar, Uma Dhawan, Saravana Babu Chidambaram & Ramesh Chandra. (2020) Neuroinflammation Mechanisms and Phytotherapeutic Intervention: A Systematic Review. ACS Chemical Neuroscience 11:22, pages 3707-3731.
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Li‐Qiang Tan, Chun‐Jing Yang, Bin Zhou, Liu‐Bin Wang, Yao Zou, Wei Chen, Tao Xia & Qian Tang. (2020) Inheritance and quantitative trait loci analyses of the anthocyanins and catechins of Camellia sinensis cultivar ‘Ziyan’ with dark‐purple leaves . Physiologia Plantarum 170:1, pages 109-119.
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Guillermo Cásedas, Francisco Les & Víctor López. (2020) Anthocyanins: Plant Pigments, Food Ingredients or Therapeutic Agents for the CNS? A Mini-Review Focused on Clinical Trials. Current Pharmaceutical Design 26:16, pages 1790-1798.
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Patricia Sanmartín, Michela Gambino, Elsa Fuentes & Miguel Serrano. (2020) A Simple, Reliable, and Inexpensive Solution for Contact Color Measurement in Small Plant Samples. Sensors 20:8, pages 2348.
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Wei Li, Liqiang Tan, Yao Zou, Xiaoqin Tan, Jiacheng Huang, Wei Chen & Qian Tang. (2020) The Effects of Ultraviolet A/B Treatments on Anthocyanin Accumulation and Gene Expression in Dark-Purple Tea Cultivar ‘Ziyan’ (Camellia sinensis). Molecules 25:2, pages 354.
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Keuri Eleutério Rodrigues, Fábio Rodrigues de Oliveira, Benilson Ramos Cassunde Barbosa, Ricardo S. Oliveira Paraense, Cahy Manoel Bannwart, Bruno Gonçalves Pinheiro, Anderson de Santana Botelho, Nilton Akio Muto, Cristine Bastos do Amarante, Moises Hamoy, Barbarella de Matos Macchi, Cristiane do Socorro Ferraz Maia, Alejandro Ferraz do Prado & José Luiz Martins do Nascimento. (2019) Aqueous Coriandrum sativum L. extract promotes neuroprotection against motor changes and oxidative damage in rat progeny after maternal exposure to methylmercury. Food and Chemical Toxicology 133, pages 110755.
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Jinlin Zhang, Jingjing Wu, Fengguo Liu, Lijuan Tong, Zhuo Chen, Jinliang Chen, Haiyan He, Rong Xu, Yaoying Ma & Chao Huang. (2019) Neuroprotective effects of anthocyanins and its major component cyanidin-3-O-glucoside (C3G) in the central nervous system: An outlined review. European Journal of Pharmacology 858, pages 172500.
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Tracy Bariexca, Janice Ezdebski, Benjamin Redan & Joe Vinson. (2019) Pure Polyphenols and Cranberry Juice High in Anthocyanins Increase Antioxidant Capacity in Animal Organs. Foods 8:8, pages 340.
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James N. Nyariki, Lucy A. Ochola, Ngalla E. Jillani, Nemwel O. Nyamweya, Peris E. Amwayi, Dorcas S. Yole, Laurent Azonvide & Alfred Orina Isaac. (2019) Oral administration of Coenzyme Q10 protects mice against oxidative stress and neuro-inflammation during experimental cerebral malaria. Parasitology International 71, pages 106-120.
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Manolescu, Oprea, Mititelu, Ruta & Farcasanu. (2019) Dietary Anthocyanins and Stroke: A Review of Pharmacokinetic and Pharmacodynamic Studies. Nutrients 11:7, pages 1479.
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Lingshuai Meng, Guang Xin, Bin Li, Dongnan Li, Xiyun Sun, Tingcai Yan, Li Li, Lin Shi, Sen Cao & Xianjun Meng. (2018) Anthocyanins Extracted from Aronia melanocarpa Protect SH-SY5Y Cells against Amyloid-beta (1–42)-Induced Apoptosis by Regulating Ca 2+ Homeostasis and Inhibiting Mitochondrial Dysfunction . Journal of Agricultural and Food Chemistry 66:49, pages 12967-12977.
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Berner Andrée Sandoval-Ramírez, Úrsula Catalán, Sara Fernández-Castillejo, Laura Rubió, Alba Macià & Rosa Solà. (2018) Anthocyanin Tissue Bioavailability in Animals: Possible Implications for Human Health. A Systematic Review. Journal of Agricultural and Food Chemistry 66:44, pages 11531-11543.
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M. Gill, A. Rai, M. Kinra, S. Sumalatha, C. M. Rao, S. P. Cheruku, R. Devkar & N. Kumar. (2018) Chemically characterised extract of Saraca asoca improves the sexual function in male Wistar rats . Andrologia 50:7, pages e13037.
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Qiongqiong Zhou, Zhidan Chen, Jinwook Lee, Xinghui Li & Weijiang Sun. (2017) Proteomic analysis of tea plants (Camellia sinensis) with purple young shoots during leaf development. PLOS ONE 12:5, pages e0177816.
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Amira Ouanouki, Sylvie Lamy & Borhane Annabi. (2017) Anthocyanidins inhibit epithelial-mesenchymal transition through a TGF?/Smad2 signaling pathway in glioblastoma cells. Molecular Carcinogenesis 56:3, pages 1088-1099.
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Kang Wei, Yazhen Zhang, Liyun Wu, Hailin Li, Li Ruan, Peixian Bai, Chengcai Zhang, Fen Zhang, Liyi Xu, Liyuan Wang & Hao Cheng. (2016) Gene expression analysis of bud and leaf color in tea. Plant Physiology and Biochemistry 107, pages 310-318.
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S O Ochanda, K Rashid, J K Wanyoko, M Ngotho, A K Faraj, C A Onyango, F N Wachira & D N Maranga. (2016) Fortification of alcoholic beverages (12% v/v) with tea ( Camellia sinensis ) reduces harmful effects of alcohol ingestion and metabolism in mouse model . BMJ Open Gastroenterology 3:1, pages e000058.
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Abdenour Belkacemi & Charles Ramassamy. (2016) Anthocyanins Protect SK-N-SH Cells Against Acrolein-Induced Toxicity by Preserving the Cellular Redox State. Journal of Alzheimer's Disease 50:4, pages 981-998.
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Wei He, Maomao Zeng, Jie Chen, Yuzhi Jiao, Fuxiang Niu, Guanjun Tao, Shuang Zhang, Fang Qin & Zhiyong He. (2015) Identification and Quantitation of Anthocyanins in Purple-Fleshed Sweet Potatoes Cultivated in China by UPLC-PDA and UPLC-QTOF-MS/MS. Journal of Agricultural and Food Chemistry 64:1, pages 171-177.
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Samuel Kimutai, John Wanyoko, Thomas Kinyanjui, Stephen Karori, Augustine Muthiani & Francis Wachira. (2016) Determination of Residual Catechins, Polyphenolic Contents and Antioxidant Activities of Developed Theaflavin-3,3’-Digallate Rich Black Teas. Food and Nutrition Sciences 07:03, pages 180-191.
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R.N. Gacche, R.J. Meshram, H.D. Shegokar, D.S. Gond, S.S. Kamble, V.N. Dhabadge, B.G. Utage, K.K. Patil & R.A. More. (2015) Flavonoids as a scaffold for development of novel anti-angiogenic agents: An experimental and computational enquiry. Archives of Biochemistry and Biophysics 577-578, pages 35-48.
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