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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 19, 2016 - Issue 6
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Original research paper

Tannoid principles of Emblica officinalis renovate cognitive deficits and attenuate amyloid pathologies against aluminum chloride induced rat model of Alzheimer's disease

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Hesham N. Mustafa. (2020) Neuro-amelioration of cinnamaldehyde in aluminum-induced Alzheimer’s disease rat model. Journal of Histotechnology 43:1, pages 11-20.
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Arpita Devi, S. Chennakesavulu, Chava Suresh & Aramati B. M. Reddy. 2018. Functional Food and Human Health. Functional Food and Human Health 375 403 .
Li Tian, Chin Wai Hui, Kanchan Bisht, Yunlong Tan, Kaushik Sharma, Song Chen, Xiangyang Zhang & Marie-Eve Tremblay. (2017) Microglia under psychosocial stressors along the aging trajectory: Consequences on neuronal circuits, behavior, and brain diseases. Progress in Neuro-Psychopharmacology and Biological Psychiatry 79, pages 27-39.
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Yunpeng Wei, Dan Liu, Yin Zheng, Honglian Li, Chaoshuang Hao & Wuqing Ouyang. (2017) Protective effects of kinetin against aluminum chloride and D-galactose induced cognitive impairment and oxidative damage in mouse. Brain Research Bulletin 134, pages 262-272.
Crossref
Ali Rafati, Nasrin Nourzei, Saied Karbalay-Doust & Ali Noorafshan. (2017) Using vitamin E to prevent the impairment in behavioral test, cell loss and dendrite changes in medial prefrontal cortex induced by tartrazine in rats. Acta Histochemica 119:2, pages 172-180.
Crossref
Muhammad Akram & Allah Nawaz. (2017) Effects of medicinal plants on Alzheimer's disease and memory deficits. Neural Regeneration Research 12:4, pages 660.
Crossref
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Crossref
Bhavesh C. Variya, Anita K. Bakrania & Snehal S. Patel. (2016) Emblica officinalis (Amla): A review for its phytochemistry, ethnomedicinal uses and medicinal potentials with respect to molecular mechanisms. Pharmacological Research 111, pages 180-200.
Crossref
Pranay Srivastava & Rajesh Singh Yadav. 2016. The Benefits of Natural Products for Neurodegenerative Diseases. The Benefits of Natural Products for Neurodegenerative Diseases 107 123 .

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