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Maylin Wong-Guerra, Javier Jiménez-Martin, Luis Arturo Fonseca-Fonseca, Jeney Ramírez-Sánchez, Yanay Montano-Peguero, Joao Batista Rocha, Fernanda D´Avila, Adriano M. de Assis, Diogo Onofre Souza, Gilberto L. Pardo-Andreu, Roberto Menéndez-Soto del Valle, Guillermo Aparicio Lopez, Odalys Valdés Martínez, Nelson Merino García, Abel Mondelo-Rodríguez, Alejandro Saúl Padrón-Yaquis & Yanier Nuñez-Figueredo. (2019) JM-20 protects memory acquisition and consolidation on scopolamine model of cognitive impairment. Neurological Research 41:5, pages 385-398.
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Aline Franzen da Silva, Larissa Marafiga Cordeiro, Marcell Vallandro Soares, Danielle Coradini Zamberlan, Fabiane Bicca Obetine Baptista, Tássia Limana da Silveira, Marina Lopes Machado, Leticia Priscilla Arantes, Yanier Nuñez-Figueredo, Estael Ochoa Rodríguez & Félix Alexandre Antunes Soares. (2022) JM-20 affects GABA neurotransmission in Caenorhabditis elegans. NeuroToxicology 93, pages 37-44.
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Cleonice Creusa Santos, Thyago R. Cardim-Pires, Liana Shvachiy, Luis Arturo Fonseca-Fonseca, Patricia Muñoz, Áurea Maria A. N. Almeida, Ana Carla S. Costa, Jéssica Teles-Souza, Estael Ochoa-Rodríguez, Maria de Fátima Dias Costa, Fernando L. Palhano, Juan Segura-Aguilar, Deyse B. Barbosa, Mayra R. do Bomfim, Manoelito C. dos Santos Junior, Franco Henrique A. Leite, Samuel Silva da Rocha Pita, Silvia Lima Costa, Yanier Núñez-Figueredo, Tiago Fleming Outeiro, Débora Foguel & Victor Diogenes Amaral Silva. (2022) JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species. Neurotoxicity Research 40:6, pages 2135-2147.
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Claudia Miranda, Alejandro Ruiz-Picazo, Paula Pomares, Isabel Gonzalez-Alvarez, Marival Bermejo, Marta Gonzalez-Alvarez, Alex Avdeef & Miguel-Ángel Cabrera-Pérez. (2022) Integration of In Silico, In Vitro and In Situ Tools for the Preformulation and Characterization of a Novel Cardio-Neuroprotective Compound during the Early Stages of Drug Development. Pharmaceutics 14:1, pages 182.
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Maylin Wong-Guerra, Yanay Montano-Peguero, Jeney Ramírez-Sánchez, Javier Jiménez-Martin, Luis Arturo Fonseca-Fonseca, Daniela Hernández-Enseñat, Yasmine Nonose, Odalys Valdés, Abel Mondelo-Rodriguez, Yaquelin Ortiz-Miranda, Gretchen Bergado, Tania Carmenate, Roberto Menéndez Soto del Valle, Gilberto Pardo-Andreu, Tiago Fleming Outeiro, Alejandro Saúl Padrón-Yaquis, Adriano Martimbianco de Assis, Diogo O Souza & Yanier Nuñez-Figueredo. (2021) JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats. NeuroToxicology 87, pages 70-85.
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Andrezza Bond Vieira Furtado, Debora Farina Gonçalves, Diane Duarte Hartmann, Aline Alves Courtes, Gustavo Cassol, Yanier Nunez-Figueredo, Deivison Silva Argolo, Ravena Pereira do Nascimento, Silvia Lima Costa, Victor Diogenes Amaral da Silva, Luiz Fernando Freire Royes & Félix Alexandre Antunes Soares. (2021) JM-20 Treatment After Mild Traumatic Brain Injury Reduces Glial Cell Pro-inflammatory Signaling and Behavioral and Cognitive Deficits by Increasing Neurotrophin Expression. Molecular Neurobiology 58:9, pages 4615-4627.
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Luis Arturo Fonseca-Fonseca, Víctor Diogenes Amaral da Silva, Maylin Wong-Guerra, Jeney Ramírez-Sánchez, Alejandro Saúl Padrón Yaquis, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, Fillipe Mendes de Araújo, Rejane Conceição Santana, Tiago Fleming Outeiro, Silvia Lima Costa & Yanier Núñez-Figueredo. (2021) JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties. NeuroToxicology 82, pages 89-98.
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Bárbara B. Garrido-Suárez, Gabino Garrido, Marian Castro-Labrada, Nelson Merino, Odalys Valdés, Zenia Pardo, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, René Delgado-Hernández, Jozi Godoy-Figueiredo & Sergio H. Ferreira. (2020) Anti-hypernociceptive and anti-inflammatory effects of JM-20: A novel hybrid neuroprotective compound. Brain Research Bulletin 165, pages 185-197.
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Fernanda D’Avila da Silva, Pablo Andrei Nogara, Estael Ochoa-Rodríguez, Yanier Nuñez-Figueredo, Maylin Wong-Guerra, Denis Broock Rosemberg & João Batista Teixeira da Rocha. (2020) Molecular docking and in vitro evaluation of a new hybrid molecule (JM-20) on cholinesterase activity from different sources. Biochimie 168, pages 297-306.
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Quelen Iane Garlet, Patrícia Rodrigues, Luísa Barichello Barbosa, André Luís Londero, Carlos Fernando Mello & Berta Maria Heinzmann. (2019) Nectandra grandiflora essential oil and its isolated sesquiterpenoids minimize anxiety-related behaviors in mice through GABAergic mechanisms. Toxicology and Applied Pharmacology 375, pages 64-80.
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Luis Arturo Fonseca-Fonseca, Maylin Wong-Guerra, Jeney Ramírez-Sánchez, Yanay Montano-Peguero, Alejandro Saúl Padrón Yaquis, Abel Mondelo Rodríguez, Víctor Diógenes Amaral da Silva, Silvia Lima Costa, Gilberto L. Pardo-Andreu & Yanier Núñez-Figueredo. (2019) JM-20, a novel hybrid molecule, protects against rotenone-induced neurotoxicity in experimental model of Parkinson’s disease. Neuroscience Letters 690, pages 29-35.
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Jeney Ramírez-Sánchez, Elisa Nicoloso Simões Pires, André Meneghetti, Gisele Hansel, Yanier Nuñez-Figueredo, Gilberto L. Pardo-Andreu, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, René Delgado-Hernández, Christianne Salbego & Diogo O Souza. (2018) JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain. Molecular Neurobiology 56:1, pages 502-512.
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Yanier Nuñez-Figueredo, Jeney Ramírez-Sánchez, Gilberto L. Pardo Andreu, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes & Diogo O. Souza. (2018) Multi-targeting effects of a new synthetic molecule (JM-20) in experimental models of cerebral ischemia. Pharmacological Reports 70:4, pages 699-704.
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Luana C. Santos, Julia Ruiz-Oliveira, Priscila F. Silva & Ana C. Luchiari. 2017. The Question of Caffeine. The Question of Caffeine.
Jeney Ramírez-Sánchez, Elisa Nicoloso Simões Pires, Yanier Nuñez-Figueredo, Gilberto L. Pardo-Andreu, Luis Arturo Fonseca-Fonseca, Alberto Ruiz-Reyes, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, René Delgado-Hernández, Diogo O. Souza & Christianne Salbego. (2015) Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway. Neurochemistry International 90, pages 215-223.
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Yanier Nuñez-Figueredo, Gilberto L. Pardo Andreu, Samanta Oliveira Loureiro, Marcelo Ganzella, Jeney Ramírez-Sánchez, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, René Delgado-Hernández & Diogo O. Souza. (2015) The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain. Neurochemistry International 81, pages 41-47.
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Eduardo Ramírez-San Juan, Marvin A. Soriano-Ursúa, Judith Espinosa-Raya, José Correa-Basurto, José G. Trujillo-Ferrara, René Miranda-Ruvalcaba, Francisco Delgado-Reyes & Raquel Gómez-Pliego. (2014) Anticonvulsant effects of bis-1,4-dihydropyridines and the probable role of L-type calcium channels suggested by docking simulations. Medicinal Chemistry Research 23:12, pages 5149-5159.
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Yanier Nuñez-Figueredo, Jeney Ramírez-Sánchez, Gisele Hansel, Elisa Nicoloso Simões Pires, Nelson Merino, Odalys Valdes, René Delgado-Hernández, Alicia Lagarto Parra, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, Christianne Salbego, Silvia L. Costa, Diogo O. Souza & Gilberto L. Pardo-Andreu. (2014) A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo. Neuropharmacology 85, pages 517-527.
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Yanier Nuñez-Figueredo, Gilberto L. Pardo-Andreu, Jeney Ramírez-Sánchez, René Delgado-Hernández, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, Zeki Naal, Alexandre Pastoris Muller, Luis Valmor Portela & Diogo O. Souza. (2014) Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca2+-induced mitochondrial impairment. Brain Research Bulletin 109, pages 68-76.
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Yanier Nuñez-Figueredo, Jeney Ramírez-Sánchez, René Delgado-Hernández, Marlene Porto-Verdecia, Estael Ochoa-Rodríguez, Yamila Verdecia-Reyes, Javier Marin-Prida, Michael González-Durruthy, Sergio A. Uyemura, Fernando P. Rodrigues, Carlos Curti, Diogo O. Souza & Gilberto L. Pardo-Andreu. (2014) JM-20, a novel benzodiazepine–dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro. European Journal of Pharmacology 726, pages 57-65.
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