Advanced search
Publication Cover
Redox Report
Communications in Free Radical Research
Volume 16, 2011 - Issue 2
Submit an article Journal homepage
815
Views
25
CrossRef citations to date
0
Altmetric
Research article

Hepatoprotective effects of saponarin, isolated from Gypsophila trichotoma Wend. on cocaine-induced oxidative stress in rats

Vessela VitchevaLaboratory of Drug Metabolism and Drug ToxicityDepartment of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University, Sofia, BulgariaCorrespondence[email protected]
,
Rumyana SimeonovaLaboratory of Drug Metabolism and Drug ToxicityDepartment of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University, Sofia, Bulgaria
,
Ilina KrastevaDepartment of PharmacognosyFaculty of Pharmacy, Medical University, Sofia, Bulgaria
,
Maya YotovaDepartment of PharmacognosyFaculty of Pharmacy, Medical University, Sofia, Bulgaria
,
Stefan NikolovDepartment of PharmacognosyFaculty of Pharmacy, Medical University, Sofia, Bulgaria
&
Mitka MitchevaLaboratory of Drug Metabolism and Drug ToxicityDepartment of Pharmacology, Pharmacotherapy and Toxicology, Faculty of Pharmacy, Medical University, Sofia, Bulgaria
Pages 56-61 | Published online: 19 Jul 2013

Citations (25)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Navneet Kumar, RaosahebK. Kale & AshuB. Tiku. (2013) Chemopreventive Effect of Lagenaria siceraria in Two Stages DMBA Plus Croton Oil Induced Skin Papillomagenesis. Nutrition and Cancer 65:7, pages 991-1001.
Read now

Articles from other publishers (24)

Jun Chang, Shaoqing Zou, Subo Xu, Yiwen Xiao & Du Zhu. (2024) Screening of Inhibitors against Idiopathic Pulmonary Fibrosis: Few-shot Machine Learning and Molecule Docking based Drug Repurposing. Current Computer-Aided Drug Design 20:2, pages 134-144.
Crossref
Na Shen, Yuanrong Li, Yanxia Liu, Yao Liu, Huawei Xin & Yulei Cui. (2023) Gypsophila oldhamiana leaves as a potential industrial resource of lipids, alkaloids, flavonoids and anti-osteoporosis components. Industrial Crops and Products 196, pages 116510.
Crossref
Bojana Dimitrova, Rumyana Vitanska, Reneta Gevrenova, Dimitrina Zheleva-Dimitrova, Vessela Balabanova & Stoycho Stoev. (2022) Molecular networking-assisted flavonoid profile of Gypsophila glomerata extract in relation to its protective effects on carbon tetrachloride-induced hepatorenal damage in rats . Acta Pharmaceutica 72:1, pages 59-77.
Crossref
Katarzyna Jakimiuk, Michael Wink & Michał Tomczyk. (2021) Flavonoids of the Caryophyllaceae. Phytochemistry Reviews 21:1, pages 179-218.
Crossref
Reneta Gevrenova, Gokhan Zengin, Vessela Balabanova, Yulian Voynikov & Dimitrina Zheleva-Dimitrova. (2021) C, O – flavonoid glycosides and oleanane-type bidesmosides from Gypsophila perfoliata L. “tekirae” (Caryophyllaceae): Chemophenetic implications. Biochemical Systematics and Ecology 99, pages 104353.
Crossref
Samson E. Abalaka, Fatima O. Oyelowo, Motunrayo G. Akande, Oremeyi Z. Tenuche, Nuhu A. Sani, Bolade T. Adeyemo, Idoko S. Idoko, Adamu O. Ogbe & Sunday A. Ejeh. (2021) Effects of Moringa oleifera leaves extract, vitamin C, and taurine co-exposures on calcium and metallothionein levels, oxidative stress, and gill histopathological changes in Clarias gariepinus exposed to sub-lethal cadmium. Environmental Science and Pollution Research 28:37, pages 52258-52271.
Crossref
Myeong-Jin Kim, Hye-Won Kawk, Sang-Hyeon Kim, Hyo-Jae Lee, Ji-Won Seo, Jong-Tae Kim, Seung-Hee Jang, Min-Jeong Kim & Young-Min Kim. (2021) Anti-Obesity Effect of Hot Water Extract of Barley Sprout through the Inhibition of Adipocyte Differentiation and Growth. Metabolites 11:9, pages 610.
Crossref
Hyerin Park, Eunok Lee, Yunsoo Kim, Hye Yoon Jung, Kwang-Min Kim & Oran Kwon. (2021) Metabolic Profiling Analysis Reveals the Potential Contribution of Barley Sprouts against Oxidative Stress and Related Liver Cell Damage in Habitual Alcohol Drinkers. Antioxidants 10:3, pages 459.
Crossref
Nam-Jin Chung, Jun-Young Kim, Yuna Lee, So-Hee Shin, Jeong-Sup Song, Sung Chul Shin & Beom-Tae Kim. (2019) Variations of Saponarin Content in Young Barley Leaves Illuminated with Different Light-Emitting Diodes (LEDs). Journal of Crop Science and Biotechnology 22:4, pages 317-322.
Crossref
Imen Bouhaouel, Gaëtan Richard, Marie-Laure Fauconnier, Marc Ongena, Laurent Franzil, Aurélie Gfeller, Hajer Slim Amara & Patrick du Jardin. (2019) Identification of Barley (Hordeum vulgare L. subsp. vulgare) Root Exudates Allelochemicals, Their Autoallelopathic Activity and Against Bromus diandrus Roth. Germination. Agronomy 9:7, pages 345.
Crossref
Maged Mohamed Abd-Elhaki, Noha Ahmed El-B, Ebtehal Kamal Eldi, Ataa Abdelhalim & Sylvia Edward Sha. (2019) Protective and Curative Effects of Bombax ceiba Flower and Ziziphus spina christi Fruit Extracts on Gastric Ulcer. Journal of Biological Sciences 19:2, pages 161-172.
Crossref
Huynh Nhu Mai, Sung Hoon Lee, Garima Sharma, Dae-Joong Kim, Naveen Sharma, Eun-Joo Shin, Duc Toan Pham, Quynh Dieu Trinh, Choon-Gon Jang, Seung-Yeol Nah, Ji Hoon Jeong & Hyoung-Chun Kim. (2019) Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. Chemico-Biological Interactions 297, pages 95-108.
Crossref
Ahmet Altay, Sebnem Degirmenci, Mustafa Korkmaz, Murat Cankaya & Ekrem Koksal. (2018) In vitro evaluation of antioxidant and anti-proliferative activities of Gypsophila sphaerocephala (Caryophyllaceae) extracts together with their phenolic profiles. Journal of Food Measurement and Characterization 12:4, pages 2936-2945.
Crossref
Ahmet ALTAY. (2018) HPLC Analysis of Phenolic Compounds from Gypsophila aucheri Boiss. and Investigation of Antioxidant and Cytotoxic Activity of Gypsophila aucheri Boiss. exractsHPLC Analysis of Phenolic Compounds from Gypsophila aucheri Boiss. and Investigation of Antioxidant and Cytotoxic Activity of Gypsophila aucheri Boiss. exracts. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi 11:2, pages 168-181.
Crossref
Dimitrina Zheleva-Dimitrova, Gokhan Zengin, Vessela Balabanova, Yulian Voynikov, Valentin Lozanov, Irina Lazarova & Reneta Gevrenova. (2018) Chemical characterization with in vitro biological activities of Gypsophila species. Journal of Pharmaceutical and Biomedical Analysis 155, pages 56-69.
Crossref
Yun-Hee Lee, Joung-Hee Kim, Sou Kim, Ji Oh, Woo Seo, Kyung-Mi Kim, Jae-Chul Jung & Young-Suk Jung. (2016) Barley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response. Nutrients 8:7, pages 440.
Crossref
Rumyana Simeonova, Vessela Vitcheva, Ilina Krasteva, Petranka Zdraveva, Spiro Konstantinov & Iliana Ionkova. (2016) Antidiabetic and antioxidant effects of saponarin from Gypsophila trichotoma on streptozotocin-induced diabetic normotensive and hypertensive rats. Phytomedicine 23:5, pages 483-490.
Crossref
Safiye Emirdağ-Öztürk, İlknur Babahan & Ali Özmen. (2014) Synthesis, characterization and in vitro anti-neoplastic activity of gypsogenin derivatives. Bioorganic Chemistry 53, pages 15-23.
Crossref
Navdeep K. Chima, Lutfun Nahar, Runner R.T. Majinda, Sezgin Celik & Satyajit D. Sarker. (2014) Assessment of free-radical scavenging activity of Gypsophila pilulifera: assay-guided isolation of verbascoside as the main active component. Revista Brasileira de Farmacognosia 24:1, pages 38-43.
Crossref
Rumyana Simeonova, Magdalena Kondeva-Burdina, Vessela Vitcheva & Mitka Mitcheva. (2014) Some In Vitro/In Vivo Chemically-Induced Experimental Models of Liver Oxidative Stress in Rats . BioMed Research International 2014, pages 1-6.
Crossref
Kyung Hye Seo, Mi Jin Park, Ji-Eun Ra, Sang-Ik Han, Min-Hee Nam, Jin Hyo Kim, Jin Hwan Lee & Woo Duck Seo. (2014) Saponarin from barley sprouts inhibits NF-κB and MAPK on LPS-induced RAW 264.7 cells. Food Funct. 5:11, pages 3005-3013.
Crossref
Rumyana Simeonova, Magdalena Kondeva-Burdina, Vessela Vitcheva, Ilina Krasteva, Vassil Manov & Mitka Mitcheva. (2014) Protective effects of the apigenin-O/C-diglucoside saponarin from Gypsophila trichotoma on carbone tetrachloride-induced hepatotoxicity in vitro/in vivo in rats. Phytomedicine 21:2, pages 148-154.
Crossref
Rumyana Simeonova, Vessela Vitcheva, Magdalena Kondeva-Burdina, Ilina Krasteva, Vassil Manov & Mitka Mitcheva. (2013) Hepatoprotective and Antioxidant Effects of Saponarin, Isolated from Gypsophila trichotoma Wend. on Paracetamol-Induced Liver Damage in Rats . BioMed Research International 2013, pages 1-10.
Crossref
Vartika Jain & Surendra K. VermaVartika Jain & Surendra K. Verma. 2012. Pharmacology of Bombax ceiba Linn.. Pharmacology of Bombax ceiba Linn. 25 50 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.