Advanced search
Publication Cover
Journal of Chemotherapy Volume 25, 2013 - Issue 1
Submit an article Journal homepage
2,666
Views
60
CrossRef citations to date
0
Altmetric
Review

Carbapenems

Dominique BreilhLaboratory of Clinical Pharmacokinetics and Clinical Pharmacy INSERM U1034, Haut-Lévêque hospital, CHU Bordeaux, University of Bordeaux, Segalen, Pessac, FranceCorrespondence[email protected]
,
Jeannette Texier-MaugeinBacteriology Haut-Lévêque hospital, CHU Bordeaux, University of Bordeaux, Segalen, Pessac, France
,
Bernard Allaouchiche Department of Anesthesiology and Intensive CareÉdouard Herriot hospital, HCL, University of Lyon, Lyon, France
,
Marie-Claude SauxLaboratory of Clinical Pharmacokinetics and Clinical Pharmacy INSERM U1034, Haut-Lévêque hospital, CHU Bordeaux, University of Bordeaux, Segalen, Pessac, France
&
Emmanuel BoselliLaboratory of Clinical Pharmacokinetics and Clinical Pharmacy INSERM U1034, Haut-Lévêque hospital, CHU Bordeaux, University of Bordeaux, Segalen, Pessac, France; Department of Anesthesiology and Intensive CareÉdouard Herriot hospital, HCL, University of Lyon, Lyon, France
Pages 1-17 | Published online: 12 Nov 2013

Citations (60)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Tahisa Marcela Pedroso & Hérida Regina Nunes Salgado. (2016) A Critical Review of Analytical Methods for Determination of Ertapenem Sodium. Critical Reviews in Analytical Chemistry 46:1, pages 15-21.
Read now

Articles from other publishers (59)

TERRI LYNN SHIGLE & VICTORIA WEHR HANDY. 2024. Manual of Hematopoietic Cell Transplantation and Cellular Therapies. Manual of Hematopoietic Cell Transplantation and Cellular Therapies 145 165 .
Fernanda Cristina Gomes de Lima, Alberon Ribeiro de Araújo, Amanda Vasconcelos do Nascimento, Carmelita de Lima Bezerra Cavalcanti, Jorge Belém Oliveira Júnior, Jana Messias Sandes, Everton Morais da Silva, Catarina Fernandes de Freitas, Dyana Leal Veras, Luis Carlos Alves & Fábio André Brayner. (2023) In vitro evaluation of human intravenous immunoglobulin in combination with antimicrobials and human serum against multidrug-resistant isolates of Acinetobacter baumannii. Brazilian Journal of Microbiology 54:4, pages 2845-2856.
Crossref
Elipsha Sharma, Celine Kelso, Shuxin Zhang, Ying Guo, Muttucumaru Sivakumar & Guangming Jiang. (2023) Stability of Colistin and Carbapenems in Water and Wastewater. ACS ES&T Water 3:11, pages 3496-3504.
Crossref
Yu Wi, Ki Kwon, Cheon-Hoo Jeon, Si-Ho Kim, Soyoon Hwang, Sohyun Bae, Yoonjung Kim, Hyun-Ha Chang, Shin-Woo Kim, Hae Cheong, Shinwon Lee, Dong Jung, Kyung Sohn, Chisook Moon, Sang Heo, Bongyoung Kim, Mi Lee, Jian Hur, Jieun Kim & Young Yoon. (2023) Carbapenem Use in the Last Days of Life: A Nationwide Korean Study. Antibiotics 12:6, pages 964.
Crossref
Marziale Comito, Riccardo Monguzzi, Silvia Tagliapietra, Angelo Maspero, Giovanni Palmisano & Giancarlo Cravotto. (2023) From Batch to the Semi-Continuous Flow Hydrogenation of pNB, pNZ-Protected Meropenem. Pharmaceutics 15:5, pages 1322.
Crossref
Abhishek Tiwari, Varsha Tiwari, Biswa Mohan Sahoo, Bimal Krishna Banik, Manish Kumar & Navneet Verma. (2023) Carbapenem Antibiotics: Recent Update on Synthesis and Pharmacological Activities. Current Drug Research Reviews 15:1, pages 35-61.
Crossref
Guilherme da Costa de Souza, Cesar Augusto Roque‐Borda & Fernando R. Pavan. (2022) Beta‐lactam resistance and the effectiveness of antimicrobial peptides against KPC‐producing bacteria. Drug Development Research 83:7, pages 1534-1554.
Crossref
Ana Maria Raluca Gherman, Nicoleta Elena Dina & Vasile Chiș. (2022) Cheminformatics Study on Structural and Bactericidal Activity of Latest Generation β-Lactams on Widespread Pathogens. International Journal of Molecular Sciences 23:20, pages 12685.
Crossref
Sofus Vittrup, Maiken Stilling, Pelle Hanberg, Sara Kousgaard Tøstesen, Martin Bruun Knudsen, Josephine Olsen Kipp & Mats Bue. (2022) Concentrations of co-administered vancomycin and meropenem in the internal dead space of a cannulated screw and in cancellous bone adjacent to the screw – Evaluated by microdialysis in a porcine model. Injury 53:8, pages 2734-2740.
Crossref
Mina Yekani, Mohammad Ahangarzadeh Rezaee, Samad Beheshtirouy, Hossein Banazadeh Baghi, Ahad Bazmani, Abbas Farzinazar, Mohammad Yousef Memar & József Sóki. (2022) Carbapenem resistance in Bacteroides fragilis: A review of molecular mechanisms. Anaerobe 76, pages 102606.
Crossref
Nan Yang, Jing Wang, Yueliang Xie, Junjie Ding, Cuifang Wu, Jingjing Liu & Qi Pei. (2022) External Evaluation of Population Pharmacokinetic Models to Inform Precision Dosing of Meropenem in Critically Ill Patients. Frontiers in Pharmacology 13.
Crossref
Frank Jones, Yanmin Hu & Anthony Coates. (2022) The Efficacy of Using Combination Therapy against Multi-Drug and Extensively Drug-Resistant Pseudomonas aeruginosa in Clinical Settings. Antibiotics 11:3, pages 323.
Crossref
Erizka Rivani, Pepy Dwi Endraswari & Agung Dwi Wahyu Widodo. (2022) Growth kinetics of multiple Acinetobacter baumannii resistotype after meropenem-based antibiotic combination exposure. F1000Research 11, pages 762.
Crossref
Erizka Rivani, Pepy Dwi Endraswari & Agung Dwi Wahyu Widodo. (2022) Growth kinetics of multiple Acinetobacter baumannii resistotype after meropenem-based antibiotic combination exposure. F1000Research 11, pages 762.
Crossref
M. Nguyen & S.G. Joshi. (2021) Carbapenem resistance in Acinetobacter baumannii , and their importance in hospital‐acquired infections: a scientific review . Journal of Applied Microbiology 131:6, pages 2715-2738.
Crossref
Isabella Westermann, Silke Gastine, Carsten Müller, Wiebke Rudolph, Frank Peters, Frank Bloos, Mathias Pletz & Stefan Hagel. (2021) Population pharmacokinetics and probability of target attainment in patients with sepsis under renal replacement therapy receiving continuous infusion of meropenem: Sustained low‐efficiency dialysis and continuous veno‐venous haemodialysis. British Journal of Clinical Pharmacology 87:11, pages 4293-4303.
Crossref
Søren Brøgger Christensen. (2021) Drugs That Changed Society: History and Current Status of the Early Antibiotics: Salvarsan, Sulfonamides, and β-Lactams. Molecules 26:19, pages 6057.
Crossref
Jonathan Hiew, Timothy Whitmore, Mahalia McEvoy, Deborah Weatherall, Paul R. Ingram & Laurens Manning. (2021) Subcutaneous ertapenem delivered by an Australian outpatient parenteral antimicrobial therapy service: a retrospective comparative efficacy study. Internal Medicine Journal 51:10, pages 1717-1721.
Crossref
Pengxiang Zhou, Yahui Zhang, Zhenhuan Wang, Yingqiu Ying, Yan Xing, Xiaomei Tong & Suodi Zhai. (2021) Extended or Continuous Infusion of Carbapenems in Children with Severe Infections: A Systematic Review and Narrative Synthesis. Antibiotics 10:9, pages 1088.
Crossref
Zhenbao Ma, Zhenling Zeng, Jiao Liu, Chang Liu, Yu Pan, Yanan Zhang & Yafei Li. (2021) Emergence of IncHI2 Plasmid-Harboring blaNDM-5 from Porcine Escherichia coli Isolates in Guangdong, China. Pathogens 10:8, pages 954.
Crossref
Tomasz Bogiel, Mateusz Rzepka & Eugenia Gospodarek-Komkowska. (2021) An Application of Imipenem Discs or P. aeruginosa ATCC 27853 Reference Strain Increases Sensitivity of Carbapenem Inactivation Method for Non-Fermenting Gram-Negative Bacteria. Antibiotics 10:7, pages 875.
Crossref
Sharon Lechtig-Wasserman, Hans Liebisch-Rey, Nicolas Diaz-Pinilla, Jhosep Blanco, Yuli-Viviana Fuentes-Barreiro & Rosa-Helena Bustos. (2021) Carbapenem Therapeutic Drug Monitoring in Critically Ill Adult Patients and Clinical Outcomes: A Systematic Review with Meta-Analysis. Antibiotics 10:2, pages 177.
Crossref
Matthias Schmid, Oliver Steiner, Lisa Fasshold, Walter Goessler, Anna-Maria Holl & Klaus-Dieter Kühn. (2020) The stability of carbapenems before and after admixture to PMMA-cement used for replacement surgery caused by Gram-negative bacteria. European Journal of Medical Research 25:1.
Crossref
Gongli Zong, Chuanqing Zhong, Jiafang Fu, Yu Zhang, Peipei Zhang, Wenchi Zhang, Yan Xu, Guangxiang Cao & Rongzhen Zhang. (2020) The carbapenem resistance gene blaOXA-23 is disseminated by a conjugative plasmid containing the novel transposon Tn6681 in Acinetobacter johnsonii M19. Antimicrobial Resistance & Infection Control 9:1.
Crossref
Paul Skorup, Lisa Maudsdotter, Miklós Lipcsey, Anders Larsson & Jan Sjölin. (2020) Mode of bacterial killing affects the inflammatory response and associated organ dysfunctions in a porcine E. coli intensive care sepsis model. Critical Care 24:1.
Crossref
Fernanda Cristina Gomes de Lima, Jorge Belém Oliveira-Júnior, Carmelita de Lima Bezerra Cavalcanti, Dyana Leal Veras, Catarina Fernandes de Freitas, Jana Messias Sandes, Everton Morais da Silva, Daivyane Aline Mota da Rocha, Luiz Carlos Alves & Fabio André Brayner. (2020) Ultrastructural changes caused by the combination of intravenous immunoglobulin with meropenem, amikacin and colistin in multidrug-resistant Acinetobacter baumannii. Microbial Pathogenesis 149, pages 104437.
Crossref
Hongmei Wang, Namphi Nguyen & Christopher Cruz. (2020) Eravacycline for the treatment of complicated intra‐abdominal infections. Advances in Digestive Medicine.
Crossref
Mujeeb Ur Rehman, Hong Yang, Shaqiu Zhang, Yahui Huang, Rui Zhou, Siyue Gong, Qi Feng, Shuling Chen, Jing Yang, Zhishuang Yang, Muhammad Abbas, Min Cui, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Dekang Zhu, Xinxin Zhao, Ying Wu, Qiao Yang, Juan Huang, Ling Zhang, Yunya Liu, Yanling Yu, Bin Tian & Anchun Cheng. (2020) Emergence of Escherichia coli isolates producing NDM-1 carbapenemase from waterfowls in Hainan island, China. Acta Tropica 207, pages 105485.
Crossref
András Fodor, Birhan Addisie Abate, Péter Deák, László Fodor, Ervin Gyenge, Michael G. Klein, Zsuzsanna Koncz, Josephat Muvevi, László Ötvös, Gyöngyi Székely, Dávid Vozik & László Makrai. (2020) Multidrug Resistance (MDR) and Collateral Sensitivity in Bacteria, with Special Attention to Genetic and Evolutionary Aspects and to the Perspectives of Antimicrobial Peptides—A Review. Pathogens 9:7, pages 522.
Crossref
Osama Al-Quteimat & Alla Laila. (2019) Valproate Interaction With Carbapenems: Review and Recommendations. Hospital Pharmacy 55:3, pages 181-187.
Crossref
Svetlana Sadyrbaeva-Dolgova, Pilar Aznarte-Padial, Alberto Jimenez-Morales, Manuela Expósito-Ruiz, Miguel Ángel Calleja-Hernández & Carmen Hidalgo-Tenorio. (2020) Pharmacist recommendations for carbapenem de-escalation in urinary tract infection within an antimicrobial stewardship program. Journal of Infection and Public Health 13:4, pages 558-563.
Crossref
Anders Thorsted, Eva Tano, Kia Kaivonen, Jan Sjölin, Lena E. Friberg & Elisabet I. Nielsen. (2020) Extension of Pharmacokinetic/Pharmacodynamic Time-Kill Studies To Include Lipopolysaccharide/Endotoxin Release from Escherichia coli Exposed to Cefuroxime. Antimicrobial Agents and Chemotherapy 64:4.
Crossref
Tomonari SATO, Satoru MITSUBOSHI, Hiroki HOSOKAWA & Masami TSUGITA. (2020) Effect of Facility Characteristics and Medical Staff Associated with Adoption of Carbapenem in Hospitals: Questionnaire Survey in Niigata施設の特性および専門職種がカルバペネム系抗菌薬の採用状況に及ぼす影響―新潟県におけるアンケート調査. Japanese Journal of Infection Prevention and Control 35:1, pages 43-47.
Crossref
Juliette Patrier & Jean-François Timsit. (2019) Carbapenem use in critically ill patients. Current Opinion in Infectious Diseases, pages 1.
Crossref
Trevor Cross, Brett Ransegnola, Jung-Ho Shin, Anna Weaver, Kathy Fauntleroy, Michael S. VanNieuwenhze, Lars F. Westblade & Tobias Dörr. (2019) Spheroplast-Mediated Carbapenem Tolerance in Gram-Negative Pathogens. Antimicrobial Agents and Chemotherapy 63:9.
Crossref
Svetlana Sadyrbaeva-Dolgova, Pilar Aznarte-Padial, Juan Pasquau-Liaño, Manuela Expósito-Ruiz, Miguel Ángel Calleja Hernández & Carmen Hidalgo-Tenorio. (2019) Clinical outcomes of carbapenem de-escalation regardless of microbiological results: A propensity score analysis. International Journal of Infectious Diseases 85, pages 80-87.
Crossref
Wenjing Wu, Yu Feng, Guangmin Tang, Fu Qiao, Alan McNally & Zhiyong Zong. (2019) NDM Metallo-β-Lactamases and Their Bacterial Producers in Health Care Settings. Clinical Microbiology Reviews 32:2.
Crossref
Stephan Braune, Christina König, Jason A. Roberts, Axel Nierhaus, Oliver Steinmetz, Michael Baehr, Stefan Kluge & Claudia Langebrake. (2018) Pharmacokinetics of meropenem in septic patients on sustained low-efficiency dialysis: a population pharmacokinetic study. Critical Care 22:1.
Crossref
Elizabeth A. Lakota, Cornelia B. Landersdorfer, Li Zhang, Anne N. Nafziger, Joseph S. BertinoJrJr, Sujata M. Bhavnani & Alan Forrest. (2018) Population Pharmacokinetic Analyses for Ertapenem in Subjects with a Wide Range of Body Sizes. Antimicrobial Agents and Chemotherapy 62:10.
Crossref
Nashaat S. Hamza & Abdalla Khalil. 2018. Urinary Tract Infection - The Result of the Strength of the Pathogen, or the Weakness of the Host. Urinary Tract Infection - The Result of the Strength of the Pathogen, or the Weakness of the Host.
Francielli Mahnic de Vasconcellos, Monique Ribeiro Tiba-Casas, Laís Calissi Brisolla Tavares, William Vaz de Souza, Doroti de Oliveira Garcia & Carlos Henrique Camargo. (2017) Evaluation of a new trilocus sequence-based multiplex-PCR to detect major Acinetobacter baumannii clonal complexes circulating in Brazil. Infection, Genetics and Evolution 54, pages 4-6.
Crossref
Kazuhiro Oshima, Shigeki Nakamura, Naoki Iwanaga, Koji Takemoto, Taiga Miyazaki, Kastunori Yanagihara, Yoshitsugu Miyazaki, Hiroshi Mukae, Shigeru Kohno & Koichi Izumikawa. (2017) Efficacy of High-Dose Meropenem (Six Grams per Day) in Treatment of Experimental Murine Pneumonia Induced by Meropenem-Resistant Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy 61:1.
Crossref
Elias Dahdouh, Micheline Hajjar, Monica Suarez & Ziad Daoud. (2016) Acinetobacter baumannii Isolated from Lebanese Patients: Phenotypes and Genotypes of Resistance, Clonality, and Determinants of Pathogenicity. Frontiers in Cellular and Infection Microbiology 6.
Crossref
Ram Murgan Navaneethkrishnan & Sugumari Chandrasegaran. (2016) EVALUATION OF CLINICALLY IMPORTANT GRAM-NEGATIVE ISOLATES (ESCHERICHIA COLI, KLEBSIELLA PNEUMONIAE, PSEUDOMONAS AERUGINOSA) AND THEIR SUSCEPTIBILITY PATTERN IN TERTIARY CARE HOSPITAL: 3 YR PROSPECTIVE STUDY. Journal of Evolution of Medical and Dental Sciences 5:80, pages 5959-5963.
Crossref
Carmine G. Monteferrante, Sadaf Sultan, Marian T. ten Kate, Lennard J. M. Dekker, Katrin Sparbier, Markus Peer, Markus Kostzrewa, Theo M. Luider, Wil H. F. Goessens & Peter C. Burgers. (2016) Evaluation of different pretreatment protocols to detect accurately clinical carbapenemase-producing Enterobacteriaceae by MALDI-TOF. Journal of Antimicrobial Chemotherapy 71:10, pages 2856-2867.
Crossref
Terry King-Wing Ma, Chi Bon Leung, Kai Ming Chow, Bonnie Ching-Ha Kwan, Philip Kam-Tao Li & Cheuk Chun Szeto. (2016) Newer antibiotics for the treatment of peritoneal dialysis-related peritonitis. Clinical Kidney Journal 9:4, pages 616-623.
Crossref
Francisco Molina, Carlos Andrés Agudelo, Nelson Fonseca, Alicia Hidrón Botero, Carlos Andrés Jiménez, Álvaro Ochoa, Carlos Andrés Restrepo, Iván Mauricio Trompa & Gustavo Roncancio. (2016) Farmacocinética y farmacodinamia de los antibióticos en el paciente críticamente enfermo. Segunda parte. Acta Colombiana de Cuidado Intensivo 16:3, pages 156-171.
Crossref
Thatiany Cevallos Menegucci, James Albiero, Letícia Busato Migliorini, Janio Leal Borges Alves, Giselle Fukita Viana, Josmar Mazucheli, Floristher Elaine Carrara-Marroni, Celso Luiz Cardoso & Maria Cristina Bronharo Tognim. (2016) Strategies for the treatment of polymyxin B-resistant Acinetobacter baumannii infections. International Journal of Antimicrobial Agents 47:5, pages 380-385.
Crossref
Hae-Sun Chung, Dongeun Yong & Miae Lee. (2023) Mechanisms of Ertapenem Resistance in Enterobacteriaceae Isolates in a Tertiary University Hospital. Journal of Investigative Medicine 64:5, pages 1042-1049.
Crossref
Tara Anderson. 2016. Drug Dosing in Obesity. Drug Dosing in Obesity 53 62 .
J. Córdoba, N. M. Coronado-Álvarez, D. Parra & J. Parra-Ruiz. (2015) In Vitro Activities of Novel Antimicrobial Combinations against Extensively Drug-Resistant Acinetobacter baumannii . Antimicrobial Agents and Chemotherapy 59:12, pages 7316-7319.
Crossref
Matteo Bassetti & Elda Righi. (2015) New antibiotics and antimicrobial combination therapy for the treatment of gram-negative bacterial infections. Current Opinion in Critical Care 21:5, pages 402-411.
Crossref
Thu Q. Nguyen, Weirui Chai, Jane Gu, Katie Cook, Eugene Kim, Sam Goetz, Zach Farni, Monica Chepuru, Melina Cox, Pauline Nguyen, Hashim Raja, Patrick Magistrado, Faith Michael, Peter Oelschlaeger & John D. Buynak. (2015) Triethysilyl enol ethers in the synthesis of carbapenem precursors. Tetrahedron Letters 56:23, pages 3385-3389.
Crossref
Matteo Bassetti & Elda Righi. (2015) Development of novel antibacterial drugs to combat multiple resistant organisms. Langenbeck's Archives of Surgery 400:2, pages 153-165.
Crossref
Arzu Selen, Paul A. Dickinson, Anette Müllertz, John R. Crison, Hitesh B. Mistry, Maria T. Cruañes, Marilyn N. Martinez, Hans Lennernäs, Tim L. Wigal, David C. Swinney, James E. Polli, Abu T.M. Serajuddin, Jack A. Cook & Jennifer B. Dressman. (2014) The Biopharmaceutics Risk Assessment Roadmap for Optimizing Clinical Drug Product Performance. Journal of Pharmaceutical Sciences 103:11, pages 3377-3397.
Crossref
Zamani E. D. Cele, Sachin A. Pawar, Tricia Naicker, Glenn E. M. Maguire, Per I. Arvidsson, Hendrik G. Kruger & Thavendran Govender. (2014) Organocatalytic Mannich Reactions on a Carbapenem Core – Synthesis of Mannich Bases and Bicyclic Diazanonanes. European Journal of Organic Chemistry 2014:11, pages 2253-2260.
Crossref
Charles-Edouard Luyt, Alexandra Aubry, Qin Lu, Maïté Micaelo, Nicolas Bréchot, Florence Brossier, Hélène Brisson, Jean-Jacques Rouby, Jean-Louis Trouillet, Alain Combes, Vincent Jarlier & Jean Chastre. (2014) Imipenem, Meropenem, or Doripenem To Treat Patients with Pseudomonas aeruginosa Ventilator-Associated Pneumonia. Antimicrobial Agents and Chemotherapy 58:3, pages 1372-1380.
Crossref
L. Dortet, L. Brechard, K. Grenet, M.-S. Nguessan & P. Nordmann. (2013) Sri Lanka, another country from the Indian subcontinent with NDM-1-producing Enterobacteriaceae. Journal of Antimicrobial Chemotherapy 68:9, pages 2172-2173.
Crossref
Matteo Bassetti, Maria Merelli, Chiara Temperoni & Augusta Astilean. (2013) New antibiotics for bad bugs: where are we?. Annals of Clinical Microbiology and Antimicrobials 12:1, pages 22.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.