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Special Issue Articles

Chronic post-traumatic headache: clinical findings and possible mechanisms

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Read on this site (6)

Simon Driver, Megan Douglas, Megan Reynolds, Evan McShan, Chad Swank & Randi Dubiel. (2021) A narrative review of biopsychosocial factors which impact overweight and obesity for individuals with acquired brain injury. Brain Injury 35:9, pages 1075-1085.
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Jordan VanderEnde, Emma A. Bateman, Heather M. MacKenzie & Keith Sequeira. (2020) Use of CGRP receptor blocker erenumab in the management of post-traumatic headache: a case series of 5 women. Brain Injury 34:10, pages 1431-1434.
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Louise S Roper, Peter Nightingale, Zhangjie Su, James L Mitchell, Antonio Belli & Alexandra J Sinclair. (2017) Disability from posttraumatic headache is compounded by coexisting posttraumatic stress disorder. Journal of Pain Research 10, pages 1991-1996.
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Carol A. Courtney & César Fernández-de-las-Peñas. (2014) Unraveling the challenge of head and face pain. Journal of Manual & Manipulative Therapy 22:1, pages 1-1.
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Articles from other publishers (79)

QiLiang Chen, Vimala Bharadwaj, Karen-Amanda Irvine & J. David Clark. (2023) Mechanisms and treatments of chronic pain after traumatic brain injury. Neurochemistry International 171, pages 105630.
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Megan Rudolph, Caroline Kopruszinski, Chen Wu, Edita Navratilova, Todd J. Schwedt, David W. Dodick, Frank Porreca & Trent Anderson. (2023) Identification of brain areas in mice with peak neural activity across the acute and persistent phases of post-traumatic headache. Cephalalgia 43:11.
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Cecilia Martindale, Angela P. Presson, Todd J. Schwedt, K. C. Brennan & Melissa M. Cortez. (2023) Sensory hypersensitivities are associated with post‐traumatic headache‐related disability. Headache: The Journal of Head and Face Pain.
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Nicholas P. Cherup, Linda E. Robayo, Roberta Vastano, Loriann Fleming, Bonnie E. Levin & Eva Widerström-Noga. (2023) Neuropsychological Function in Traumatic Brain Injury and the Influence of Chronic Pain. Perceptual and Motor Skills 130:4, pages 1495-1523.
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Ker Rui Wong, David K. Wright, Marissa Sgro, Sabrina Salberg, Jesse Bain, Crystal Li, Mujun Sun, Stuart J. McDonald, Richelle Mychasiuk, Rhys D. Brady & Sandy R. Shultz. (2023) Persistent Changes in Mechanical Nociception in Rats With Traumatic Brain Injury Involving Polytrauma. The Journal of Pain 24:8, pages 1383-1395.
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Sabrina Salberg, Matthew Macowan, Glenn R. Yamakawa, Jaimie K. Beveridge, Melanie Noel, Benjamin J. Marsland & Richelle Mychasiuk. (2023) Gut instinct: Sex differences in the gut microbiome are associated with changes in adolescent nociception following maternal separation in rats. Developmental Neurobiology 83:5-6, pages 219-233.
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Mike Papenhoff & Marcel Dudda. (2023) Treatment of Persistent Posttraumatic Headache with the Anti-CGRP Receptor Antibody Erenumab: a Case Report. SN Comprehensive Clinical Medicine 5:1.
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Vimala N. Bharadwaj, Peyman Sahbaie, Xiaoyou Shi, Karen-Amanda Irvine, David C. Yeomans & J. David Clark. (2023) Effect of Voluntary Exercise on Endogenous Pain Control Systems and Post-traumatic Headache in Mice. The Journal of Pain.
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Edita Navratilova, Janice Oyarzo, Trent Anderson, Ron S Broide, Sudhakar R Subramaniam, Edwin J Vazquez-Cintron, Mitchell F Brin, Todd J Schwedt, David W Dodick & Frank Porreca. (2022) Preclinical assessment of onabotulinumtoxinA for the treatment of mild traumatic brain injury-related acute and persistent post-traumatic headache. Cephalalgia 42:11-12, pages 1194-1206.
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Emily Collett, Tianru Wang, Candice Todd, Anil Dosaj, Andrew Baker & Cindy Hunt. (2022) Enhanced education for adult patients with persistent post-concussion headaches: a randomized controlled trial. Concussion 7:3.
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Morgan Heinzelmann, Christine Woods, Bert B. Vargas & Mathew Stokes. (2022) Posttraumatic Headache. Seminars in Neurology 42:04, pages 428-440.
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Donald D. McGeary, Patricia A. Resick, Donald B. Penzien, Cindy A. McGeary, Timothy T. Houle, Blessen C. Eapen, Carlos A. Jaramillo, Paul S. Nabity, David E. Reed2nd2nd, John C. Moring, Lindsay M. Bira, Hunter R. Hansen, Stacey Young-McCaughan, Briana A. Cobos, Jim Mintz, Terence M. Keane & Alan L. Peterson. (2022) Cognitive Behavioral Therapy for Veterans With Comorbid Posttraumatic Headache and Posttraumatic Stress Disorder Symptoms. JAMA Neurology 79:8, pages 746.
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Adriana D. Valbuena Valecillos, David R. GaterJr.Jr. & Gemayaret Alvarez. (2022) Concomitant Brain Injury and Spinal Cord Injury Management Strategies: A Narrative Review. Journal of Personalized Medicine 12:7, pages 1108.
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Matthew PeaseMazen ZaherAlejandro J. LopezSiyuan YuTanya EgodageSuzan SemrocDooman ArefanBrian Jankowitz. (2022) Multicenter and prospective trial of anti-epileptics for early seizure prevention in mild traumatic brain injury with a positive computed tomography scan. Surgical Neurology International 13, pages 241.
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Alaina Bassett & Erik Vanstrum. (2022) Exploring Vestibular Assessment in Patients with Headache and Dizziness. Otolaryngologic Clinics of North America 55:3, pages 549-558.
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Kevin Liu, Esmeralda Madrigal, Joyce S. Chung, Joelle I. Broffman, Naomi Bennett, Andrea Tsai, Maheen M. Adamson, Odette A. Harris & Molly Timmerman. (2022) Headache Diary Mobile Application for Monitoring and Characterizing Posttraumatic Headaches. Journal of Head Trauma Rehabilitation 37:3, pages 171-177.
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Andrew Blumenfeld, Jennifer McVige & Kerry Knievel. (2022) Post-traumatic headache: Pathophysiology and management - A review. Journal of Concussion 6, pages 205970022210934.
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Julia Jessen, Özüm S. Özgül, Oliver Höffken, Peter Schwenkreis, Martin Tegenthoff & Elena K Enax-Krumova. (2021) Somatosensory dysfunction in patients with posttraumatic headache: A systematic review. Cephalalgia 42:1, pages 73-81.
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Julie M. Joyce, Leah J. Mercier, Mehak Stokoe, Parker L. La, Tiffany Bell, Julia M. Batycky, Chantel T. Debert & Ashley D. Harris. (2022) Glutamate, GABA and glutathione in adults with persistent post-concussive symptoms. NeuroImage: Clinical 36, pages 103152.
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Paolo Martelletti. 2022. Migraine in Medicine. Migraine in Medicine 883 1016 .
Paul S. Nabity, Carlos A. Jaramillo, Patricia A. Resick, Cindy A. McGeary, Blessen C. Eapen, Casey L. Straud, Willie J. Hale, Timothy T. Houle, Brett T. Litz, Jim Mintz, Donald B. Penzien, Stacey Young‐McCaughan, Terence M. Keane, Alan L. Peterson & Donald D. McGeary. (2021) Persistent posttraumatic headaches and functioning in veterans: Injury type can matter. Headache: The Journal of Head and Face Pain 61:9, pages 1334-1341.
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Melissa M Cortez, Leah Millsap, Natalie A Rea, Christopher Sciarretta & KC Brennan. (2021) Photophobia and allodynia in persistent post-traumatic headache are associated with higher disease burden. Cephalalgia 41:10, pages 1089-1099.
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Franck Amyot, Cillian E. Lynch, John Ollinger, J. Kent Werner, E. Silverman, Carol Moore, Cora Davis, L. Christine Turtzo, Ramon Diaz-Arrastia & Kimbra Kenney. (2021) Cerebrovascular Reactivity Measures Are Associated With Post-traumatic Headache Severity in Chronic TBI; A Retrospective Analysis. Frontiers in Physiology 12.
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Michael Vaninetti, Mike Lim, Aladdin Khalaf, Valerie Metzger-Smith, Matthew Flowers, Alphonsa Kunnel, Eric Yang, David Song, Lisa Lin, Alice Tsai, Roland Lee, Shahrokh Golshan & Albert Leung. (2021) fMRI findings in MTBI patients with headaches following rTMS. Scientific Reports 11:1.
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Milena D ZirovichMDMD, Sanjog S PangarkarMDMD, Christina ManhMDMD, Lucia ChenMSMS, Sitaram VangalaMSMS, David A ElashoffPhDPhD & Ifeoma Stella IzuchukwuMD, MPHMD, MPH. (2021) Botulinum Toxin Type A for the Treatment of Post-traumatic Headache: A Randomized, Placebo-Controlled, Cross-over Study. Military Medicine 186:5-6, pages 493-499.
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Caroline M Kopruszinski, Joelle M Turnes, Juliana Swiokla, Troy J Weinstein, Todd J Schwedt, David W Dodick, Trent Anderson, Edita Navratilova & Frank Porreca. (2021) CGRP monoclonal antibody prevents the loss of diffuse noxious inhibitory controls (DNIC) in a mouse model of post-traumatic headache. Cephalalgia 41:6, pages 749-759.
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Donald D. McGeary, Donald B. Penzien, Patricia A. Resick, Cindy A. McGeary, Carlos A. Jaramillo, Blessen C. Eapen, Stacey Young-McCaughan, Paul S. Nabity, John C. Moring, Timothy T. Houle, Terence M. Keane & Alan L. Peterson. (2021) Study design for a randomized clinical trial of cognitive-behavioral therapy for posttraumatic headache. Contemporary Clinical Trials Communications 21, pages 100699.
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Matthew Flowers, Albert Leung, Dawn M Schiehser, Valerie Metzger-Smith, Lisa Delano-Wood, Scott Sorg, Alphonsa Kunnel, Angeline Wong, Michael Vaninetti, Shahrokh Golshan & Roland Lee. (2021) Severities in persistent mild traumatic brain injury related headache is associated with changes in supraspinal pain modulatory functions. Molecular Pain 17, pages 174480692110378.
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Pa Hong, Yun Gyu Song & Sungwoo Paek. (2021) Possible effects of agent orange and posttraumatic stress disorder on hyperglycemia in Korean veterans from the US-Vietnam war. Medicine 100:25, pages e26508.
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Saima UsmaniLaura BalcerSteven GalettaMia Minen. (2021) Feasibility of Smartphone-Delivered Progressive Muscle Relaxation in Persistent Post-Traumatic Headache Patients. Journal of Neurotrauma 38:1, pages 94-101.
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Morgan O’Connor & Sanjog Pangarkar. 2021. Brain Injury Medicine. Brain Injury Medicine 171 175.e2 .
Momen K. Tageldeen, Sally A. N. Gowers, Chi L. Leong, Martyn G. Boutelle & Emmanuel M. Drakakis. (2020) Traumatic brain injury neuroelectrochemical monitoring: behind-the-ear micro-instrument and cloud application. Journal of NeuroEngineering and Rehabilitation 17:1.
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T. L. H. Chan & Y. W. Woldeamanuel. (2020) Exploring naturally occurring clinical subgroups of post-traumatic headache. The Journal of Headache and Pain 21:1.
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Albert Leung. (2020) Addressing chronic persistent headaches after MTBI as a neuropathic pain state. The Journal of Headache and Pain 21:1.
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Alejandro Labastida-Ramírez, Silvia Benemei, Maria Albanese, Antonina D’Amico, Giovanni Grillo, Oxana Grosu, Devrimsel Harika Ertem, Jasper Mecklenburg, Elena Petrovna Fedorova, Pavel Řehulka, Francesca Schiano di Cola, Javier Trigo Lopez, Nina Vashchenko, Antoinette MaassenVanDenBrink & Paolo Martelletti. (2020) Persistent post-traumatic headache: a migrainous loop or not? The clinical evidence. The Journal of Headache and Pain 21:1.
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Anthony F. Domenichiello, Jennifer R. Jensen, Daisy Zamora, Mark Horowitz, Zhi-Xin Yuan, Keturah Faurot, J. Douglas Mann, Andrew J. Mannes & Christopher E. Ramsden. (2020) Identifying oxidized lipid mediators as prognostic biomarkers of chronic posttraumatic headache. Pain 161:12, pages 2775-2785.
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T. W. McGlennon, J. N. Buchwald, Walter J. Pories, Fang Yu, Arthur Roberts, Eric P. Ahnfeldt, Rukmini Menon & Henry Buchwald. (2020) Bypassing TBI: Metabolic Surgery and the Link between Obesity and Traumatic Brain Injury—a Review. Obesity Surgery 30:12, pages 4704-4714.
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Donald D McGeary, Patricia A Resick, Donald B Penzien, Blessen C Eapen, Carlos Jaramillo, Cindy A McGeary, Paul S Nabity, Alan L Peterson, Stacey Young-McCaughan, Terence M Keane, David Reed, John Moring, Jason J Sico, Sanjog S Pangarkar & Timothy T Houle. (2020) Reason to doubt the ICHD-3 7-day inclusion criterion for mild TBI-related posttraumatic headache: A nested cohort study. Cephalalgia 40:11, pages 1155-1167.
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Shana A. B. Burrowes, Chandler Sours Rhodes, Timothy J. Meeker, Joel D. Greenspan, Rao P. Gullapalli & David A. Seminowicz. (2019) Decreased grey matter volume in mTBI patients with post-traumatic headache compared to headache-free mTBI patients and healthy controls: a longitudinal MRI study. Brain Imaging and Behavior 14:5, pages 1651-1659.
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Lou Grangeon, Emer O'Connor, Chun-Kong Chan, Layan Akijian, Thanh Mai Pham Ngoc & Manjit Singh Matharu. (2020) New insights in post-traumatic headache with cluster headache phenotype: a cohort study. Journal of Neurology, Neurosurgery & Psychiatry 91:6, pages 572-579.
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Claire E. Lunde & Christine B. Sieberg. (2020) Walking the Tightrope: A Proposed Model of Chronic Pain and Stress. Frontiers in Neuroscience 14.
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Caroline Arbour, Yasmine Bouferguene, Roxanne Beauregard, Gilles Lavigne & Alberto Herrero Babiloni. (2020) Update on the prevalence of persistent post-traumatic headache in adult civilian traumatic brain injury: protocol for a systematic review and meta-analysis. BMJ Open 10:1, pages e032706.
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Wolfgang LaubeWolfgang Laube. 2020. Sensomotorik und Schmerz. Sensomotorik und Schmerz 165 196 .
George G. A. Pujalte, Timothy M. Dekker, Andre A. Abadin & Trisha E. Jethwa. 2020. Concussion Management for Primary Care. Concussion Management for Primary Care 19 30 .
Ajal M. Dave, Jay C. Erickson & Brett J. Theeler. 2020. Traumatic Brain Injury. Traumatic Brain Injury 159 180 .
Edita Navratilova, Jill Rau, Janice Oyarzo, Jason Tien, Kimberly Mackenzie, Jennifer Stratton, Bethany Remeniuk, Todd Schwedt, Trent Anderson, David Dodick & Frank Porreca. (2019) CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice. Cephalalgia 39:14, pages 1762-1775.
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Sabrina Bouferguène, Alexandra Lapierre, Bérengère Houzé, Pierre Rainville & Caroline Arbour. (2019) Chronic Central Pain Among Community-Dwelling Survivors of Moderate-to-Severe Traumatic Brain Injury: A Quantitative Sensory Testing Study. Biological Research For Nursing 21:5, pages 519-531.
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Karen-Amanda Irvine, Peyman Sahbaie, Adam R. Ferguson & J. David Clark. (2019) Enhanced descending pain facilitation in acute traumatic brain injury. Experimental Neurology 320, pages 112976.
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Ajal DaveAravind GaneshMalik Muhammad AdilJack W. Tsao. (2019) Practice Current. Neurology Clinical Practice 9:3, pages 263-270.
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Christopher Mares, Jehane H. Dagher & Mona Harissi-Dagher. (2018) Narrative Review of the Pathophysiology of Headaches and Photosensitivity in Mild Traumatic Brain Injury and Concussion. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 46:1, pages 14-22.
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Teshamae S. Monteith & Tad Seifert. 2019. Neurosensory Disorders in Mild Traumatic Brain Injury. Neurosensory Disorders in Mild Traumatic Brain Injury 165 182 .
Maggie W. Waung & Morris Levin. 2019. Chronic Headache. Chronic Headache 357 381 .
Virginia B. Baker, Kathryn M. Eliasen & Nawaz K. Hack. (2018) Lifestyle modifications as therapy for medication refractory post-traumatic headache (PTHA) in the military population of Okinawa. The Journal of Headache and Pain 19:1.
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Samar Khoury & Rodrigo Benavides. (2018) Pain with traumatic brain injury and psychological disorders. Progress in Neuro-Psychopharmacology and Biological Psychiatry 87, pages 224-233.
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Emerson M. WickwireDavid M. SchnyerAnne GermainMichael T. SmithScott G. WilliamsChristopher J. LettieriAshlee B. McKeonSteven M. ScharfRyan StockerJennifer AlbrechtNeeraj BadjatiaAmy J. MarkowitzGeoffrey T. Manley. (2018) Sleep, Sleep Disorders, and Circadian Health following Mild Traumatic Brain Injury in Adults: Review and Research Agenda. Journal of Neurotrauma 35:22, pages 2615-2631.
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Andriy Glushakov, Olena Glushakova, Tetyana Korol, Sandra Acosta, Cesar Borlongan, Alex Valadka, Ronald Hayes & Alexander Glushakov. (2018) Chronic Upregulation of Cleaved-Caspase-3 Associated with Chronic Myelin Pathology and Microvascular Reorganization in the Thalamus after Traumatic Brain Injury in Rats. International Journal of Molecular Sciences 19:10, pages 3151.
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Karen-Amanda Irvine & J David Clark. (2018) Chronic Pain After Traumatic Brain Injury: Pathophysiology and Pain Mechanisms. Pain Medicine 19:7, pages 1315-1333.
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Albert Leung, Valerie Metzger-Smith, Yifan He, James Cordero, Brandon Ehlert, David Song, Lisa Lin, Shahrokh Golshan, Alice Tsai, Michael Vaninetti, Thomas Rutledge, Greg Polston, Robert Sheu & Roland Lee. (2018) Left Dorsolateral Prefrontal Cortex rTMS in Alleviating MTBI Related Headaches and Depressive Symptoms. Neuromodulation: Technology at the Neural Interface 21:4, pages 390-401.
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Tonia Sabo, Charlene Supnet & Sushmita Purkayastha. (2017) Secondary intracranial hypertension (pseudotumor cerebri) presenting as post-traumatic headache in mild traumatic brain injury: a case series. Child's Nervous System 34:4, pages 681-690.
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Shanti M. Pinto, Maria F. Twichell & Luke C. Henry. (2017) Predictors of Pharmacological Intervention in Adolescents With Protracted Symptoms After Sports‐Related Concussion. PM&R 9:9, pages 847-855.
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Alan C. Goldhamer, Nathan Gershfeld, David M. Goldman & Toshia R. Myers. (2017) Challenging Case in Clinical Practice: Long-Term Relief from Chronic Posttraumatic Headache After Water-Only Fasting and an Exclusively Plant-Foods Diet. Alternative and Complementary Therapies 23:4, pages 129-131.
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Tad Seifert, Alicia Sufrinko, Robert Cowan, W. Scott Black, Dave Watson, Bill Edwards, Scott Livingston, Keith Webster, David Akers, Mathew Lively & Anthony P. Kontos. (2017) Comprehensive Headache Experience in Collegiate Student‐Athletes: An Initial Report From the NCAA Headache Task Force. Headache: The Journal of Head and Face Pain 57:6, pages 877-886.
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James T. Eckner, Tad Seifert, Allison Pescovitz, Max Zeiger & Jeffrey S. Kutcher. (2017) Is Migraine Headache Associated With Concussion in Athletes? A Case–Control Study. Clinical Journal of Sport Medicine 27:3, pages 266-270.
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Albert Leung, Shivshil Shukla, Amir Fallah, David Song, Lisa Lin, Shahrokh Golshan, Alice Tsai, Amy Jak, Greg Polston & Roland Lee. (2016) Repetitive Transcranial Magnetic Stimulation in Managing Mild Traumatic Brain Injury-Related Headaches. Neuromodulation: Technology at the Neural Interface 19:2, pages 133-141.
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