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Modulation of Akt Activity by Doxorubicin in Breast Cancer Cells

Pages 334-336 | Published online: 18 Jul 2013

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Ahmed F. Salem, Gloria Bonuccelli, Generoso Bevilacqua, Hwyda Arafat, Richard G. Pestell, Federica Sotgia & Michael P. Lisanti. (2011) Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition. Cell Cycle 10:21, pages 3692-3700.
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Wang Kai, Shan Yating, Ma Lin, Yang Kaiyong, Hua Baojin, Yin Wu, Yin Fangzhou & Chen Yan. (2018) Natural product toosendanin reverses the resistance of human breast cancer cells to adriamycin as a novel PI3K inhibitor. Biochemical Pharmacology 152, pages 153-164.
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Hiroaki Kinoh, Yutaka Miura, Tsukasa Chida, Xueying Liu, Kazue Mizuno, Shigeto Fukushima, Yosuke Morodomi, Nobuhiro Nishiyama, Horacio Cabral & Kazunori Kataoka. (2016) Nanomedicines Eradicating Cancer Stem-like Cells in Vivo by pH-Triggered Intracellular Cooperative Action of Loaded Drugs . ACS Nano 10:6, pages 5643-5655.
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Andrea Turner, Liang-Cheng Li, Tania Pilli, Lixia Qian, Elizabeth Louise Wiley, Suman Setty, Konstantin Christov, Lakshmy Ganesh, Ajay V. Maker, Peifeng Li, Prasad Kanteti, Tapas K. Das Gupta & Bellur S. Prabhakar. (2013) MADD Knock-Down Enhances Doxorubicin and TRAIL Induced Apoptosis in Breast Cancer Cells. PLoS ONE 8:2, pages e56817.
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Yeon A. Choi, Jeong Su Park, Mi Young Park, Ki Sook Oh, Myung Sok Lee, Jong-Seok Lim, Keun Il Kim, Kun-yong Kim, Junhye Kwon, Do Young Yoon, Eun-Yi Moon & Young Yang. (2011) Increase in CIP2A expression is associated with doxorubicin resistance. FEBS Letters 585:5, pages 755-760.
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Ying Qu, Jinhua Wang, Myung-Shin Sim, Bingya Liu, Armando Giuliano, James Barsoum & Xiaojiang Cui. (2009) Elesclomol, counteracted by Akt survival signaling, enhances the apoptotic effect of chemotherapy drugs in breast cancer cells. Breast Cancer Research and Treatment 121:2, pages 311-321.
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Song Li, Yunfei Zhou, Ruiwen Wang, Haitao Zhang, Yan Dong & Clement Ip. (2007) Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates. Molecular Cancer Therapeutics 6:3, pages 1031-1038.
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Xinqun Li, Yang Lu, Ke Liang, Bolin Liu & Zhen Fan. (2005) Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells. Breast Cancer Research 7:5.
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