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Journal of Chemotherapy Volume 14, 2002 - Issue 4
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Articles

Comparison of 5-Fluorouracil and 5-Fluoro-2'-Deoxyuridine as an Effector in Radiation-Activated Prodrugs

Y. Shibamoto
,
Y. Mimasu
,
Y. Tachi
,
H. Hatta
&
S. Nishimoto
Pages 390-396 | Published online: 18 Jul 2013

Citations (11)

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Yuta Shibamoto, Chikao Sugie, Masato Ito & Hiroyuki Ogino. (2004) The Japanese experiences with hypoxia-targeting pharmacoradiotherapy: from hypoxic cell sensitisers to radiation-activated prodrugs. Expert Opinion on Pharmacotherapy 5:12, pages 2459-2467.
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Articles from other publishers (10)

Pooja DuaSajeesh SSoyoun KimDong-ki Lee. (2015) ALPPL2 Aptamer-Mediated Targeted Delivery of 5-Fluoro-2′-Deoxyuridine to Pancreatic Cancer. Nucleic Acid Therapeutics 25:4, pages 180-187.
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A. Miyakawa, Y. Shibamoto, S. Otsuka & H. Iwata. (2013) Applicability of the linear-quadratic model to single and fractionated radiotherapy schedules: an experimental study. Journal of Radiation Research 55:3, pages 451-454.
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Takeo Ito, Kazuhito Tanabe, Hisatsugu Yamada, Hiroshi Hatta & Sei-ichi Nishimoto. (2008) Radiation- and Photo-induced Activation of 5-Fluorouracil Prodrugs as a Strategy for the Selective Treatment of Solid Tumors. Molecules 13:10, pages 2370-2384.
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Alvaro A.A. de Queiroz, Gustavo A. Abraham & Olga Zazuco Higa. (2006) Controlled release of 5-fluorouridine from radiation-crosslinked poly(ethylene-co-vinyl acetate) films. Acta Biomaterialia 2:6, pages 641-650.
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Kazuhito Tanabe, Yuji Makimura, Yukihiro Tachi, Akemi Imagawa-Sato & Sei-ichi Nishimoto. (2005) Hypoxia-selective activation of 5-fluorodeoxyuridine prodrug possessing indolequinone structure: radiolytic reduction and cytotoxicity characteristics. Bioorganic & Medicinal Chemistry Letters 15:9, pages 2321-2324.
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Zhouen Zhang, Hiroshi Hatta, Kazuhito Tanabe & Sei-ichi Nishimot o. (2005) A New Class of 5-Fluoro-2?-deoxyuridine Prodrugs Conjugated with a Tumor-Homing Cyclic Peptide CNGRC by Ester Linkers: Synthesis, Reactivity, and Tumor-Cell?Selective Cytotoxicity. Pharmaceutical Research 22:3, pages 381-389.
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Hiroyuki OGINO, Yuta SHIBAMOTO, Chikao SUGIE & Masato ITO. (2005) Biological Effects of Intermittent Radiation in Cultured Tumor Cells: Influence of Fraction Number and Dose Per Fraction. Journal of Radiation Research 46:4, pages 401-406.
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Hao Jiang, Jing Lu, Ji Jiang & Pei Hu. (2004) Important Role of the Dihydrouracil/Uracil Ratio in Marked Interpatient Variations of Fluoropyrimidine Pharmacokinetics and Pharmacodynamics. The Journal of Clinical Pharmacology 44:11, pages 1260-1272.
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Yuta Shibamoto, Yukihiro Tachi, Kazuhito Tanabe, Hiroshi Hatta & Sei-Ichi Nishimoto. (2004) In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2′-deoxyuridine activated by hypoxic irradiation. International Journal of Radiation Oncology*Biology*Physics 58:2, pages 397-402.
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Yuta Shibamoto & Branislav Jeremic. (2004) Biologic premises of combined radiation therapy and chemotherapy in lung cancer. Hematology/Oncology Clinics of North America 18:1, pages 29-40.
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