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Case Reports

Lethal Toxicity After 5-Fluorouracil Chemotherapy and Its Possible Relationship to Dihydropyrimidine Dehydrogenase Deficiency: A Case Report and Review

Pages 599-603 | Published online: 18 Jul 2013

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Lev Bromberg. (2005) Intelligent hydrogels for the oral delivery of chemotherapeutics. Expert Opinion on Drug Delivery 2:6, pages 1003-1013.
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Hiroshi Yamashita, Masahiro Hiratsuka, Takahiro Mori, Wataru Shigeeda, Kenji Kaino, Nozomi Koyamada, Yorihiro Akamatsu, Keiji Abe, Shukichi Miyazaki & Michihiko Kitamura. (2015) Dihydropyrimidinase Deficiency with Severe 5-fluorouracil Toxicity Caused by Capecitabine. The Japanese Journal of Gastroenterological Surgery 48:7, pages 644-649.
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Göran Carlsson, Elisabeth Odin, Bengt Gustavsson & Yvonne Wettergren. (2014) Pretherapeutic uracil and dihydrouracil levels in saliva of colorectal cancer patients are associated with toxicity during adjuvant 5-fluorouracil-based chemotherapy. Cancer Chemotherapy and Pharmacology 74:4, pages 757-763.
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Yvonne Wettergren, Göran Carlsson, Elisabeth Odin & Bengt Gustavsson. (2011) Pretherapeutic uracil and dihydrouracil levels of colorectal cancer patients are associated with sex and toxic side effects during adjuvant 5‐fluorouracil–based chemotherapy. Cancer 118:11, pages 2935-2943.
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Walter Krugluger, Anita Brandstaetter, Enikö Kállay, Johann Schueller, Elisabeth Krexner, Stefan Kriwanek, Elisabeth Bonner & Heide S. Cross. (2007) Regulation of Genes of the Circadian Clock in Human Colon Cancer: Reduced Period-1 and Dihydropyrimidine Dehydrogenase Transcription Correlates in High-Grade Tumors. Cancer Research 67:16, pages 7917-7922.
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. (2005) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 14:7, pages i-xii.
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