Citations (141)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (15)
Ashutosh Singh, Sandesh Kumar Patel, Prateek Kumar, Kanhu Charan Das, Deepanshu Verma, Rohit Sharma, Timir Tripathi, Rajanish Giri, Natália Martins & Neha Garg. (2022) Quercetin acts as a P-gp modulator via impeding signal transduction from nucleotide-binding domain to transmembrane domain. Journal of Biomolecular Structure and Dynamics 40:10, pages 4507-4515.
Read now
Read now
Priyadeep Bhutani, Prabhakar K. Rajanna & Atish T. Paul. (2020) Impact of quercetin on pharmacokinetics of quetiapine: insights from in-vivo studies in wistar rats. Xenobiotica 50:12, pages 1483-1489.
Read now
Read now
Rene Christena Lowrence, Selva Ganesan Subramaniapillai, Venkatasubramanian Ulaganathan & Saisubramanian Nagarajan. (2019) Tackling drug resistance with efflux pump inhibitors: from bacteria to cancerous cells. Critical Reviews in Microbiology 45:3, pages 334-353.
Read now
Read now
Shoushan Li, Ting Yan, Rong Deng, Xuesong Jiang, Huaping Xiong, Yuan Wang, Qiao Yu, Xiaohua Wang, Cheng Chen & Yichao Zhu. (2017) Low dose of kaempferol suppresses the migration and invasion of triple-negative breast cancer cells by downregulating the activities of RhoA and Rac1. OncoTargets and Therapy 10, pages 4809-4819.
Read now
Read now
Kang Liu, Weijuan Chen, Tingting Yang, Baofang Wen, Dejun Ding, Michael Keidar, Jinbao Tang & Weifen Zhang. (2017) Paclitaxel and quercetin nanoparticles co-loaded in microspheres to prolong retention time for pulmonary drug delivery. International Journal of Nanomedicine 12, pages 8239-8255.
Read now
Read now
Ehsan Hejazi, Maryam Tavakoli, Mahmood Jeddi-Tehrani, Masoud Kimiagar, Jalal Hejazi, Mohammad Houshyari, Zohre Amiri, Hale Edalatkhah, Javad Nasrollahzadeh & Farah Idali. (2017) Investigating the Antiangiogenic, Anti-drug Resistance and Apoptotic Effects of Soy Isoflavone Extract Alone or in Combination with Docetaxel on Murine 4T1 Breast Tumor Model. Nutrition and Cancer 69:7, pages 1036-1042.
Read now
Read now
Jun Yu, Peng Zhou, James Asenso, Xiao-Dan Yang, Chun Wang & Wei Wei. (2016) Advances in plant-based inhibitors of P-glycoprotein. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 867-881.
Read now
Read now
Saad A. Hussain, Amal A. Sulaiman, Curt Balch, Harsh Chauhan, Qasim M. Alhadidi & Amit K. Tiwari. (2016) Natural Polyphenols in Cancer Chemoresistance. Nutrition and Cancer 68:6, pages 879-891.
Read now
Read now
Isha Taneja, Kanumuri Siva Rama Raju & Muhammad Wahajuddin. (2016) Dietary Isoflavones as Modulators of Drug Metabolizing Enzymes and Transporters: Effect on Prescription Medicines. Critical Reviews in Food Science and Nutrition 56:sup1, pages S95-S109.
Read now
Read now
Huizhen Wang, Yuqing Cui, Qingxue Fu, Bing Deng, Guowen Li, Jun Yang, Tao Wu & Yan Xie. (2015) A phospholipid complex to improve the oral bioavailability of flavonoids. Drug Development and Industrial Pharmacy 41:10, pages 1693-1703.
Read now
Read now
Kai Ni, Lei Yang, Chuanxing Wan, Yuanzheng Xia & Lingyi Kong. (2014) Flavonostilbenes from Sophora alopecuroides L. as multidrug resistance associated protein 1 (MRP1) inhibitors. Natural Product Research 28:23, pages 2195-2198.
Read now
Read now
C.-Q. Xiao, R. Chen, J. Lin, G. Wang, Y. Chen, Z.-R. Tan & H.-H. Zhou. (2012) Effect of genistein on the activities of cytochrome P450 3A and P-glycoprotein in Chinese healthy participants. Xenobiotica 42:2, pages 173-178.
Read now
Read now
Naseem Akhtar, Abdul Ahad, Roop Kishan Khar, Manu Jaggi, Mohammed Aqil, Zeenat Iqbal, Farhan Jalees Ahmad & Sushama Talegaonkar. (2011) The emerging role of P-glycoprotein inhibitors in drug delivery: a patent review. Expert Opinion on Therapeutic Patents 21:4, pages 561-576.
Read now
Read now
Wenxia Zhang, Yi Han, Siok Lam Lim & Lee Yong Lim. (2009) Dietary regulation of P-gp function and expression. Expert Opinion on Drug Metabolism & Toxicology 5:7, pages 789-801.
Read now
Read now
Jing Shen, Weijing Zhang, Jun Wu & Yunfeng Zhu. (2008) The synergistic reversal effect of multidrug resistance by quercetin and hyperthermia in doxorubicin-resistant human myelogenous leukemia cells. International Journal of Hyperthermia 24:2, pages 151-159.
Read now
Read now
Articles from other publishers (126)
Amer E. Alkhalifa, Nour F. Al-Ghraiybah, Julia Odum, John G. Shunnarah, Nataleigh Austin & Amal Kaddoumi. (2023) Blood–Brain Barrier Breakdown in Alzheimer’s Disease: Mechanisms and Targeted Strategies. International Journal of Molecular Sciences 24:22, pages 16288.
Crossref
Crossref
Pavan Kumar Chintamaneni, Sai Kiran S.S. Pindiprolu, Nandhakumar Sathyamoorthy, Motamarri Venkata Naga Lalitha Chaitanya, Rashmi Saxena Pal & Malakapogu Ravindra Babu. 2023. Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach. Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach
284
303
.
Solmaz Asnaashari, Elham Amjad & Babak Sokouti. (2023) Synergistic effects of flavonoids and paclitaxel in cancer treatment: a systematic review. Cancer Cell International 23:1.
Crossref
Crossref
Sonam Grewal, Teenu Sharma & Rajan Swami. (2023) New era of nanoparticles facilitated co-delivery in cancer therapy: two heads are better than one. Journal of Nanoparticle Research 25:9.
Crossref
Crossref
Mina Homayoonfal, Hamidreza Gilasi, Zatollah Asemi, Mahmood Khaksary Mahabady, Reza Asemi & Bahman Yousefi. (2023) Quercetin modulates signal transductions and targets non-coding RNAs against cancer development. Cellular Signalling 107, pages 110667.
Crossref
Crossref
Yajuan Bi, Xue Wang, Hui Ding, Feng He, Lifeng Han & Youcai Zhang. (2022) Transporter-mediated Natural Product-Drug Interactions. Planta Medica 89:02, pages 119-133.
Crossref
Crossref
Prarthana Chatterjee, Suchetana Gupta & Satarupa Banerjee. 2023. Recent Frontiers of Phytochemicals. Recent Frontiers of Phytochemicals
261
293
.
T. A. Fedotcheva & N. L. Shimanovsky. (2023) Pharmacological Strategies for Overcoming Multidrug Resistance to Chemotherapy. Pharmaceutical Chemistry Journal 56:10, pages 1307-1313.
Crossref
Crossref
Aleksandra Golonko, Adam Jan Olichwier, Renata Swislocka, Lukasz Szczerbinski & Włodzimierz Lewandowski. (2022) Why Do Dietary Flavonoids Have a Promising Effect as Enhancers of Anthracyclines? Hydroxyl Substituents, Bioavailability and Biological Activity. International Journal of Molecular Sciences 24:1, pages 391.
Crossref
Crossref
Maryam Nakhjavani & Sarah Shigdar. (2022) Natural Blockers of PD-1/PD-L1 Interaction for the Immunotherapy of Triple-Negative Breast Cancer-Brain Metastasis. Cancers 14:24, pages 6258.
Crossref
Crossref
Malak Yahia Qattan, Mohammad Idreesh Khan, Shudayyed Hasham Alharbi, Amit Kumar Verma, Fatimah A. Al-Saeed, Alduwish Manal Abduallah & Azza A. Al Areefy. (2022) Therapeutic Importance of Kaempferol in the Treatment of Cancer through the Modulation of Cell Signalling Pathways. Molecules 27:24, pages 8864.
Crossref
Crossref
Carlos Caro, Mehrab Pourmadadi, Mohammad Mahdi Eshaghi, Erfan Rahmani, Shirin Shojaei, Ana Cláudia Paiva-Santos, Abbas Rahdar, Razieh Behzadmehr, Maria Luisa García-Martín & Ana M. Díez-Pascual. (2022) Nanomaterials loaded with Quercetin as an advanced tool for cancer treatment. Journal of Drug Delivery Science and Technology 78, pages 103938.
Crossref
Crossref
Parina Asgharian, Abbas Pirpour Tazekand, Kamran Hosseini, Haleh Forouhandeh, Tohid Ghasemnejad, Maryam Ranjbar, Muzaffar Hasan, Manoj Kumar, Sohrab Minaei Beirami, Vahideh Tarhriz, Saiedeh Razi Soofiyani, Latipa Kozhamzharova, Javad Sharifi-Rad, Daniela Calina & William C. Cho. (2022) Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets. Cancer Cell International 22:1.
Crossref
Crossref
María Daniela Santi, María Gabriela Ortega & Mariana Andrea Peralta. (2022)
A State-of-the-art Review and Prospective Therapeutic Applications
of Prenyl Flavonoids as Chemosensitizers against Antifungal Multidrug
Resistance in
Candida albicans
. Current Medicinal Chemistry 29:24, pages 4251-4281.
Crossref
Crossref
Wei Liu, Ying Han, Xin Xin, Liqing Chen, Yanhong Liu, Chao Liu, Xintong Zhang, Mingji Jin, Jingzhe Jin, Zhonggao Gao & Wei Huang. (2022) Biomimetic and temporal-controlled nanocarriers with ileum transporter targeting for achieving oral administration of chemotherapeutic drugs. Journal of Nanobiotechnology 20:1.
Crossref
Crossref
Dipti Srivastava, Aarti Yadav, Salma Naqvi, Himani Awasthi & Zeeshan Fatima. (2022) Efficacy of Flavonoids in Combating Fluconazole Resistant Oral Candidiasis. Current Pharmaceutical Design 28:21, pages 1703-1713.
Crossref
Crossref
Dake Cai, Jing Jin, Huichang Bi, Guoping Zhong, Minhua Zhou, Jianfen Guo, Yike Cai, Miaoyin Liang, Qiong Gu, Zixuan Hu, Yijing Lai, Zi Dai, Lingjie Li, Yuxing Chen, Haili Gao & Min Huang. (2022) Paclitaxel-Containing Extract Exerts Anti-Cancer Activity through Oral Administration in A549-Xenografted BALB/C Nude Mice: Synergistic Effect between Paclitaxel and Flavonoids or Lignoids. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-19.
Crossref
Crossref
Tippawan Siritientong, Daylia Thet, Janthima Methaneethorn & Nattawut Leelakanok. (2022) Pharmacokinetic Outcomes of the Interactions of Antiretroviral Agents with Food and Supplements: A Systematic Review and Meta-Analysis. Nutrients 14:3, pages 520.
Crossref
Crossref
ReginaJoyce E. Ferrer, MarcJustin C. Ong & SoniaD Jacinto. (2022) Extract of Codiaeum luzonicum Merr. overcomes multidrug resistance in human colon cancer cells by modulating P-glycoprotein. Asian Pacific Journal of Tropical Biomedicine 12:9, pages 400.
Crossref
Crossref
Ana C. Gonçalves, Márcio Rodrigues, José David Flores‐Félix, Gonçalo Campos, Ana R. Nunes, Alessandra Braga Ribeiro, Luís R. Silva & Gilberto Alves. (2021) Sweet cherry phenolics revealed to be promising agents in inhibiting P‐glycoprotein activity and increasing cellular viability under oxidative stress conditions: in vitro and in silico study. Journal of Food Science 87:1, pages 450-465.
Crossref
Crossref
Ohnmar Myint, Sakornniya Wattanapongpitak, Suchart Kothan, Chatchanok Udomtanakunchai, Singkome Tima & Montree Tungjai. (2022) Modulation of p-glycoprotein-mediated efflux pirarubicin in living multidrug-resistant K562/Dox cell lines by 4-hydroxybenzoic acid and 4-hydroxy-3-methoxybenzoic acid via impairment of the cellular energetic state. Toxicology Reports 9, pages 1443-1451.
Crossref
Crossref
Zufika Qamar, Muhammad Usama Ashhar, Annu, Farheen Fatima Qizilibash, Pravat Kumar Sahoo, Asgar Ali, Javed Ali & Sanjula Baboota. (2021) Lipid nanocarrier of selegiline augmented anti-Parkinson’s effect via P-gp modulation using quercetin. International Journal of Pharmaceutics 609, pages 121131.
Crossref
Crossref
Lakshmi Mohan. 2021. Alternative Medicine - Update. Alternative Medicine - Update.
Meizhu He, Lijie Xia & Jinyao Li. (2021) Potential Mechanisms of Plant-Derived Natural Products in the Treatment of Cervical Cancer. Biomolecules 11:10, pages 1539.
Crossref
Crossref
Hui Teng, Hongting Deng, Yuanju He, Qiyan Lv & Lei Chen. (2021) The role of dietary flavonoids for modulation of ATP binding cassette transporter mediated multidrug resistance. eFood 2:5, pages 234-246.
Crossref
Crossref
Mohammad Hassan Jokar, Sima Sedighi & Maliheh Moradzadeh. (2021) Differentiation-Inducing Activity of the Phyto-polyphenols Epigallocatechin-3-gallate and Kaempferol on NB4 Cells. Journal of Advances in Medical and Biomedical Research 29:137, pages 339-345.
Crossref
Crossref
Yajing Fang, Fuqiang Liang, Mengmeng Xia, Weiwei Cao, Siyi Pan, Ting Wu & Xiaoyun Xu. (2021) Structure-activity relationship and mechanism of flavonoids on the inhibitory activity of P-glycoprotein (P-gp)-mediated transport of rhodamine123 and daunorubicin in P-gp overexpressed human mouth epidermal carcinoma (KB/MDR) cells. Food and Chemical Toxicology 155, pages 112381.
Crossref
Crossref
M. Ganesan, G. Kanimozhi, B. Pradhapsingh, Haseeb A. Khan, Abdullah S. Alhomida, Aishah Ekhzaimy, GR Brindha & N. Rajendra Prasad. (2021) Phytochemicals reverse P-glycoprotein mediated multidrug resistance via signal transduction pathways. Biomedicine & Pharmacotherapy 139, pages 111632.
Crossref
Crossref
Yu-Ning Teng, Kun-I Lin, Yu-Chao Lin, Tran-Dinh Thang, Yu-Hsuan Lan & Chin-Chuan Hung. (2021) A novel flavonoid from Fissistigma cupreonitens, 5‑hydroxy‑7,8‑dimethoxyflavanone, competitively inhibited the efflux function of human P-glycoprotein and reversed cancer multi-drug resistance. Phytomedicine 85, pages 153528.
Crossref
Crossref
Nabeela Farhat, Abid Ali, Robert A. Bonomo & Asad U. Khan. (2020) Efflux pumps as interventions to control infection caused by drug-resistance bacteria. Drug Discovery Today 25:12, pages 2307-2316.
Crossref
Crossref
Abolfazl Mehdizadehkashi, Fatemeh Sadoughi & Mansooreh Samimi. (2020) Quercetin and cervical cancer: a view of great scope. Medicinal Chemistry Research 29:11, pages 1923-1934.
Crossref
Crossref
Rodrigo Santos Aquino de Araújo, Edeildo Ferreira da Silva-Junior, Thiago Mendonça de Aquino, Marcus Tullius Scotti, Hamilton M. Ishiki, Luciana Scotti & Francisco Jaime Bezerra Mendonça-Junior. (2020) Computer-Aided Drug Design Applied to Secondary Metabolites as Anticancer Agents. Current Topics in Medicinal Chemistry 20:19, pages 1677-1703.
Crossref
Crossref
Rida Zahra, Muhammad Furqan, Rahim Ullah, Aziz Mithani, Rahman Shah Zaib Saleem & Amir Faisal. (2020) A cell-based high-throughput screen identifies inhibitors that overcome P-glycoprotein (Pgp)-mediated multidrug resistance. PLOS ONE 15:6, pages e0233993.
Crossref
Crossref
Ruttiros Khonkarn, Krai Daowtak & Siriporn Okonogi. (2020) Chemotherapeutic Efficacy Enhancement in P-gp-Overexpressing Cancer Cells by Flavonoid-Loaded Polymeric Micelles. AAPS PharmSciTech 21:4.
Crossref
Crossref
Sabrina Dallavalle, Vladimir Dobričić, Loretta Lazzarato, Elena Gazzano, Miguel Machuqueiro, Ilza Pajeva, Ivanka Tsakovska, Nace Zidar & Roberta Fruttero. (2020) Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors. Drug Resistance Updates 50, pages 100682.
Crossref
Crossref
Sama Izadpanah, Parastoo Shabani, Ali Aghebati‐Maleki, Amir Baghbanzadeh, Ali Fotouhi, Amir Bisadi, Leili Aghebati‐Maleki & Behzad Baradaran. (2019) Prospects for the involvement of cancer stem cells in the pathogenesis of osteosarcoma. Journal of Cellular Physiology 235:5, pages 4167-4182.
Crossref
Crossref
Pooneh Soltantabar, Erika L. Calubaquib, Ebrahim Mostafavi, Michael C. Biewer & Mihaela C. Stefan. (2020) Enhancement of Loading Efficiency by Coloading of Doxorubicin and Quercetin in Thermoresponsive Polymeric Micelles. Biomacromolecules 21:4, pages 1427-1436.
Crossref
Crossref
Jinyun Dong, Zuodong Qin, Wei-Dong Zhang, Gang Cheng, Assaraf G. Yehuda, Charles R. AshbyJrJr, Zhe-Sheng Chen, Xiang-Dong Cheng & Jiang-Jiang Qin. (2020) Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update. Drug Resistance Updates 49, pages 100681.
Crossref
Crossref
Christopher S. Chambers, Jitka Viktorová, Kateřina Řehořová, David Biedermann, Lucie Turková, Tomáš Macek, Vladimír Křen & Kateřina Valentová. (2019) Defying Multidrug Resistance! Modulation of Related Transporters by Flavonoids and Flavonolignans. Journal of Agricultural and Food Chemistry 68:7, pages 1763-1779.
Crossref
Crossref
Ahmed R. Hamed, Nahla S. Abdel-Azim, Khaled A. Shams & Faiza M. Hammouda. (2019) Targeting multidrug resistance in cancer by natural chemosensitizers. Bulletin of the National Research Centre 43:1.
Crossref
Crossref
Rebeca Peñalva, Irene Esparza, Jorge Morales-Gracia, Carlos J. González-Navarro, Eneko Larrañeta & Juan M. Irache. (2019) Casein nanoparticles in combination with 2-hydroxypropyl-β-cyclodextrin improves the oral bioavailability of quercetin. International Journal of Pharmaceutics 570, pages 118652.
Crossref
Crossref
Amit Kumar & Vikas Jaitak. (2019) Natural products as multidrug resistance modulators in cancer. European Journal of Medicinal Chemistry 176, pages 268-291.
Crossref
Crossref
Muhammad Imran, Bahare Salehi, Javad Sharifi-Rad, Tanweer Aslam Gondal, Farhan Saeed, Ali Imran, Muhammad Shahbaz, Patrick Valere Tsouh Fokou, Muhammad Umair Arshad, Haroon Khan, Susana G. Guerreiro, Natália Martins & Leticia M. Estevinho. (2019) Kaempferol: A Key Emphasis to Its Anticancer Potential. Molecules 24:12, pages 2277.
Crossref
Crossref
Qingmei Ye, Kai Liu, Qun Shen, Qingyue Li, Jinghui Hao, Fangxuan Han & Ren-Wang Jiang. (2019) Reversal of Multidrug Resistance in Cancer by Multi-Functional Flavonoids. Frontiers in Oncology 9.
Crossref
Crossref
Nuggehally R Srinivas. (2019) Combination of flavonoids with azole drugs for fungal infections: key pharmacokinetic challenges. Future Microbiology 14:9, pages 733-738.
Crossref
Crossref
Mengmeng Xia, Yajing Fang, Weiwei Cao, Fuqiang Liang, Siyi Pan & Xiaoyun Xu. (2019) Quantitative Structure–Activity Relationships for the Flavonoid-Mediated Inhibition of P-Glycoprotein in KB/MDR1 Cells. Molecules 24:9, pages 1661.
Crossref
Crossref
Bianca Peterson, Morné Weyers, Jan Steenekamp, Johan Steyn, Chrisna Gouws & Josias Hamman. (2019) Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism. Pharmaceutics 11:1, pages 33.
Crossref
Crossref
Neeraj Tiwari, Arun Kumar, Ashish K. Singh, Surabhi Bajpai, Anand K. Agrahari, Dhiraj Kishore, Vinod K. Tiwari & Rakesh K. Singh. 2019. Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases. Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases
293
350
.
Ebenezer Olatunde Farombi, Afolabi Clement Akinmoladun & Solomon Eduviere Owumi. 2019. Encyclopedia of Food Chemistry. Encyclopedia of Food Chemistry
224
236
.
Hsiu-Ju Chen, Yun-Lung Chung, Chia-Ying Li, Ying-Tzu Chang, Charles Wang, Hsiang-Yen Lee, Hui-Yi Lin & Chin-Chuan Hung. (2018) Taxifolin Resensitizes Multidrug Resistance Cancer Cells via Uncompetitive Inhibition of P-Glycoprotein Function. Molecules 23:12, pages 3055.
Crossref
Crossref
Xiaojuan Zhang, Qingqing Pan, Lingyun Hao, Qing Lin, Xiangping Tian, Zhiying Zhang, Shanshan Wang & Hehe Wang. (2018) Preparation of magnetic fluorescent dual-drug nanocomposites for codelivery of kaempferol and paclitaxel. Journal of Wuhan University of Technology-Mater. Sci. Ed. 33:1, pages 256-262.
Crossref
Crossref
Maliheh Moradzadeh, Alijan Tabarraei, Hamid Reza Sadeghnia, Ahmad Ghorbani, Ashraf Mohamadkhani, Saiedeh Erfanian & Amirhossein Sahebkar. (2017) Kaempferol increases apoptosis in human acute promyelocytic leukemia cells and inhibits multidrug resistance genes. Journal of Cellular Biochemistry 119:2, pages 2288-2297.
Crossref
Crossref
Florence Lefranc, Nurhayat Tabanca & Robert Kiss. (2017) Assessing the anticancer effects associated with food products and/or nutraceuticals using in vitro and in vivo preclinical development-related pharmacological tests. Seminars in Cancer Biology 46, pages 14-32.
Crossref
Crossref
Gregory Ondieki, Makafui Nyagblordzro, Siambi Kikete, Rongjia Liang, Lili Wang & Xin He. (2017) Cytochrome P450 and P-Glycoprotein-Mediated Interactions Involving African Herbs Indicated for Common Noncommunicable Diseases. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-18.
Crossref
Crossref
Tassarut Chaisit, Pongpun Siripong & Suree Jianmongkol. (2017) Rhinacanthin-C enhances doxorubicin cytotoxicity via inhibiting the functions of P-glycoprotein and MRP2 in breast cancer cells. European Journal of Pharmacology 795, pages 50-57.
Crossref
Crossref
Chao Yang, Iris L.K. Wong, Kai Peng, Zhen Liu, Peng Wang, Tingfu Jiang, Tao Jiang, Larry M.C. Chow & Sheng Biao Wan. (2017) Extending the structure−activity relationship study of marine natural ningalin B analogues as P-glycoprotein inhibitors. European Journal of Medicinal Chemistry 125, pages 795-806.
Crossref
Crossref
Nitin Pal Kalia. 2017. Drug Resistance in Bacteria, Fungi, Malaria, and Cancer. Drug Resistance in Bacteria, Fungi, Malaria, and Cancer
307
323
.
D. Ravikumar Reddy, Amit Khurana, Swarna Bale, Ramu Ravirala, V. Samba Siva Reddy, M. Mohankumar & Chandraiah Godugu. (2016) Natural flavonoids silymarin and quercetin improve the brain distribution of co-administered P-gp substrate drugs. SpringerPlus 5:1.
Crossref
Crossref
Liang Zheng, Lijun Zhu, Min Zhao, Jian Shi, Yuhuan Li, Jia Yu, Huangyu Jiang, Jinjun Wu, Yunli Tong, Yuting Liu, Ming Hu, Linlin Lu & Zhongqiu Liu. (2016) In Vivo Exposure of Kaempferol Is Driven by Phase II Metabolic Enzymes and Efflux Transporters. The AAPS Journal 18:5, pages 1289-1299.
Crossref
Crossref
Xu Wu, Jiang Ma, Yang Ye & Ge Lin. (2016) Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb–drug interactions. Journal of Chromatography B 1026, pages 236-253.
Crossref
Crossref
Onnuri Bae, Yujin Seo, Youhoon Chong & Mi Kyoung Kim. (2016)
P-Glycoprotein Inhibition and Multidrug Resistance Reversing Activity of 7-
O
-Aminoalkylquercetin Derivatives
. Bulletin of the Korean Chemical Society 37:7, pages 989-990.
Crossref
Crossref
Juan Pablo Rigalli, Guillermo Nicolás Tocchetti, Maite Rocío Arana, Silvina Stella Maris Villanueva, Viviana Alicia Catania, Dirk Theile, María Laura Ruiz & Johanna Weiss. (2016) The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters. Cancer Letters 376:1, pages 165-172.
Crossref
Crossref
Markus Geisler, Aurélien Bailly & Maria Ivanchenko. (2016) Master and servant: Regulation of auxin transporters by FKBPs and cyclophilins. Plant Science 245, pages 1-10.
Crossref
Crossref
Xianchao Pan, Hu Mei, Sujun Qu, Shuheng Huang, Jiaying Sun, Li Yang & Hua Chen. (2016) Prediction and characterization of P-glycoprotein substrates potentially bound to different sites by emerging chemical pattern and hierarchical cluster analysis. International Journal of Pharmaceutics 502:1-2, pages 61-69.
Crossref
Crossref
N. Prasad, Ganesan Muthusamy, Mohana Shanmugam & Suresh Ambudkar. (2016) South Asian Medicinal Compounds as Modulators of Resistance to Chemotherapy and Radiotherapy. Cancers 8:3, pages 32.
Crossref
Crossref
Gongwen Liang, Na Li, Liping Ma, Zhonglian Qian, Yuwen Sun, Luwen Shi & Libo Zhao. (2016)
Effect of quercetin on the transport of ritonavir to the central nervous system
in vitro
and
in vivo
. Acta Pharmaceutica 66:1, pages 97-107.
Crossref
Crossref
Kantappa Halake, Mallinath Birajdar & Jonghwi Lee. (2016) Structural implications of polyphenolic antioxidants. Journal of Industrial and Engineering Chemistry 35, pages 1-7.
Crossref
Crossref
Alex J. Guseman, Kaliah Miller, Grace Kunkle, Galen P. Dively, Jeffrey S. Pettis, Jay D. Evans, Dennis vanEngelsdorp & David J. Hawthorne. (2016) Multi-Drug Resistance Transporters and a Mechanism-Based Strategy for Assessing Risks of Pesticide Combinations to Honey Bees. PLOS ONE 11:2, pages e0148242.
Crossref
Crossref
Chenfeng Xu, Yu Ding, Jiang Ni, Lifang Yin, Jianping Zhou & Jing Yao. (2016) Tumor-targeted docetaxel-loaded hyaluronic acid-quercetin polymeric micelles with p-gp inhibitory property for hepatic cancer therapy. RSC Advances 6:33, pages 27542-27556.
Crossref
Crossref
Grégory Gatouillat, Abdulmagid Alabdul Magid, Eric Bertin, Hassan El btaouri, Hamid Morjani, Catherine Lavaud & Claudie Madoulet. (2015) Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells. Phytomedicine 22:13, pages 1186-1194.
Crossref
Crossref
Keti Zeka, Ketan C. Ruparelia, Maria A. Continenza, Dimitrios Stagos, Francesco Vegliò & Randolph R.J. Arroo. (2015) Petals of Crocus sativus L. as a potential source of the antioxidants crocin and kaempferol. Fitoterapia 107, pages 128-134.
Crossref
Crossref
Sandra Prasch & Franz Bucar. (2015) Plant derived inhibitors of bacterial efflux pumps: an update. Phytochemistry Reviews 14:6, pages 961-974.
Crossref
Crossref
Kasi Pandima Devi, Dicson Sheeja Malar, Seyed Fazel Nabavi, Antoni Sureda, Jianbo Xiao, Seyed Mohammad Nabavi & Maria Daglia. (2015) Kaempferol and inflammation: From chemistry to medicine. Pharmacological Research 99, pages 1-10.
Crossref
Crossref
Iris L. K. Wong, Bao-Chao Wang, Jian Yuan, Liang-Xing Duan, Zhen Liu, Tao Liu, Xue-Min Li, Xuesen Hu, Xiao-Yu Zhang, Tao Jiang, Sheng-Biao Wan & Larry M. C. Chow. (2015) Potent and Nontoxic Chemosensitizer of P-Glycoprotein-Mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives. Journal of Medicinal Chemistry 58:11, pages 4529-4549.
Crossref
Crossref
Andrew J. McLachlan & Stephen J. Clarke. 2015. Phytotherapies. Phytotherapies
536
553
.
Suoyuan Li, Wei Sun, Hongsheng Wang, Dongqing Zuo, Yingqi Hua & Zhengdong Cai. (2015) Research progress on the multidrug resistance mechanisms of osteosarcoma chemotherapy and reversal. Tumor Biology 36:3, pages 1329-1338.
Crossref
Crossref
Yan-rong Ma, Jing Huang, Yun-yun Shao, Kang Ma, Guo-qiang Zhang, Yan Zhou, Rao Zhi, Hong-yan Qin & Xin-an Wu. (2015) Inhibitory effect of atenolol on urinary excretion of metformin via down-regulating multidrug and toxin extrusion protein 1 (rMate1) expression in the kidney of rats. European Journal of Pharmaceutical Sciences 68, pages 18-26.
Crossref
Crossref
Wei Zhou, Jinjun Shan, Shouchuan Wang, Baochang Cai & Liuqing Di. (2015) Transepithelial transport of phenolic acids in Flos Lonicerae Japonicae in intestinal Caco-2 cell monolayers. Food & Function 6:9, pages 3072-3080.
Crossref
Crossref
Denise M.T. Yu, Tony Huynh, Alan M. Truong, Michelle Haber & Murray D. Norris. 2015. ABC Transporters and Cancer. ABC Transporters and Cancer
139
170
.
Patricia Campos-Bedolla, Fruzsina R. Walter, Szilvia Veszelka & Mária A. Deli. (2014) Role of the Blood–Brain Barrier in the Nutrition of the Central Nervous System. Archives of Medical Research 45:8, pages 610-638.
Crossref
Crossref
Peramaiyan Rajendran, Thamaraiselvan Rengarajan, Natarajan Nandakumar, Rajendran Palaniswami, Yutaka Nishigaki & Ikuo Nishigaki. (2014) Kaempferol, a potential cytostatic and cure for inflammatory disorders. European Journal of Medicinal Chemistry 86, pages 103-112.
Crossref
Crossref
Ilaria Peluso, Husseen Manafikhi, Raffaella Reggi & Maura Palmery. (2014) Interference of flavonoids with fluorescent intracellular probes: Methodological implications in the evaluation of the oxidative burst by flow cytometry. Cytometry Part A 85:8, pages 663-677.
Crossref
Crossref
Vasudevan Aparna, Kesavan Dineshkumar, Narasumani Mohanalakshmi, Devadasan Velmurugan & Waheeta Hopper. (2014) Identification of Natural Compound Inhibitors for Multidrug Efflux Pumps of Escherichia coli and Pseudomonas aeruginosa Using In Silico High-Throughput Virtual Screening and In Vitro Validation. PLoS ONE 9:7, pages e101840.
Crossref
Crossref
C.P. Yu, Y.W. Hsieh, S.P. Lin, Y.C. Chi, P. Hariharan, P.D.L. Chao & Y.C. Hou. (2014) Potential modulation on P-glycoprotein and CYP3A by soymilk and miso: In vivo and ex-vivo studies. Food Chemistry 149, pages 25-30.
Crossref
Crossref
Jin Wen Bin, Iris L. K. Wong, Xuesen Hu, Zhang Xiao Yu, Li Fu Xing, Tao Jiang, Larry M. C. Chow & Wan Sheng Biao. (2013) Structure–Activity Relationship Study of Permethyl Ningalin B Analogues as P-Glycoprotein Chemosensitizers. Journal of Medicinal Chemistry 56:22, pages 9057-9070.
Crossref
Crossref
Pei-Wen Hsu, Chi-Sheng Shia, Shiuan-Pey Lin, Pei-Dawn Lee Chao, Shin-Hun Juang & Yu-Chi Hou. (2013) Potential Risk of Mulberry–Drug Interaction: Modulation on P-Glycoprotein and Cytochrome P450 3A. Journal of Agricultural and Food Chemistry 61:18, pages 4464-4469.
Crossref
Crossref
Goutham R Adelli. (2013) Phytochemicals in ocular health: Therapeutic potential and delivery challenges. World Journal of Pharmacology 2:1, pages 18.
Crossref
Crossref
Sanjeev Banerjee & Paulraj Rajamani. 2013. Natural Products. Natural Products
2175
2254
.
Yu-Li Lo. (2012) A Potential Daidzein Derivative Enhances Cytotoxicity of Epirubicin on Human Colon Adenocarcinoma Caco-2 Cells. International Journal of Molecular Sciences 14:1, pages 158-176.
Crossref
Crossref
Guanyu Wang, Jiawei Zhang, Luying Liu, Sherven Sharma & Qinghua Dong. (2012) Quercetin Potentiates Doxorubicin Mediated Antitumor Effects against Liver Cancer through p53/Bcl-xl. PLoS ONE 7:12, pages e51764.
Crossref
Crossref
Jaime A. Yáñez, Nagendra V. Chemuturi, Scott W. Womble, Casey L. Sayre & Neal M. Davies. 2012. FLAVONOID PHARMACOKINETICS. FLAVONOID PHARMACOKINETICS
281
319
.
Yu-Li Lo, Wanjen Wang & Cheng-Ta Ho. (2012) 7,3′,4′-Trihydroxyisoflavone modulates multidrug resistance transporters and induces apoptosis via production of reactive oxygen species. Toxicology 302:2-3, pages 221-232.
Crossref
Crossref
Serge A.L. Zander, Ariena Kersbergen, Wendy Sol, Maaike Gonggrijp, Koen van de Wetering, Jos Jonkers, Piet Borst & Sven Rottenberg. (2012) Lack of ABCG2 Shortens Latency of BRCA1-Deficient Mammary Tumors and This Is Not Affected by Genistein or Resveratrol. Cancer Prevention Research 5:8, pages 1053-1060.
Crossref
Crossref
Jian Yuan, Iris L.K. Wong, Tao Jiang, Si Wen Wang, Tao Liu, Bin Jin Wen, Larry M.C. Chow & Biao Wan Sheng. (2012) Synthesis of methylated quercetin derivatives and their reversal activities on P-gp- and BCRP-mediated multidrug resistance tumour cells. European Journal of Medicinal Chemistry 54, pages 413-422.
Crossref
Crossref
Pornsiri Pitchakarn, Shinobu Ohnuma, Komsak Pintha, Wilart Pompimon, Suresh V. Ambudkar & Pornngarm Limtrakul. (2012) Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance. The Journal of Nutritional Biochemistry 23:1, pages 76-84.
Crossref
Crossref
Meng-Shiou Lee, Chao-Jung Chen, Lei Wan, Ayano Koizumi, Wen-Te Chang, Meng-Ja Yang, Wen-Hsin Lin, Fuu-Jen Tsai & Ming-Kuem Lin. (2011) Quercetin is increased in heat-processed Cuscuta campestris seeds, which enhances the seed's anti-inflammatory and anti-proliferative activities. Process Biochemistry 46:12, pages 2248-2254.
Crossref
Crossref
Saravana Kumar Jaganathan. (2011) Can flavonoids from honey alter multidrug resistance?. Medical Hypotheses 76:4, pages 535-537.
Crossref
Crossref
Aurelie De Thonel, Valerie Mezger & Carmen Garrido. (2011) Implication of Heat Shock Factors in Tumorigenesis: Therapeutical Potential. Cancers 3:1, pages 1158-1181.
Crossref
Crossref
Sanjeev Banerjee, Dejuan Kong, Asfar S. Azmi, Zhiwei Wang, Aamir Ahmad, Seema Sethi & Fazlul H. Sarkar. (2010)
Retracted: Restoring sensitivity to oxaliplatin by a novel approach in gemcitabine‐resistant pancreatic cancer cells
in vitro
and
in vivo
. International Journal of Cancer 128:5, pages 1240-1250.
Crossref
Crossref
Wisinee Chanmahasathien, Chadarat Ampasavate, Harald Greger & Pornngarm Limtrakul. (2011) Stemona alkaloids, from traditional Thai medicine, increase chemosensitivity via P-glycoprotein-mediated multidrug resistance. Phytomedicine 18:2-3, pages 199-204.
Crossref
Crossref
Stella Chai, Kenneth KW To & Ge Lin. (2010) Circumvention of multi-drug resistance of cancer cells by Chinese herbal medicines. Chinese Medicine 5:1.
Crossref
Crossref
Chen Chen, Jane Zhou & Chunyan Ji. (2010) Quercetin: A potential drug to reverse multidrug resistance. Life Sciences 87:11-12, pages 333-338.
Crossref
Crossref
Elisabetta Chieli, Nadia Romiti, Idania Rodeiro & Gabino Garrido. (2010) In vitro modulation of ABCB1/P-glycoprotein expression by polyphenols from Mangifera indica. Chemico-Biological Interactions 186:3, pages 287-294.
Crossref
Crossref
Jorge F.S. Ferreira, Devanand L. Luthria, Tomikazu Sasaki & Arne Heyerick. (2010) Flavonoids from Artemisia annua L. as Antioxidants and Their Potential Synergism with Artemisinin against Malaria and Cancer. Molecules 15:5, pages 3135-3170.
Crossref
Crossref
H-W Xu, L Xu, J-H Hao, C-Y Qin & H Liu. (2010) Expression of P-Glycoprotein and Multidrug Resistance-Associated Protein is Associated with Multidrug Resistance in Gastric Cancer. Journal of International Medical Research 38:1, pages 34-42.
Crossref
Crossref
Ana I. Alvarez, Rebeca Real, Miriam Pérez, Gracia Mendoza, Julio G. Prieto & Gracia Merino. (2010) Modulation of the activity of ABC transporters (P-glycoprotein, MRP2, BCRP) by flavonoids and drug response. Journal of Pharmaceutical Sciences 99:2, pages 598-617.
Crossref
Crossref
Helen M. Coley. 2010. Multi-Drug Resistance in Cancer. Multi-Drug Resistance in Cancer
341
358
.
Li-rui Sun, Xun Li, Yan-na Cheng, Hong-yu Yuan, Ming-hui Chen, Wei Tang, Stephen Geoffrey Ward & Xian-jun Qu. (2009) Reversal effect of substituted 1,3-dimethyl-1H-quinoxalin-2-ones on multidrug resistance in adriamycin-resistant K562/A02 cells. Biomedicine & Pharmacotherapy 63:3, pages 202-208.
Crossref
Crossref
Ke Lan, Jian-lin He, Yang Tian, Fei Tan, Xue-hua Jiang, Ling Wang & Li-ming Ye. (2008) Intra-herb pharmacokinetics interaction between quercetin and isorhamentin. Acta Pharmacologica Sinica 29:11, pages 1376-1382.
Crossref
Crossref
Xiangrong Song, Yu Zhao, Shixiang Hou, Fangyuan Xu, Rongli Zhao, Junyao He, Zheng Cai, Yuanbo Li & Qiuhong Chen. (2008) Dual agents loaded PLGA nanoparticles: Systematic study of particle size and drug entrapment efficiency. European Journal of Pharmaceutics and Biopharmaceutics 69:2, pages 445-453.
Crossref
Crossref
Helen M. Coley. (2008) Mechanisms and strategies to overcome chemotherapy resistance in metastatic breast cancer. Cancer Treatment Reviews 34:4, pages 378-390.
Crossref
Crossref
Theo M. de Kok, Simone G. van Breda & Margaret M. Manson. (2008) Mechanisms of combined action of different chemopreventive dietary compounds. European Journal of Nutrition 47:S2, pages 51-59.
Crossref
Crossref
A. Alisi & C. Balsano. (2008) Enhancing the Efficacy of Hepatocellular Carcinoma Chemotherapeutics with Natural Anticancer Agents. Nutrition Reviews 65:12, pages 550-553.
Crossref
Crossref
Cristina Zanini, Giuliana Giribaldi, Giorgia Mandili, Franco Carta, Nicoletta Crescenzio, Brigitte Bisaro, Alessandra Doria, Luiselda Foglia, Luca Cordero di Montezemolo, Fabio Timeus & Franco Turrini. (2007) Inhibition of heat shock proteins (HSP) expression by quercetin and differential doxorubicin sensitization in neuroblastoma and Ewing’s sarcoma cell lines. Journal of Neurochemistry 103:4, pages 1344-1354.
Crossref
Crossref
Libin Huang, Chunhui Wang, Wenbin Zheng, Rui Liu, Jinlin Yang & Chengwei Tang. (2007) Effects of celecoxib on the reversal of multidrug resistance in human gastric carcinoma by downregulation of the expression and activity of P-glycoprotein. Anti-Cancer Drugs 18:9, pages 1075-1080.
Crossref
Crossref
P. Limtrakul, S. Siwanon, S. Yodkeeree & C. Duangrat. (2007) Effect of Stemona curtisii root extract on P-glycoprotein and MRP-1 function in multidrug-resistant cancer cells. Phytomedicine 14:6, pages 381-389.
Crossref
Crossref
Xiuguo Li & Jun-Shik Choi. (2007) Effect of genistein on the pharmacokinetics of paclitaxel administered orally or intravenously in rats. International Journal of Pharmaceutics 337:1-2, pages 188-193.
Crossref
Crossref
Soo Yeon Chung, Dae Sik Jang, Ah‐Reum Han, Jung Ok Jang, Youngjoo Kwon, Eun‐Kyoung Seo & Hwa Jeong Lee. (2007)
Modulation of P‐glycoprotein‐mediated resistance by kaempferol derivatives isolated from
Zingiber zerumbet
. Phytotherapy Research 21:6, pages 565-569.
Crossref
Crossref
Vanu Ramkumar Ramprasath, Gopalakrishnan Akila, Palanivelu Shanthi & Panchanatham Sachdanandam. (2007) Biochemical Evaluation of Glycoprotein Components, Lysosomal Enzymes and Marker Enzymes upon Kalpaamruthaa Administration in Experimental Mammary Carcinoma Rats. Journal of Health Science 53:6, pages 644-654.
Crossref
Crossref
K. Michalak, O. Wesołowska, N. Motohashi & A. B. Hendrich. 2007. Bioactive Heterocycles II. Bioactive Heterocycles II
223
302
.
Walter Brand, Maaike E. Schutte, Gary Williamson, Jelmer J. van Zanden, Nicole H.P. Cnubben, John P. Groten, Peter J. van Bladeren & Ivonne M.C.M. Rietjens. (2006) Flavonoid-mediated inhibition of intestinal ABC transporters may affect the oral bioavailability of drugs, food-borne toxic compounds and bioactive ingredients. Biomedicine & Pharmacotherapy 60:9, pages 508-519.
Crossref
Crossref
Ruining Liu, Xueli Wang, Yunan Zhao, Zhixing Wang & Lijun Du. (2006) The uptake behaviors of kaempferol and quercetin through rat primary cultured cortical neurons. Biomedical Chromatography 20:11, pages 1178-1184.
Crossref
Crossref
Khadidja Haïdara, Lolita Zamir, Qui-Wen Shi & Gerald Batist. (2006) The flavonoid Casticin has multiple mechanisms of tumor cytotoxicity action. Cancer Letters 242:2, pages 180-190.
Crossref
Crossref
Irma Meijerman, Jos H. Beijnen & Jan H.M. Schellens. (2006) Herb–Drug Interactions in Oncology: Focus on Mechanisms of Induction. The Oncologist 11:7, pages 742-752.
Crossref
Crossref
Nicole V. Soucy, Horace D. Parkinson, Mark A. Sochaski & Susan J. Borghoff. (2006) Kinetics of Genistein and Its Conjugated Metabolites in Pregnant Sprague-Dawley Rats Following Single and Repeated Genistein Administration. Toxicological Sciences 90:1, pages 230-240.
Crossref
Crossref
W. A. Peer & A. S. Murphy. 2006. The Science of Flavonoids. The Science of Flavonoids
239
268
.