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Antimicrobial Chemotherapy

In Vitro Antifungal Activity of Isavuconazole against 345 Mucorales Isolates Collected at Study Centers in Eight Countries

Pages 272-281 | Published online: 20 Nov 2013

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Behoavy Mahafaly Ralaizanaka, Chantelli Iamblaudiot Razafindrazoto, Eloïse Bolot, Georges Bors, Stéphanie Housson-Wetzel, Soloniaina Hélio Razafimahefa, Rado Manitrala Ramanampamonjy & Pierre Claude. (2022) Gastrointestinal Mucormycosis-Induced Massive Lower Gastrointestinal Bleeding, Rectal Perforation, and Pulmonary Embolism: A Long Diagnostic Pathway in a Case Report. Clinical and Experimental Gastroenterology 15, pages 145-151.
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Matthew W. McCarthy & Thomas J. Walsh. (2016) Emerging diagnostic and therapeutic options for treating mucormycosis. Expert Opinion on Orphan Drugs 4:12, pages 1253-1261.
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Laura L. Kovanda, Rochelle Maher & William W. Hope. (2016) Isavuconazonium sulfate: a new agent for the treatment of invasive aspergillosis and invasive mucormycosis. Expert Review of Clinical Pharmacology 9:7, pages 887-897.
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Monica A Donnelley, Elizabeth S Zhu & George R Thompson$suffix/text()$suffix/text(). (2016) Isavuconazole in the treatment of invasive aspergillosis and mucormycosis infections. Infection and Drug Resistance 9, pages 79-86.
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Suganthini Krishnan Natesan & Pranatharthi H Chandrasekar. (2016) Isavuconazole for the treatment of invasive aspergillosis and mucormycosis: current evidence, safety, efficacy, and clinical recommendations. Infection and Drug Resistance 9, pages 291-300.
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Maria N Chitasombat & Dimitrios P Kontoyiannis. (2015) The ‘cephalosporin era’ of triazole therapy: isavuconazole, a welcomed newcomer for the treatment of invasive fungal infections. Expert Opinion on Pharmacotherapy 16:10, pages 1543-1558.
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Seyedmojtaba Seyedmousavi, Paul E Verweij & Johan W Mouton. (2015) Isavuconazole, a broad-spectrum triazole for the treatment of systemic fungal diseases. Expert Review of Anti-infective Therapy 13:1, pages 9-27.
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Diego R Falci & Alessandro C Pasqualotto. (2013) Profile of isavuconazole and its potential in the treatment of severe invasive fungal infections. Infection and Drug Resistance 6, pages 163-174.
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Cecilia G. Carvalhaes, Paul R. Rhomberg, Michael D. Huband, Michael A. Pfaller & Mariana Castanheira. (2023) Antifungal Activity of Isavuconazole and Comparator Agents against Contemporaneous Mucorales Isolates from USA, Europe, and Asia-Pacific. Journal of Fungi 9:2, pages 241.
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Pankaj Chandley, Priyanka Subba & Soma Rohatgi. (2022) COVID-19-Associated Mucormycosis: A Matter of Concern Amid the SARS-CoV-2 Pandemic. Vaccines 10:8, pages 1266.
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Andrew M. Borman, Mark Fraser, Zoe Patterson, Michael D. Palmer & Elizabeth M. Johnson. (2021) In Vitro Antifungal Drug Resistance Profiles of Clinically Relevant Members of the Mucorales (Mucoromycota) Especially with the Newer Triazoles. Journal of Fungi 7:4, pages 271.
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Somayyeh Heydari, Davood Habibi, Ali Reza Faraji, Hassan keypour & Masoumeh Mahmoudabadi. (2021) An overview on the progress and development on the palladium catalyzed direct cyanation. Inorganica Chimica Acta 514, pages 119956.
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Frederic Lamoth & Dimitrios P. Kontoyiannis. (2019) Therapeutic Challenges of Non- Aspergillus Invasive Mold Infections in Immunosuppressed Patients . Antimicrobial Agents and Chemotherapy 63:11.
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Jon Salmanton-García, Danila Seidel, Philipp Koehler, Sibylle C Mellinghoff, Raoul Herbrecht, Nikolai Klimko, Zdeněk Ráčil, Iker Falces-Romero, Paul Ingram, Miguel-Ángel Benítez-Peñuela, José Yesid Rodríguez, Guillaume Desoubeaux, Aleksandra Barać, Carolina García-Vidal, Martin Hoenigl, Sanjay R Mehta, Matthew P Cheng, Galina Klyasova, Werner J Heinz, Nousheen Iqbal, Robert Krause, Helmut Ostermann, Olaf Penack, Enrico Schalk, Donald C Sheppard, Birgit Willinger, Hilmar Wisplinghoff, J Janne Vehreschild, Oliver A Cornely, Maria J G T Vehreschild, Reham Abdelaziz Khedr, Alberto Arencibia-Núñez, Martha Avilés-Robles, Ingo Banke, Ariful Basher, Keertilaxmi Benachinamardi, Harmut Bertz, Arunaloke Chakrabarti, Lubos Drgona, Jesús García-Martínez, Julio García-Rodríguez, Sandra Gräber, Georg Härter, Michael Klein, Michal Kouba, Dong-Gun Lee, Yohann Le Govic, Fabian Leo, Johan Maertens, Georg Maschmeyer, Lisa Meintker, Xiao-Dong Mo, Lena-Katharina Müller, Nicolas Müller, Jeremy Stephen Nel, Jan Novák, Atul Patel, Frieder Pfäfflin, Juan-Carlos Pozo-Laderas, Pedro Puerta-Alcalde, Azucena Rodríguez-Guardado, Roland Schroers, Vandana Shekar, Susan Shenoi, Gerda Silling, Donald Vinh, Salomón Waizel-Haiat, Mandy Yap Yee Yee, Peralam Yegneswaran Prakash & Pavel Žák. (2019) Matched-paired analysis of patients treated for invasive mucormycosis: standard treatment versus posaconazole new formulations (MoveOn). Journal of Antimicrobial Chemotherapy 74:11, pages 3315-3327.
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William R Otto, Barbara A Pahud & Dwight E Yin. (2019) Pediatric Mucormycosis: A 10-Year Systematic Review of Reported Cases and Review of the Literature. Journal of the Pediatric Infectious Diseases Society 8:4, pages 342-350.
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Brad Spellberg & Johan Maertens. 2019. Principles and Practice of Transplant Infectious Diseases. Principles and Practice of Transplant Infectious Diseases 577 589 .
Michael A. Pfaller, Paul R. Rhomberg, Nathan P. Wiederhold, Connie Gibas, Carmita Sanders, Hongxin Fan, James Mele, Laura L. Kovanda & Mariana Castanheira. (2018) In Vitro Activity of Isavuconazole against Opportunistic Fungal Pathogens from Two Mycology Reference Laboratories . Antimicrobial Agents and Chemotherapy 62:10.
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I. Hadrich & A. Ayadi. (2018) Epidemiology of antifungal susceptibility: Review of literature. Journal de Mycologie Médicale 28:3, pages 574-584.
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Galen M. Kabulski & Shawn H. MacVane. (2018) Isavuconazole pharmacokinetics in a patient with cystic fibrosis following bilateral orthotopic lung transplantation. Transplant Infectious Disease 20:3.
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J. Denis, M.-P. Ledoux, Y. Nivoix & R. Herbrecht. (2018) Isavuconazole: A new broad-spectrum azole. Part 1: In vitro activity. Journal de Mycologie Médicale 28:1, pages 8-14.
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J. Poissy, T. Duburcq, C. Thieffry, E. Decrucq-Parmentier & D. Mathieu. (2017) « Nouvelles » molécules anti-infectieuses. Quelle place en médecine intensive/réanimation pour l’isavuconazole ?“New” drugs for infectious diseases: Can isavuconazole be used in intensive care?. Médecine Intensive Réanimation.
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Derek Murrell, John B. Bossaer, Ronald Carico, Sam Harirforoosh & David Cluck. (2017) Isavuconazonium sulfate: a triazole prodrug for invasive fungal infections. International Journal of Pharmacy Practice 25:1, pages 18-30.
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Teclegiorgis Gebremariam, Nathan P. Wiederhold, Abdullah Alqarihi, Priya Uppuluri, Nkechi Azie, John E. EdwardsJrJr & Ashraf S. Ibrahim. (2017) Monotherapy or combination therapy of isavuconazole and micafungin for treating murine mucormycosis. Journal of Antimicrobial Chemotherapy 72:2, pages 462-466.
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Matt Shirley & Lesley J. Scott. (2016) Isavuconazole: A Review in Invasive Aspergillosis and Mucormycosis. Drugs 76:17, pages 1647-1657.
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Amit Desai, Laura Kovanda, Donna Kowalski, Qiaoyang Lu, Robert Townsend & Peter L. Bonate. (2016) Population Pharmacokinetics of Isavuconazole from Phase 1 and Phase 3 (SECURE) Trials in Adults and Target Attainment in Patients with Invasive Infections Due to Aspergillus and Other Filamentous Fungi. Antimicrobial Agents and Chemotherapy 60:9, pages 5483-5491.
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Shawn R. Lockhart & Elizabeth L. Berkow. (2016) Hot Topics in Antifungal Susceptibility Testing: a New Drug, a Bad Bug, Sweeping Caspofungin Testing under the Rug, and Solving the Epidemiological Cutoff Value Shrug. Clinical Microbiology Newsletter 38:13, pages 103-108.
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Nathan P. Wiederhold & Deanna A. Sutton. 2016. Biology of Microfungi. Biology of Microfungi 451 467 .
Anuradha Chowdhary, Pradeep Kumar Singh, Shallu Kathuria, Ferry Hagen & Jacques F. Meis. (2015) Comparison of the EUCAST and CLSI Broth Microdilution Methods for Testing Isavuconazole, Posaconazole, and Amphotericin B against Molecularly Identified Mucorales Species. Antimicrobial Agents and Chemotherapy 59:12, pages 7882-7887.
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Maiken Cavling Arendrup, Rasmus Hare Jensen & Joseph Meletiadis. (2015) In Vitro Activity of Isavuconazole and Comparators against Clinical Isolates of the Mucorales Order . Antimicrobial Agents and Chemotherapy 59:12, pages 7735-7742.
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Alessandro Busca, Anna Maria Tortorano & Livio Pagano. (2015) Reviewing the importance and evolution of fungal infections and potential antifungal resistance in haematological patients. Journal of Global Antimicrobial Resistance 3:4, pages 237-241.
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Marisa H. Miceli & Carol A. Kauffman. (2015) Isavuconazole: A New Broad-Spectrum Triazole Antifungal Agent. Clinical Infectious Diseases 61:10, pages 1558-1565.
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Jeffrey M. Rybak, Kayleigh R. Marx, Andrew T. Nishimoto & P. David Rogers. (2015) Isavuconazole: Pharmacology, Pharmacodynamics, and Current Clinical Experience with a New Triazole Antifungal Agent. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 35:11, pages 1037-1051.
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Jose F. Camargo, Danny Yakoub & Jeong Hee Cho-Vega. (2015) Successful Treatment of Primary Cutaneous Mucormycosis Complicating Anti-TNF Therapy with a Combination of Surgical Debridement and Oral Posaconazole. Mycopathologia 180:3-4, pages 187-192.
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Marisa H. Miceli & Carol A. Kauffman. (2015) Treatment Options for Mucormycosis. Current Treatment Options in Infectious Diseases 7:3, pages 142-154.
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Natasha N. Pettit & Peggy L. Carver. (2015) Isavuconazole. Annals of Pharmacotherapy 49:7, pages 825-842.
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Eric Myers & Elizabeth Dodds Ashley. (2015) Antifungal Drug Therapeutic Monitoring: What are the Issues?. Current Clinical Microbiology Reports 2:2, pages 55-66.
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Michelle R Ananda-Rajah & Dimitrios Kontoyiannis. (2015) Isavuconazole: a new extended spectrum triazole for invasive mold diseases. Future Microbiology 10:5, pages 693-708.
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Oliver A. Cornely, Angelika Böhme, Anne Schmitt-Hoffmann & Andrew J. Ullmann. (2015) Safety and Pharmacokinetics of Isavuconazole as Antifungal Prophylaxis in Acute Myeloid Leukemia Patients with Neutropenia: Results of a Phase 2, Dose Escalation Study. Antimicrobial Agents and Chemotherapy 59:4, pages 2078-2085.
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J. Viljoen, N. Azie, A.-H. Schmitt-Hoffmann & M. Ghannoum. (2015) A Phase 2, Randomized, Double-Blind, Multicenter Trial To Evaluate the Safety and Efficacy of Three Dosing Regimens of Isavuconazole Compared with Fluconazole in Patients with Uncomplicated Esophageal Candidiasis. Antimicrobial Agents and Chemotherapy 59:3, pages 1671-1679.
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Paul R. Ingram, Arul E. Suthananthan, Ruben Rajan, Todd M. Pryce, Kishore Sieunarine, Dianne J. Gardam & Christopher H. Heath. (2014) Cutaneous mucormycosis and motor vehicle accidents: Findings from an Australian case series. Medical Mycology 52:8, pages 819-825.
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Guanpingsheng Luo, Teclegiorgis Gebremariam, Hongkyu Lee, John E. EdwardsJr.Jr., Laura Kovanda & Ashraf S. Ibrahim. (2014) Isavuconazole Therapy Protects Immunosuppressed Mice from Mucormycosis. Antimicrobial Agents and Chemotherapy 58:4, pages 2450-2453.
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Michael A. Pfaller, Shawn A. Messer, Paul R. Rhomberg, Ronald N. Jones & Mariana Castanheira. (2013) In Vitro Activities of Isavuconazole and Comparator Antifungal Agents Tested against a Global Collection of Opportunistic Yeasts and Molds . Journal of Clinical Microbiology 51:8, pages 2608-2616.
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B. Rammaert, F. Lanternier, S. Poirée, R. Kania & O. Lortholary. (2012) Diabetes and mucormycosis: A complex interplay. Diabetes & Metabolism 38:3, pages 193-204.
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Andreas H. Groll & Dominik Schrey. (2010) The Current Role of Posaconazole in Managing Zygomycosis. Current Fungal Infection Reports 5:1, pages 29-33.
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A. Chakrabarti, M. R. Shivaprakash, I. Curfs-Breuker, A. Baghela, C. H. Klaassen & J. F. Meis. (2010) Apophysomyces elegans : Epidemiology, Amplified Fragment Length Polymorphism Typing, and In Vitro Antifungal Susceptibility Pattern . Journal of Clinical Microbiology 48:12, pages 4580-4585.
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George R. Thompson & Nathan P. Wiederhold. (2010) Isavuconazole: A Comprehensive Review of Spectrum of Activity of a New Triazole. Mycopathologia 170:5, pages 291-313.
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